5-methylcytosine has been researched along with Disease Exacerbation in 29 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (3.45) | 29.6817 |
| 2010's | 23 (79.31) | 24.3611 |
| 2020's | 5 (17.24) | 2.80 |
| Authors | Studies |
|---|---|
| Chen, C; Chen, S; Chen, Z; Hu, X; Hu, Y; Lu, M; Pan, B; Shen, X; Shi, X; Sun, X; Tong, X; Xue, X | 1 |
| Chen, L; Hou, P; Li, K; Su, J; Sun, J; Wang, Y; Yan, C; Zhao, J; Zhou, M | 1 |
| Chen, G; Chen, L; Cheng, H; Deng, T; Fan, Y; Gong, P; Niu, X; Tian, Y; Wang, P; Wang, W; Xiao, H; Yang, L; Yang, Y; Yuan, J; Zhang, J; Zhang, P; Zhang, W; Zhang, X | 1 |
| Argueta, C; Fetahu, IS; Liu, H; Ma, D; Rabidou, K; Shi, YG; Smith, M; Wu, F | 1 |
| Bassis, CM; Evans, MC; Feldman, EL; Figueroa-Romero, C; Guo, K; Hur, J; McDermott, AJ; Mikhail, KA; Murdock, BJ; O'Brien, PD; Paez-Colasante, X; Pawlowski, KD; Savelieff, MG; Taubman, GF | 1 |
| Ali, M; Coleman, PD; Del Sol, A; Delvaux, E; Eijssen, LMT; Hoffmann, P; Hurlemann, R; Iatrou, A; Jessen, F; Kawalia, A; Kenis, G; Kleineidam, L; Lardenoije, R; Leber, M; Luck, T; Lunnon, K; Maier, W; Mastroeni, D; Mill, J; Pishva, E; Ramirez, A; Riedel-Heller, S; Roubroeks, JAY; Rutten, BPF; Smith, AR; Smith, RG; van den Hove, DLA; Wagner, H; Wagner, M | 1 |
| Battaglia-Hsu, SF; Chen, B; Feng, J; Gong, C; Guo, D; Guo, T; Li, Z; Liu, P; Liu, Z; Wang, H; Wu, P; Xiao, Y; Yao, Y | 1 |
| Allen, EG; Barwick, BG; Castellino, RC; Chen, J; Chen, L; Conneely, KN; Jin, P; Johnson, ND; Kang, Y; Kenney, AM; Kim, H; Li, J; Li, Y; Liao, X; Lin, L; McSwain, L; Robinson, MH; Shu, Q; Van Meir, EG; Vertino, PM; Yuan, X; Zhang, Z; Zhao, J; Zhu, D | 1 |
| Dinulescu, DM; Getchell, CR; Gupta, M; Hasselblatt, KT; Hirsch, MS; Kaplan, SJ; Ko, JY; Lee, JJ; Li, W; Lian, CG; Liu, JF; MacDonald, LA; Malik, A; Matulonis, UA; McCarthy, ET; Medina, JE; Murphy, GF; Ohman, AW; Sasamoto, N; Shafrir, A; Terry, KL; Tucker, DW; Xu, S; Zhang, H | 1 |
| Chandra, D; Deka, R; Manivannan, P; Mishra, P; Pati, HP; Saxena, R; Singh, J; Tyagi, S | 1 |
| Chen, H; Duan, X; Gan, L; Jaypaul, H; Liu, N; Liu, X; Makamure, JT; Ming, Z; Wang, X; Zhang, S; Zhu, K | 1 |
| Li, X; Lian, CG; Liu, F; Liu, X; Qiu, L; Tu, P; Wang, Y; Xiao, C; Yi, S | 1 |
| Betz, BL; Brown, NA; Cascalho, M; Cooke, A; Davis, A; El Kadi, N; Hassan, KA; Kalemkerian, GP; Korkaya, H; Vadnala, V; Wang, L | 1 |
| Bizet, M; Bonvin, E; Calonne, E; Fuks, F; Larue, L; Luciani, F; Marine, JC; Nittner, D; Petit, V; Putmans, P; Radaelli, E; Santagostino, SF; Singh, NK | 1 |
| Gambichler, T; Sand, M; Skrygan, M | 1 |
| Bian, XW; Bie, P; Chen, X; Cui, Y; Liu, C; Liu, L; Qian, C; Shan, J; Shen, J; Wu, L; Xia, F; Xu, Y; Yang, Z | 1 |
| Meehan, RR; Moggs, JG; Thomson, JP; Wolf, CR | 1 |
| Adany, R; Balazs, M; Ecsedi, SI; Herceg, Z; Hernandez-Vargas, H; Lima, SC | 1 |
| Coppieters, N; Curtis, MA; Dieriks, BV; Dragunow, M; Faull, RL; Lill, C | 1 |
| Amini, M; Hossein-nezhad, A; Keshtkar, A; Larijani, B; Maghbooli, Z | 1 |
