Compounds > 5-methylcytosine
Page last updated: 2024-08-24

5-methylcytosine and Pregnancy

5-methylcytosine has been researched along with Pregnancy in 69 studies

Research

Studies (69)

TimeframeStudies, this research(%)All Research%
pre-19909 (13.04)18.7374
1990's4 (5.80)18.2507
2000's6 (8.70)29.6817
2010's38 (55.07)24.3611
2020's12 (17.39)2.80

Authors

AuthorsStudies
Goetzinger, KR; Harman, C; Ni, J; Reece, EA; Shen, WB; Wang, B; Yang, P; Yao, R1
Bukowska, B; Sicińska, P1
Alisch, RS; Chen, K; Keleş, S; Madrid, A; Papale, LA; Sak, L; Zhang, Q1
Bian, J; Hou, J; Liu, K; Qi, Q; Wang, Q; Yu, Z1
Arman, B; Fullston, T; McPherson, N; Penn, A; Zander-Fox, D1
Caniçais, C; Chuva de Sousa Lopes, SM; Dória, S; Marques, CJ; Vasconcelos, S1
Li, H; Tong, J; Zhang, C1
Chorley, BN; Corton, JC; Gunewardena, S; Klaassen, CD; Liu, J; Yue Cui, J1
Fang, Q; Zhang, Y; Zheng, D; Zhong, M1
Gibas, P; Gordevičius, J; Kriukienė, E; Krjutškov, K; Kvederavičiūtė, K; Narmontė, M; Paluoja, P; Salumets, A; Tomkutė, V1
Ito, T; Kubiura-Ichimaru, M; Lefebvre, L; Tada, M1
Baranov, VS; Chiryaeva, OG; Dudkina, VS; Efimova, OA; Krapivin, MI; Pendina, AA; Petrova, LI; Smirnova, AA; Talantova, OE; Tikhonov, AV1
Chen, M; Dasgupta, C; Han, L; Hu, XQ; Huang, X; Xiao, D; Xu, Z; Yang, S; Zhang, L1
Öztürk, H; Öztürk, NC; Resendiz, M; Zhou, FC1
Esteller, M; Hernandez Mora, JR; Iglesias-Platas, I; Monk, D; Moran, S; Petazzi, P; Sanchez-Delgado, M1
Liu, L; Mitsuya, K; Myatt, L; Parker, AN; Ruan, J; Vissers, MCM1
Cindrova-Davies, T; Kieckbusch, J; Krzak, AM; Padmanabhan, N; Rakoczy, J; Watson, ED1
Bogo, MR; Crippa, JAS; da Silva, VK; de Freitas, BS; Dornelles, VC; Hallak, JE; Kist, LW; Schröder, N; Silva, MC; Streck, EL; Zuardi, AW1
Deng, R; Han, C; Liu, J; Luo, Y; Mao, T; Meng, P; Quan, F; Wei, B; Zhang, Q; Zhang, Y; Zhao, L1
Chen, SL; Chen, X; Chen, XL; Liu, YD; Lu, S; Wu, AH; Yang, DY1
Chen, D; Jin, J; Li, X; Liu, A; Luo, Z; Wu, Y; Xie, F; Zhang, F; Zhang, S1
Bjork, F; Harris, SM; Hassan, I; Kumar, A; Lash, LH; Loch-Caruso, R1
Baranov, VS; Efimova, OA; Glotov, OS; Kopat, VV; Krapivin, MI; Navodnikova, PM; Pendina, AA; Petrovskaia-Kaminskaia, AV; Talantova, OE; Tikhonov, AV1
Adeli, S; Phillippe, M; Sawyer, MR1
An, X; Cheng, H; Jiang, Y; Li, Z; Ma, X; Tang, B; Zhai, Y; Zhang, J; Zhang, S; Zhang, X1
Cao, Z; Chen, Z; Gao, D; Khan, IM; Luo, L; Tong, X; Wang, Y; Xu, T; Zhang, D; Zhang, L; Zhang, M; Zhang, Y1
Buchholz, F; Calegari, F; Noack, F; Pataskar, A; Schneider, M; Tiwari, VK1
Bianco-Miotto, T; François, M; Jankovic-Karasoulos, T; Leifert, WR; McAninch, D; McCullough, D; Roberts, CT; Wilson, RL1
Huang, Y; Jin, L; Lin, S; Ren, A; Wang, L1
Doria, S; Marques, CJ; Ramalho, C; Vasconcelos, S1
Chen, Y; Oztürk, NC; Resendiz, M; Zhou, FC1
Achterfeldt, S; Godschalk, RW; Gorniak, JP; Halley-Hogg, KJ; Langie, SA; Mathers, JC; McKay, JA; Oxley, D; van Schooten, FJ1
Ashley-Koch, A; DeBussycher, T; Fry, RC; Laine, JE; Lynn Miranda, M; Rager, JE; Rojas, D; Sanders, AP; Smeester, L; Swamy, GK; Wright, FA; Wu, MC; Zhou, YH1
Dhimolea, E; Murray, TJ; Settles, ML; Shioda, T; Sonnenschein, C; Soto, AM; Treitman, JD; Wadia, PR1
Bailey, KA; Drobná, Z; Fry, RC; García-Vargas, G; Rager, JE; Rojas, D; Rubio-Andrade, M; Smeester, L; Stýblo, M1
Das, SK; Gao, F1
Inoue, A; Matoba, S; Shen, L; Zhang, Y1
Hatanaka, Y; Inoue, H; Inoue, K; Kamimura, S; Kurotaki, YK; Ogonuki, N; Ogura, A; Oikawa, M1
Drake, AJ; Khulan, B; Menon, G; Piyasena, C; Reynolds, RM; Seckl, JR1
Cheng, H; Kong, L; Lan, F; Li, X; Lv, R; Zhu, L1
Akiyama, T; Nakayama, KI; Tsukada, Y1
Chen, J; Chen, L; Dai, Q; Gao, Q; He, C; Jin, P; Li, L; Lin, L; Song, MM; Sun, M; Tao, J; Wei, B; Xu, Z; Yao, B; Zhou, X1
Armstrong, DA; Christensen, BC; Green, BB; Guerin, DJ; Houseman, EA; Johnson, KC; Marsit, CJ1
Dwi Putra, SE; Hocher, B; Kleuser, B; Neuber, C; Pfab, T; Reichetzeder, C; Slowinski, T1
Devlieger, R; Duca, RC; Freson, K; Godderis, L; Huybrechts, I; Koppen, G; Pauwels, S; Straetmans, D; Van Herck, E1
Chow, PH; Lee, KH; O, WS; Poon, HK; Wong, CL1
Hemberger, M1
Chen, Y; Love, A; Zhou, FC1
Hata, K; Hayakawa, K; Nakabayashi, K; Nakanishi, MO; Shiota, K; Tanaka, S1
Rugg-Gunn, PJ1
Chouliaras, L; Delbroek, L; Prickaerts, J; Rostamian, S; Rutten, BP; Sierksma, AS; Steinbusch, HW; van den Hove, DL1
Intano, GW; Kazianis, S; Li, HY; Walter, CA; Walter, RB1
Bartolomei, MS; Bishop, MD; Cezar, GG; Eilertsen, KJ; First, NL; Forsberg, EJ1
Benchaib, M; Braun, V; Durand, P; Guérin, JF; Lornage, J; Niveleau, A; Ressnikof, D1
Elmlinger, M; Hiendleder, S; Klempt, M; Lyko, F; Mund, C; Reichenbach, HD; Schmitz, OJ; Stojkovic, M; Wenigerkind, H; Weppert, M; Wirtz, M; Wolf, E1
Ajina, M; Benchaïb, M; Braun, V; Guérin, JF; Niveleau, A1
Hjelle, BL; Phillips, JA; Seeburg, PH1
Ehrlich, M; Gama-Sosa, MA; Gehrke, CW; Kuo, KC; Oxenhandler, R; Slagel, VA; Trewyn, RW1
Breznik, T; Butel, JS; Cohen, JC; Ehrlich, M; Gama-Sosa, M; Gehrke, CW; Medina, D; Traina-Dorge, V1
Ehrlich, M; Gama-Sosa, MA; Gehrke, CW; Kuo, KC; Wang, RY1
Grahn, H; Kröger, H; Wohlert, H1
Ehrlich, M; Gama-Sosa, MA; Gehrke, C; Huang, LH; Kuo, KC; McCune, RA; Midgett, RM1
Romanov, GA; Vanyushin, BF1
Aurias, A; Fischer, A; Jeanpierre, M; Ledeist, F; Prieur, M; Turleau, C; Viegas-Pequignot, E1
Bourc'his, D; Gomes, DM; Niveleau, A; Pàldi, A; Plachot, M; Rougier, N; Viegas-Péquignot, E1
Cooney, CA; Kodell, RL; Moore, SR; Wolff, GL1
Garro, AJ; Lieber, CS; Lima, V; McBeth, DL1
Bou, M; Hoshina, M; Mochizuki, M1
Attinà, M; Cacace, F; Caiafa, P; Mastrantonio, S; Rispoli, M; Strom, R1

