6-bromo-8-methylaminoimidazo(1,2-a)pyrazine-2-carbonitrile has been researched along with Muscle Relaxation in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 10 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bompart, J; Bonnet, PA; Boucard, M; Chapat, JP; Laurent, F; Michel, A | 1 |
| Bonnet, PA; Boucard, M; Chapat, JP; Laurent, F; Michel, A | 1 |
| Bompart, J; Bonnet, PA; Boucard, M; Chapat, JP; Hadj-Kaddour, K; Laurent, F; Michel, A | 1 |
| Chilvers, ER; Macmillan, S; Patmore, L; Sheridan, RD | 1 |
| Advenier, C; Bakdach, H; Bonnet, PA; Cui, YY; Michel, A; Naline, E | 1 |
| Berto, L; Bonnet, PA; Cortijo, J; Michel, A; Morcillo, EJ; Navarrete, C; Sanz, C; Villagrasa, V | 1 |
| Buchheit, KH; Hofmann, A; Pfannkuche, HJ | 1 |
| Fozard, JR; Müller-Schweinitzer, E | 1 |
| Bonnet, PA; Chiu, P; Elliott, KR; Foster, RW; Isaac, LM; Laurent, F; Michel, A; Pocock, TM; Small, RC | 1 |
| Advenier, C; Cortijo, J; Dasí, F; Marín, N; Martinez-Losa, M; Morcillo, EJ; Pons, R | 1 |
10 other study(ies) available for 6-bromo-8-methylaminoimidazo(1,2-a)pyrazine-2-carbonitrile and Muscle Relaxation
| Article | Year |
|---|---|
[Effects of toxins, apamine, charybdotoxin and iberiotoxin on the relaxation of the smooth muscular fiber induced by imidazo(1,2-a)pyrazine derivative].
Topics: Animals; Apamin; Charybdotoxin; Guinea Pigs; Imidazoles; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Parasympatholytics; Peptides; Potassium Channels; Pyrazines; Scorpion Venoms; Trachea | 1993 |
Evaluation of the relaxant effects of SCA40, a novel charybdotoxin-sensitive potassium channel opener, in guinea-pig isolated trachealis.
Topics: Animals; Carbachol; Charybdotoxin; Glyburide; Guinea Pigs; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle Tonus; Potassium Channels; Potassium Chloride; Pyrazines; Scorpion Venoms; Trachea | 1993 |
Cardiovascular effects of SCA40, a novel potassium channel opener, in rats.
Topics: Animals; Aorta, Thoracic; Blood Pressure; Cardiotonic Agents; Cardiovascular System; Dose-Response Relationship, Drug; Drug Interactions; Heart Atria; Heart Rate; Imidazoles; Isoproterenol; Male; Muscle Relaxation; Muscle, Smooth, Vascular; Myocardial Contraction; Parasympatholytics; Potassium Channels; Propranolol; Pyrazines; Rats; Rats, Wistar | 1993 |
A comparison of the effects of SCA40, NS 004 and NS 1619 on large conductance Ca(2+)-activated K+ channels in bovine tracheal smooth muscle cells in culture.
Topics: Animals; Benzimidazoles; Calcium; Cattle; Cells, Cultured; Chlorophenols; Electric Conductivity; Imidazoles; In Vitro Techniques; Ion Channel Gating; Muscle Relaxation; Muscle, Smooth; Parasympatholytics; Potassium Channels; Pyrazines; Trachea | 1995 |
Effects of SCA40 on human bronchi and on guinea pig main bronchi in vitro. Comparison with cromakalim.
Topics: Acetylcholine; Animals; Benzopyrans; Bronchi; Bronchodilator Agents; Capsaicin; Charybdotoxin; Cromakalim; Electric Stimulation; Female; Glyburide; Guinea Pigs; Humans; Imidazoles; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Neurokinin A; Nitroprusside; Osmolar Concentration; Parasympatholytics; Potassium Channel Blockers; Potassium Channels; Pyrazines; Pyrroles; Tetraethylammonium; Tetraethylammonium Compounds | 1996 |
Effects of SCA40 on human isolated bronchus and human polymorphonuclear leukocytes: comparison with rolipram, SKF94120 and levcromakalim.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Anti-Inflammatory Agents, Non-Steroidal; Benzopyrans; Bronchi; Bronchodilator Agents; Calcium; Cardiotonic Agents; Cromakalim; Cyclic Nucleotide Phosphodiesterases, Type 3; Cyclic Nucleotide Phosphodiesterases, Type 4; Cyclic Nucleotide Phosphodiesterases, Type 5; Humans; Imidazoles; In Vitro Techniques; Leukocyte Elastase; Leukotriene B4; Muscle Relaxation; N-Formylmethionine Leucyl-Phenylalanine; Neutrophils; Phosphoric Diester Hydrolases; Pyrazines; Pyrroles; Pyrrolidinones; Rolipram; Superoxides | 1996 |
In vitro and in vivo effects of SCA40 on guinea pig airways.
Topics: Albuterol; Animals; Blood Pressure; Bombesin; Bronchoconstriction; Bronchodilator Agents; Guinea Pigs; Heart Rate; Histamine; Imidazoles; In Vitro Techniques; Male; Muscle Relaxation; Muscle, Smooth; Pyrazines; Respiratory Hypersensitivity; Trachea | 1997 |
SCA 40: studies of the relaxant effects on cryopreserved human airway and vascular smooth muscle.
Topics: Albuterol; Bronchi; Carbachol; Cryopreservation; Drug Interactions; Humans; Imidazoles; Muscle Relaxation; Muscle, Smooth, Vascular; Potassium; Pyrazines | 1997 |
Effects of SCA40 on bovine trachealis muscle and on cyclic nucleotide phosphodiesterases.
Topics: Animals; Bronchodilator Agents; Cattle; Cromakalim; Dose-Response Relationship, Drug; Electrophysiology; Glycoproteins; Imidazoles; Isoproterenol; Membrane Potentials; Muscle Relaxation; Parasympatholytics; Pyrazines; Rubidium; Trachea | 1997 |
Bronchodilator and anti-inflammatory activities of SCA40: studies in human isolated bronchus, human eosinophils, and in the guinea-pig in vivo.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antigens; Bronchi; Bronchial Hyperreactivity; Bronchodilator Agents; Eosinophils; Guinea Pigs; Humans; Imidazoles; In Vitro Techniques; Leukotriene C4; Muscle Relaxation; Muscle, Smooth; Pyrazines | 1997 |