Page last updated: 2024-08-24

5-methylcytosine and Liver Neoplasms

5-methylcytosine has been researched along with Liver Neoplasms in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (3.23)29.6817
2010's17 (54.84)24.3611
2020's13 (41.94)2.80

Authors

AuthorsStudies
Alam, A; An, J; Kim, H; Ko, M; Lim, S; Sideeq Bhat, K1
Cai, J; Chu, Y; Fan, J; Fu, Y; Huang, C; Jiao, M; Ke, A; Li, Z; Liu, R; Lu, Z; Shi, G; Wang, L; Wang, X; Wang, Y; Wang, Z; Wen, H; Xia, J; Ye, D; Zhou, J1
Gao, G; Huang, F; Jiang, D; Wang, J; Yu, J; Zhang, Y; Zhao, J1
Chen, G; Chen, L; Cheng, H; Deng, T; Fan, Y; Gong, P; Niu, X; Tian, Y; Wang, P; Wang, W; Xiao, H; Yang, L; Yang, Y; Yuan, J; Zhang, J; Zhang, P; Zhang, W; Zhang, X1
Cai, JB; Chen, Y; Fan, J; Gao, C; Guo, XJ; Huang, XY; Ke, AW; Lu, JC; Pei, YZ; Shen, YH; Shi, GM; Shi, YG; Sun, QM; Wei, CY; Yang, GH; Yang, X; Zhang, PF; Zhou, J1
Balaseviciute, U; Bech-Serra, JJ; Davalos, V; De La Torre, C; Esteller, M; Fernández-Rebollo, I; García-Prieto, CA; Guarnacci, M; Guil, S; Janin, M; Llovet, JM; Montal, R; Ortiz-Barahona, V; Preiss, T; Schumann, U; Setien, F; Soler, M; Villanueva, A; Yang, L; Zhang, PH1
Dai, E; Dai, M; Feng, J; Jia, Y; Liu, Z; Ye, L; Zhang, H1
Arechederra, M1
Chen, Y; Lin, XY1
Cai, J; Fan, J; He, C; Zhang, W; Zhang, Z1
Battaglia-Hsu, SF; Chen, B; Feng, J; Gong, C; Guo, D; Guo, T; Li, Z; Liu, P; Liu, Z; Wang, H; Wu, P; Xiao, Y; Yao, Y1
Chorley, BN; Corton, JC; Gunewardena, S; Klaassen, CD; Liu, J; Yue Cui, J1
Guo, W; He, Y; Yu, X; Zhang, Q; Zheng, Q1
Cai, Z; Chen, G; Chen, H; Dong, X; He, Y; Hu, X; Liu, J; Liu, X; Wang, Y; Xia, L; Xie, D; Zhang, J; Zhong, S; Zhou, Y1
Cao, Y; Chen, Q; Dai, Z; Fan, J; Gao, DM; Hu, J; Jin, C; Li, XD; Shi, YH; Wang, Z; Yin, D; Yu, L; Zhang, Y; Zhou, J; Zhou, SL; Zhou, ZJ1
Lai, M; Tian, Y; Zhang, H; Zhong, A1
Cao, D; He, Y; Jiang, J; Liu, D; Liu, J; Mo, J; Wang, H1
Wang, P; Yan, Y; Yu, W; Zhang, H1
Chen, BJ; Dresser, K; Zhu, X1
Cai, J; Chen, L; Chiu, BC; Dong, R; Fan, J; Gao, P; Ge, Y; He, C; Huang, X; Ke, A; Lau, WY; Liu, W; Lu, X; Nie, J; Qiu, S; Shen, F; Shi, G; Stroup, EK; Sui, C; Sun, H; Wang, H; Wang, J; Xiao, L; Yang, D; Yang, X; Yang, Y; Zeng, C; Zhang, W; Zhang, X; Zhang, Z; Zhou, J; Zhou, W; Zhu, T; Zhu, Y1
Bian, XW; Bie, P; Chen, X; Cui, Y; Liu, C; Liu, L; Qian, C; Shan, J; Shen, J; Wu, L; Xia, F; Xu, Y; Yang, Z1
Feng, YQ; Huang, JT; Huang, W; Liu, SM; Liu, YJ; Qi, JH; Shen, F; Yuan, BF; Zhou, X1
Hasegawa, J; Miura, N; Shomori, K; Tsuno, S; Wang, X1
Dai, Z; Ding, ZB; Fan, J; Jin, L; Liu, WR; Peng, YF; Qiu, SJ; Shen, YH; Shi, YH; Tian, MX; Yang, LX; Zhou, J1
Chung, TH; Jia, XY; Petterson, A; Sun, X; Tan, D1
Gao, F; Huang, J; Lin, Z; Liu, W; Liu, X; Luo, H; Ou, Y; Wang, J; Wen, B; Xia, Y; Zhang, X; Zhou, B1
Cao, Q; Chen, E; Li, L; Lu, J; Tao, R; Wang, J; Wang, Y; Ye, C; Zhu, D1
Du, Q; Guo, H; Hu, Z; Liang, D; Song, W; Wang, H; Xiong, X; Yang, Z; Ye, M; Zhai, S; Zhang, LH; Zhang, X1
Chen, ML; Feng, YQ; Huang, W; Liu, SM; Qi, JH; Shen, F; Wang, Y; Yuan, BF1
Gertych, A; Oh, JH; Tajbakhsh, J; Wawrowsky, KA; Weisenberger, DJ1
Chen, TC; Hsieh, SY; Lee, WC; Liaw, YF; Lin, CH; Sheen, IS; Shyu, WC1

