5-nitro-2-(3-phenylpropylamino)benzoic acid has been researched along with Cystic Fibrosis of Pancreas in 11 studies
5-nitro-2-(3-phenylpropylamino)benzoic acid: structure given in first source; chloride channel antagonist
| Excerpt | Relevance | Reference |
|---|---|---|
| "VX-770 (Ivacaftor) has been approved for clinical usage in cystic fibrosis patients with several CFTR mutations." | 3.83 | Potentiators exert distinct effects on human, murine, and Xenopus CFTR. ( Cui, G; Imhoff, BR; Infield, DT; Khazanov, N; McCarty, NA; Senderowitz, H; Stauffer, BB, 2016) |
| "Cystic fibrosis is caused by mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) Cl- channel, which mediates transepithelial Cl- transport in a variety of epithelia, including airway, intestine, pancreas, and sweat duct." | 1.30 | Exocytosis is not involved in activation of Cl- secretion via CFTR in Calu-3 airway epithelial cells. ( Loffing, J; McCoy, D; Moyer, BD; Stanton, BA, 1998) |
| "Cystic fibrosis has been characterized as a defect in the regulation of cyclic AMP-dependent transepithelial chloride transport." | 1.29 | Cyclic AMP-related and cation-affected human platelet chloride transport regulation. ( Agam, G; Aviram, M; Livne, AA; Rothstein, A; Zilberman-Kaufman, M, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (9.09) | 18.7374 |
| 1990's | 4 (36.36) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 3 (27.27) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jeong, JH | 1 |
| Joo, NS | 1 |
| Hwang, PH | 1 |
| Wine, JJ | 1 |
| Stott, JB | 1 |
| deCourcey, F | 1 |
| Ennis, M | 1 |
| Zholos, AV | 1 |
| Cui, G | 1 |
| Khazanov, N | 1 |
| Stauffer, BB | 1 |
| Infield, DT | 1 |
| Imhoff, BR | 1 |
| Senderowitz, H | 1 |
| McCarty, NA | 1 |
| Cho, WK | 1 |
| Siegrist, VJ | 1 |
| Zinzow, W | 1 |
| Agam, G | 1 |
| Aviram, M | 1 |
| Zilberman-Kaufman, M | 1 |
| Rothstein, A | 1 |
| Livne, AA | 1 |
| Jiang, C | 1 |
| Finkbeiner, WE | 1 |
| Widdicombe, JH | 1 |
| Miller, SS | 1 |
| Loffing, J | 1 |
| Moyer, BD | 1 |
| McCoy, D | 1 |
| Stanton, BA | 1 |
| Rückes-Nilges, C | 1 |
| Weber, U | 1 |
| Lindemann, H | 1 |
| Münker, G | 1 |
| Clauss, W | 1 |
| Weber, WM | 1 |
| Gabriel, SE | 1 |
| Makhlina, M | 1 |
| Martsen, E | 1 |
| Thomas, EJ | 1 |
| Lethem, MI | 1 |
| Boucher, RC | 1 |
| Gyömörey, K | 1 |
| Garami, E | 1 |
| Galley, K | 1 |
| Rommens, JM | 1 |
| Bear, CE | 1 |
| Kunzelmann, K | 1 |
| Pavenstädt, H | 1 |
| Greger, R | 1 |
11 other studies available for 5-nitro-2-(3-phenylpropylamino)benzoic acid and Cystic Fibrosis of Pancreas
| Article | Year |
|---|---|
Mucociliary clearance and submucosal gland secretion in the ex vivo ferret trachea.
Topics: Analgesics, Non-Narcotic; Angiogenesis Inhibitors; Animals; Bronchodilator Agents; Bumetanide; Calci | 2014 |
Functional and pharmacological characterization of volume-regulated anion channels in human normal and cystic fibrosis bronchial and nasal epithelial cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Bronchi; Cell Line; Chloride Channels; Cyclopentan | 2014 |
Potentiators exert distinct effects on human, murine, and Xenopus CFTR.
Topics: Amino Acid Sequence; Aminophenols; Animals; Cells, Cultured; Chloride Channel Agonists; Cystic Fibro | 2016 |
Impaired regulatory volume decrease in freshly isolated cholangiocytes from cystic fibrosis mice: implications for cystic fibrosis transmembrane conductance regulator effect on potassium conductance.
Topics: 1-Methyl-3-isobutylxanthine; Angiogenesis Inhibitors; Animals; Bile Ducts; Buffers; Colforsin; Cycli | 2004 |
Cyclic AMP-related and cation-affected human platelet chloride transport regulation.
Topics: Adolescent; Alprostadil; Blood Platelets; Cations; Child; Child, Preschool; Chloride Channels; Cycli | 1995 |
Fluid transport across cultures of human tracheal glands is altered in cystic fibrosis.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Amiloride; Biological Transport, Active; Body Flui | 1997 |
Exocytosis is not involved in activation of Cl- secretion via CFTR in Calu-3 airway epithelial cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Acetazolamide; Amiloride; Cell Membrane; Chloride | 1998 |
Minor role of Cl- secretion in non-cystic fibrosis and cystic fibrosis human nasal epithelium.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Adenosine Triphosphate; Amiloride; Calcium Channel | 1999 |
Permeabilization via the P2X7 purinoreceptor reveals the presence of a Ca2+-activated Cl- conductance in the apical membrane of murine tracheal epithelial cells.
Topics: 4,4'-Diisothiocyanostilbene-2,2'-Disulfonic Acid; Animals; Bromine; Calcium; Calcium Channel Blocker | 2000 |
Non-CFTR chloride channels likely contribute to secretion in the murine small intestine.
Topics: Angiogenesis Inhibitors; Animals; Biological Transport; Calcium Signaling; Chloride Channels; Chlori | 2001 |
Properties and regulation of chloride channels in cystic fibrosis and normal airway cells.
Topics: Calcium; Cell Membrane; Cells, Cultured; Chloride Channels; Chlorides; Cystic Fibrosis; Electric Con | 1989 |