Compounds > 5-methylcytosine
Page last updated: 2024-08-24

5-methylcytosine and Cell Transformation, Neoplastic

5-methylcytosine has been researched along with Cell Transformation, Neoplastic in 35 studies

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-199010 (28.57)18.7374
1990's6 (17.14)18.2507
2000's1 (2.86)29.6817
2010's12 (34.29)24.3611
2020's6 (17.14)2.80

Authors

AuthorsStudies
Boudra, R; Lian, CG; Ramsey, MR; Schmults, CD; Wang, D; Wells, M; Woappi, Y; Xu, S1
Capell, BC1
Balaiah, M; Mani, S; Ramasamy, D; Rao, AKDM; Sundersingh, S; Thangarajan, R; Veluswami, S; Vittal Rangan, A1
An, J; Ko, M1
Cui, W; Hostetter, G; Huang, Z; Jin, SG; Johnson, J; Lau, KH; Pfeifer, GP1
Achreja, A; Agarwal, B; Aluri, S; Baddour, J; Banerjee, D; Bartenstein, M; Batra, S; Bhagat, P; Bhagat, TD; Bhattacharyya, S; Choudhary, GS; Dawlaty, M; Giricz, O; Goggins, M; Gordon-Mitchell, S; Greally, J; Guerrero, PA; Gupta, S; Kwak, C; Maitra, A; Nagrath, D; Patel, B; Pradhan, K; Sahu, S; Sohal, D; Steidl, U; Suzuki, M; Verma, A; Von Ahrens, D; Yang, L; Yu, Y; Zhao, H; Zou, Y1
Chorley, BN; Corton, JC; Gunewardena, S; Klaassen, CD; Liu, J; Yue Cui, J1
Fondufe-Mittendorf, Y; Gripshover, T; Rea, M1
Cai, C; Chen, LY; Kang, JX; Xie, AM; Ye, XX; Zhang, JJ; Zhang, LJ; Zhang, LT1
Hunter, JM; Lempiäinen, H; Meehan, RR; Moggs, JG; Müller, A; Terranova, R; Thomson, JP1
Hornick, JL; Mason, EF1
Bhagat, TD; Bhattacharyya, S; Campbell, N; Christopeit, M; Godley, L; Greally, JM; Maitra, A; Mazdo, J; Nischal, S; Parekh, S; Steidl, U; Suzuki, M; Vasanthakumar, A; Verma, A; Yu, Y1
Ling, ZQ; Wu, YC1
An, J; Han, JA; Ko, M1
Blanquart, C; Deshayes, S; Fonteneau, JF; Grégoire, M; Guilly, MN; Hulin, P; Le Martelot, V; Liddell, C; Nader, JS; Ouacher, A; Pouliquen, DL; Robard, M; Roulois, D1
Abdel-Wahab, O; Aifantis, I; Cimmino, L; Levine, RL1
Aburatani, H; Asaoka, Y; Ijichi, H; Koike, K; Kudo, Y; Nagae, G; Tateishi, K; Yamamoto, K; Yamamoto, S; Yoshida, H1
Bai, F; Guan, KL; Ling, ZQ; Liu, J; Liu, Y; Ma, SH; Xiong, Y; Xu, ZD; Yang, H; Ye, D; Zhang, JY; Zhu, HG1
Azrad, M; Brill, I; Grizzle, WE; Jhala, D; Jhala, N; Kabagambe, EK; Macaluso, M; Niveleau, A; Piyathilake, CJ1
Jones, PA; Riggs, AD1
Donaghue, TP; Frost, P; Kerbel, RS; Liteplo, RG1
Chiswell, DJ; Gillespie, DA; Searle, S; Wyke, JA1
Doerfler, W1
Diala, ES; Hoffman, RM1
Doerfler, W; Renz, D; Vardimon, L1
Magee, PN; Nyce, J; Weinhouse, S1
Little, M; Wainwright, B1
Coetzee, GA; Eversole-Cire, P; Gonzales, FA; Hustad, CM; Jones, PA; Rideout, WM; Spruck, CH1
Heby, O1
Bakin, AV; Curran, T1
Dubeau, L; Ehrlich, M; Narayan, A; Qu, G; Yu, MC1
Jones, PA; Rideout, WM; Shen, JC; Spruck, CH; Tsai, YC1
Cecchini, E; Citti, L; Durante, M; Geri, C; Natali, L; Nuti Ronchi, V; Parenti, R1
Breznik, T; Butel, JS; Cohen, JC; Gama-Sosa, MA; Medina, D1
Goldstein, S; Shmookler Reis, RJ1