Reviews

6 review(s) available for 5-methylcytosine and Pregnancy

ArticleYear
Influence of Benzo(a)pyrene on Different Epigenetic Processes.
    International journal of molecular sciences, 2021, Dec-15, Volume: 22, Issue:24

    Topics: 5-Methylcytosine; Animals; Benzo(a)pyrene; Biotin; Carcinogenesis; DNA Methylation; Epigenesis, Genetic; Epigenomics; Female; Histone Deacetylases; Humans; Pregnancy; Prenatal Exposure Delayed Effects

2021
The role of DNA hydroxymethylation and TET enzymes in placental development and pregnancy outcome.
    Clinical epigenetics, 2023, 04-25, Volume: 15, Issue:1

    Topics: 5-Methylcytosine; Abortion, Spontaneous; Animals; DNA; DNA Methylation; Female; Humans; Mammals; Mice; Placenta; Placentation; Pregnancy; Pregnancy Outcome

2023
Epigenetic medicine and fetal alcohol spectrum disorders.
    Epigenomics, 2013, Volume: 5, Issue:1

    Topics: 5-Methylcytosine; Cell Differentiation; Cytosine; DNA Methylation; Embryonic Development; Epigenesis, Genetic; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Gene Expression Regulation; Histones; Humans; Pregnancy

2013
Epigenetic regulations through DNA methylation and hydroxymethylation: clues for early pregnancy in decidualization.
    Biomolecular concepts, 2014, Volume: 5, Issue:2

    Topics: 5-Methylcytosine; Animals; Chromatin; Cytosine; Decidua; DNA Methylation; Embryo Implantation; Epigenesis, Genetic; Female; Gene Expression Regulation; Histones; Humans; Pregnancy; Protein Processing, Post-Translational