Reviews

1 review(s) available for 5-methylcytosine and Liver Neoplasms

ArticleYear
Role of ten-eleven translocation proteins and 5-hydroxymethylcytosine in hepatocellular carcinoma.
    Cell proliferation, 2019, Volume: 52, Issue:4

    Topics: 5-Methylcytosine; Animals; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Down-Regulation; Epigenesis, Genetic; Humans; Liver Neoplasms; MicroRNAs; Mixed Function Oxygenases; Proto-Oncogene Proteins; RNA Processing, Post-Transcriptional; Transcription, Genetic

2019

Other Studies

30 other study(ies) available for 5-methylcytosine and Liver Neoplasms

ArticleYear
Rapid and Label-Free Detection of 5-Hydroxymethylcytosine in Genomic DNA Using an Au/ZnO Nanorods Hybrid Nanostructure-Based Electrochemical Sensor.
    Advanced healthcare materials, 2021, Volume: 10, Issue:22

    Topics: 5-Methylcytosine; Carcinoma, Hepatocellular; DNA; Genomics; Gold; Humans; Liver Neoplasms; Metal Nanoparticles; Nanotubes; Zinc Oxide

2021
Ten-eleven translocation-2 inactivation restrains IL-10-producing regulatory B cells to enable antitumor immunity in hepatocellular carcinoma.
    Hepatology (Baltimore, Md.), 2023, 03-01, Volume: 77, Issue:3

    Topics: 5-Methylcytosine; B-Lymphocytes, Regulatory; Carcinoma, Hepatocellular; Humans; Interleukin-10; Liver Neoplasms; Tumor Microenvironment

2023
Value of 5-Hydroxymethylcytosine in HBV-Carrying High-Risk Hepatocellular Carcinoma Population: An Evaluation Based on Differential Analysis.
    Computational and mathematical methods in medicine, 2022, Volume: 2022

    Topics: 5-Methylcytosine; Carcinoma, Hepatocellular; Hepatitis B virus; Hepatitis B, Chronic; Humans; Liver Neoplasms

2022
Crosstalk between 5-methylcytosine and N
    Molecular cancer, 2023, 01-10, Volume: 22, Issue:1

    Topics: 5-Methylcytosine; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Disease Progression; G2 Phase Cell Cycle Checkpoints; Humans; Liver Neoplasms; Pharmacogenetics

2023
Loss of 5-hydroxymethylcytosine induces chemotherapy resistance in hepatocellular carcinoma via the 5-hmC/PCAF/AKT axis.
    Cell death & disease, 2023, 02-02, Volume: 14, Issue:2

    Topics: 5-Methylcytosine; Carcinoma, Hepatocellular; Humans; Liver Neoplasms; Proto-Oncogene Proteins c-akt

2023
Epigenetic inactivation of the 5-methylcytosine RNA methyltransferase NSUN7 is associated with clinical outcome and therapeutic vulnerability in liver cancer.
    Molecular cancer, 2023, 05-12, Volume: 22, Issue:1

    Topics: 5-Methylcytosine; CpG Islands; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Methyltransferases; Proteomics; RNA-Binding Proteins; RNA, Messenger; Transcription Factors

