5-methylcytosine has been researched along with Lung Neoplasms in 27 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (3.70) | 18.7374 |
| 1990's | 3 (11.11) | 18.2507 |
| 2000's | 8 (29.63) | 29.6817 |
| 2010's | 9 (33.33) | 24.3611 |
| 2020's | 6 (22.22) | 2.80 |
| Authors | Studies |
|---|---|
| Hu, X; Huang, R; Luo, K; Shi, H; Xie, D; Yan, X; Zhang, J; Zhang, W; Zhao, B | 1 |
| Ma, L; Meng, F; Miao, Y; Tian, X; Wang, Y; Xia, J; Yu, W; Zhang, C; Zhang, X | 1 |
| Feng, X; He, R; Li, W; Yang, K; Zeng, J; Zhou, X | 1 |
| Cui, W; Hostetter, G; Huang, Z; Jin, SG; Johnson, J; Lau, KH; Pfeifer, GP | 1 |
| Christiani, DC; Du, M; Guo, Y; Hou, L; Hutchinson, JN; Lin, X; Mucci, LA; Su, L; Wang, J; Wang, Z; Yuan, Q; Zheng, Y | 1 |
| Chellamuthu, A; Gray, SG | 1 |
| Adachi, T; Hara, H; Kamiya, T; Mori, N; Nakahara, R | 1 |
| Gao, C; Han, X; Li, X; Liu, R; Qi, Z; Sun, B; Tian, X; Wang, Y; Xing, Y; Yang, YG; Zhang, J; Zhang, X | 1 |
| Betz, BL; Brown, NA; Cascalho, M; Cooke, A; Davis, A; El Kadi, N; Hassan, KA; Kalemkerian, GP; Korkaya, H; Vadnala, V; Wang, L | 1 |
| Krais, AM; Meister, M; Park, YJ; Plass, C; Reifenberger, G; Schmeiser, HH | 1 |
| Brown, H; Chresta, CM; Delpuech, O; Taylor, MA; Wappett, M | 1 |
| Blanquart, C; Deshayes, S; Fonteneau, JF; Grégoire, M; Guilly, MN; Hulin, P; Le Martelot, V; Liddell, C; Nader, JS; Ouacher, A; Pouliquen, DL; Robard, M; Roulois, D | 1 |
| Fujii, S; Harada, T; Kikuchi, A; Kondo, Y; Matsumoto, S; Morii, E; Nojima, S; Sato, S; Shinjo, K; Toyosawa, S; Usami, Y | 1 |
| Chang, JW; Chen, CY; Hsu, HS; Juan, LJ; Lin, RK; Lu, YY; Tang, YA; Wang, YC; Wu, CY; Yang, PC; Yang, YC | 1 |
| Jiang, Y; Jin, SG; Krex, D; Lu, Q; Pfeifer, GP; Qiu, R; Rauch, TA; Schackert, G; Wang, Y | 1 |
| Avila, S; Capella, G; Esteller, M; Fraga, MF; Herman, JG; Paz, MF; Peinado, MA; Pollan, M; Sanchez-Cespedes, M | 1 |
| Kramer, P; Lubet, R; Perreira, M; Tao, L; Wang, W | 1 |
| Cha, SI; Choi, JE; Jung, TH; Kam, S; Kang, YM; Kim, CH; Lee, SJ; Lee, WK; Park, JY; Shin, MC | 1 |
| Briggs, RS; Day, IN; Ganderton, RH | 1 |
| Baylin, SB; Burger, PC; Gabrielson, E; Herman, JG; Lee, DJ; Mao, L; Merlo, A; Sidransky, D | 1 |
| Denissenko, MF; Pfeifer, GP | 1 |
| Denissenko, MF; Pfeifer, GP; Tang, M | 1 |
| Pfeifer, GP | 1 |
| Bates, S; Chin, PL; Dammann, R; Li, C; Pfeifer, GP; Yoon, JH | 1 |
| Frost, AR; Grizzle, WE; Heimburger, DC; Johanning, GL; Manne, U; Niveleau, A; Piyathilake, CJ; Whiteside, MA | 1 |
| Bell, WC; Frost, AR; Grizzle, WE; Heimburger, DC; Johanning, GL; Niveleau, A; Oelschlager, D; Piyathilake, CJ; Weiss, H | 1 |
| Nyce, J | 1 |
4 review(s) available for 5-methylcytosine and Lung Neoplasms
| Article | Year |
|---|---|
The RNA Methyltransferase NSUN2 and Its Potential Roles in Cancer.