2014
Genetic-epigenetic intersection in trophoblast differentiation: implications for extraembryonic tissue function.
    Epigenetics, 2010, Jan-01, Volume: 5, Issue:1

    Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cytosine; DNA Methylation; Embryonic Stem Cells; Epigenesis, Genetic; Female; Gene Expression Regulation; Humans; Models, Biological; Models, Genetic; Placenta; Plants; Pregnancy; Stem Cells; Trophoblasts

2010
Epigenetic features of the mouse trophoblast.
    Reproductive biomedicine online, 2012, Volume: 25, Issue:1

    Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; Epigenesis, Genetic; Female; Fetal Growth Retardation; Gene Expression Regulation, Developmental; Histones; Mice; Models, Animal; Pregnancy; Pregnancy Complications; Trophoblasts

2012

Other Studies

63 other study(ies) available for 5-methylcytosine and Pregnancy

ArticleYear
Maternal obesity increases DNA methylation and decreases RNA methylation in the human placenta.
    Reproductive toxicology (Elmsford, N.Y.), 2022, Volume: 107

    Topics: 5-Methylcytosine; Adenosine; DNA Methylation; Female; Humans; Methyltransferases; Obesity, Maternal; Placenta; Pregnancy; RNA

2022
Gene by environment interaction mouse model reveals a functional role for 5-hydroxymethylcytosine in neurodevelopmental disorders.
    Genome research, 2022, Volume: 32, Issue:2

    Topics: 5-Methylcytosine; Animals; DNA Methylation; Epigenesis, Genetic; Female; Gene-Environment Interaction; Membrane Proteins; Mice; Nerve Tissue Proteins; Neurodevelopmental Disorders; Pregnancy

2022
Early Expression of Tet1 and Tet2 in Mouse Zygotes Altered DNA Methylation Status and Affected Embryonic Development.
    International journal of molecular sciences, 2022, Jul-31, Volume: 23, Issue:15

    Topics: 5-Methylcytosine; Animals; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Embryonic Development; Female; Mammals; Mice; Pregnancy; Proto-Oncogene Proteins; Zygote

2022
Maternal high-fat diet changes DNA methylation in the early embryo by disrupting the TCA cycle intermediary alpha ketoglutarate.
    Reproduction (Cambridge, England), 2023, 04-01, Volume: 165, Issue:4

    Topics: 5-Methylcytosine; Animals; Cytosine; Diet, High-Fat; DNA Methylation; Female; Humans; Ketoglutaric Acids; Mice; Obesity, Maternal; Pregnancy; Zygote

2023
Altered 5-methylcytosine modification of mRNA is involved in the pathogenesis of pre-eclampsia.
    Journal of cellular biochemistry, 2023, Volume: 124, Issue:11

    Topics: 5-Methylcytosine; Female; Humans; Pre-Eclampsia; Pregnancy; Reproducibility of Results; RNA, Messenger; Signal Transduction

2023
Transplacental arsenic exposure produced 5-methylcytosine methylation changes and aberrant microRNA expressions in livers of male fetal mice.
    Toxicology, 2020, 04-15, Volume: 435

    Topics: 5-Methylcytosine; Animals; Arsenites; Cell Transformation, Neoplastic; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Developmental; Gene Expression Regulation, Neoplastic; Gestational Age; Liver; Liver Neoplasms; Male; Maternal Exposure; Mice, Inbred C3H; MicroRNAs; Pregnancy; Sodium Compounds

2020
Aberrant hydroxymethylation of
    Epigenetics, 2020, Volume: 15, Issue:8

    Topics: 5-Methylcytosine; Adult; Angiopoietin-Like Protein 4; Apoptosis; Cell Hypoxia; Cell Line; Cell Movement; DNA Methylation; Female; Fetal Growth Retardation; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Placenta; Pregnancy; Pregnancy, Twin; Promoter Regions, Genetic; Trophoblasts

2020
Identification of fetal unmodified and 5-hydroxymethylated CG sites in maternal cell-free DNA for non-invasive prenatal testing.
    Clinical epigenetics, 2020, 10-20, Volume: 12, Issue:1

    Topics: 5-Methylcytosine; Adult; Cell-Free Nucleic Acids; DNA Methylation; Down Syndrome; Epigenomics; Female; Fetal Diseases; Fetus; Genetic Testing; High-Throughput Nucleotide Sequencing; Humans; Male; Placenta; Pregnancy; Prenatal Diagnosis; Sensitivity and Specificity; Sequence Analysis, DNA; Trisomy

2020
Cyclic DNA remethylation following active demethylation at euchromatic regions in mouse embryonic stem cells.
    Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology, 2021, Volume: 29, Issue:2

    Topics: 5-Methylcytosine; Animals; Demethylation; DNA; DNA Methylation; Embryonic Development; Female; Mice; Mouse Embryonic Stem Cells; Pregnancy

2021
Telomere Length in Chromosomally Normal and Abnormal Miscarriages and Ongoing Pregnancies and Its Association with 5-hydroxymethylcytosine Patterns.
    International journal of molecular sciences, 2021, Jun-21, Volume: 22, Issue:12

    Topics: 5-Methylcytosine; Abortion, Spontaneous; Case-Control Studies; Chorion; DNA Methylation; Female; Humans; Lymphocytes; Pregnancy; Pregnancy Trimester, First; Telomere; Telomere Homeostasis; Trophoblasts

