5-nitro-2-(3-phenylpropylamino)benzoic acid has been researched along with Cardiac Hypertrophy in 2 studies
5-nitro-2-(3-phenylpropylamino)benzoic acid: structure given in first source; chloride channel antagonist
Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Protocatechuic acid (3,4-dihydroxybenzoic acid) prevents oxidative stress, inflammation and cardiac hypertrophy." | 8.31 | Protocatechuic acid prevents isoproterenol-induced heart failure in mice by downregulating kynurenine-3-monooxygenase. ( Bai, L; Han, X; He, X; Jeon, MJ; Jeong, MH; Jeong, SM; Kee, HJ; Kee, SJ; Kim, SH; Zhou, H, 2023) |
| "Protocatechuic acid (3,4-dihydroxybenzoic acid) prevents oxidative stress, inflammation and cardiac hypertrophy." | 4.31 | Protocatechuic acid prevents isoproterenol-induced heart failure in mice by downregulating kynurenine-3-monooxygenase. ( Bai, L; Han, X; He, X; Jeon, MJ; Jeong, MH; Jeong, SM; Kee, HJ; Kee, SJ; Kim, SH; Zhou, H, 2023) |
| "PE treatment induced the expression of cardiac hypertrophy markers, including natriuretic peptide A (Nppa), natriuretic peptide B (Nppb), and myosin heavy chain 7 (Myh7), in a time-dependent manner in NRVMs." | 1.91 | Dose-dependent Effects of PRC2 and HDAC Inhibitors on Cardiomyocyte Hypertrophy Induced by Phenylephrine. ( Chen, W; Fang, Y; Guo, N; Guo, Q; Lv, J; Wang, Z; Zeng, S; Zhao, Z, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhao, Z | 1 |
| Lv, J | 1 |
| Guo, N | 1 |
| Guo, Q | 1 |
| Zeng, S | 1 |
| Fang, Y | 1 |
| Chen, W | 1 |
| Wang, Z | 1 |
| Bai, L | 1 |
| Han, X | 1 |
| Kee, HJ | 1 |
| He, X | 1 |
| Kim, SH | 1 |
| Jeon, MJ | 1 |
| Zhou, H | 1 |
| Jeong, SM | 1 |
| Kee, SJ | 1 |
| Jeong, MH | 1 |
2 other studies available for 5-nitro-2-(3-phenylpropylamino)benzoic acid and Cardiac Hypertrophy
| Article | Year |
|---|---|
Dose-dependent Effects of PRC2 and HDAC Inhibitors on Cardiomyocyte Hypertrophy Induced by Phenylephrine.
Topics: Animals; Cardiomegaly; Histone Deacetylase Inhibitors; Histones; Myocytes, Cardiac; Natriuretic Pept | 2023 |
Protocatechuic acid prevents isoproterenol-induced heart failure in mice by downregulating kynurenine-3-monooxygenase.
Topics: Animals; Cardiomegaly; Heart Failure; Isoproterenol; Kynurenine; Kynurenine 3-Monooxygenase; Mice; M | 2023 |