Topics: 5-Methylcytosine; Animals; Breast Neoplasms; Colorectal Neoplasms; Female; Humans; Lung Neoplasms; Methylation; Methyltransferases; Mice; Phylogeny; RNA, Messenger | 2020 |
Formation and repair of DNA lesions in the p53 gene: relation to cancer mutations?
Topics: 5-Methylcytosine; Animals; Benzo(a)pyrene; Breast Neoplasms; Carcinogens, Environmental; Colonic Neoplasms; Cytosine; Deamination; DNA Adducts; DNA Damage; DNA Mutational Analysis; DNA Repair; Genes, p53; Humans; Lung Neoplasms; Mice; Mutagenesis; Neoplasms; Neoplasms, Radiation-Induced; Selection, Genetic; Skin Neoplasms; Smoking; Tumor Suppressor Protein p53; Ultraviolet Rays | 1998 |
Mutation hotspots and DNA methylation.
Topics: 5-Methylcytosine; Carcinogens; CpG Islands; Cytosine; DNA Methylation; Genes, p53; Genes, Tumor Suppressor; Lung Neoplasms; Mutagenesis; Skin Neoplasms | 2000 |
p53 mutational spectra and the role of methylated CpG sequences.
Topics: 5-Methylcytosine; Carcinogens; CpG Islands; Cytosine; DNA Methylation; DNA Repair; DNA, Neoplasm; Genes, p53; Humans; Lung Neoplasms; Mutation; Skin Neoplasms; Smoking; Sunlight | 2000 |
23 other study(ies) available for 5-methylcytosine and Lung Neoplasms
| Article | Year |
|---|---|
Integrated 5-hydroxymethylcytosine and fragmentation signatures as enhanced biomarkers in lung cancer.
Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; China; DNA Fragmentation; DNA Methylation; Female; Humans; Lung Neoplasms; Male; Middle Aged | 2022 |
YAP 5-methylcytosine modification increases its mRNA stability and promotes the transcription of exosome secretion-related genes in lung adenocarcinoma.
Topics: 5-Methylcytosine; Adenocarcinoma of Lung; Exosomes; Humans; Lung Neoplasms; MicroRNAs; RNA Stability; Transcription Factors | 2023 |
Construction of a 5-methylcytosine-Related Molecular Signature to Inform the Prognosis and Immunotherapy of Lung Squamous Cell Carcinoma.
Topics: 5-Methylcytosine; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Humans; Immunologic Factors; Immunotherapy; Lung; Lung Neoplasms | 2022 |
Deficiency of the Polycomb Protein RYBP and TET Methylcytosine Oxidases Promotes Extensive CpG Island Hypermethylation and Malignant Transformation.
Topics: 5-Methylcytosine; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; CpG Islands; DNA; DNA Methylation; Humans; Lung Neoplasms; Mice; Oxidoreductases; Polycomb Repressive Complex 1; Repressor Proteins | 2023 |
Epigenomic analysis of 5-hydroxymethylcytosine (5hmC) reveals novel DNA methylation markers for lung cancers.
Topics: 5-Methylcytosine; Biomarkers, Tumor; Computational Biology; CpG Islands; Disease Susceptibility; DNA Methylation; Epigenesis, Genetic; Epigenomics; Gene Expression Profiling; Genetic Loci; Genetic Predisposition to Disease; Humans; Lung Neoplasms | 2020 |
Ten-eleven translocation 1 functions as a mediator of SOD3 expression in human lung cancer A549 cells.
Topics: 5-Methylcytosine; A549 Cells; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Mixed Function Oxygenases; Oxidation-Reduction; Proto-Oncogene Proteins; Superoxide Dismutase | 2017 |
5-Hydroxymethylome in Circulating Cell-free DNA as A Potential Biomarker for Non-small-cell Lung Cancer.
Topics: 5-Methylcytosine; Biomarkers, Tumor; Carcinoma, Non-Small-Cell Lung; Case-Control Studies; Circulating Tumor DNA; DNA Methylation; Epigenomics; Female; Humans; Lung Neoplasms; Male; Middle Aged | 2018 |
The EGFR T790M Mutation Is Acquired through AICDA-Mediated Deamination of 5-Methylcytosine following TKI Treatment in Lung Cancer.