2021
Pregnancy Reprograms Large-Conductance Ca
    Hypertension (Dallas, Tex. : 1979), 2017, Volume: 69, Issue:6

    Topics: 5-Methylcytosine; Analysis of Variance; Animals; Blotting, Western; Dioxygenases; Estradiol; Estrogens; Female; Ion Transport; Methylation; Potassium Channels, Calcium-Activated; Pregnancy; Pregnancy, Animal; Protein Kinase C; Real-Time Polymerase Chain Reaction; Sheep; Tissue and Organ Harvesting; Up-Regulation; Uterine Artery

2017
DNA Methylation program in normal and alcohol-induced thinning cortex.
    Alcohol (Fayetteville, N.Y.), 2017, Volume: 60

    Topics: 5-Methylcytosine; Alcohol Drinking; Animals; DNA Methylation; Epigenesis, Genetic; Ethanol; Female; Fetal Alcohol Spectrum Disorders; Genotype; Gestational Age; Maternal Exposure; Mice, Inbred C57BL; Neocortex; Neurogenesis; Phenotype; Pregnancy

2017
Profiling of oxBS-450K 5-hydroxymethylcytosine in human placenta and brain reveals enrichment at imprinted loci.
    Epigenetics, 2018, Volume: 13, Issue:2

    Topics: 5-Methylcytosine; Brain; DNA Methylation; Female; Genetic Loci; Genomic Imprinting; Humans; Placenta; Pregnancy; snRNP Core Proteins; Ubiquitin-Protein Ligases

2018
Alterations in the placental methylome with maternal obesity and evidence for metabolic regulation.
    PloS one, 2017, Volume: 12, Issue:10

    Topics: 5-Methylcytosine; Adiposity; Body Mass Index; DNA Methylation; Epigenesis, Genetic; Female; Genome, Human; Humans; Metabolome; Multigene Family; Obesity; Placenta; Pregnancy; Thinness

2017
Dynamic expression of TET1, TET2, and TET3 dioxygenases in mouse and human placentas throughout gestation.
    Placenta, 2017, Volume: 59

    Topics: 5-Methylcytosine; Animals; Dioxygenases; DNA-Binding Proteins; Female; Humans; Mice; Mixed Function Oxygenases; Placenta; Pregnancy; Proto-Oncogene Proteins

2017
Novel insights into mitochondrial molecular targets of iron-induced neurodegeneration: Reversal by cannabidiol.
    Brain research bulletin, 2018, Volume: 139

    Topics: 5-Methylcytosine; Animals; Animals, Newborn; Cannabidiol; Creatine Kinase; Disease Models, Animal; DNA Methylation; DNA, Mitochondrial; Female; Gene Expression Regulation; Hippocampus; Iron Carbonyl Compounds; Male; Mitochondria; Mitochondrial Proteins; Muscle Proteins; NADH Dehydrogenase; Neurodegenerative Diseases; Pregnancy; Rats; Rats, Wistar

2018
Overexpression of Tet3 in donor cells enhances goat somatic cell nuclear transfer efficiency.
    The FEBS journal, 2018, Volume: 285, Issue:14

    Topics: 5-Methylcytosine; Animals; Blastocyst; Cellular Reprogramming; Cloning, Organism; Dioxygenases; DNA Demethylation; Embryonic Development; Female; Gene Expression Regulation, Developmental; Goats; Male; Nanog Homeobox Protein; Nuclear Transfer Techniques; Octamer Transcription Factor-3; Pregnancy

2018
Expression of TET and 5-HmC in Trophoblast Villi of Women with Normal Pregnancy and with Early Pregnancy Loss.
    Current medical science, 2018, Volume: 38, Issue:3

    Topics: 5-Methylcytosine; Abortion, Spontaneous; Adult; Dioxygenases; DNA; DNA-Binding Proteins; Female; Humans; Mixed Function Oxygenases; Pregnancy; Proto-Oncogene Proteins; RNA, Messenger; Trophoblasts

2018
TET2-Mediated Spatiotemporal Changes of 5-Hydroxymethylcytosine During Organogenesis in the Late Mouse Fetus.
    Anatomical record (Hoboken, N.J. : 2007), 2019, Volume: 302, Issue:6

    Topics: 5-Methylcytosine; Animals; Brain; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Epigenomics; Female; Fetus; Heart; Mice; Organogenesis; Pregnancy; Proto-Oncogene Proteins; Spatio-Temporal Analysis

2019
Trichloroethylene exposure in mid-pregnancy decreased fetal weight and increased placental markers of oxidative stress in rats.
    Reproductive toxicology (Elmsford, N.Y.), 2019, Volume: 83

    Topics: 5-Methylcytosine; 8-Hydroxy-2'-Deoxyguanosine; Animals; Biomarkers; Deoxyguanosine; Dioxygenases; Female; Fetal Weight; Maternal-Fetal Exchange; Oxidative Stress; Placenta; Pregnancy; Rats, Wistar; Solvents; Trichloroethylene

2019
Inter-Cell and Inter-Chromosome Variability of 5-Hydroxymethylcytosine Patterns in Noncultured Human Embryonic and Extraembryonic Cells.
    Cytogenetic and genome research, 2018, Volume: 156, Issue:3

    Topics: 5-Methylcytosine; Cell Communication; Chromosome Aberrations; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 16; Chromosomes, Human, Pair 9; DNA Methylation; Embryo, Mammalian; Epigenesis, Genetic; Female; Fluorescent Antibody Technique; Humans; Pregnancy; Pregnancy Trimester, First

2018
Cell-Free DNA Release by Mouse Fetal Membranes.
    Reproductive sciences (Thousand Oaks, Calif.), 2019, Volume: 26, Issue:6

