6-chloromelatonin has been researched along with Melanoma in 3 studies
Melanoma: A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of melatonin, its precursors and derivatives on the growth of cultured human uveal melanoma cells were studied." | 7.70 | Effects of melatonin, its precursors and derivatives on the growth of cultured human uveal melanoma cells. ( Hu, DN; McCormick, SA; Roberts, JE, 1998) |
| "Previous work has demonstrated that melatonin inhibits growth of cultured human uveal melanoma cells." | 7.70 | Melatonin receptors in human uveal melanocytes and melanoma cells. ( Hu, DN; Roberts, JE; Wiechmann, AF, 2000) |
| "In order to explore the potential oncostatic properties of the pineal hormone, melatonin, we have investigated its binding characteristics and functional effects in a human malignant melanoma (M-6) cell line." | 7.68 | Human malignant melanoma cells express high-affinity receptors for melatonin: antiproliferative effects of melatonin and 6-chloromelatonin. ( Crocker, C; Niles, LP; Ying, SW, 1993) |
| "The effects of melatonin, its precursors and derivatives on the growth of cultured human uveal melanoma cells were studied." | 3.70 | Effects of melatonin, its precursors and derivatives on the growth of cultured human uveal melanoma cells. ( Hu, DN; McCormick, SA; Roberts, JE, 1998) |
| "Previous work has demonstrated that melatonin inhibits growth of cultured human uveal melanoma cells." | 3.70 | Melatonin receptors in human uveal melanocytes and melanoma cells. ( Hu, DN; Roberts, JE; Wiechmann, AF, 2000) |
| "In order to explore the potential oncostatic properties of the pineal hormone, melatonin, we have investigated its binding characteristics and functional effects in a human malignant melanoma (M-6) cell line." | 3.68 | Human malignant melanoma cells express high-affinity receptors for melatonin: antiproliferative effects of melatonin and 6-chloromelatonin. ( Crocker, C; Niles, LP; Ying, SW, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ying, SW | 1 |
| Niles, LP | 1 |
| Crocker, C | 1 |
| Hu, DN | 2 |
| McCormick, SA | 1 |
| Roberts, JE | 2 |
| Wiechmann, AF | 1 |
3 other studies available for 6-chloromelatonin and Melanoma
| Article | Year |
|---|---|
Human malignant melanoma cells express high-affinity receptors for melatonin: antiproliferative effects of melatonin and 6-chloromelatonin.
Topics: Adenylyl Cyclase Inhibitors; Cell Division; Cell Membrane; Colforsin; Cyclic AMP; DNA, Neoplasm; Hum | 1993 |
Effects of melatonin, its precursors and derivatives on the growth of cultured human uveal melanoma cells.
Topics: Cell Division; Dose-Response Relationship, Drug; Humans; Kynurenine; Melanoma; Melatonin; Serotonin; | 1998 |
Melatonin receptors in human uveal melanocytes and melanoma cells.
Topics: Acetamides; Blotting, Southern; Choroid Neoplasms; Dose-Response Relationship, Drug; Gene Expression | 2000 |