Compounds > 5-methylcytosine
Page last updated: 2024-08-24

5-methylcytosine and Brain Neoplasms

5-methylcytosine has been researched along with Brain Neoplasms in 27 studies

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.70)18.7374
1990's1 (3.70)18.2507
2000's2 (7.41)29.6817
2010's18 (66.67)24.3611
2020's5 (18.52)2.80

Authors

AuthorsStudies
Ba, Y; Dong, J; Du, J; Gao, X; Hu, S; Ji, H; Jin, J; Liu, Z; Ma, S; Wang, F; Wang, N; Wu, J; Yan, X; Zhang, J; Zhao, H1
Cao, F; Hu, X; Liu, Y; Mao, Q; Xia, L; Xie, D; Yan, X; Yan, Z; Yin, S; Yuan, Y; Zhang, J; Zhang, S1
Barciszewska, AM; Giel-Pietraszuk, M; Naskręt-Barciszewska, M; Perrigue, PM1
Bougras-Cartron, G; Briand, J; Cartron, PF; Nadaradjane, A; Olivier, C; Vallette, FM1
Li, C; Li, P; Li, S; Liu, P; Niu, Y; Tong, WM; Wang, B; Wu, T; Yang, Z; Zhang, J; Zhang, ZW; Zhao, F1
Barciszewska, AM; Barciszewski, J; Belter, A1
Aldape, K; Farooq, H; Glowacka, WK; Jain, H; Kongkham, P; Maimaitiming, A; Mamatjan, Y; Nejad, R; Okura, M; Taylor, MD1
Ding, Y; Fu, R; Guo, SW; Huang, KM; Li, DS; Luo, J; Tang, XJ1
Barderas, R; Campuzano, S; Hardisson, D; Mendiola, M; Montiel, VR; Pedrero, M; Peláez-García, A; Pingarrón, JM; Povedano, E; San Segundo-Acosta, P; Valverde, A; Yáñez-Sedeño, P1
Barciszewska, AM1
Cain, JE; Jayasekara, WSN; St John, JC; Sun, X; Vaghjiani, V1
Astudillo, A; Bayón, GF; Bigot, T; Carella, A; Chiara, MD; Corte-Torres, MD; Fernández, AF; Fraga, MF; García, MG; García-Toraño, E; López, V; Mangas, C; Meléndez, B; Mollejo, M; Pérez, RF; Sáenz-de-Santa-María, I; Santamarina-Ojeda, P; Sierra, M; Tejedor, JR; Urdinguio, RG1
Li, L; Ye, C1
Barciszewska, AM; Naskręt-Barciszewska, MZ; Nowak, S1
Akiyama, T; Ino, Y; Katou, Y; Koyama-Nasu, R; Kozuka-Hata, H; Masuda, K; Morishita, Y; Mukasa, A; Nasu-Nishimura, Y; Ogawa, H; Oyama, M; Saito, N; Sakaguchi, Y; Sato, T; Shirahige, K; Suzuki, T; Takai, H; Todo, T; Toyoshima, C1
Barciszewska, AM; Gurda, D; Głodowicz, P; Naskręt-Barciszewska, MZ; Nowak, S1
Kriaucionis, S; McClellan, M; Schuster-Boeckler, B; Tomkova, M1
Cui, Y; Freeman, JL; Irudayaraj, J; Li, J; Liu, J; Liu, Q; Weng, L; Wirbisky, SE; Yuan, X1
Christensen, BC; Fadul, CE; Houseman, EA; Johnson, KC; King, JE; von Herrmann, KM1
Coyle, B; Lewis, L; Ramsawhook, A; Ruzov, A1
Jiang, Y; Jin, SG; Krex, D; Lu, Q; Pfeifer, GP; Qiu, R; Rauch, TA; Schackert, G; Wang, Y1
Carell, T; Eigenbrod, S; Feiden, W; Globisch, D; Hackner, B; Kraus, TF; Kretzschmar, HA; Müller, M; Münzel, M; Pfaffeneder, T; Schüller, U; Wagner, M; Widmann, D1
Becker, A; Denkhaus, D; Freihoff, D; Freihoff, J; Gessi, M; Hammes, J; Isselstein, LJ; Luxen, D; Müller, T; Pietsch, T; Simon, M; Waha, A; zur Mühlen, A1
Barciszewska, AM; Barciszewska, MZ; Gawronska, I; Keith, G; Nowak, S; Zukiel, R1
Cadieux, B; Ching, TT; Costello, JF; VandenBerg, SR1
Adams, JK; Allan, RG; Cooper, IA; Woodcock, DM1
Baylin, SB; Burger, PC; Gabrielson, E; Herman, JG; Lee, DJ; Mao, L; Merlo, A; Sidransky, D1

Reviews

1 review(s) available for 5-methylcytosine and Brain Neoplasms

ArticleYear
5-hydroxymethylcytosine: a new insight into epigenetics in cancer.
    Cancer biology & therapy, 2014, Volume: 15, Issue:1

