Compounds > 5-methylcytosine
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5-methylcytosine and Breast Neoplasms

5-methylcytosine has been researched along with Breast Neoplasms in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (11.11)18.2507
2000's5 (18.52)29.6817
2010's10 (37.04)24.3611
2020's9 (33.33)2.80

Authors

AuthorsStudies
Argueta, C; Li, S; Liu, L; Lyu, R; Shen, Y; Tan, L; Xiong, L; Zhu, X1
Chen, C; Chen, CH; Jiang, D; Li, S; Liu, R; Liu, W; Mao, X; Peng, J; Qiu, T; Ren, W; Sun, J; Wen, Y; Wu, K; Wu, Y; Yang, C; Zhou, J; Zhou, Z1
Balaiah, M; Mani, S; Ramasamy, D; Rao, AKDM; Sundersingh, S; Thangarajan, R; Veluswami, S; Vittal Rangan, A1
Chu, C; Gao, X; Jin, Y; Tang, F; Wang, H; Zhang, K; Zhang, W; Zhang, Z; Zhou, J; Zou, L; Zou, Q1
Bai, M; Chen, F; Fan, C; Xue, J; Yu, X; Zhang, J; Zhao, Y1
Chellamuthu, A; Gray, SG1
Balasubramanian, S; Broome, R; Carroll, JS; Chernukhin, I; D'Santos, C; Farcas, AM; Groen, AJ; Jamieson, S; Kishore, K; Mahtey, A; Mao, SQ; Papachristou, EK; Siersbæk, R; Tejedo, CG; Theodorou, V1
Chang, M; Cui, M; Cui, X; Huang, C; Jiang, J; Jin, F; Li, Q; Liang, ZY; Liu, Y; Niu, Y; Qian, J; Sun, L; Tong, WM; Wang, X; Wu, HW; Wu, SL; Yu, X; Yuan, F; Zhang, X1
Bearden, S; Hall, AR; Reiss, K; Rivas, F; Sethi, K; Wang, F; Zahid, OK1
Chen, J; Gustafson, CB; Mustafi, S; Sant, DW; Slingerland, JM; Wang, G1
Bruno, RD; Mollica, PA; Northam, N; Palmer, XL; Reid, JA; Sachs, PC1
Ai, S; Jiang, W; Liu, F; Lu, N; Wu, H; Yin, H; Zhou, Y1
Ala, U; Beringer, G; Brikbak, NJ; Cantley, LC; Ng, C; Pandolfi, PP; Poliseno, L; Richardson, AL; Song, MS; Song, SJ; Webster, K; Yuan, X1
Kocher, JP; Prodduturi, N; Sun, SY; Sun, Z; Thompson, EA1
Chang, HT; Chang, HY; Chen, CC; Chen, CH; Fu, TY; Ger, LP; Huang, JS; Huang, SF; Li, GC; Liou, HH; Pan, HW; Tsai, KW; Tseng, HH; Yeh, MH1
Ai, S; Jiang, W; Liu, F; Yang, Z; Yin, H; Zhou, Y1
Benner, C; Chang, HT; Chen, CH; Chen, SF; Gascon, P; Ger, LP; Hishida, T; Izpisua Belmonte, JC; Jan, CI; Lin, YS; Ma, L; Montserrat, N; Nieh, S; Sancho-Martinez, I; Wu, MZ1
Edamitsu, T; Ito, K; Kawachi, S; Maeno, K; Ogawa, E; Okuyama, R; Takazawa, Y; Uhara, H1
Ambrosone, CB; Choi, JY; Davis, W; Hong, CC; James, SR; Karpf, AR; Link, PA; McCann, SE; Nesline, MK1
Argani, P; Chaux, A; De Marzo, AM; Esopi, DM; Gerber, J; Haffner, MC; Iacobuzio-Donahue, C; Meeker, AK; Nelson, WG; Netto, GJ; Pellakuru, LG; Toubaji, A; Yegnasubramanian, S1
Avila, S; Capella, G; Esteller, M; Fraga, MF; Herman, JG; Paz, MF; Peinado, MA; Pollan, M; Sanchez-Cespedes, M1
Ballestar, E; Cigudosa, JC; Espada, J; Esteller, M; Fraga, MF; Huang, TH; Paz, MF; Valle, L; Wei, S1
Barciszewska, AM; Barciszewska, MZ; Gawronska, I; Murawa, D; Murawa, P; Nowak, S1
Eskelinen, M; Hakkarainen, M; Hiltunen, MO; Jänne, J; Johansson, R; Myöhänen, S; Wahlfors, J1
Denissenko, MF; Pfeifer, GP1
Futscher, BW; Massey-Brown, KS; Rice, JC1
Futscher, BW; Rice, JC1

