Compounds > 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid

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6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid and Brain Ischemia

6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid has been researched along with Brain Ischemia in 9 studies

Research

Studies (9)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	4 (44.44)	18.2507
2000's	4 (44.44)	29.6817
2010's	1 (11.11)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Ayer, DE; Belonga, KL; Braughler, JM; Hall, ED; Houser, DJ; Jacobsen, EJ; VanDoornik, FJ	1
Balogh, GT; Fischer, J; Gere, A; Kis-Varga, A; Könczöl, A; Vukics, K	1
Bartolomé, B; Chioua, M; García, AG; Garrido, I; González-Lafuente, L; Ismaili, L; Marco-Contelles, J; Oset-Gasque, MJ; Revuelta, J; Samadi, A; Soriano, E; Tomassolli, I; Valderas, C; Villarroya, M	1
Boyle, JP; Brown, ST; Fearon, IM; Hudasek, K; Peers, C; Scragg, JL	1
Gupta, S; Sharma, SS	1
Kaundal, RK; Sharma, SS	1
Clemens, JA; Panetta, JA	1
Gladson, CL; Nielsen, VG; Parks, DA; Tan, S; Wang, Z; Zhou, F	1
Kim, YH; Koh, JY; Noh, KM	1

Reviews

1 review(s) available for 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid and Brain Ischemia

Article	Year
Neuroprotection by antioxidants in models of global and focal ischemia. Annals of the New York Academy of Sciences, 1994, Nov-17, Volume: 738 Topics: Animals; Antioxidants; Ascorbic Acid; Brain Ischemia; Chromans; Corpus Striatum; Hippocampus; Ischemic Attack, Transient; Male; Neurons; Rats; Rats, Wistar; Reperfusion Injury; Structure-Activity Relationship	1994

Other Studies

8 other study(ies) available for 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid and Brain Ischemia

Article	Year
2-(Aminomethyl)chromans that inhibit iron-dependent lipid peroxidation and protect against central nervous system trauma and ischemia. Journal of medicinal chemistry, 1992, Nov-13, Volume: 35, Issue:23 Topics: Animals; Antioxidants; Brain Ischemia; Central Nervous System; Chromans; Gerbillinae; Lipid Peroxidation; Male; Mice; Rats; Structure-Activity Relationship; Wounds and Injuries	1992
Nitrone derivatives of trolox as neuroprotective agents. Bioorganic & medicinal chemistry letters, 2005, Jun-15, Volume: 15, Issue:12 Topics: Animals; Antioxidants; Arterial Occlusive Diseases; Brain Ischemia; Cerebrovascular Circulation; Chromans; Free Radical Scavengers; Hydroxyl Radical; Infarction, Middle Cerebral Artery; Lipid Peroxidation; Mice; Neuroprotective Agents; Nitrogen Oxides; Structure-Activity Relationship	2005
Synthesis, structure, theoretical and experimental in vitro antioxidant/pharmacological properties of α-aryl, N-alkyl nitrones, as potential agents for the treatment of cerebral ischemia. Bioorganic & medicinal chemistry, 2011, Jan-15, Volume: 19, Issue:2 Topics: Antioxidants; Brain Ischemia; Cell Line, Tumor; Humans; Hydrogen Bonding; Hydroxyl Radical; Models, Theoretical; Nitrogen Oxides; Reactive Oxygen Species; Thermodynamics	2011
Hypoxic augmentation of Ca2+ channel currents requires a functional electron transport chain. The Journal of biological chemistry, 2005, Jun-10, Volume: 280, Issue:23 Topics: Alzheimer Disease; Amyloid beta-Peptides; Antioxidants; Ascorbic Acid; Biological Transport; Brain Ischemia; Calcium; Calcium Channels; Cell Line; Chromans; Electron Transport; Electrons; Electrophysiology; Ethidium; Humans; Hypoxia; Immunohistochemistry; Mitochondria; Neurodegenerative Diseases; Oxidants; Oxygen; Peptides; Reactive Oxygen Species; Rotenone; Superoxides; Transfection; Up-Regulation; Xanthine Oxidase	2005
Neuroprotective effects of trolox in global cerebral ischemia in gerbils. Biological & pharmaceutical bulletin, 2006, Volume: 29, Issue:5 Topics: Animals; Brain; Brain Chemistry; Brain Ischemia; Carotid Stenosis; Chromans; Gerbillinae; Lipid Peroxidation; Male; Motor Activity; Neuroprotective Agents	2006
Neuroprotective effects of 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (Trolox), an antioxidant in middle cerebral artery occlusion induced focal cerebral ischemia in rats. Neurological research, 2007, Volume: 29, Issue:3 Topics: Animals; Brain Ischemia; Chromans; Disease Models, Animal; DNA Fragmentation; Dose-Response Relationship, Drug; Functional Laterality; In Situ Nick-End Labeling; Infarction, Middle Cerebral Artery; Lipid Peroxidation; Male; Malondialdehyde; Neuroprotective Agents; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Time Factors	2007
Sustained hypoxia-ischemia results in reactive nitrogen and oxygen species production and injury in the premature fetal rabbit brain. Journal of neuropathology and experimental neurology, 1998, Volume: 57, Issue:6 Topics: Animals; Antioxidants; Ascorbic Acid; Brain; Brain Ischemia; Cell Death; Cell Survival; Chromans; Female; Free Radicals; Hypoxia, Brain; Nitrogen; Oxidative Stress; Pregnancy; Rabbits; Reactive Oxygen Species; Uterus	1998
Mediation by membrane protein kinase C of zinc-induced oxidative neuronal injury in mouse cortical cultures. Journal of neurochemistry, 1999, Volume: 72, Issue:4 Topics: Animals; Antioxidants; Brain Ischemia; Cell Death; Cells, Cultured; Chromans; Enzyme Inhibitors; Indoles; Lipid Peroxidation; Maleimides; Mice; Nerve Degeneration; Neuroglia; Neurons; Neurotoxins; Oxidative Stress; Phorbols; Protein Kinase C; Thiobarbituric Acid Reactive Substances; Zinc	1999