    Topics: 5-Methylcytosine; Amino Acid Chloromethyl Ketones; Animals; Apoptosis; Caspase Inhibitors; Cell-Free Nucleic Acids; Culture Media, Conditioned; Extraembryonic Membranes; Female; Mice; Placenta; Pregnancy; Quinolines; Signal Transduction; Thapsigargin

2019
Tet3 is required for normal in vitro fertilization preimplantation embryos development of bovine.
    Molecular reproduction and development, 2019, Volume: 86, Issue:3

    Topics: 5-Methylcytosine; Animals; Cattle; Cell Differentiation; Dioxygenases; DNA Methylation; Embryonic Development; Female; Nanog Homeobox Protein; Octamer Transcription Factor-3; Pregnancy; Promoter Regions, Genetic; RNA, Long Noncoding

2019
Vitrification of murine mature metaphase II oocytes perturbs DNA methylation reprogramming during preimplantation embryo development.
    Cryobiology, 2019, Volume: 87

    Topics: 5-Methylcytosine; Animals; Blastocyst; Cryopreservation; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Embryonic Development; Female; Fertilization in Vitro; Metaphase; Mice; Morula; Oocytes; Oogenesis; Pregnancy; Proto-Oncogene Proteins; Vitrification

2019
Assessment and site-specific manipulation of DNA (hydroxy-)methylation during mouse corticogenesis.
    Life science alliance, 2019, Volume: 2, Issue:2

    Topics: 5-Methylcytosine; Animals; Cadherins; Cell Differentiation; Cell Lineage; CRISPR-Associated Protein 9; Cytosine; DNA Methylation; DNA-Binding Proteins; Embryonic Stem Cells; Epigenesis, Genetic; Female; Gene Expression Regulation, Developmental; Mice; Mice, Inbred C57BL; Neural Stem Cells; Neurogenesis; Oncogene Proteins, Fusion; Pregnancy; Proto-Oncogene Proteins; Transcription Factors; Transcriptome

2019
Characterization of 5-methylcytosine and 5-hydroxymethylcytosine in human placenta cell types across gestation.
    Epigenetics, 2019, Volume: 14, Issue:7

    Topics: 5-Methylcytosine; Abortion, Legal; Adult; DNA Methylation; Epigenesis, Genetic; Female; Humans; Placenta; Placentation; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Trophoblasts

2019
Decreased global DNA hydroxymethylation in neural tube defects: Association with polycyclic aromatic hydrocarbons.
    Epigenetics, 2019, Volume: 14, Issue:10

    Topics: 5-Methylcytosine; Animals; Case-Control Studies; Disease Models, Animal; Embryo Culture Techniques; Female; Humans; Linear Models; Liver; Male; Maternal Exposure; Mice; Neural Tube Defects; Polycyclic Aromatic Hydrocarbons; Pregnancy; Superoxide Dismutase

2019
Altered expression of epigenetic regulators and imprinted genes in human placenta and fetal tissues from second trimester spontaneous pregnancy losses.
    Epigenetics, 2019, Volume: 14, Issue:12

    Topics: 5-Methylcytosine; Aborted Fetus; Abortion, Spontaneous; Adult; Cyclin-Dependent Kinase Inhibitor p57; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Female; Genomic Imprinting; Humans; Insulin-Like Growth Factor II; Placenta; Pregnancy; Pregnancy Trimester, Second; Proto-Oncogene Proteins; RNA, Long Noncoding

2019
Maternal folate depletion and high-fat feeding from weaning affects DNA methylation and DNA repair in brain of adult offspring.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2013, Volume: 27, Issue:8

    Topics: 5-Methylcytosine; Animals; Base Sequence; Brain; Diet, High-Fat; Dietary Fats; DNA Damage; DNA Glycosylases; DNA Methylation; DNA Repair; DNA-Binding Proteins; Female; Folic Acid; Gene Expression Regulation, Developmental; Male; Maternal Nutritional Physiological Phenomena; Mice; Mice, Inbred C57BL; Molecular Sequence Data; Pregnancy; Reverse Transcriptase Polymerase Chain Reaction; Vitamin B Complex; Weaning; X-ray Repair Cross Complementing Protein 1

2013
Cadmium exposure and the epigenome: Exposure-associated patterns of DNA methylation in leukocytes from mother-baby pairs.
    Epigenetics, 2014, Volume: 9, Issue:2

    Topics: 5-Methylcytosine; Cadmium; Cotinine; CpG Islands; DNA Methylation; Environmental Pollutants; Epigenesis, Genetic; Female; Gene Expression Regulation; Genome, Human; Humans; Infant, Newborn; Leukocytes; Male; Maternal Exposure; Maternal-Fetal Exchange; Pregnancy; Promoter Regions, Genetic

2014
Prenatal exposure to BPA alters the epigenome of the rat mammary gland and increases the propensity to neoplastic development.
    PloS one, 2014, Volume: 9, Issue:7

    Topics: 5-Methylcytosine; Animals; Antibodies; Benzhydryl Compounds; Carcinogenesis; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation; Histones; Lactalbumin; Mammary Glands, Animal; Oligonucleotide Array Sequence Analysis; Phenols; Pregnancy; Prenatal Exposure Delayed Effects; Promoter Regions, Genetic; Rats; Rats, Wistar; Tandem Mass Spectrometry; Transcription Initiation Site