Topics: 5-Methylcytosine; Aged; Cell Line, Tumor; Cytidine Deaminase; Deamination; Disease Progression; ErbB Receptors; Female; Humans; Hydrolysis; Lung Neoplasms; Male; Mass Spectrometry; Methylation; Middle Aged; Mutation; NF-kappa B; Polymerase Chain Reaction; Protein-Tyrosine Kinases | 2018 |
Sensitive detection of hydroxymethylcytosine levels in normal and neoplastic cells and tissues.
Topics: 5-Methylcytosine; Animals; Cell Dedifferentiation; DNA Methylation; Electrophoresis, Capillary; Fluorescence; Glioma; Humans; Lung Neoplasms; Mice; Neoplasms | 2019 |
Enhanced MAPK signaling drives ETS1-mediated induction of miR-29b leading to downregulation of TET1 and changes in epigenetic modifications in a subset of lung SCC.
Topics: 5-Methylcytosine; Azacitidine; Carcinoma, Squamous Cell; Cell Line, Tumor; Computational Biology; Down-Regulation; Epigenesis, Genetic; Humans; Lung Neoplasms; MAP Kinase Signaling System; MicroRNAs; Mixed Function Oxygenases; Proto-Oncogene Protein c-ets-1; Proto-Oncogene Proteins; Tumor Escape | 2016 |
Characterization of preneoplastic and neoplastic rat mesothelial cell lines: the involvement of TETs, DNMTs, and 5-hydroxymethylcytosine.
Topics: 5-Methylcytosine; Animals; Asbestos, Crocidolite; Biomarkers, Tumor; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p18; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; Epithelial Cells; Epithelium; Humans; Karyotype; Lung Neoplasms; Mesothelioma; Mesothelioma, Malignant; Mixed Function Oxygenases; Precancerous Conditions; Proto-Oncogene Proteins; Rats; Rats, Inbred F344 | 2016 |
Epigenetic upregulation of ARL4C, due to DNA hypomethylation in the 3'-untranslated region, promotes tumorigenesis of lung squamous cell carcinoma.
Topics: 3' Untranslated Regions; 5-Methylcytosine; A549 Cells; ADP-Ribosylation Factors; Adult; Aged; Aged, 80 and over; Carcinoma, Squamous Cell; Cell Movement; Cell Proliferation; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Head and Neck Neoplasms; HeLa Cells; Humans; Lung Neoplasms; Male; Middle Aged; Mixed Function Oxygenases; Neoplasm Invasiveness; Proto-Oncogene Proteins; RNA Interference; Signal Transduction; Squamous Cell Carcinoma of Head and Neck; Time Factors; Tongue Neoplasms; Transfection; Up-Regulation | 2016 |
Dysregulation of p53/Sp1 control leads to DNA methyltransferase-1 overexpression in lung cancer.
Topics: 5-Methylcytosine; Binding Sites; Cell Line, Tumor; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Immunoprecipitation; Lung Neoplasms; Point Mutation; Promoter Regions, Genetic; Proto-Oncogene Proteins c-mdm2; Sp1 Transcription Factor; Transcription, Genetic; Tumor Suppressor Protein p53; Ubiquitination | 2010 |
5-Hydroxymethylcytosine is strongly depleted in human cancers but its levels do not correlate with IDH1 mutations.
Topics: 5-Methylcytosine; Animals; Base Sequence; Brain; Brain Neoplasms; Carcinoma, Squamous Cell; Cell Line, Tumor; Chromatography, Liquid; Cytosine; DNA-Binding Proteins; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Immunohistochemistry; Isocitrate Dehydrogenase; Lung Neoplasms; Male; Mice; Mixed Function Oxygenases; Molecular Structure; Mutation; Neoplasms; Proto-Oncogene Proteins; Reverse Transcriptase Polymerase Chain Reaction | 2011 |
Germ-line variants in methyl-group metabolism genes and susceptibility to DNA methylation in normal tissues and human primary tumors.