Reviews

2 review(s) available for 5-methylcytosine and Breast Neoplasms

ArticleYear
The RNA Methyltransferase NSUN2 and Its Potential Roles in Cancer.
    Cells, 2020, 07-22, Volume: 9, Issue:8

    Topics: 5-Methylcytosine; Animals; Breast Neoplasms; Colorectal Neoplasms; Female; Humans; Lung Neoplasms; Methylation; Methyltransferases; Mice; Phylogeny; RNA, Messenger

2020
Formation and repair of DNA lesions in the p53 gene: relation to cancer mutations?
    Environmental and molecular mutagenesis, 1998, Volume: 31, Issue:3

    Topics: 5-Methylcytosine; Animals; Benzo(a)pyrene; Breast Neoplasms; Carcinogens, Environmental; Colonic Neoplasms; Cytosine; Deamination; DNA Adducts; DNA Damage; DNA Mutational Analysis; DNA Repair; Genes, p53; Humans; Lung Neoplasms; Mice; Mutagenesis; Neoplasms; Neoplasms, Radiation-Induced; Selection, Genetic; Skin Neoplasms; Smoking; Tumor Suppressor Protein p53; Ultraviolet Rays

1998

Other Studies

25 other study(ies) available for 5-methylcytosine and Breast Neoplasms

ArticleYear
Regulation of TET2 gene expression and 5mC oxidation in breast cancer cells by estrogen signaling.
    Biochemical and biophysical research communications, 2022, 01-22, Volume: 589

    Topics: 5-Methylcytosine; Breast Neoplasms; Cell Line, Tumor; Dioxygenases; DNA-Binding Proteins; Down-Regulation; Enhancer Elements, Genetic; Estradiol; Estrogen Receptor alpha; Estrogens; Female; Fulvestrant; Gene Expression Regulation, Neoplastic; Humans; Oxidation-Reduction; Protein Binding; Signal Transduction; Transcription, Genetic

2022
YB-1 is a positive regulator of KLF5 transcription factor in basal-like breast cancer.
    Cell death and differentiation, 2022, Volume: 29, Issue:6

    Topics: 5-Methylcytosine; Breast Neoplasms; Cell Line, Tumor; Cell Proliferation; Eye Proteins; Female; Humans; Kruppel-Like Transcription Factors; RNA; RNA, Messenger; Transcription Factors; Y-Box-Binding Protein 1

2022
Locus-Specific Enrichment Analysis of 5-Hydroxymethylcytosine Reveals Novel Genes Associated with Breast Carcinogenesis.
    Cells, 2022, 09-20, Volume: 11, Issue:19

    Topics: 5-Methylcytosine; Breast Neoplasms; Cell Transformation, Neoplastic; Cytosine; DNA, Intergenic; Female; Humans; Untranslated Regions

2022
Values of 5mC, 5hmC, and TET2 for identifying the presence and progression of breast precancerous lesion.
    Journal of clinical laboratory analysis, 2020, Volume: 34, Issue:5

