6-anilino-5,8-quinolinedione has been researched along with Muscle Contraction in 20 studies
6-anilino-5,8-quinolinedione: structure given in first source; SRS-A & guanylate cyclase antagonist
6-anilino-5,8-quinolinedione : A quinolone that is quinoline-5,8-dione in which the hydrogen at position 6 is replaced by an anilino group.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Because cyclic GMP (cGMP) is a second messenger for nitric oxide (NO) inhibition of smooth muscle contraction, we rested the hypothesis that NO acts via cGMP in diaphragm." | 3.70 | Cyclic GMP is a second messenger by which nitric oxide inhibits diaphragm contraction. ( Abraham, RZ; Kobzik, L; Moody, MR; Reid, MB; Stamler, JS, 1998) |
| " BNP inhibited the contractile response produced by CCK-8 in a dose-response manner, with an IC50 value of 8." | 1.31 | Interaction between brain natriuretic peptide and atrial natriuretic peptide in caecal circular smooth muscle cells. ( Chijiiwa, Y; Motomura, Y; Nawata, H; Ochiai, T; Yasuda, O, 2000) |
| "Clonidine did not increase cGMP levels in vascular preparations with intact endothelia, in the presence or absence of LY83583." | 1.27 | Evidence that cGMP is the mediator of endothelium-dependent inhibition of contractile responses of rat arteries to alpha-adrenoceptor stimulation. ( Diamond, J; Harris, KH; MacLeod, KM; Ng, DD, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (10.00) | 18.7374 |
| 1990's | 13 (65.00) | 18.2507 |
| 2000's | 5 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tabet, F | 1 |
| Savoia, C | 1 |
| Schiffrin, EL | 1 |
| Touyz, RM | 1 |
| Guo, HS | 1 |
| Yang, YZ | 1 |
| Zou, Y | 1 |
| Xu, J | 1 |
| Cai, ZX | 1 |
| Qi, QH | 1 |
| Fleisch, JH | 1 |
| Haisch, KD | 1 |
| Spaethe, SM | 1 |
| Rinkema, LE | 1 |
| Cullinan, GJ | 1 |
| Schmidt, MJ | 1 |
| Marshall, WS | 1 |
| Wu, M | 1 |
| Pritchard, KA | 1 |
| Kaminski, PM | 1 |
| Fayngersh, RP | 1 |
| Hintze, TH | 1 |
| Wolin, MS | 1 |
| Harada, N | 2 |
| Chijiiwa, Y | 3 |
| Akiho, H | 1 |
| Okabe, H | 1 |
| Nawata, H | 3 |
| Coceani, F | 1 |
| Kelsey, L | 1 |
| Seidlitz, E | 1 |
| Abdullah, K | 1 |
| Cawley, T | 1 |
| Connolly, C | 1 |
| Ruiz, E | 1 |
| Docherty, JR | 1 |
| Ding, KH | 1 |
| Abdel-Latif, AA | 1 |
| Young, ME | 1 |
| Leighton, B | 1 |
| Andrade, FH | 1 |
| Reid, MB | 2 |
| Allen, DG | 1 |
| Westerblad, H | 1 |
| Clyman, RI | 1 |
| Waleh, N | 1 |
| Black, SM | 1 |
| Riemer, RK | 1 |
| Mauray, F | 1 |
| Chen, YQ | 1 |
| Maréchal, G | 1 |
| Beckers-Bleukx, G | 1 |
| Ahn, TY | 1 |
| Gómez-Coronado, D | 1 |
| Martínez, V | 1 |
| Cuevas, P | 1 |
| Goldstein, I | 1 |
| Sáenz de Tejada, I | 1 |
| Hernanz, R | 1 |
| Alonso, MJ | 1 |
| Baena, AB | 1 |
| Salaices, M | 1 |
| Alvarez, L | 1 |
| Castillo-Olivares, JL | 1 |
| Marín, J | 1 |
| Yasuda, O | 2 |
| Motomura, Y | 2 |
| Ochiai, T | 2 |
| Abraham, RZ | 1 |
| Kobzik, L | 1 |
| Moody, MR | 1 |
| Stamler, JS | 1 |
| Solovĭov, AI | 1 |
| Lehen'kyĭ, VV | 1 |
| Zelens'kyĭ, SM | 1 |
| Moĭbenko, OO | 1 |
| Stefanov, OV | 1 |
| Fleming, I | 1 |
| Julou-Schaeffer, G | 1 |
| Gray, GA | 1 |
| Parratt, JR | 1 |
| Stoclet, JC | 1 |
| MacLeod, KM | 1 |
| Ng, DD | 1 |
| Harris, KH | 1 |
| Diamond, J | 1 |
20 other studies available for 6-anilino-5,8-quinolinedione and Muscle Contraction
| Article | Year |
|---|---|
Differential calcium regulation by hydrogen peroxide and superoxide in vascular smooth muscle cells from spontaneously hypertensive rats.
Topics: Aminoquinolines; Animals; Calcium; Calcium Channels, L-Type; Calcium Channels, T-Type; Calcium Signa | 2004 |
Effects of dendroaspis natriuretic peptide on calcium-activated potassium current and its mechanism.