| Gambichler, T; Mamali, K; Moritz, R; Mucke, M; Patsinakidis, N; Skrygan, M; Stockfleth, E; Stücker, M | 1 |
| Fujimura, T; Hayashizaki, Y; Homma, Y; Inoue, S; Misawa, A; Suzuki, T; Takagi, K; Takahashi, S; Takayama, K; Urano, T | 1 |
| Fraitag, S; Hohl, D; Pavlova, O | 1 |
| Chen, L; Gong, F; Guo, Y; Jin, J; Li, R; Ma, RZ; Niu, Y; Shi, X; Zhang, L; Zhang, X | 1 |
| Abner, EL; Ellison, EM; Lovell, MA | 1 |
| Ahn, JS; Ahn, SY; Choi, SH; Jang, JH; Jung, CW; Jung, SH; Kim, DD; Kim, HJ; Kim, SH; Kim, YK; Lee, JJ; Lee, SS; Michael, S; Minden, MD; Moon, JH; Park, HJ; Sohn, SK; Won, JH; Yang, DH | 1 |
| Gu, Y; Hou, W; Li, F; Li, H; Li, Q; Lin, W; Song, Y; Sun, H; Yang, B; Zhang, F; Zhang, L | 1 |
| Albasanz, JL; Barrachina, M; Blanch, M; Ferrer, I; Martín, M; Pereira-Veiga, T; Pérez-Navarro, E; Tyebji, S; Villar-Menéndez, I | 1 |
| Bell, WC; Frost, AR; Grizzle, WE; Heimburger, DC; Johanning, GL; Niveleau, A; Oelschlager, D; Piyathilake, CJ; Weiss, H | 1 |
1 review(s) available for 5-methylcytosine and Disease Exacerbation
| Article | Year |
|---|---|
Epigenetic profiles as defined signatures of xenobiotic exposure.
Topics: 5-Methylcytosine; Animals; Carcinogens; Chemical Safety; Chromatin; Cytosine; Disease Progression; DNA Methylation; Epigenesis, Genetic; Epigenomics; Genetic Markers; Genome; Humans; Transcriptome; Xenobiotics | 2014 |
28 other study(ies) available for 5-methylcytosine and Disease Exacerbation
| Article | Year |
|---|---|
NSUN2 modified by SUMO-2/3 promotes gastric cancer progression and regulates mRNA m5C methylation.
Topics: 5-Methylcytosine; Aged; Amino Acid Sequence; Base Sequence; Carcinogenesis; Cell Line, Tumor; Cell Movement; Cell Nucleus; Cell Proliferation; Disease Progression; Female; Gene Expression Regulation, Neoplastic; Humans; Male; Methylation; Methyltransferases; Middle Aged; Models, Biological; Mutation; Neoplasm Invasiveness; Neoplasm Metastasis; Prognosis; Protein Stability; RNA, Messenger; Small Ubiquitin-Related Modifier Proteins; Stomach Neoplasms; Subcellular Fractions; Sumoylation; Ubiquitins | 2021 |
Cell-free DNA 5-hydroxymethylcytosine profiles of long non-coding RNA genes enable early detection and progression monitoring of human cancers.
Topics: 5-Methylcytosine; Cell-Free Nucleic Acids; Disease Progression; Early Detection of Cancer; Humans; Neoplasms; RNA, Long Noncoding | 2021 |
Crosstalk between 5-methylcytosine and N
Topics: 5-Methylcytosine; Apoptosis; Carcinoma, Hepatocellular; Cell Line, Tumor; Disease Progression; G2 Phase Cell Cycle Checkpoints; Humans; Liver Neoplasms; Pharmacogenetics | 2023 |
Epigenetic signatures of methylated DNA cytosine in Alzheimer's disease.
Topics: 5-Methylcytosine; Aged; Alzheimer Disease; Biomarkers; Cytosine; Disease Progression; DNA; DNA Methylation; Epigenesis, Genetic; Epigenomics; Female; Humans; Male; Neurons | 2019 |
Temporal evolution of the microbiome, immune system and epigenome with disease progression in ALS mice.
