5-nitro-2-(3-phenylpropylamino)benzoic acid has been researched along with Cataract in 4 studies
5-nitro-2-(3-phenylpropylamino)benzoic acid: structure given in first source; chloride channel antagonist
Cataract: Partial or complete opacity on or in the lens or capsule of one or both eyes, impairing vision or causing blindness. The many kinds of cataract are classified by their morphology (size, shape, location) or etiology (cause and time of occurrence). (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Cataracts have a high incidence and prevalence rate worldwide, and they are the leading cause of blindness." | 1.62 | 5‑Nitro‑2‑(3‑phenylpropylamino) benzoic acid induces apoptosis of human lens epithelial cells via reactive oxygen species and endoplasmic reticulum stress through the mitochondrial apoptosis pathway. ( Li, K; Li, Y; Liu, X; Niu, L; Sun, Y; Wang, Y; Zhao, J; Zheng, Y, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (75.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (25.00) | 2.80 |
| Authors | Studies |
|---|---|
| Niu, L | 1 |
| Liu, X | 1 |
| Zhao, J | 1 |
| Wang, Y | 1 |
| Li, Y | 1 |
| Li, K | 1 |
| Sun, Y | 1 |
| Zheng, Y | 1 |
| Zhang, JJ | 1 |
| Jacob, TJ | 1 |
| Wang, LF | 1 |
| Dhir, P | 1 |
| Bhatnagar, A | 1 |
| Srivastava, SK | 1 |
| Tunstall, MJ | 1 |
| Eckert, R | 1 |
| Donaldson, P | 1 |
| Kistler, J | 1 |
4 other studies available for 5-nitro-2-(3-phenylpropylamino)benzoic acid and Cataract
| Article | Year |
|---|---|
5‑Nitro‑2‑(3‑phenylpropylamino) benzoic acid induces apoptosis of human lens epithelial cells via reactive oxygen species and endoplasmic reticulum stress through the mitochondrial apoptosis pathway.
Topics: Apoptosis; Caspase 3; Cataract; Cell Survival; Cells, Cultured; Chloride Channels; Endoplasmic Retic | 2021 |
Volume regulation in the bovine lens and cataract. The involvement of chloride channels.
Topics: Animals; Cataract; Cattle; Chloride Channels; Estrogen Antagonists; In Vitro Techniques; Ion Channel | 1996 |
Contribution of osmotic changes to disintegrative globulization of single cortical fibers isolated from rat lens.
Topics: Animals; Calcium; Cataract; Cells, Cultured; Chloride Channels; Colforsin; Edetic Acid; HEPES; Hypot | 1997 |
Localised fibre cell swelling characteristic of diabetic cataract can be induced in normal rat lens using the chloride channel blocker 5-nitro-2-(3-phenylpropylamino) benzoic acid.
Topics: Animals; Aqueous Humor; Cataract; Chloride Channels; Corneal Edema; Diabetes Mellitus, Experimental; | 1999 |