6-anilino-5,8-quinolinedione has been researched along with Huntington Disease in 1 studies
6-anilino-5,8-quinolinedione: structure given in first source; SRS-A & guanylate cyclase antagonist
6-anilino-5,8-quinolinedione : A quinolone that is quinoline-5,8-dione in which the hydrogen at position 6 is replaced by an anilino group.
Huntington Disease: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sarkar, S | 1 |
| Perlstein, EO | 1 |
| Imarisio, S | 1 |
| Pineau, S | 1 |
| Cordenier, A | 1 |
| Maglathlin, RL | 1 |
| Webster, JA | 1 |
| Lewis, TA | 1 |
| O'Kane, CJ | 1 |
| Schreiber, SL | 1 |
| Rubinsztein, DC | 1 |
1 other study available for 6-anilino-5,8-quinolinedione and Huntington Disease
| Article | Year |
|---|---|
Small molecules enhance autophagy and reduce toxicity in Huntington's disease models.
Topics: Animals; Autophagy; Huntington Disease; Mammals; Models, Biological; Neuroprotective Agents; Sacchar | 2007 |