Topics: 5-Methylcytosine; Amyotrophic Lateral Sclerosis; Animals; Bacteria; Brain; Disease Progression; Epigenome; Feces; Female; Gastrointestinal Microbiome; Immune System; Inflammation; Leukocytes; Male; Mice, Inbred C57BL; Mice, Transgenic; Myeloid Cells; Phenotype; Phylogeny; Superoxide Dismutase-1; Time Factors | 2019 |
Alzheimer's disease-associated (hydroxy)methylomic changes in the brain and blood.
Topics: 5-Methylcytosine; Age of Onset; Aged; Aged, 80 and over; Alzheimer Disease; Brain Chemistry; Disease Progression; DNA Methylation; Epigenesis, Genetic; Female; Humans; Intracellular Signaling Peptides and Proteins; Male; Oxytocin; Receptors, Nicotinic; Temporal Lobe | 2019 |
LINC00662 promotes hepatocellular carcinoma progression via altering genomic methylation profiles.
Topics: 3' Untranslated Regions; 5-Methylcytosine; Adenosylhomocysteinase; Adult; Carcinogenesis; Carcinoma, Hepatocellular; Cell Line, Tumor; Disease Progression; DNA Methylation; Down-Regulation; Gene Expression Regulation, Neoplastic; Genome, Human; Humans; Liver Neoplasms; Methionine Adenosyltransferase; Proteolysis; RNA, Long Noncoding; RNA, Messenger; S-Adenosylhomocysteine; S-Adenosylmethionine; Survival Analysis; Ubiquitin; Up-Regulation | 2020 |
Ten-eleven translocation protein 1 modulates medulloblastoma progression.
Topics: 5-Methylcytosine; Animals; Biomarkers, Tumor; Computational Biology; CpG Islands; Databases, Nucleic Acid; Disease Models, Animal; Disease Progression; Disease Susceptibility; DNA Methylation; Epigenesis, Genetic; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Medulloblastoma; Mice; Mice, Transgenic; Mixed Function Oxygenases; Nucleotide Motifs; Prognosis; Proto-Oncogene Proteins | 2021 |
Epigenetic Reprogramming Strategies to Reverse Global Loss of 5-Hydroxymethylcytosine, a Prognostic Factor for Poor Survival in High-grade Serous Ovarian Cancer.
Topics: 5-Methylcytosine; Animals; Cell Survival; Cellular Reprogramming; Combined Modality Therapy; Cystadenocarcinoma, Serous; Dioxygenases; Disease Models, Animal; Disease Progression; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Mice; Neoplasm Grading; Ovarian Neoplasms; Prognosis; Proto-Oncogene Proteins; Recurrence; Survival Analysis; Xenograft Model Antitumor Assays | 2018 |
Utility of 5-Methylcytosine Immunohistochemical Staining to Assess Global DNA Methylation and Its Prognostic Impact in MDS Patients
Topics: 5-Methylcytosine; Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Case-Control Studies; Disease Progression; DNA Methylation; Female; Follow-Up Studies; Genome, Human; Humans; Immunoenzyme Techniques; Male; Middle Aged; Myelodysplastic Syndromes; Prognosis; Prospective Studies; Retrospective Studies; Risk Factors; Staining and Labeling; Survival Rate; Young Adult | 2017 |
Ten-eleven Translocation-2 Regulates DNA Hydroxymethylation Status and Psoriasiform Dermatitis Progression in Mice.
Topics: 5-Methylcytosine; Aminoquinolines; Animals; Case-Control Studies; Cell Differentiation; Cell Proliferation; Chemokine CXCL1; Dioxygenases; Disease Models, Animal; Disease Progression; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Female; Humans; Imiquimod; Interferon-gamma; Interleukin-17; Mice, Inbred BALB C; Proto-Oncogene Proteins; Psoriasis; Skin; Time Factors | 2018 |
Loss of 5-Hydroxymethylcytosine Is an Epigenetic Biomarker in Cutaneous T-Cell Lymphoma.
Topics: 5-Methylcytosine; Apoptosis; Biomarkers, Tumor; Carcinogenesis; CD4-Positive T-Lymphocytes; Cell Line, Tumor; Disease Progression; Epigenesis, Genetic; Female; Humans; Keratinocytes; Lymphoma, T-Cell, Cutaneous; Male; Mycosis Fungoides; Neoplasm Staging; Prognosis; Skin Neoplasms; Survival Analysis | 2018 |
The EGFR T790M Mutation Is Acquired through AICDA-Mediated Deamination of 5-Methylcytosine following TKI Treatment in Lung Cancer.