    Topics: 5-Methylcytosine; Adult; Aged; Biomarkers, Tumor; Breast Neoplasms; Dioxygenases; DNA-Binding Proteins; Female; Humans; Immunohistochemistry; Ki-67 Antigen; Middle Aged; Precancerous Conditions; Proto-Oncogene Proteins; Receptor, ErbB-2

2020
Differentiated Visualization of Single-Cell 5-Hydroxymethylpyrimidines with Microfluidic Hydrogel Encoding.
    Journal of the American Chemical Society, 2020, 02-12, Volume: 142, Issue:6

    Topics: 5-Methylcytosine; Breast Neoplasms; Cell Line, Tumor; DNA; Epigenesis, Genetic; Female; Humans; Hydrogels; Microfluidics; Neoplasm Invasiveness; Pentoxyl; Single-Cell Analysis

2020
TET2 is a component of the estrogen receptor complex and controls 5mC to 5hmC conversion at estrogen receptor cis-regulatory regions.
    Cell reports, 2021, 02-23, Volume: 34, Issue:8

    Topics: 5-Methylcytosine; Animals; Breast Neoplasms; Chromatin Assembly and Disassembly; Databases, Genetic; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Enhancer Elements, Genetic; Estrogen Receptor alpha; Estrogen Receptor Antagonists; Female; Fulvestrant; GATA3 Transcription Factor; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Mice, Inbred NOD; Mice, SCID; Xenograft Model Antitumor Assays

2021
Genome-wide 5-Hydroxymethylcytosine Profiling Analysis Identifies MAP7D1 as A Novel Regulator of Lymph Node Metastasis in Breast Cancer.
    Genomics, proteomics & bioinformatics, 2021, Volume: 19, Issue:1

    Topics: 5-Methylcytosine; Breast Neoplasms; Epigenomics; Female; Humans; Lymphatic Metastasis; Microtubule-Associated Proteins; Mixed Function Oxygenases; Proto-Oncogene Proteins

2021
Solid-state nanopore analysis of human genomic DNA shows unaltered global 5-hydroxymethylcytosine content associated with early-stage breast cancer.
    Nanomedicine : nanotechnology, biology, and medicine, 2021, Volume: 35

    Topics: 5-Methylcytosine; Breast Neoplasms; DNA, Neoplasm; Female; Genome, Human; Humans; MCF-7 Cells; Nanopore Sequencing; Neoplasm Staging

2021
Vitamin C promotes apoptosis in breast cancer cells by increasing TRAIL expression.
    Scientific reports, 2018, 03-28, Volume: 8, Issue:1

    Topics: 5-Methylcytosine; Apoptosis; Ascorbic Acid; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Female; Gene Expression Regulation, Neoplastic; Humans; MCF-7 Cells; Receptors, TNF-Related Apoptosis-Inducing Ligand; Sodium-Coupled Vitamin C Transporters; TNF-Related Apoptosis-Inducing Ligand

2018
A 3D bioprinter platform for mechanistic analysis of tumoroids and chimeric mammary organoids.
    Scientific reports, 2019, 05-16, Volume: 9, Issue:1

    Topics: 5-Methylcytosine; Biotechnology; Breast Neoplasms; Carcinogenesis; Cell Line; Cells, Cultured; Female; Humans; Mammary Glands, Human; MCF-7 Cells; Organoids; Printing, Three-Dimensional; Tumor Microenvironment

2019
Amplified electrochemical immunoassay for 5-methylcytosine using a nanocomposite prepared from graphene oxide, magnetite nanoparticles and β-cyclodextrin.
    Mikrochimica acta, 2019, 07-02, Volume: 186, Issue:8

    Topics: 5-Methylcytosine; Alkaline Phosphatase; Avidin; beta-Cyclodextrins; Biosensing Techniques; Breast; Breast Neoplasms; Dendrimers; DNA; Electrochemical Techniques; Female; Graphite; Humans; Immunoassay; Magnetite Nanoparticles; Nanocomposites; Stomach; Stomach Neoplasms