    Topics: 5-Methylcytosine; Animals; Brain Neoplasms; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Humans; Leukemia; Mixed Function Oxygenases; Neoplasms; Proto-Oncogene Proteins

2014

Other Studies

26 other study(ies) available for 5-methylcytosine and Brain Neoplasms

ArticleYear
5-Methylcytosine Related LncRNAs Reveal Immune Characteristics, Predict Prognosis and Oncology Treatment Outcome in Lower-Grade Gliomas.
    Frontiers in immunology, 2022, Volume: 13

    Topics: 5-Methylcytosine; Brain Neoplasms; Glioma; Humans; Prognosis; RNA, Long Noncoding; Treatment Outcome; Tumor Microenvironment

2022
Noninvasive detection of brain gliomas using plasma cell-free DNA 5-hydroxymethylcytosine sequencing.
    International journal of cancer, 2023, 04-15, Volume: 152, Issue:8

    Topics: 5-Methylcytosine; Brain; Brain Neoplasms; Glioma; Humans; Isocitrate Dehydrogenase; Mutation

2023
Total DNA Methylation Changes Reflect Random Oxidative DNA Damage in Gliomas.
    Cells, 2019, 09-11, Volume: 8, Issue:9

    Topics: 5-Methylcytosine; 8-Hydroxy-2'-Deoxyguanosine; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Brain Neoplasms; DNA; DNA Damage; DNA Methylation; Female; Glioma; Humans; Male; Middle Aged; Oxidative Stress; Reactive Oxygen Species; Young Adult

2019
Diuron exposure and Akt overexpression promote glioma formation through DNA hypomethylation.
    Clinical epigenetics, 2019, 11-14, Volume: 11, Issue:1

    Topics: 5-Methylcytosine; Animals; Apoptosis Regulatory Proteins; B7-H1 Antigen; Brain Neoplasms; Cell Line, Tumor; Diuron; DNA Methylation; Gene Expression Regulation, Neoplastic; Glioma; Humans; Lectins, C-Type; Mice; Neoplasm Transplantation; Proto-Oncogene Proteins c-akt; Receptors, Cell Surface; Up-Regulation

2019
Characterization of global 5-hydroxymethylcytosine in pediatric posterior fossa ependymoma.
    Clinical epigenetics, 2020, 01-28, Volume: 12, Issue:1

    Topics: 5-Methylcytosine; Adolescent; Brain Neoplasms; Carcinogenesis; Case-Control Studies; Cell Proliferation; Child; Child, Preschool; DNA Methylation; Ependymoma; Epigenomics; Female; Humans; Infant; Infratentorial Neoplasms; Ki-67 Antigen; Male; Prognosis; Proportional Hazards Models

2020
Revealing the epigenetic effect of temozolomide on glioblastoma cell lines in therapeutic conditions.
    PloS one, 2020, Volume: 15, Issue:2

    Topics: 5-Methylcytosine; Brain Neoplasms; Cell Line, Tumor; DNA Methylation; DNA Modification Methylases; Drug Resistance, Neoplasm; Epigenesis, Genetic; Epigenomics; Gene Expression Regulation, Neoplastic; Glioblastoma; Glioma; Humans; Neoplasm Recurrence, Local; Temozolomide

2020
5-Hydroxymethylcytosine preferentially targets genes upregulated in isocitrate dehydrogenase 1 mutant high-grade glioma.
    Acta neuropathologica, 2018, Volume: 135, Issue:4

    Topics: 5-Methylcytosine; Adult; Aged; Brain Neoplasms; Cohort Studies; DNA Methylation; Female; Gene Expression Regulation, Neoplastic; Glioma; Humans; Isocitrate Dehydrogenase; Male; Middle Aged; Neoplasm Grading; RNA, Messenger; Up-Regulation

2018
Ten-eleven translocation 1 regulates methylation of autophagy-related genes in human glioma.
    Neuroreport, 2018, 06-13, Volume: 29, Issue:9

    Topics: 5-Methylcytosine; Autophagy; Brain; Brain Neoplasms; Cell Line, Tumor; DNA Methylation; Glioma; Humans; Mixed Function Oxygenases; Neoplasm Grading; Proto-Oncogene Proteins

2018
Rapid Electrochemical Assessment of Tumor Suppressor Gene Methylations in Raw Human Serum and Tumor Cells and Tissues Using Immunomagnetic Beads and Selective DNA Hybridization.
    Angewandte Chemie (International ed. in English), 2018, 07-02, Volume: 57, Issue:27

    Topics: 5-Methylcytosine; Antibodies; Biosensing Techniques; Brain Neoplasms; Cell Line, Tumor; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; DNA, Single-Stranded; Electrochemical Techniques; Electrodes; Glioblastoma; Humans; Limit of Detection; Nucleic Acid Hybridization; Promoter Regions, Genetic; Tumor Suppressor Proteins