Topics: 5-Methylcytosine; Aged; Cell Line, Tumor; Cytidine Deaminase; Deamination; Disease Progression; ErbB Receptors; Female; Humans; Hydrolysis; Lung Neoplasms; Male; Mass Spectrometry; Methylation; Middle Aged; Mutation; NF-kappa B; Polymerase Chain Reaction; Protein-Tyrosine Kinases | 2018 |
TET2-Dependent Hydroxymethylome Plasticity Reduces Melanoma Initiation and Progression.
Topics: 5-Methylcytosine; Animals; Dioxygenases; Disease Progression; DNA-Binding Proteins; DNA, Neoplasm; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Melanoma, Experimental; Mice; Mice, Inbred C57BL; Mice, Inbred DBA; Mice, Knockout; Mice, Transgenic; Monomeric GTP-Binding Proteins; Proto-Oncogene Proteins; Rats; Skin Neoplasms | 2019 |
Loss of 5-hydroxymethylcytosine and ten-eleven translocation 2 protein expression in malignant melanoma.
Topics: 5-Methylcytosine; Biomarkers, Tumor; Cytosine; Dioxygenases; Disease Progression; DNA-Binding Proteins; Epigenomics; Humans; Melanoma; Paraffin Embedding; Proto-Oncogene Proteins; Skin Neoplasms; Translocation, Genetic | 2013 |
Decrease of 5-hydroxymethylcytosine is associated with progression of hepatocellular carcinoma through downregulation of TET1.
Topics: 5-Methylcytosine; Animals; Blotting, Western; Carcinoma, Hepatocellular; Cell Line, Tumor; Cytosine; Diethylnitrosamine; Dioxygenases; Disease Progression; DNA Methylation; DNA-Binding Proteins; Down-Regulation; Female; Humans; Immunohistochemistry; Kaplan-Meier Estimate; Liver Neoplasms; Liver Neoplasms, Experimental; Male; Middle Aged; Mixed Function Oxygenases; Prognosis; Proto-Oncogene Proteins; Rats, Wistar | 2013 |
Transposable hypomethylation is associated with metastatic capacity of primary melanomas.
Topics: 5-Methylcytosine; Adult; CpG Islands; Disease Progression; Disease-Free Survival; DNA Methylation; DNA Transposable Elements; Epigenesis, Genetic; Female; Genetic Predisposition to Disease; Humans; Kaplan-Meier Estimate; Long Interspersed Nucleotide Elements; Male; Melanoma; Middle Aged; Phenotype; Proportional Hazards Models; Risk Factors; Skin Neoplasms; Time Factors; Treatment Outcome; Young Adult | 2013 |
Global changes in DNA methylation and hydroxymethylation in Alzheimer's disease human brain.
Topics: 5-Methylcytosine; Aged; Aged, 80 and over; Alzheimer Disease; Astrocytes; Cytosine; Disease Progression; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression; Genetic Markers; Humans; Male; Microglia; Middle Aged; Neurons; Parahippocampal Gyrus | 2014 |
Global DNA methylation as a possible biomarker for diabetic retinopathy.
Topics: 5-Methylcytosine; Analytic Sample Preparation Methods; Biomarkers; Case-Control Studies; Chromatography, High Pressure Liquid; Diabetes Mellitus, Type 2; Diabetic Retinopathy; Disease Progression; DNA Methylation; Female; Humans; Hydrolysis; Iran; Leukocytes; Male; Middle Aged; Predictive Value of Tests; Risk Factors; Up-Regulation; Vitreoretinopathy, Proliferative | 2015 |
Decreased expression of ten-eleven translocation 2 protein is associated with progressive disease and death in patients with mycosis fungoides.
Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Biomarkers; Dioxygenases; Disease Progression; DNA-Binding Proteins; Female; Humans; Isocitrate Dehydrogenase; Male; Middle Aged; Mycosis Fungoides; Proto-Oncogene Proteins; Skin Neoplasms | 2016 |
TET2 repression by androgen hormone regulates global hydroxymethylation status and prostate cancer progression.
Topics: 5-Methylcytosine; Aged; Androgens; Animals; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Chromatin Immunoprecipitation; Cytosine; Dioxygenases; Disease Progression; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; HEK293 Cells; Hepatocyte Nuclear Factor 3-alpha; Humans; Hydroxylation; Immunohistochemistry; Male; Mice, Inbred BALB C; MicroRNAs; Middle Aged; Neoplasm Transplantation; Prostatic Neoplasms; Proto-Oncogene Proteins; Receptors, Androgen; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Sequence Analysis, RNA; TOR Serine-Threonine Kinases | 2015 |
5-Hydroxymethylcytosine Expression in Proliferative Nodules Arising within Congenital Nevi Allows Differentiation from Malignant Melanoma.
