6-anilino-5,8-quinolinedione has been researched along with Cardiomegaly in 1 studies
6-anilino-5,8-quinolinedione: structure given in first source; SRS-A & guanylate cyclase antagonist
6-anilino-5,8-quinolinedione : A quinolone that is quinoline-5,8-dione in which the hydrogen at position 6 is replaced by an anilino group.
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We tested the hypothesis that a reduction in myocardial cyclic GMP would increase myocardial O2 consumption and that renal hypertension (One Kidney-One Clip, 1K1C)-induced cardiac hypertrophy would change this relationship." | 7.69 | Reduced myocardial cyclic GMP increases myocardial O2 consumption in control but not renal hypertension-induced cardiac hypertrophy. ( Sadoff, JD; Scholz, PM; Tse, J; Weiss, HR, 1997) |
| "We tested the hypothesis that a reduction in myocardial cyclic GMP would increase myocardial O2 consumption and that renal hypertension (One Kidney-One Clip, 1K1C)-induced cardiac hypertrophy would change this relationship." | 3.69 | Reduced myocardial cyclic GMP increases myocardial O2 consumption in control but not renal hypertension-induced cardiac hypertrophy. ( Sadoff, JD; Scholz, PM; Tse, J; Weiss, HR, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sadoff, JD | 1 |
| Scholz, PM | 1 |
| Tse, J | 1 |
| Weiss, HR | 1 |
1 other study available for 6-anilino-5,8-quinolinedione and Cardiomegaly
| Article | Year |
|---|---|
Reduced myocardial cyclic GMP increases myocardial O2 consumption in control but not renal hypertension-induced cardiac hypertrophy.
Topics: Aminoquinolines; Analysis of Variance; Animals; Cardiomegaly; Coronary Circulation; Cyclic GMP; Enzy | 1997 |