Reviews

9 review(s) available for 5-methylcytosine and Cell Transformation, Neoplastic

ArticleYear
Epigenetic Modification of Cytosines in Hematopoietic Differentiation and Malignant Transformation.
    International journal of molecular sciences, 2023, Jan-15, Volume: 24, Issue:2

    Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cell Transformation, Neoplastic; Cytosine; Dioxygenases; DNA; DNA Methylation; Epigenesis, Genetic; Hematologic Diseases; Humans; Mammals; Neoplasms

2023
The role of TET family proteins and 5-hydroxymethylcytosine in human tumors.
    Histology and histopathology, 2014, Volume: 29, Issue:8

    Topics: 5-Methylcytosine; Cell Transformation, Neoplastic; Cytosine; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Humans; Neoplasms

2014
Functions of TET Proteins in Hematopoietic Transformation.
    Molecules and cells, 2015, Volume: 38, Issue:11

    Topics: 5-Methylcytosine; Animals; Cell Transformation, Neoplastic; Cytosine; Dioxygenases; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Gene Expression Regulation, Leukemic; Genes, Tumor Suppressor; Hematologic Neoplasms; Hematopoiesis; Humans; Leukemia, Lymphoid; Leukemia, Myeloid; Mice; Oxidation-Reduction

2015
TET family proteins and their role in stem cell differentiation and transformation.
    Cell stem cell, 2011, Sep-02, Volume: 9, Issue:3

    Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cell Transformation, Neoplastic; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Gene Expression Regulation, Developmental; Hematologic Neoplasms; Humans; Mixed Function Oxygenases; Myeloid Cells; Proto-Oncogene Proteins; Stem Cells

2011
5-methylcytosine, gene regulation, and cancer.
    Advances in cancer research, 1983, Volume: 40

    Topics: 5-Methylcytosine; Animals; Azacitidine; Base Sequence; Carcinogens; Cell Transformation, Neoplastic; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Replication; Fibroblasts; Gene Expression Regulation; Humans; Models, Biological; Muscles; Neoplasms; Oncogenes

1983
DNA methylation--a regulatory signal in eukaryotic gene expression.
    The Journal of general virology, 1981, Volume: 57, Issue:Pt 1

    Topics: 5-Methylcytosine; Adenoviridae; Animals; Bacteriophages; Base Sequence; Cell Transformation, Neoplastic; Cell Transformation, Viral; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA, Viral; Gene Expression Regulation; Genes, Viral; Herpesviridae; Insect Viruses; Methylation; Polyomavirus; Retroviridae; Simian virus 40

1981
5-Methylcytosine depletion during tumour development: an extension of the miscoding concept.
    British journal of cancer, 1983, Volume: 48, Issue:4

    Topics: 5-Methylcytosine; Alkylation; Amino Acid Metabolism, Inborn Errors; Animals; Carcinogens; Cell Transformation, Neoplastic; Choline Deficiency; Cytosine; DNA; DNA Repair; Gene Expression Regulation; Humans; Methylation; Methyltransferases; Models, Genetic; Neoplasms; Oncogenes; Rats; Tyrosine; Vitamin B 6 Deficiency

1983
DNA methylation and polyamines in embryonic development and cancer.
    The International journal of developmental biology, 1995, Volume: 39, Issue:5

    Topics: 5-Methylcytosine; Animals; Cell Transformation, Neoplastic; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Replication; Embryonic and Fetal Development; Female; Gene Expression Regulation, Developmental; Humans; Male; Methylation; Mice; Mutagenesis; Neoplasms; Nucleic Acid Conformation; Oogenesis; Polyamines; Replication Origin; Spermatogenesis; Transcription, Genetic

1995
Methylation, mutation and cancer.
    BioEssays : news and reviews in molecular, cellular and developmental biology, 1992, Volume: 14, Issue:1

    Topics: 5-Methylcytosine; Animals; Cell Transformation, Neoplastic; Cytosine; Deamination; DNA; DNA, Neoplasm; Female; Genes, p53; Genetic Diseases, Inborn; Humans; Male; Methylation; Mutation; Neoplasms; Neoplasms, Experimental; Vertebrates

1992

Other Studies

26 other study(ies) available for 5-methylcytosine and Cell Transformation, Neoplastic

ArticleYear
Regulation of 5-Hydroxymethylcytosine by TET2 Contributes to Squamous Cell Carcinoma Tumorigenesis.
    The Journal of investigative dermatology, 2022, Volume: 142, Issue:5