2023
Decrease of 5-hydroxymethylcytosine in hepatitis B virus-related hepatocellular carcinoma: A cross-sectional study.
    Medicine, 2023, Jun-02, Volume: 102, Issue:22

    Topics: 5-Methylcytosine; Carcinoma, Hepatocellular; Cross-Sectional Studies; Cytosine; DNA Methylation; Hepatitis B virus; Humans; Liver Neoplasms; Mixed Function Oxygenases; Proto-Oncogene Proteins

2023
New warning signs on the road: 5-hydroxymethylcytosine-based liquid biopsy for the early detection of hepatocellular carcinoma.
    Gut, 2019, Volume: 68, Issue:12

    Topics: 5-Methylcytosine; Carcinoma, Hepatocellular; Cell-Free Nucleic Acids; Humans; Liquid Biopsy; Liver Neoplasms

2019
Are the 5-hydroxymethylcytosine-based wd-scores really superior over α-fetoprotein for the early diagnosis of hepatocellular carcinoma?
    Gut, 2020, Volume: 69, Issue:10

    Topics: 5-Methylcytosine; alpha-Fetoproteins; Carcinoma, Hepatocellular; Cell-Free Nucleic Acids; Early Diagnosis; Humans; Liver Cirrhosis; Liver Neoplasms

2020
Reply to 'Are the 5-hydroxymethylcytosine-based wd-scores really superior over α-fetoprotein for the early diagnosis of hepatocellular carcinoma?'
    Gut, 2020, Volume: 69, Issue:10

    Topics: 5-Methylcytosine; alpha-Fetoproteins; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell-Free Nucleic Acids; Early Diagnosis; Humans; Liver Neoplasms

2020
LINC00662 promotes hepatocellular carcinoma progression via altering genomic methylation profiles.
    Cell death and differentiation, 2020, Volume: 27, Issue:7

    Topics: 3' Untranslated Regions; 5-Methylcytosine; Adenosylhomocysteinase; Adult; Carcinogenesis; Carcinoma, Hepatocellular; Cell Line, Tumor; Disease Progression; DNA Methylation; Down-Regulation; Gene Expression Regulation, Neoplastic; Genome, Human; Humans; Liver Neoplasms; Methionine Adenosyltransferase; Proteolysis; RNA, Long Noncoding; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Survival Analysis; Ubiquitin; Up-Regulation

2020
Transplacental arsenic exposure produced 5-methylcytosine methylation changes and aberrant microRNA expressions in livers of male fetal mice.
    Toxicology, 2020, 04-15, Volume: 435

    Topics: 5-Methylcytosine; Animals; Arsenites; Cell Transformation, Neoplastic; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Developmental; Gene Expression Regulation, Neoplastic; Gestational Age; Liver; Liver Neoplasms; Male; Maternal Exposure; Mice, Inbred C3H; MicroRNAs; Pregnancy; Sodium Compounds

2020
Overview of distinct 5-methylcytosine profiles of messenger RNA in human hepatocellular carcinoma and paired adjacent non-tumor tissues.
    Journal of translational medicine, 2020, 06-22, Volume: 18, Issue:1

    Topics: 5-Methylcytosine; Carcinoma, Hepatocellular; Humans; Liver Neoplasms; RNA, Messenger; Sequence Analysis, RNA

2020
Liquid biopsy by combining 5-hydroxymethylcytosine signatures of plasma cell-free DNA and protein biomarkers for diagnosis and prognosis of hepatocellular carcinoma.
    ESMO open, 2021, Volume: 6, Issue:1

    Topics: 5-Methylcytosine; Biomarkers; Carcinoma, Hepatocellular; Cell-Free Nucleic Acids; Humans; Liquid Biopsy; Liver Neoplasms; Neoplasm Recurrence, Local; Prognosis

2021
MicroRNA-29a induces loss of 5-hydroxymethylcytosine and promotes metastasis of hepatocellular carcinoma through a TET-SOCS1-MMP9 signaling axis.
    Cell death & disease, 2017, 06-29, Volume: 8, Issue:6

    Topics: 5-Methylcytosine; Adult; Aged; Animals; Carcinoma, Hepatocellular; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Male; Matrix Metalloproteinase 9; Mice; MicroRNAs; Middle Aged; Mixed Function Oxygenases; Neoplasm Metastasis; Proto-Oncogene Proteins; Signal Transduction; Suppressor of Cytokine Signaling 1 Protein; Xenograft Model Antitumor Assays