2019
MicroRNA-antagonism regulates breast cancer stemness and metastasis via TET-family-dependent chromatin remodeling.
    Cell, 2013, Jul-18, Volume: 154, Issue:2

    Topics: 5-Methylcytosine; Animals; Breast Neoplasms; Chromatin Assembly and Disassembly; Cytosine; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Mice; Mice, Transgenic; MicroRNAs; Neoplasm Metastasis; Neoplasm Transplantation; Neoplastic Stem Cells; Proto-Oncogene Proteins; RNA Interference; Transplantation, Heterologous

2013
Chromosome X genomic and epigenomic aberrations and clinical implications in breast cancer by base resolution profiling.
    Epigenomics, 2015, Volume: 7, Issue:7

    Topics: 5-Methylcytosine; Breast Neoplasms; Cell Line, Tumor; Chromosomes, Human, X; Databases, Factual; DNA Copy Number Variations; DNA Methylation; Epigenesis, Genetic; Female; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; High-Throughput Nucleotide Sequencing; Humans; Survival Analysis; Transcriptome; X Chromosome Inactivation

2015
Reduction of global 5-hydroxymethylcytosine is a poor prognostic factor in breast cancer patients, especially for an ER/PR-negative subtype.
    Breast cancer research and treatment, 2015, Volume: 153, Issue:1

    Topics: 5-Methylcytosine; Adult; Aged; Breast Neoplasms; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Female; Gene Expression; Humans; Immunohistochemistry; Middle Aged; Mixed Function Oxygenases; Neoplasm Grading; Neoplasm Staging; Prognosis; Protein Transport; Proto-Oncogene Proteins; Receptors, Estrogen; Receptors, Progesterone; Risk Factors; Survival Analysis; Young Adult

2015
A novel electrochemical immunosensor for the quantitative detection of 5-hydroxymethylcytosine in genomic DNA of breast cancer tissue.
    Chemical communications (Cambridge, England), 2015, Oct-07, Volume: 51, Issue:78

    Topics: 5-Methylcytosine; Biosensing Techniques; Breast Neoplasms; Cytosine; DNA, Neoplasm; Female; Humans

2015
Hypoxia Drives Breast Tumor Malignancy through a TET-TNFα-p38-MAPK Signaling Axis.
    Cancer research, 2015, Sep-15, Volume: 75, Issue:18

    Topics: 5-Methylcytosine; Animals; Breast Neoplasms; Cell Hypoxia; Cell Line, Tumor; Chromatin Immunoprecipitation; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Female; Gene Expression Regulation, Neoplastic; Heterografts; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Mice; Mice, Nude; Mixed Function Oxygenases; Molecular Sequence Data; Neoplasm Proteins; Neoplastic Stem Cells; p38 Mitogen-Activated Protein Kinases; Prognosis; Promoter Regions, Genetic; Proto-Oncogene Proteins; Recombinant Fusion Proteins; Retrospective Studies; Signal Transduction; Tumor Necrosis Factor-alpha

2015
5-Hydroxymethylcytosine as a putative marker for erosive adenomatosis of the nipple.
    The Journal of dermatology, 2016, Volume: 43, Issue:5

    Topics: 5-Methylcytosine; Adenoma; Adult; Biomarkers, Tumor; Biopsy, Needle; Breast Neoplasms; Female; Humans; Image-Guided Biopsy; Immunohistochemistry; Magnetic Resonance Imaging; Middle Aged; Nipples

2016
Association between global DNA hypomethylation in leukocytes and risk of breast cancer.
    Carcinogenesis, 2009, Volume: 30, Issue:11

    Topics: 5-Methylcytosine; Adult; Aged; Alcohol Drinking; Breast Neoplasms; Confidence Intervals; Dietary Supplements; DNA Methylation; DNA, Neoplasm; Female; Humans; Leukocytes; Middle Aged; Neoplasm Staging; Odds Ratio; Repetitive Sequences, Nucleic Acid; Risk; Risk Factors; Smoking