    Topics: 5-Methylcytosine; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Humans; Mice; Proto-Oncogene Proteins; Skin Neoplasms

2022
Loss of TET2 Tips the Scales Toward Tumorigenesis.
    The Journal of investigative dermatology, 2022, Volume: 142, Issue:5

    Topics: 5-Methylcytosine; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Humans; Proto-Oncogene Proteins

2022
Locus-Specific Enrichment Analysis of 5-Hydroxymethylcytosine Reveals Novel Genes Associated with Breast Carcinogenesis.
    Cells, 2022, 09-20, Volume: 11, Issue:19

    Topics: 5-Methylcytosine; Breast Neoplasms; Cell Transformation, Neoplastic; Cytosine; DNA, Intergenic; Female; Humans; Untranslated Regions

2022
Deficiency of the Polycomb Protein RYBP and TET Methylcytosine Oxidases Promotes Extensive CpG Island Hypermethylation and Malignant Transformation.
    Cancer research, 2023, 08-01, Volume: 83, Issue:15

    Topics: 5-Methylcytosine; Animals; Carcinoma, Squamous Cell; Cell Transformation, Neoplastic; CpG Islands; DNA; DNA Methylation; Humans; Lung Neoplasms; Mice; Oxidoreductases; Polycomb Repressive Complex 1; Repressor Proteins

2023
Lactate-mediated epigenetic reprogramming regulates formation of human pancreatic cancer-associated fibroblasts.
    eLife, 2019, 11-01, Volume: 8

    Topics: 5-Methylcytosine; Animals; Cancer-Associated Fibroblasts; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Cell Proliferation; Cell Transformation, Neoplastic; Cellular Reprogramming; DNA Methylation; Epigenesis, Genetic; Humans; Ketoglutaric Acids; Lactic Acid; Mesenchymal Stem Cells; Mice; Neoplasm Invasiveness; Pancreatic Neoplasms; Receptors, CXCR4; Stromal Cells; Transcriptome

2019
Transplacental arsenic exposure produced 5-methylcytosine methylation changes and aberrant microRNA expressions in livers of male fetal mice.
    Toxicology, 2020, 04-15, Volume: 435

    Topics: 5-Methylcytosine; Animals; Arsenites; Cell Transformation, Neoplastic; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Regulation, Developmental; Gene Expression Regulation, Neoplastic; Gestational Age; Liver; Liver Neoplasms; Male; Maternal Exposure; Mice, Inbred C3H; MicroRNAs; Pregnancy; Sodium Compounds

2020
Selective inhibition of CTCF binding by iAs directs TET-mediated reprogramming of 5-hydroxymethylation patterns in iAs-transformed cells.
    Toxicology and applied pharmacology, 2018, 01-01, Volume: 338

    Topics: 5-Methylcytosine; Arsenic; CCCTC-Binding Factor; Cell Transformation, Neoplastic; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Humans; Mixed Function Oxygenases; Promoter Regions, Genetic; Proto-Oncogene Proteins

2018
Quantification of the sixth DNA base 5-hydroxymethylcytosine in colorectal cancer tissue and C-26 cell line.
    Bioanalysis, 2013, Volume: 5, Issue:7

    Topics: 5-Methylcytosine; Cell Line, Tumor; Cell Transformation, Neoplastic; Chromatography, Liquid; Colorectal Neoplasms; Cytosine; DNA Methylation; DNA, Neoplasm; Female; Humans; Male; Middle Aged; Tandem Mass Spectrometry

2013
Dynamic changes in 5-hydroxymethylation signatures underpin early and late events in drug exposed liver.
    Nucleic acids research, 2013, Volume: 41, Issue:11

    Topics: 5-Methylcytosine; Animals; Carcinogens; Cell Transformation, Neoplastic; Cytochrome P-450 Enzyme System; Cytosine; DNA Methylation; Epigenesis, Genetic; Genetic Markers; Liver; Male; Mice; Oligonucleotide Array Sequence Analysis; Phenobarbital; Promoter Regions, Genetic; Transcriptome

2013
Succinate dehydrogenase deficiency is associated with decreased 5-hydroxymethylcytosine production in gastrointestinal stromal tumors: implications for mechanisms of tumorigenesis.
    Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 2013, Volume: 26, Issue:11

