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6-chloro-2-(1-piperazinyl)pyrazine and Disease Models, Animal

6-chloro-2-(1-piperazinyl)pyrazine has been researched along with Disease Models, Animal in 5 studies

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's3 (60.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Abrams, RPM; Bachani, M; Balasubramanian, A; Brimacombe, K; Dorjsuren, D; Eastman, RT; Hall, MD; Jadhav, A; Lee, MH; Li, W; Malik, N; Nath, A; Padmanabhan, R; Simeonov, A; Steiner, JP; Teramoto, T; Yasgar, A; Zakharov, AV1
Aizawa, H; Ito, Y; Mitani, A; Shimizu, T; Soma, M; Sugimoto, J; Sugiyama, K; Tanaka, K; Tanaka, M1
Canto-de-Souza, A; Furuya-da-Cunha, EM; Souza, RR1
Gomes, KS; Nunes-De-Souza, RL1
Duke, FD; Hamilton, EC; Neisewander, JL; Pentkowski, NS; Pockros, LA; Teer, AP; Thiel, KJ; Weber, SM1

Other Studies

5 other study(ies) available for 6-chloro-2-(1-piperazinyl)pyrazine and Disease Models, Animal

ArticleYear
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Drug Evaluation, Preclinical; High-Throughput Screening Assays; Immunocompetence; Inhibitory Concentration 50; Methacycline; Mice, Inbred C57BL; Protease Inhibitors; Quantitative Structure-Activity Relationship; Small Molecule Libraries; Vero Cells; Zika Virus; Zika Virus Infection

2020
Region-specific deletions of the glutamate transporter GLT1 differentially affect seizure activity and neurodegeneration in mice.
    Glia, 2018, Volume: 66, Issue:4

    Topics: Animals; Anticonvulsants; Brain; Cell Death; Disease Models, Animal; DNA-Binding Proteins; Excitatory Amino Acid Transporter 2; Forkhead Transcription Factors; Homeodomain Proteins; Male; Mice, Inbred C57BL; Mice, Knockout; Nerve Tissue Proteins; Neurodegenerative Diseases; Neurons; Nuclear Proteins; Pentylenetetrazole; Pyrazines; Receptors, N-Methyl-D-Aspartate; Seizures; Transcription Factors

2018
Rat exposure in mice with neuropathic pain induces fear and antinociception that is not reversed by 5-HT2C receptor activation in the dorsal periaqueductal gray.
    Behavioural brain research, 2016, 07-01, Volume: 307

    Topics: Analysis of Variance; Animals; Apomorphine; Disease Models, Animal; Dopamine Agonists; Dose-Response Relationship, Drug; Exploratory Behavior; Fear; Male; Mice; Microinjections; Pain Measurement; Periaqueductal Gray; Pyrazines; Rats; Rats, Long-Evans; Receptor, Serotonin, 5-HT2C; Sciatica; Serotonin Receptor Agonists

2016
Implication of the 5-HT2A and 5-HT2C (but not 5HT1A) receptors located within the periaqueductal gray in the elevated plus-maze test-retest paradigm in mice.
    Progress in neuro-psychopharmacology & biological psychiatry, 2009, Oct-01, Volume: 33, Issue:7

    Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Analysis of Variance; Animals; Anxiety; Behavior, Animal; Disease Models, Animal; Dose-Response Relationship, Drug; Male; Maze Learning; Mice; Microinjections; Motor Activity; Periaqueductal Gray; Pyrazines; Receptor, Serotonin, 5-HT1A; Receptor, Serotonin, 5-HT2A; Receptor, Serotonin, 5-HT2C; Reproducibility of Results; Serotonin 5-HT1 Receptor Agonists; Serotonin 5-HT2 Receptor Agonists; Serotonin Agents

2009
Stimulation of medial prefrontal cortex serotonin 2C (5-HT(2C)) receptors attenuates cocaine-seeking behavior.
    Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2010, Volume: 35, Issue:10

    Topics: Aminopyridines; Animals; Cocaine-Related Disorders; Conditioning, Operant; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Extinction, Psychological; Indoles; Male; Prefrontal Cortex; Pyrazines; Rats; Rats, Sprague-Dawley; Receptor, Serotonin, 5-HT2C; Reinforcement, Psychology; Self Administration; Serotonin Antagonists; Serotonin Receptor Agonists

2010