2017
DNA hydroxymethylation of colorectal primary carcinoma and its association with survival.
    Journal of surgical oncology, 2018, Volume: 117, Issue:5

    Topics: 5-Methylcytosine; Adenocarcinoma; Adenocarcinoma, Mucinous; Biomarkers, Tumor; Colorectal Neoplasms; DNA Methylation; Female; Follow-Up Studies; Gene Expression Regulation, Neoplastic; Humans; Liver Neoplasms; Male; Middle Aged; Prognosis; Survival Rate

2018
Global DNA 5-Hydroxymethylcytosine and 5-Formylcytosine Contents Are Decreased in the Early Stage of Hepatocellular Carcinoma.
    Hepatology (Baltimore, Md.), 2019, Volume: 69, Issue:1

    Topics: 5-Methylcytosine; Carcinoma, Hepatocellular; Cytosine; DNA, Neoplasm; Female; Humans; Liver Neoplasms; Male; Middle Aged; Neoplasm Staging

2019
Loss of 5-hydroxymethylcytosine immunohistochemical expression is a useful diagnostic aid for distinguishing hepatocellular carcinoma in cytology fine needle aspiration specimens.
    Cytopathology : official journal of the British Society for Clinical Cytology, 2019, Volume: 30, Issue:5

    Topics: 5-Methylcytosine; Biopsy, Fine-Needle; Carcinoma, Hepatocellular; Cytodiagnosis; Diagnosis, Differential; Hepatocytes; Humans; Immunohistochemistry; Liver; Liver Neoplasms; Predictive Value of Tests; ROC Curve; Sensitivity and Specificity

2019
Genome-wide mapping of 5-hydroxymethylcytosines in circulating cell-free DNA as a non-invasive approach for early detection of hepatocellular carcinoma.
    Gut, 2019, Volume: 68, Issue:12

    Topics: 5-Methylcytosine; Biomarkers, Tumor; Carcinoma, Hepatocellular; Cell-Free Nucleic Acids; DNA, Neoplasm; Early Detection of Cancer; Female; Genome-Wide Association Study; Humans; Liver Neoplasms; Male; Middle Aged; Prospective Studies; ROC Curve

2019
Decrease of 5-hydroxymethylcytosine is associated with progression of hepatocellular carcinoma through downregulation of TET1.
    PloS one, 2013, Volume: 8, Issue:5

    Topics: 5-Methylcytosine; Animals; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Cytosine; Diethylnitrosamine; Dioxygenases; Disease Progression; DNA Methylation; DNA-Binding Proteins; Down-Regulation; Female; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Middle Aged; Mixed Function Oxygenases; Prognosis; Proto-Oncogene Proteins; Rats, Wistar

2013
Association of 5-methylcytosine and 5-hydroxymethylcytosine with mitochondrial DNA content and clinical and biochemical parameters in hepatocellular carcinoma.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: 5-Methylcytosine; Adolescent; Adult; Aged; Aged, 80 and over; Carcinoma, Hepatocellular; Cytosine; DNA, Mitochondrial; Female; Humans; Liver Cirrhosis; Liver Neoplasms; Male; Middle Aged; Risk Factors; Tumor Burden; Young Adult

2013
Hsa-miR-520d induces hepatoma cells to form normal liver tissues via a stemness-mediated process.
    Scientific reports, 2014, Jan-24, Volume: 4

    Topics: 5-Methylcytosine; Animals; Carcinoma, Hepatocellular; Cell Dedifferentiation; Cell Differentiation; Cell Line, Tumor; Cell Movement; Cytosine; DNA Methylation; ELAV Proteins; ELAV-Like Protein 2; Gene Expression Regulation, Neoplastic; Gene Transfer Techniques; Genetic Vectors; HEK293 Cells; Homeodomain Proteins; Humans; Lentivirus; Liver; Liver Neoplasms; Metabolomics; Mice; MicroRNAs; Nanog Homeobox Protein; Neoplasm Transplantation; Neoplastic Stem Cells; Octamer Transcription Factor-3; Pluripotent Stem Cells; Proto-Oncogene Proteins c-myc; RNA Interference; RNA, Small Interfering; Serum Albumin; Serum Albumin, Human; Telomerase; Transplantation, Heterologous; Tumor Suppressor Protein p53