2009
Global 5-hydroxymethylcytosine content is significantly reduced in tissue stem/progenitor cell compartments and in human cancers.
    Oncotarget, 2011, Volume: 2, Issue:8

    Topics: 5-Methylcytosine; Adenocarcinoma; Animals; Breast Neoplasms; Carcinoma, Ductal, Breast; Cell Differentiation; Colonic Neoplasms; Cytosine; Down-Regulation; Embryo, Mammalian; Female; Gestational Age; HEK293 Cells; Humans; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Prostatic Neoplasms; Stem Cells

2011
Germ-line variants in methyl-group metabolism genes and susceptibility to DNA methylation in normal tissues and human primary tumors.
    Cancer research, 2002, Aug-01, Volume: 62, Issue:15

    Topics: 5-Methylcytosine; 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenocarcinoma; Breast Neoplasms; Colorectal Neoplasms; CpG Islands; Cystathionine beta-Synthase; Cytosine; DNA Methylation; DNA, Neoplasm; Genetic Predisposition to Disease; Germ-Line Mutation; Humans; Lung Neoplasms; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasms; Oxidoreductases Acting on CH-NH Group Donors

2002
Methyl-CpG binding proteins identify novel sites of epigenetic inactivation in human cancer.
    The EMBO journal, 2003, Dec-01, Volume: 22, Issue:23

    Topics: 5-Methylcytosine; Amino Acid Sequence; Breast Neoplasms; Chromatin; Chromosomal Proteins, Non-Histone; Chromosome Mapping; CpG Islands; DNA Methylation; DNA-Binding Proteins; Female; Humans; Methyl-CpG-Binding Protein 2; Microscopy, Confocal; Molecular Sequence Data; Neoplasms; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; Peptide Fragments; Polymerase Chain Reaction; Promoter Regions, Genetic; Repressor Proteins; Tumor Cells, Cultured

2003
Analysis of 5-methylcytosine in DNA of breast and colon cancer tissues.
    IUBMB life, 2007, Volume: 59, Issue:12

    Topics: 5-Methylcytosine; Adult; Aged; Breast Neoplasms; Colonic Neoplasms; DNA Damage; DNA Methylation; DNA, Neoplasm; Epigenesis, Genetic; Female; Humans; Male; Middle Aged; Oxidation-Reduction

2007
Hypermethylation of calcitonin gene regulatory sequences in human breast cancer as revealed by genomic sequencing.
    International journal of cancer, 1996, Dec-20, Volume: 69, Issue:6

    Topics: 5-Methylcytosine; Breast Neoplasms; Calcitonin; Carcinoma, Ductal, Breast; Carcinoma, Lobular; Chromatography, High Pressure Liquid; Cytosine; DNA Methylation; DNA, Neoplasm; Female; Fibroadenoma; Gene Expression Regulation, Neoplastic; Humans; Regulatory Sequences, Nucleic Acid; Sequence Analysis, DNA

1996
Aberrant methylation of the BRCA1 CpG island promoter is associated with decreased BRCA1 mRNA in sporadic breast cancer cells.
    Oncogene, 1998, Oct-08, Volume: 17, Issue:14

    Topics: 5-Methylcytosine; BRCA1 Protein; Breast Neoplasms; Cell Line; CpG Islands; Cytosine; DNA Methylation; Female; Humans; Polymerase Chain Reaction; Promoter Regions, Genetic; RNA, Messenger; Tumor Cells, Cultured

1998
Transcriptional repression of BRCA1 by aberrant cytosine methylation, histone hypoacetylation and chromatin condensation of the BRCA1 promoter.
    Nucleic acids research, 2000, Sep-01, Volume: 28, Issue:17

    Topics: 5-Methylcytosine; Acetylation; Breast; Breast Neoplasms; Cell Line; Chromatin; CpG Islands; Cytosine; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, BRCA1; Histones; Humans; Precipitin Tests; Promoter Regions, Genetic; Transcription, Genetic; Tumor Cells, Cultured

2000