2014
Prenatal arsenic exposure and the epigenome: identifying sites of 5-methylcytosine alterations that predict functional changes in gene expression in newborn cord blood and subsequent birth outcomes.
    Toxicological sciences : an official journal of the Society of Toxicology, 2015, Volume: 143, Issue:1

    Topics: 5-Methylcytosine; 5' Untranslated Regions; Arsenic; Arsenic Poisoning; Cephalometry; Cohort Studies; CpG Islands; DNA Methylation; Epigenesis, Genetic; Epigenomics; Exons; Female; Fetal Blood; Gene Expression Regulation, Developmental; Gestational Age; Head; Humans; Infant, Newborn; Leukocytes; Maternal Exposure; Mexico; Pregnancy; Pregnancy Outcome; Prenatal Exposure Delayed Effects; Risk Assessment; RNA, Messenger; Water Pollutants, Chemical

2015
Haploinsufficiency, but not defective paternal 5mC oxidation, accounts for the developmental defects of maternal Tet3 knockouts.
    Cell reports, 2015, Feb-03, Volume: 10, Issue:4

    Topics: 5-Methylcytosine; Animals; Blastocyst; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Female; Haploinsufficiency; Male; Mice; Mice, Knockout; Oxidation-Reduction; Pregnancy; Proto-Oncogene Proteins; Zygote

2015
Impaired active DNA demethylation in zygotes generated by round spermatid injection.
    Human reproduction (Oxford, England), 2015, Volume: 30, Issue:5

    Topics: 5-Methylcytosine; Animals; Cell Nucleus; Chorionic Gonadotropin; Cytosine; DNA Methylation; Embryo Transfer; Female; Germ Cells; Histones; Humans; Male; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Inbred ICR; Microscopy, Fluorescence; Oocytes; Pregnancy; Pregnancy, Animal; Sperm Injections, Intracytoplasmic; Spermatids; Zygote

2015
Placental 5-methylcytosine and 5-hydroxymethylcytosine patterns associate with size at birth.
    Epigenetics, 2015, Volume: 10, Issue:8

    Topics: 5-Methylcytosine; Birth Weight; Cyclin-Dependent Kinase Inhibitor p57; Cytosine; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Developmental; Genomic Imprinting; Humans; Insulin-Like Growth Factor II; Placenta; Pregnancy

2015
Genome-Wide Mapping of 5mC and 5hmC Identified Differentially Modified Genomic Regions in Late-Onset Severe Preeclampsia: A Pilot Study.
    PloS one, 2015, Volume: 10, Issue:7

    Topics: 5-Methylcytosine; Adult; Cytosine; DNA Methylation; Epigenesis, Genetic; ErbB Receptors; Female; Genome-Wide Association Study; Genome, Human; Humans; Pilot Projects; Pre-Eclampsia; Pregnancy; Receptor-Like Protein Tyrosine Phosphatases, Class 8; Signal Transduction

2015
Maternal TET3 is dispensable for embryonic development but is required for neonatal growth.
    Scientific reports, 2015, Oct-28, Volume: 5

    Topics: 5-Methylcytosine; Animals; Cell Line; Cell Nucleus; Dioxygenases; DNA Methylation; DNA Replication; DNA-Binding Proteins; Embryo, Mammalian; Embryonic Development; Female; Fertilization; Gene Expression Regulation, Developmental; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; NIH 3T3 Cells; Oocytes; Pregnancy; Proto-Oncogene Proteins; Zygote

2015
5-Hydroxymethylcytosine-mediated alteration of transposon activity associated with the exposure to adverse in utero environments in human.
    Human molecular genetics, 2016, 06-01, Volume: 25, Issue:11

    Topics: 5-Methylcytosine; Adult; Ascorbic Acid; Diabetes, Gestational; Dioxygenases; DNA Methylation; DNA Transposable Elements; DNA-Binding Proteins; Epigenesis, Genetic; Female; Gene Expression Regulation, Developmental; Humans; Pre-Eclampsia; Pregnancy; Proto-Oncogene Proteins

2016
Hydroxymethylation is uniquely distributed within term placenta, and is associated with gene expression.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2016, Volume: 30, Issue:8

    Topics: 5-Methylcytosine; Cytosine; DNA; Female; Gene Expression Regulation; Humans; Infant, Newborn; Placenta; Pregnancy

2016
Increased global placental DNA methylation levels are associated with gestational diabetes.
    Clinical epigenetics, 2016, Volume: 8

    Topics: 5-Methylcytosine; Adult; Cohort Studies; Diabetes, Gestational; DNA Methylation; Epigenesis, Genetic; Female; Genome-Wide Association Study; Humans; Logistic Models; Placenta; Pregnancy; Pregnancy Outcome

2016
Maternal Methyl-Group Donor Intake and Global DNA (Hydroxy)Methylation before and during Pregnancy.
    Nutrients, 2016, Aug-06, Volume: 8, Issue:8

    Topics: 5-Methylcytosine; Adult; Belgium; Betaine; Biomarkers; Choline; Cohort Studies; Cytosine; Diet; Dietary Supplements; DNA Methylation; Feeding Behavior; Female; Folic Acid; Humans; Hydroxylation; Leukocytes; Longitudinal Studies; Maternal Nutritional Physiological Phenomena; Methionine; Pregnancy; Prospective Studies; Self Report

2016
Absence of paternal accessory sex gland secretions disturbs epigenetic reprogramming and expression of Igf2 and Dlk1 in golden hamster embryos.
    Theriogenology, 2009, Volume: 71, Issue:9