2014
High expression of 5-hydroxymethylcytosine and isocitrate dehydrogenase 2 is associated with favorable prognosis after curative resection of hepatocellular carcinoma.
    Journal of experimental & clinical cancer research : CR, 2014, Apr-10, Volume: 33

    Topics: 5-Methylcytosine; Carcinoma, Hepatocellular; Cytosine; DNA Methylation; Female; Hepatectomy; Humans; Isocitrate Dehydrogenase; Kaplan-Meier Estimate; Liver Neoplasms; Male; Middle Aged; Multivariate Analysis; Neoplasm Recurrence, Local; Prognosis; Proportional Hazards Models; Retrospective Studies; Treatment Outcome

2014
RRHP: a tag-based approach for 5-hydroxymethylcytosine mapping at single-site resolution.
    Genome biology, 2014, Sep-24, Volume: 15, Issue:9

    Topics: 5-Methylcytosine; Cytosine; DNA Methylation; Gene Library; High-Throughput Nucleotide Sequencing; Humans; Liver Neoplasms; Molecular Sequence Annotation; Sequence Analysis, DNA

2014
Integrated analyses of DNA methylation and hydroxymethylation reveal tumor suppressive roles of ECM1, ATF5, and EOMES in human hepatocellular carcinoma.
    Genome biology, 2014, Dec-03, Volume: 15, Issue:12

    Topics: 5-Methylcytosine; Activating Transcription Factors; Carcinoma, Hepatocellular; Cell Line, Tumor; Comparative Genomic Hybridization; Cytosine; DNA Methylation; Epigenesis, Genetic; Extracellular Matrix Proteins; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Humans; Liver Neoplasms; Molecular Sequence Data; Promoter Regions, Genetic; Sequence Analysis, DNA; T-Box Domain Proteins

2014
Whole-genome DNA methylation and hydroxymethylation profiling for HBV-related hepatocellular carcinoma.
    International journal of oncology, 2016, Volume: 49, Issue:2

    Topics: 5-Methylcytosine; Carcinoma, Hepatocellular; DNA Methylation; Genome-Wide Association Study; Hepatitis B virus; Hepatitis B, Chronic; Humans; Liver Neoplasms; Promoter Regions, Genetic

2016
The decreased N
    Biochemical and biophysical research communications, 2016, Nov-04, Volume: 480, Issue:1

    Topics: 3T3-L1 Cells; 5-Methylcytosine; Adenine; Animals; Chromatography, High Pressure Liquid; DNA; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Mice; Mice, Inbred C57BL; Neoplasms; Tandem Mass Spectrometry

2016
Quantification of 5-methylcytosine and 5-hydroxymethylcytosine in genomic DNA from hepatocellular carcinoma tissues by capillary hydrophilic-interaction liquid chromatography/quadrupole TOF mass spectrometry.
    Clinical chemistry, 2013, Volume: 59, Issue:5

    Topics: 5-Methylcytosine; Biomarkers; Carcinoma, Hepatocellular; Chromatography, Liquid; Cytosine; DNA Methylation; DNA, Neoplasm; Humans; Limit of Detection; Liver Neoplasms; Sequence Analysis, DNA; Tandem Mass Spectrometry

2013
3-D DNA methylation phenotypes correlate with cytotoxicity levels in prostate and liver cancer cell models.
    BMC pharmacology & toxicology, 2013, Feb-11, Volume: 14

    Topics: 5-Methylcytosine; Antibodies, Monoclonal; Antineoplastic Agents; Apoptosis; Azacitidine; Cell Line, Tumor; Cell Survival; Cytidine; DNA Methylation; Humans; Liver Neoplasms; Male; Phenotype; Prostatic Neoplasms

2013
Genome-wide hypomethylation in hepatocellular carcinogenesis.
    Cancer research, 2001, May-15, Volume: 61, Issue:10

    Topics: 5-Methylcytosine; Adult; Aged; Carcinoma, Hepatocellular; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Methyltransferase 3A; DNA, Neoplasm; Female; Genome, Human; Humans; Isoenzymes; Liver Neoplasms; Long Interspersed Nucleotide Elements; Male; Middle Aged; Reverse Transcriptase Polymerase Chain Reaction; Transcription, Genetic

2001
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