Topics: 5-Methylcytosine; Adult; Analysis of Variance; Biopsy, Needle; Cohort Studies; Diagnosis, Differential; Disease Progression; Dysplastic Nevus Syndrome; Epigenesis, Genetic; Female; Gene Expression Regulation, Neoplastic; Humans; Immunohistochemistry; Male; Melanoma; Melanoma, Cutaneous Malignant; Nevus, Pigmented; Real-Time Polymerase Chain Reaction; Reproducibility of Results; Retrospective Studies; Skin Neoplasms | 2016 |
Epigenetic silencing of TET2 and TET3 induces an EMT-like process in melanoma.
Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Line, Tumor; Chromatin Immunoprecipitation; Decitabine; Dioxygenases; Disease Progression; DNA (Cytosine-5-)-Methyltransferases; DNA Demethylation; DNA Methylation; DNA Methyltransferase 3A; DNA-Binding Proteins; Down-Regulation; Epigenesis, Genetic; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Humans; Male; Melanoma; Mice; Mice, Inbred C57BL; Microscopy, Fluorescence; Promoter Regions, Genetic; Proto-Oncogene Proteins; RNA, Small Interfering; Transforming Growth Factor beta1; Xenograft Model Antitumor Assays | 2017 |
Multiregional analysis of global 5-methylcytosine and 5-hydroxymethylcytosine throughout the progression of Alzheimer's disease.
Topics: 5-Methylcytosine; Aged; Aged, 80 and over; Alzheimer Disease; Brain; Disease Progression; Epigenesis, Genetic; Female; Gas Chromatography-Mass Spectrometry; Humans; Male | 2017 |
5-Hydroxymethylcytosine correlates with epigenetic regulatory mutations, but may not have prognostic value in predicting survival in normal karyotype acute myeloid leukemia.
Topics: 5-Methylcytosine; Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Dioxygenases; Disease Progression; Disease-Free Survival; DNA Mutational Analysis; DNA-Binding Proteins; Enzyme-Linked Immunosorbent Assay; Epigenesis, Genetic; Female; Genetic Predisposition to Disease; Humans; Isocitrate Dehydrogenase; Kaplan-Meier Estimate; Karyotype; Leukemia, Myeloid, Acute; Male; Middle Aged; Mutation; Phenotype; Predictive Value of Tests; Proportional Hazards Models; Proto-Oncogene Proteins; Recurrence; Time Factors; Treatment Outcome; Young Adult | 2017 |
Evaluation of global DNA hypomethylation in human prostate cancer and prostatic intraepithelial neoplasm tissues by immunohistochemistry.
Topics: 5-Methylcytosine; Aged; Aged, 80 and over; Disease Progression; DNA Methylation; Humans; Immunohistochemistry; Male; Middle Aged; Neoplasm Grading; Prognosis; Prostate; Prostatic Intraepithelial Neoplasia; Prostatic Neoplasms; Reproducibility of Results; Sensitivity and Specificity | 2013 |
Increased 5-methylcytosine and decreased 5-hydroxymethylcytosine levels are associated with reduced striatal A2AR levels in Huntington's disease.
Topics: 5-Methylcytosine; 5' Untranslated Regions; Adult; Aged; Aged, 80 and over; Animals; Corpus Striatum; Cytosine; Disease Models, Animal; Disease Progression; DNA Methylation; Down-Regulation; Female; Gene Expression Regulation; Humans; Huntingtin Protein; Huntington Disease; Male; Mice; Mice, Transgenic; Middle Aged; Nerve Tissue Proteins; Putamen; Receptor, Adenosine A2A | 2013 |
Altered global methylation of DNA: an epigenetic difference in susceptibility for lung cancer is associated with its progression.
Topics: 5-Methylcytosine; Antibodies, Monoclonal; Bronchi; Carcinoma, Squamous Cell; Cytosine; Disease Progression; Disease Susceptibility; DNA Methylation; DNA, Neoplasm; Fluorescent Antibody Technique, Indirect; Genetic Predisposition to Disease; Humans; Hyperplasia; Lung Neoplasms; Precancerous Conditions; Respiratory Mucosa; Smoking | 2001 |