    Topics: 5-Methylcytosine; Biomarkers, Tumor; Cell Transformation, Neoplastic; Cytosine; DNA Mutational Analysis; Down-Regulation; Electron Transport Complex II; Exons; Gastrointestinal Stromal Tumors; Gene Expression Regulation, Neoplastic; Genetic Predisposition to Disease; Humans; Immunohistochemistry; Membrane Proteins; Mutation; Phenotype; Proto-Oncogene Proteins c-kit; Receptor, Platelet-Derived Growth Factor alpha; Succinate Dehydrogenase

2013
Genome-wide hydroxymethylation tested using the HELP-GT assay shows redistribution in cancer.
    Nucleic acids research, 2013, Volume: 41, Issue:16

    Topics: 5-Methylcytosine; Animals; Cell Line, Tumor; Cell Transformation, Neoplastic; Cytosine; DNA, Neoplasm; Gene Expression; Genome, Human; Genomics; Glycosyltransferases; Humans; Mice; Pancreatic Neoplasms; Polymerase Chain Reaction

2013
Characterization of preneoplastic and neoplastic rat mesothelial cell lines: the involvement of TETs, DNMTs, and 5-hydroxymethylcytosine.
    Oncotarget, 2016, Jun-07, Volume: 7, Issue:23

    Topics: 5-Methylcytosine; Animals; Asbestos, Crocidolite; Biomarkers, Tumor; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cell Transformation, Neoplastic; Cyclin-Dependent Kinase Inhibitor p16; Cyclin-Dependent Kinase Inhibitor p18; DNA (Cytosine-5-)-Methyltransferases; DNA Methyltransferase 3A; Epithelial Cells; Epithelium; Humans; Karyotype; Lung Neoplasms; Mesothelioma; Mesothelioma, Malignant; Mixed Function Oxygenases; Precancerous Conditions; Proto-Oncogene Proteins; Rats; Rats, Inbred F344

2016
Loss of 5-hydroxymethylcytosine is accompanied with malignant cellular transformation.
    Cancer science, 2012, Volume: 103, Issue:4

    Topics: 5-Methylcytosine; Cell Line, Tumor; Cell Transformation, Neoplastic; Colorectal Neoplasms; Cytosine; DNA Methylation; DNA-Binding Proteins; Gene Knockdown Techniques; Humans; Mixed Function Oxygenases; Mutation; Neoplasms; Proto-Oncogene Proteins; Stomach Neoplasms

2012
Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation.
    Oncogene, 2013, Jan-31, Volume: 32, Issue:5

    Topics: 5-Methylcytosine; Animals; Biomarkers, Tumor; Cell Transformation, Neoplastic; Cytosine; Dioxygenases; DNA-Binding Proteins; Down-Regulation; Humans; Hydroxylation; Mice; Mixed Function Oxygenases; Neoplasms; Proto-Oncogene Proteins

2013
Mandatory fortification with folic acid in the United States is not associated with changes in the degree or the pattern of global DNA methylation in cells involved in cervical carcinogenesis.
    Cancer biomarkers : section A of Disease markers, 2006, Volume: 2, Issue:6

    Topics: 5-Methylcytosine; Adult; Antibodies, Monoclonal; Cell Transformation, Neoplastic; DNA Methylation; Edible Grain; Female; Folic Acid; Food, Fortified; Humans; Immunohistochemistry; Middle Aged; United States; Uterine Cervical Dysplasia; Uterine Cervical Neoplasms

2006
Selection of strongly immunogenic "tum-" variants from tumors at high frequency using 5-azacytidine.
    The Journal of experimental medicine, 1984, May-01, Volume: 159, Issue:5

    Topics: 5-Methylcytosine; Animals; Antigens, Neoplasm; Azacitidine; Cell Transformation, Neoplastic; Cytosine; DNA; Ethyl Methanesulfonate; Mammary Neoplasms, Experimental; Mast-Cell Sarcoma; Methylnitronitrosoguanidine; Mice; Mice, Inbred A; Mice, Inbred DBA; Mice, Nude; Mutagens; Neoplasm Transplantation; Phenotype

1984
Analysis of the variations in proviral cytosine methylation that accompany transformation and morphological reversion in a line of Rous sarcoma virus-infected Rat-1 cells.
    Nucleic acids research, 1984, Jul-11, Volume: 12, Issue:13

    Topics: 5-Methylcytosine; Animals; Avian Sarcoma Viruses; Azacitidine; Base Sequence; Cell Line; Cell Transformation, Neoplastic; Cytosine; DNA Restriction Enzymes; DNA, Viral; Methylation; Rats; Transcription, Genetic