    Topics: 5-Methylcytosine; Acetylation; Animals; Blastocyst; Cricetinae; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA Modification Methylases; Embryonic Development; Epigenesis, Genetic; Female; Fluorescent Antibody Technique; Gene Expression; Genitalia, Male; Histones; In Situ Hybridization; Insulin-Like Growth Factor II; Intracellular Signaling Peptides and Proteins; Male; Membrane Proteins; Mesocricetus; Pregnancy; Reverse Transcriptase Polymerase Chain Reaction; Spermatozoa

2009
Cellular DNA methylation program during neurulation and its alteration by alcohol exposure.
    Birth defects research. Part A, Clinical and molecular teratology, 2011, Volume: 91, Issue:8

    Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Differentiation; Cells, Cultured; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Ethanol; Female; Male; Mice; Mice, Inbred C57BL; Neural Stem Cells; Neural Tube; Neurulation; Pregnancy; Repressor Proteins; Transcription Factors

2011
Trophoblast-specific DNA methylation occurs after the segregation of the trophectoderm and inner cell mass in the mouse periimplantation embryo.
    Epigenetics, 2012, Volume: 7, Issue:2

    Topics: 5-Methylcytosine; Animals; Blastocyst Inner Cell Mass; DNA Methylation; Ectoderm; Embryo Implantation; Embryonic Stem Cells; Female; Genome; Germ Layers; Humans; Mice; Mice, Inbred C57BL; Organ Specificity; Placenta; Pregnancy; Trophoblasts

2012
Behavioral and neurobiological effects of prenatal stress exposure in male and female APPswe/PS1dE9 mice.
    Neurobiology of aging, 2013, Volume: 34, Issue:1

    Topics: 5-Methylcytosine; Alzheimer Disease; Amyloid beta-Protein Precursor; Animals; Behavioral Symptoms; Benzofurans; Cognition Disorders; Cytosine; Disease Models, Animal; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; Female; Hippocampus; Humans; Male; Memory Disorders; Mice; Mice, Transgenic; Pregnancy; Prenatal Exposure Delayed Effects; Presenilin-1; Quinolines; Space Perception; Stress, Psychological

2013
Absence of global genomic cytosine methylation pattern erasure during medaka (Oryzias latipes) early embryo development.
    Comparative biochemistry and physiology. Part B, Biochemistry & molecular biology, 2002, Volume: 133, Issue:4

    Topics: 5-Methylcytosine; Animals; Blotting, Southern; Cytosine; DNA; DNA Methylation; DNA Probes; Embryonic and Fetal Development; Female; Genome; Genomic Imprinting; Male; Morphogenesis; Oryzias; Pregnancy; Restriction Mapping; Species Specificity

2002
Genome-wide epigenetic alterations in cloned bovine fetuses.
    Biology of reproduction, 2003, Volume: 68, Issue:3

    Topics: 5-Methylcytosine; Animals; Cattle; Cloning, Organism; Cytosine; DNA Methylation; Female; Fetal Viability; Fetus; Pregnancy

2003
Influence of global sperm DNA methylation on IVF results.
    Human reproduction (Oxford, England), 2005, Volume: 20, Issue:3

    Topics: 5-Methylcytosine; DNA Methylation; Embryo Transfer; Embryo, Mammalian; Female; Fertilization; Fertilization in Vitro; Flow Cytometry; Fluorescein-5-isothiocyanate; Fluorescent Dyes; Humans; Immunologic Techniques; Male; Pregnancy; Pregnancy Rate; Prospective Studies; Spermatozoa; Staining and Labeling; Treatment Outcome

2005
Tissue-specific effects of in vitro fertilization procedures on genomic cytosine methylation levels in overgrown and normal sized bovine fetuses.
    Biology of reproduction, 2006, Volume: 75, Issue:1

    Topics: 5-Methylcytosine; Animals; Brain; Brain Chemistry; Cattle; DNA Methylation; Epigenesis, Genetic; Female; Fertilization in Vitro; Fetal Development; Fetal Weight; Fetus; Follicle Stimulating Hormone; Genome; Liver; Male; Muscles; Phenotype; Pregnancy

2006
[DNA sperm methylation in assisted reproductive techniques].
    Gynecologie, obstetrique & fertilite, 2006, Volume: 34, Issue:9

    Topics: 5-Methylcytosine; DNA; DNA Methylation; Female; Fertilization in Vitro; Humans; Infertility, Male; Male; Pregnancy; Reproductive Techniques, Assisted; Spermatozoa

2006
Relative levels of methylation in human growth hormone and chorionic somatomammotropin genes in expressing and non-expressing tissues.
    Nucleic acids research, 1982, Jun-11, Volume: 10, Issue:11

    Topics: 5-Methylcytosine; Cell Nucleus; Cloning, Molecular; Cytosine; DNA; DNA Restriction Enzymes; Female; Genes; Growth Hormone; Humans; Hydatidiform Mole; Methylation; Nucleic Acid Hybridization; Pituitary Gland, Anterior; Placenta; Placental Lactogen; Pregnancy; Uterine Neoplasms

1982
The 5-methylcytosine content of DNA from human tumors.
    Nucleic acids research, 1983, Oct-11, Volume: 11, Issue:19

    Topics: 5-Methylcytosine; Brain Chemistry; Cytosine; DNA; DNA Restriction Enzymes; DNA, Neoplasm; Female; Humans; Methylation; Neoplasms; Placenta; Pregnancy; Structure-Activity Relationship

1983
Mouse mammary tumor virus DNA methylation: tissue-specific variation.
    Virology, 1984, Jul-15, Volume: 136, Issue:1

