6-heptyne-2,5-diamine has been researched along with Leukemia L 1210 in 5 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bartholeyns, J; Casara, P; Mamont, P | 1 |
| Claverie, N; Mamont, PS | 1 |
| Bakic, M; Chan, D; Freireich, EJ; Marton, LJ; Zwelling, LA | 1 |
| Kramer, DL; Pera, PJ; Porter, CW; Sufrin, JR | 1 |
| Bergeron, RJ; Ganis, B; Kramer, DL; Marton, LJ; Porter, CW; Vinson, T | 1 |
5 other study(ies) available for 6-heptyne-2,5-diamine and Leukemia L 1210
| Article | Year |
|---|---|
Antitumor properties of (2R,5R)-6-heptyne-2,5-diamine, a new potent enzyme-activated irreversible inhibitor of ornithine decarboxylase, in rodents.
Topics: Alkynes; Animals; Antineoplastic Agents; Diamines; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Eflornithine; Female; Leukemia L1210; Leukemia P388; Liver Neoplasms, Experimental; Lung Neoplasms; Mammary Neoplasms, Experimental; Mice; Mice, Inbred Strains; Neoplasms, Experimental; Ornithine; Ornithine Decarboxylase Inhibitors; Rats; Rats, Inbred BUF | 1984 |
Comparative antitumor properties in rodents of irreversible inhibitors of L-ornithine decarboxylase, used as such or as prodrugs.
Topics: Administration, Oral; Alkynes; Animals; Diamines; Eflornithine; Injections, Intraperitoneal; Leukemia L1210; Lung Neoplasms; Mice; Mice, Inbred DBA; Ornithine Decarboxylase Inhibitors; Prodrugs; S-Adenosylmethionine; Time Factors; Tumor Cells, Cultured | 1989 |
Effect of polyamine depletion by alpha-difluoromethylornithine or (2R,5R)-6-heptyne-2,5-diamine on drug-induced topoisomerase II-mediated DNA cleavage and cytotoxicity in human and murine leukemia cells.
Topics: Alkynes; Amsacrine; Animals; Antineoplastic Agents; Cell Line; Cell Survival; Diamines; DNA; DNA Damage; DNA Topoisomerases, Type II; Eflornithine; Etoposide; Humans; Leukemia L1210; Leukemia, Myeloid, Acute; Mice; Ornithine Decarboxylase Inhibitors; Polyamines; Tumor Cells, Cultured | 1987 |
Comparison of the biological effects of four irreversible inhibitors of ornithine decarboxylase in two murine lymphocytic leukemia cell lines.
Topics: Alkynes; Animals; Biological Transport; Cell Cycle; Cell Survival; Diamines; Eflornithine; Leukemia L1210; Leukemia L5178; Leukemia, Lymphoid; Mice; Ornithine; Ornithine Decarboxylase Inhibitors; Polyamines; Purine-Nucleoside Phosphorylase; S-Adenosylmethionine | 1986 |
Comparison and characterization of growth inhibition in L1210 cells by alpha-difluoromethylornithine, an inhibitor of ornithine decarboxylase, and N1,N8-bis(ethyl)spermidine, an apparent regulator of the enzyme.
Topics: Adenosylmethionine Decarboxylase; Alkynes; Animals; Cells, Cultured; Diamines; Eflornithine; Leukemia L1210; Ornithine Decarboxylase Inhibitors; Polyamines; Spermidine | 1986 |