1984
DNA methylation levels in normal and chemically-transformed mouse 3T3 cells.
    Biochemical and biophysical research communications, 1982, Feb-26, Volume: 104, Issue:4

    Topics: 5-Methylcytosine; Animals; Base Composition; Benzo(a)pyrene; Benzopyrenes; Cell Line; Cell Transformation, Neoplastic; Chromatography, High Pressure Liquid; Cytosine; DNA; Methylation; Methylcholanthrene; Mice

1982
Can DNA methylation regulate gene expression?
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1983, Volume: 84

    Topics: 5-Methylcytosine; Adenoviruses, Human; Animals; Cell Line; Cell Transformation, Neoplastic; Cytosine; DNA; DNA Restriction Enzymes; DNA, Viral; Female; Genes; Humans; Methylation; Oocytes; Operon; Transcription, Genetic; Xenopus

1983
Methylation and p16: suppressing the suppressor.
    Nature medicine, 1995, Volume: 1, Issue:7

    Topics: 5-Methylcytosine; Carrier Proteins; Cell Transformation, Neoplastic; Cocarcinogenesis; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Cytosine; DNA; Gene Expression Regulation; Genes, Tumor Suppressor; Genomic Imprinting; Humans; Methylation; Models, Genetic; Neoplasms

1995
Progressive increases in the methylation status and heterochromatinization of the myoD CpG island during oncogenic transformation.
    Molecular and cellular biology, 1994, Volume: 14, Issue:9

    Topics: 5-Methylcytosine; Animals; Base Sequence; Cell Cycle; Cell Line; Cell Transformation, Neoplastic; Cytosine; DNA Primers; DNA Replication; Enhancer Elements, Genetic; Gene Expression Regulation; Heterochromatin; Humans; Methylation; Mice; Molecular Sequence Data; MyoD Protein; Promoter Regions, Genetic; Restriction Mapping

1994
Role of DNA 5-methylcytosine transferase in cell transformation by fos.
    Science (New York, N.Y.), 1999, Jan-15, Volume: 283, Issue:5400

    Topics: 5-Methylcytosine; Acetylation; Animals; Cell Size; Cell Transformation, Neoplastic; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genes, fos; Histone Deacetylase Inhibitors; Histones; Hydroxamic Acids; Proto-Oncogene Proteins c-fos; Rats; Transcription, Genetic; Transfection

1999
Satellite DNA hypomethylation vs. overall genomic hypomethylation in ovarian epithelial tumors of different malignant potential.
    Mutation research, 1999, Jan-25, Volume: 423, Issue:1-2

    Topics: 5-Methylcytosine; Carcinoma; Cell Transformation, Neoplastic; Centromere; Chromosomes, Human, Pair 1; Chromosomes, Human, Pair 16; Cytosine; DNA Methylation; DNA, Neoplasm; DNA, Satellite; Female; Humans; Ovarian Neoplasms

1999
5-azacytidine-induced tumorous transformation and DNA hypomethylation in Nicotiana tissue cultures.
    Developmental genetics, 1989, Volume: 10, Issue:4

    Topics: 5-Methylcytosine; Azacitidine; Cell Transformation, Neoplastic; Cells, Cultured; Cytosine; Deoxyribonuclease HpaII; Deoxyribonucleases, Type II Site-Specific; DNA; Electrophoresis, Agar Gel; Methylation; Plant Tumors; Thymidine; Time Factors

1989
Mammary preneoplasia and tumorigenesis in the BALB/c mouse: structure and modification of mouse mammary tumor virus DNA sequences.
    Virus research, 1987, Volume: 7, Issue:1

    Topics: 5-Methylcytosine; 9,10-Dimethyl-1,2-benzanthracene; Animals; Cell Transformation, Neoplastic; Cytosine; DNA Restriction Enzymes; DNA, Viral; Female; Genes, Viral; Mammary Glands, Animal; Mammary Neoplasms, Experimental; Mammary Tumor Virus, Mouse; Methylation; Mice; Mice, Inbred BALB C; Precancerous Conditions; Recombination, Genetic; Virus Replication

1987
Methylation patterns in the gene for the alpha subunit of chorionic gonadotropin are inherited with variable fidelity in clonal lineages of human fibroblasts.
    Nucleic acids research, 1985, Oct-11, Volume: 13, Issue:19

    Topics: 5-Methylcytosine; Cell Transformation, Neoplastic; Cells, Cultured; Chorionic Gonadotropin; Cytosine; DNA Replication; Gene Expression Regulation; Genes; Humans; Methylation

1985