    Topics: 5-Methylcytosine; Animals; Base Sequence; Cytosine; DNA Restriction Enzymes; DNA, Viral; Female; Genes, Viral; Lactation; Mammary Glands, Animal; Mammary Tumor Virus, Mouse; Methylation; Mice; Mice, Inbred BALB C; Pregnancy; Repetitive Sequences, Nucleic Acid; RNA, Viral; Spleen; Transcription, Genetic

1984
The 5-methylcytosine content of highly repeated sequences in human DNA.
    Nucleic acids research, 1983, May-25, Volume: 11, Issue:10

    Topics: 5-Methylcytosine; Cytosine; DNA; Female; Genes; Humans; Kinetics; Male; Methylation; Nucleic Acid Hybridization; Placenta; Pregnancy; Repetitive Sequences, Nucleic Acid; Spermatozoa

1983
5-methylcytosine content in different organs of the mouse and rat, several tumors and in mice embryos.
    The International journal of biochemistry, 1983, Volume: 15, Issue:5

    Topics: 5-Methylcytosine; Animals; Cytosine; DNA; DNA, Neoplasm; Embryo, Mammalian; Female; Kidney; Liver; Mice; Neoplasm Transplantation; Neoplasms, Experimental; Plasmacytoma; Pregnancy; Rats

1983
Amount and distribution of 5-methylcytosine in human DNA from different types of tissues of cells.
    Nucleic acids research, 1982, Apr-24, Volume: 10, Issue:8

    Topics: 5-Methylcytosine; Cell Line; Cells, Cultured; Cytosine; DNA; DNA, Neoplasm; Female; Fibroblasts; Humans; Kinetics; Lymphocytes; Nucleic Acid Renaturation; Organ Specificity; Pregnancy; Skin

1982
Methylation of reiterated sequences in mammalian DNAs. Effects of the tissue type, age, malignancy and hormonal induction.
    Biochimica et biophysica acta, 1981, Apr-27, Volume: 653, Issue:2

    Topics: 5-Methylcytosine; Animals; Carcinoma, Ehrlich Tumor; Cattle; Cattle Diseases; Cytosine; DNA; DNA, Neoplasm; Embryo, Mammalian; Female; Hydrocortisone; Liver; Lymphoma; Male; Methylation; Mice; Myocardium; Pregnancy; Rats; Repetitive Sequences, Nucleic Acid; Thymus Gland

1981
An embryonic-like methylation pattern of classical satellite DNA is observed in ICF syndrome.
    Human molecular genetics, 1993, Volume: 2, Issue:6

    Topics: 5-Methylcytosine; Adult; Centromere; Child; Child, Preschool; Chromosome Aberrations; Chromosome Disorders; Cytosine; DNA, Satellite; Embryo, Mammalian; Face; Female; Genetic Markers; Humans; Immunologic Deficiency Syndromes; Infant; Leukocytes; Male; Methylation; Placenta; Polymorphism, Restriction Fragment Length; Pregnancy; Repetitive Sequences, Nucleic Acid; Testis

1993
Chromosome methylation patterns during mammalian preimplantation development.
    Genes & development, 1998, Jul-15, Volume: 12, Issue:14

    Topics: 5-Methylcytosine; Animals; Antibodies, Monoclonal; Cytosine; DNA Methylation; Embryonic and Fetal Development; Embryonic Development; Female; Humans; Male; Mammals; Mice; Mice, Inbred C57BL; Mice, Inbred CBA; Pregnancy

1998
Maternal epigenetics and methyl supplements affect agouti gene expression in Avy/a mice.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1998, Volume: 12, Issue:11

    Topics: 5-Methylcytosine; Agouti Signaling Protein; Animals; Betaine; Choline; Cytosine; Dietary Supplements; Female; Folic Acid; Gene Expression Regulation; Genomic Imprinting; Hair Color; Intercellular Signaling Peptides and Proteins; Male; Methionine; Mice; Mice, Inbred Strains; Pregnancy; Proteins; S-Adenosylmethionine; Vitamin B 12; Zinc

1998
Ethanol consumption inhibits fetal DNA methylation in mice: implications for the fetal alcohol syndrome.
    Alcoholism, clinical and experimental research, 1991, Volume: 15, Issue:3

    Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cytosine; DNA Damage; DNA Mutational Analysis; DNA-Cytosine Methylases; Female; Fetal Alcohol Spectrum Disorders; Gene Expression Regulation; Mice; Pregnancy

1991
[A study on the role of DNA methylation within hCG and hPL genes in trophoblastic disease].
    Nihon Sanka Fujinka Gakkai zasshi, 1987, Volume: 39, Issue:12

    Topics: 5-Methylcytosine; Chorionic Gonadotropin; Chromatography, High Pressure Liquid; Cytosine; DNA, Neoplasm; Female; Gene Expression Regulation; Humans; Methylation; Oncogenes; Placental Lactogen; Pregnancy; Trophoblastic Neoplasms; Uterine Neoplasms

1987
Localization, in human placenta, of the tightly bound form of DNA methylase in the higher order of chromatin organization.
    Biochimica et biophysica acta, 1988, Nov-10, Volume: 951, Issue:1

    Topics: 5-Methylcytosine; Chromatin; Chromatography, High Pressure Liquid; Cytosine; Deoxyribonuclease I; DNA; DNA (Cytosine-5-)-Methyltransferases; Electrophoresis; Female; Gas Chromatography-Mass Spectrometry; Humans; Placenta; Pregnancy; Proteins

1988