5-methylcytosine has been researched along with Leukemia, Myeloid, Acute in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 12 (70.59) | 24.3611 |
| 2020's | 5 (29.41) | 2.80 |
| Authors | Studies |
|---|---|
| Ganguly, S; He, C; Karpus, J; Li, Z; Shah, S; Shao, J; Smith, J; Wang, S; West-Szymanski, D; Zu, Y | 1 |
| Ganguly, S; He, C; Li, Z; Shah, S; Shao, J; Zu, Y | 2 |
| An, J; Cheng, AX; Jeong, H; Ko, M; López-Moyado, IF; Nakayama, T; Onodera, A; Rao, A; Scott-Browne, J; Yuita, H | 1 |
| Cai, M; Chen, Y; Hong, Y; Li, S; Liu, Y; Wu, X | 1 |
| Arnovitz, S; Chen, J; Chen, P; Dawlaty, M; Elkahloun, AG; Gurbuxani, S; He, C; Hong, GM; Huang, H; Jaenisch, R; Jiang, X; Jin, P; Li, Y; Li, Z; Lin, L; Liu, PP; Mulloy, JC; Neilly, MB; Rowley, JD; Song, CX; Street, C; Sun, M; Szulwach, K; Wang, J; Wunderlich, M; Xu, M; Yang, FC | 1 |
| Amadori, S; Aslanyan, MG; Cilloni, D; da Silva-Coelho, P; de Witte, T; Jansen, JH; Koorenhof-Scheele, TN; Kroeze, LI; Labar, B; Langemeijer, SM; Marie, JP; Marijt, EW; Massop, M; Muus, P; Saglio, G; Stevens-Linders, E; Suciu, S; Tang, R; Tönnissen, E; van de Locht, LT; van der Heijden, A; van der Reijden, BA; van Hoogen, P; Willemze, R | 1 |
| Abdel-Wahab, O; Ahn, J; Aifantis, I; Alkalin, A; Ciminio, L; Dai, Q; Daniels, D; Ferrando, A; Figueroa, ME; Fuks, F; Godley, LA; He, C; Hricik, T; Levine, RL; Li, Y; Licht, JD; Lu, C; Madzo, J; Mason, CE; Melnick, A; Nimer, S; Paietta, E; Patel, J; Pronier, E; Rampal, R; Shih, A; Tallman, JE; Tallman, MS; Thompson, CB; Tosello, V; Tsai, JJ; Vasanthakumar, A; Ward, PS; Zhao, X | 1 |
| Chevassut, T; Cho, IH; Choudhury, SR; Chowdhury, B; Cooper, B; Cui, Y; Irudayaraj, J; Lossie, AC; McGovern, A | 1 |
| Chen, BJ; Dresser, K; Hutchinson, LM; Lee, PJ; Magotra, M; Sakhdari, A; Tomaszewicz, K; Woda, BA | 1 |
| Abboud, CN; Baty, JD; Cashen, AF; DiPersio, JF; Duncavage, EJ; Fehniger, TA; Fronick, CC; Fulton, RS; Ghobadi, A; Graubert, TA; Hantel, A; Heath, SE; Jacoby, MA; Janke, MR; Khan, N; Knoebel, RW; Lee, YS; Ley, TJ; Link, DC; Luber, K; Miller, CA; O'Laughlin, M; Oh, ST; Petti, AA; Pusic, I; Romee, R; Schroeder, MA; Stock, W; Stockerl-Goldstein, KE; Sukhanova, MJ; Tandon, B; Tomasson, MH; Uy, GL; Vij, R; Walter, MJ; Wartman, LD; Welch, JS; Westervelt, P; Wilson, RK | 1 |
| Ahn, JS; Ahn, SY; Choi, SH; Jang, JH; Jung, CW; Jung, SH; Kim, DD; Kim, HJ; Kim, SH; Kim, YK; Lee, JJ; Lee, SS; Michael, S; Minden, MD; Moon, JH; Park, HJ; Sohn, SK; Won, JH; Yang, DH | 1 |
| Agarwal, S; An, J; Aravind, L; Bandukwala, HS; Ganetzky, R; Huang, Y; Jankowska, AM; Ko, M; Koh, KP; Lamperti, ED; Liu, XS; Maciejewski, JP; Pape, UJ; Rao, A; Tahiliani, M | 1 |
| Abdel-Wahab, O; Bhagwat, N; Choe, SE; Delwel, R; Fantin, VR; Fernandez, HF; Figueroa, ME; Godley, LA; Levine, RL; Li, Y; Licht, JD; Liu, W; Löwenberg, B; Lu, C; Melnick, A; Paietta, E; Patel, J; Peeters, JK; Shih, A; Sun, Z; Tallman, MS; Thompson, CB; Valk, PJ; Vasanthakumar, A; Ward, PS; Wolniak, K | 1 |
| Bohlander, SK; Bultmann, S; Dufour, A; Herold, T; Kakadia, PM; Konstandin, N; Ksienzyk, B; Leonhardt, H; Mulaw, M; Schneider, F; Schneider, S; Spiekermann, K; Szwagierczak, A | 1 |
| Claus, R; Dahl, E; Galm, O; Hielscher, T; Jost, E; Plass, C; Sonnet, M; Wilop, S | 1 |
| Abdel-Wahab, O; Fantin, V; Godley, LA; Kohrt, HE; Levine, R; Medeiros, BC; Pollyea, DA; Schenkein, D; Straley, K; Vasanthakumar, A; Zehnder, J; Zhang, B | 1 |
1 trial(s) available for 5-methylcytosine and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
TP53 and Decitabine in Acute Myeloid Leukemia and Myelodysplastic Syndromes.
Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Azacitidine; Biomarkers, Tumor; Bone Marrow; Decitabine; Exome; Female; Humans; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Myelodysplastic Syndromes; Prospective Studies; Risk Factors; Survival Rate; Tumor Suppressor Protein p53 | 2016 |
16 other study(ies) available for 5-methylcytosine and Leukemia, Myeloid, Acute
| Article | Year |
|---|---|
Cell-free DNA 5-hydroxymethylcytosine is an emerging marker of acute myeloid leukemia.
Topics: 5-Methylcytosine; Cell-Free Nucleic Acids; Epigenomics; Humans; Leukemia, Myeloid, Acute | 2022 |
Classification of Acute Myeloid Leukemia by Cell-Free DNA 5-Hydroxymethylcytosine.
Topics: 5-Methylcytosine; Humans; Leukemia, Myeloid, Acute; Proto-Oncogene Proteins | 2023 |
Inducible disruption of
Topics: 5-Methylcytosine; Animals; Dioxygenases; DNA Methylation; Euchromatin; Heterochromatin; Leukemia, Myeloid, Acute; Mammals; Mice | 2023 |
Cell-free DNA 5-hydroxymethylcytosine is highly sensitive for MRD assessment in acute myeloid leukemia.
Topics: 5-Methylcytosine; Cell-Free Nucleic Acids; DNA Methylation; Humans; Leukemia, Myeloid, Acute | 2023 |
m5C methylation modification guides the prognostic value and immune landscapes in acute myeloid leukemia.
Topics: 5-Methylcytosine; Humans; Immunotherapy; Leukemia, Myeloid, Acute; Methylation; Prognosis; Tumor Microenvironment | 2023 |
TET1 plays an essential oncogenic role in MLL-rearranged leukemia.
Topics: 5-Methylcytosine; Chromatin Immunoprecipitation; Chromatography, Liquid; Cytosine; DNA-Binding Proteins; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Histone-Lysine N-Methyltransferase; Homeodomain Proteins; Humans; Immunoblotting; Leukemia, Myeloid, Acute; Microarray Analysis; Mixed Function Oxygenases; Myeloid Ecotropic Viral Integration Site 1 Protein; Myeloid-Lymphoid Leukemia Protein; Neoplasm Proteins; Oligonucleotide Array Sequence Analysis; Proto-Oncogene Proteins; Signal Transduction; Tandem Mass Spectrometry | 2013 |
Clinical and biological impact of TET2 mutations and expression in younger adult AML patients treated within the EORTC/GIMEMA AML-12 clinical trial.
Topics: 5-Methylcytosine; Adolescent; Adult; Animals; Chlorocebus aethiops; Clinical Trials as Topic; COS Cells; Cytosine; Dioxygenases; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; DNA-Binding Proteins; Female; Gene Expression Regulation, Leukemic; Humans; Isocitrate Dehydrogenase; Kaplan-Meier Estimate; Leukemia, Myeloid, Acute; Male; Multicenter Studies as Topic; Mutation; Neoplasm Proteins; Prognosis; Prospective Studies; Proto-Oncogene Proteins; Recombinant Fusion Proteins; RNA, Messenger; RNA, Neoplasm; Transfection; Young Adult | 2014 |
DNA hydroxymethylation profiling reveals that WT1 mutations result in loss of TET2 function in acute myeloid leukemia.
Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cytosine; Dioxygenases; DNA-Binding Proteins; Enhancer Elements, Genetic; Gene Expression Regulation, Neoplastic; Hematopoiesis; Humans; Leukemia, Myeloid, Acute; Mice, Knockout; Mutation; Promoter Regions, Genetic; Protein Binding; Proto-Oncogene Proteins; Sequence Analysis, DNA; WT1 Proteins | 2014 |
The hypomethylating agent Decitabine causes a paradoxical increase in 5-hydroxymethylcytosine in human leukemia cells.
Topics: 5-Methylcytosine; Azacitidine; Catalytic Domain; Chromatography, High Pressure Liquid; CpG Islands; Cytosine; Decitabine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Enzyme-Linked Immunosorbent Assay; HL-60 Cells; Humans; Immunohistochemistry; Leukemia, Myeloid, Acute; MCF-7 Cells; Microscopy, Fluorescence; Mixed Function Oxygenases; Protein Binding; Proto-Oncogene Proteins; Spectrometry, Fluorescence; Tandem Mass Spectrometry | 2015 |
Immunohistochemical loss of 5-hydroxymethylcytosine expression in acute myeloid leukaemia: relationship to somatic gene mutations affecting epigenetic pathways.
Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; DNA Mutational Analysis; Epigenesis, Genetic; Female; High-Throughput Nucleotide Sequencing; History, 17th Century; Humans; Immunohistochemistry; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation | 2016 |
5-Hydroxymethylcytosine correlates with epigenetic regulatory mutations, but may not have prognostic value in predicting survival in normal karyotype acute myeloid leukemia.
Topics: 5-Methylcytosine; Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Dioxygenases; Disease Progression; Disease-Free Survival; DNA Mutational Analysis; DNA-Binding Proteins; Enzyme-Linked Immunosorbent Assay; Epigenesis, Genetic; Female; Genetic Predisposition to Disease; Humans; Isocitrate Dehydrogenase; Kaplan-Meier Estimate; Karyotype; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Phenotype; Predictive Value of Tests; Proportional Hazards Models; Proto-Oncogene Proteins; Recurrence; Time Factors; Treatment Outcome; Young Adult | 2017 |
Impaired hydroxylation of 5-methylcytosine in myeloid cancers with mutant TET2.
Topics: 5-Methylcytosine; Animals; Biocatalysis; Cell Differentiation; Cell Line; CpG Islands; Dioxygenases; DNA Methylation; DNA-Binding Proteins; DNA, Neoplasm; Humans; Hydroxylation; Leukemia, Myeloid, Acute; Mice; Mice, Inbred C57BL; Mutant Proteins; Mutation; Myelodysplastic Syndromes; Proto-Oncogene Proteins | 2010 |
Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation.
Topics: 5-Methylcytosine; Cell Differentiation; Dioxygenases; DNA Methylation; DNA-Binding Proteins; GATA1 Transcription Factor; Gene Regulatory Networks; Humans; Hydroxylation; Isocitrate Dehydrogenase; Leukemia, Myeloid, Acute; MDS1 and EVI1 Complex Locus Protein; Mutation; Myeloid Cells; Phenotype; Proto-Oncogene Proteins; Proto-Oncogenes; Transcription Factors | 2010 |
Genomic 5-hydroxymethylcytosine levels correlate with TET2 mutations and a distinct global gene expression pattern in secondary acute myeloid leukemia.
Topics: 5-Methylcytosine; Cytosine; Dioxygenases; DNA-Binding Proteins; Gene Expression Profiling; Humans; In Situ Hybridization, Fluorescence; Leukemia, Myeloid, Acute; Mutation; Proto-Oncogene Proteins | 2011 |
A systematic comparison of quantitative high-resolution DNA methylation analysis and methylation-specific PCR.
Topics: 5-Methylcytosine; 5' Untranslated Regions; Aged; Aged, 80 and over; DNA Methylation; Female; High-Throughput Nucleotide Sequencing; Humans; Inhibitor of Differentiation Proteins; Leukemia, Myeloid, Acute; Male; Mass Spectrometry; Middle Aged; Polymerase Chain Reaction; Sensitivity and Specificity; Sequence Analysis, DNA; Young Adult | 2012 |
2-Hydroxyglutarate in IDH mutant acute myeloid leukemia: predicting patient responses, minimal residual disease and correlations with methylcytosine and hydroxymethylcytosine levels.
Topics: 5-Methylcytosine; Aged; Aged, 80 and over; Female; Glutarates; Humans; Isocitrate Dehydrogenase; Leukemia, Myeloid, Acute; Male; Mutation; Neoplasm, Residual; Prognosis; Remission Induction; Treatment Outcome | 2013 |