Topics: Aminoquinolines; Animals; Calcium; Calcium Channel Blockers; Dose-Response Relationship, Drug; Drug | 2008 |
Pharmacologic analysis of two novel inhibitors of leukotriene (slow reacting substance) release.
Topics: Aminoquinolines; Animals; Calcimycin; Cromolyn Sodium; Guinea Pigs; Histamine Release; Ileum; Lung; | 1984 |
Involvement of nitric oxide and nitrosothiols in relaxation of pulmonary arteries to peroxynitrite.
Topics: Aminoquinolines; Animals; Cattle; Free Radical Scavengers; Glutathione; In Vitro Techniques; Kinetic | 1994 |
Direct inhibitory effect of thyrotropin-releasing hormone on isolated cecal circular smooth muscle cells of guinea pig.
Topics: Aminoquinolines; Animals; Arginine; Carbachol; Cecum; Cell Size; Cyclic AMP; Cyclic GMP; Enzyme Inhi | 1996 |
Carbon monoxide-induced relaxation of the ductus arteriosus in the lamb: evidence against the prime role of guanylyl cyclase.
Topics: Aminoquinolines; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbon Monoxide; Cyclic GMP; Cyto | 1996 |
Comparison of the effects of nitric oxide synthase inhibition and guanylate cyclase inhibition on vascular contraction in vitro and in vivo in the rat.
Topics: Acetylcholine; Aminoquinolines; Animals; Aorta; Endothelium, Vascular; Enzyme Inhibitors; Guanylate | 1997 |
Actions of C-type natriuretic peptide and sodium nitroprusside on carbachol-stimulated inositol phosphate formation and contraction in ciliary and iris sphincter smooth muscles.
Topics: Aminoquinolines; Animals; Atrial Natriuretic Factor; Carbachol; Cats; Cattle; Ciliary Body; Cyclic A | 1997 |
Fuel oxidation in skeletal muscle is increased by nitric oxide/cGMP--evidence for involvement of cGMP-dependent protein kinase.
Topics: Aminoquinolines; Animals; Cyclic GMP; Cyclic GMP-Dependent Protein Kinases; Enzyme Inhibitors; Gluco | 1998 |
Effect of nitric oxide on single skeletal muscle fibres from the mouse.
Topics: Acetylcysteine; Aminoquinolines; Animals; Calcium; Enzyme Inhibitors; Guanylate Cyclase; In Vitro Te | 1998 |
Regulation of ductus arteriosus patency by nitric oxide in fetal lambs: the role of gestation, oxygen tension, and vasa vasorum.
Topics: Aminoquinolines; Animals; Aorta; Calcimycin; Ductus Arteriosus; Ductus Arteriosus, Patent; Enzyme In | 1998 |
Effect of nitric oxide on the maximal velocity of shortening of a mouse skeletal muscle.
Topics: 1-Methyl-3-isobutylxanthine; Aminoquinolines; Animals; Biomechanical Phenomena; Cyclic GMP; Enzyme I | 1998 |
Enhanced contractility of rabbit corpus cavernosum smooth muscle by oxidized low density lipoproteins.
Topics: Aminoquinolines; Animals; Butylated Hydroxytoluene; Copper; Dose-Response Relationship, Drug; Endoth | 1999 |
Mechanisms involved in relaxation induced by exogenous nitric oxide in pig coronary arteries.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Aminoquinolines; Animals; Corona | 1999 |
Interaction between brain natriuretic peptide and atrial natriuretic peptide in caecal circular smooth muscle cells.
Topics: Aminoquinolines; Animals; Atrial Natriuretic Factor; Binding Sites; Cecum; Cyclic AMP; Guinea Pigs; | 2000 |
Cyclic GMP is a second messenger by which nitric oxide inhibits diaphragm contraction.
Topics: Aminoquinolines; Animals; Cyclic GMP; Diaphragm; Dipyridamole; Enzyme Inhibitors; Guanylate Cyclase; | 1998 |
Direct inhibitory effect of adrenomedullin, calcitonin gene-related peptide, calcitonin, and amylin on cholecystokinin-induced contraction of guinea-pig isolated caecal circular smooth muscle cells.
Topics: Adrenomedullin; Aminoquinolines; Amyloid; Animals; Calcitonin; Calcitonin Gene-Related Peptide; Chol | 2001 |
[cGMP-independent effect of nitric oxide on contractility and intracellular calcium level of rat tail artery vascular smooth muscles].
Topics: Aminoquinolines; Animals; Arteries; Calcium; Cyclic GMP; Enzyme Inhibitors; Guanylate Cyclase; Male; | 2001 |
Evidence that an L-arginine/nitric oxide dependent elevation of tissue cyclic GMP content is involved in depression of vascular reactivity by endotoxin.
Topics: Aminoquinolines; Animals; Arginine; Cyclic GMP; Endotoxins; Enzyme Activation; Guanylate Cyclase; In | 1991 |
Evidence that cGMP is the mediator of endothelium-dependent inhibition of contractile responses of rat arteries to alpha-adrenoceptor stimulation.
Topics: Acetylcholine; Adrenergic alpha-Agonists; Aminoquinolines; Animals; Aorta; Clonidine; Cyclic GMP; En | 1987 |