Topics: 5-Methylcytosine; 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenocarcinoma; Breast Neoplasms; Colorectal Neoplasms; CpG Islands; Cystathionine beta-Synthase; Cytosine; DNA Methylation; DNA, Neoplasm; Genetic Predisposition to Disease; Germ-Line Mutation; Humans; Lung Neoplasms; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasms; Oxidoreductases Acting on CH-NH Group Donors | 2002 |
Effects of budesonide on overall 5-methylcytosine levels and specific methylation and messenger RNA expression of the insulin-like growth factor II gene in mouse lung tumors.
Topics: 5-Methylcytosine; Animals; Anticarcinogenic Agents; Budesonide; CpG Islands; DNA Methylation; Female; Gene Expression; Insulin-Like Growth Factor Binding Protein 2; Lung Neoplasms; Mice; Mice, Inbred A; RNA, Messenger | 2004 |
Glu346Lys polymorphism in the methyl-CpG binding domain 4 gene and the risk of primary lung cancer.
Topics: 5-Methylcytosine; Adenocarcinoma; Aged; Biomarkers, Tumor; Carcinoma, Small Cell; Carcinoma, Squamous Cell; DNA Repair; Endodeoxyribonucleases; Female; Genetic Predisposition to Disease; Genotype; Humans; Lung Neoplasms; Male; Matched-Pair Analysis; Middle Aged; Polymorphism, Genetic; Risk | 2006 |
Patterns of DNA methylation of the parathyroid hormone-related protein gene in human lung carcinoma.
Topics: 5-Methylcytosine; Cytosine; DNA, Neoplasm; Electrophoresis, Agar Gel; Humans; Lung; Lung Neoplasms; Male; Methylation; Neoplasm Proteins; Parathyroid Hormone; Parathyroid Hormone-Related Protein; Proteins; Restriction Mapping; Spermatozoa | 1995 |
5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers.
Topics: 5-Methylcytosine; Alleles; Azacitidine; Base Sequence; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Carrier Proteins; Chromosomes, Human, Pair 9; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Cytosine; Decitabine; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Glioma; Head and Neck Neoplasms; Humans; Lung Neoplasms; Methylation; Molecular Sequence Data; Neoplasm Proteins; Neoplasms; Sequence Deletion; Transcription, Genetic; Tumor Cells, Cultured | 1995 |
Epigenetic inactivation of a RAS association domain family protein from the lung tumour suppressor locus 3p21.3.
Topics: 5-Methylcytosine; Alternative Splicing; Amino Acid Sequence; Animals; Base Sequence; Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Chromosomes, Human, Pair 3; CpG Islands; Cytosine; DNA Methylation; DNA-Binding Proteins; DNA, Complementary; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; HeLa Cells; HT29 Cells; Humans; Lung Neoplasms; Mice; Molecular Sequence Data; Mutation, Missense; Neoplasm Proteins; ral Guanine Nucleotide Exchange Factor; ras Proteins; Rats; RNA-Binding Proteins; Sp1 Transcription Factor; Tumor Suppressor Proteins; Xeroderma Pigmentosum Group A Protein | 2000 |
Immunohistochemical evaluation of global DNA methylation: comparison with in vitro radiolabeled methyl incorporation assay.
Topics: 5-Methylcytosine; Biological Assay; Carcinoma, Squamous Cell; Cytosine; DNA Methylation; DNA, Neoplasm; Humans; Immunoenzyme Techniques; Isotope Labeling; Lung; Lung Neoplasms; Tritium | 2000 |
Altered global methylation of DNA: an epigenetic difference in susceptibility for lung cancer is associated with its progression.
Topics: 5-Methylcytosine; Antibodies, Monoclonal; Bronchi; Carcinoma, Squamous Cell; Cytosine; Disease Progression; Disease Susceptibility; DNA Methylation; DNA, Neoplasm; Fluorescent Antibody Technique, Indirect; Genetic Predisposition to Disease; Humans; Hyperplasia; Lung Neoplasms; Precancerous Conditions; Respiratory Mucosa; Smoking | 2001 |
Drug-induced DNA hypermethylation and drug resistance in human tumors.
Topics: 5-Methylcytosine; Antineoplastic Agents; Carcinoma, Squamous Cell; Cell Line; Cell Survival; Cytosine; DNA Replication; DNA, Neoplasm; Drug Resistance; Humans; Lung Neoplasms; Methylation; Rhabdomyosarcoma; Tumor Cells, Cultured; Tumor Stem Cell Assay; Zidovudine | 1989 |