2018
Global DNA demethylation as an epigenetic marker of human brain metastases.
    Bioscience reports, 2018, 10-31, Volume: 38, Issue:5

    Topics: 5-Methylcytosine; Biomarkers, Tumor; Brain Neoplasms; Cell Line, Tumor; DNA Demethylation; DNA Methylation; Epigenesis, Genetic; Humans; Melanoma; Prognosis

2018
The degree of mitochondrial DNA methylation in tumor models of glioblastoma and osteosarcoma.
    Clinical epigenetics, 2018, 12-17, Volume: 10, Issue:1

    Topics: 5-Methylcytosine; Animals; Bone Neoplasms; Brain Neoplasms; Cell Line, Tumor; DNA Copy Number Variations; DNA Methylation; DNA, Mitochondrial; Genotype; Glioblastoma; Humans; Immunoprecipitation; Mice; Mitochondria; Neoplasm Transplantation; Osteosarcoma; Whole Genome Sequencing

2018
Epigenetic downregulation of TET3 reduces genome-wide 5hmC levels and promotes glioblastoma tumorigenesis.
    International journal of cancer, 2020, 01-15, Volume: 146, Issue:2

    Topics: 5-Methylcytosine; Animals; Biopsy; Brain Neoplasms; Carcinogenesis; Cell Line, Tumor; Dioxygenases; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Glioblastoma; Histone Code; Humans; Mice; Prognosis; RNA, Messenger; Survival Analysis; Xenograft Model Antitumor Assays

2020
The degree of global DNA hypomethylation in peripheral blood correlates with that in matched tumor tissues in several neoplasia.
    PloS one, 2014, Volume: 9, Issue:3

    Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Brain Neoplasms; DNA Methylation; Epigenesis, Genetic; Female; Humans; Male; Middle Aged; Neoplasms; Young Adult

2014
5-Hydroxymethylcytosine plays a critical role in glioblastomagenesis by recruiting the CHTOP-methylosome complex.
    Cell reports, 2014, Oct-09, Volume: 9, Issue:1

    Topics: 5-Methylcytosine; Acetylation; Brain Neoplasms; Carcinogenesis; Chromatin; Cytosine; DNA-Binding Proteins; Gene Expression Regulation, Neoplastic; Glioblastoma; HEK293 Cells; Histones; Humans; Methylation; Mixed Function Oxygenases; Nuclear Proteins; Protein-Arginine N-Methyltransferases; Proto-Oncogene Proteins; Repressor Proteins; Transcription Factors; Transcription, Genetic

2014
A New Epigenetic Mechanism of Temozolomide Action in Glioma Cells.
    PloS one, 2015, Volume: 10, Issue:8

    Topics: 5-Methylcytosine; Animals; Antineoplastic Agents, Alkylating; Brain Neoplasms; Cell Line, Tumor; Dacarbazine; DNA; DNA Methylation; Epigenesis, Genetic; Glioma; HeLa Cells; Humans; Oxidative Stress; Rats; Temozolomide

2015
5-hydroxymethylcytosine marks regions with reduced mutation frequency in human DNA.
    eLife, 2016, 05-16, Volume: 5

    Topics: 5-Methylcytosine; Brain Neoplasms; CpG Islands; Databases, Genetic; DNA Methylation; DNA, Neoplasm; Epigenesis, Genetic; Exome Sequencing; Humans; Kidney Neoplasms; Mutation Rate; Myelodysplastic Syndromes; Myeloid Cells

2016
Regulatory landscape and clinical implication of MBD3 in human malignant glioma.
    Oncotarget, 2016, Dec-06, Volume: 7, Issue:49

    Topics: 5-Methylcytosine; Brain Neoplasms; Cell Line, Tumor; Disease-Free Survival; DNA-Binding Proteins; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Glioma; High-Throughput Nucleotide Sequencing; HLA-D Antigens; Humans; MicroRNAs; Oligonucleotide Array Sequence Analysis; Pilot Projects; RNA Interference; RNA, Long Noncoding; RNA, Untranslated; Signal Transduction; Time Factors; Transcription, Genetic; Transfection

2016
5-Hydroxymethylcytosine localizes to enhancer elements and is associated with survival in glioblastoma patients.
    Nature communications, 2016, 11-25, Volume: 7

    Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Brain Neoplasms; DNA Methylation; DNA, Neoplasm; Enhancer Elements, Genetic; Female; Gene Expression Regulation, Neoplastic; Gene Regulatory Networks; Glioblastoma; Humans; Isocitrate Dehydrogenase; Male; Middle Aged; Prefrontal Cortex; Survival Analysis; Transcription Factors

2016
Medulloblastoma and ependymoma cells display increased levels of 5-carboxylcytosine and elevated
    Clinical epigenetics, 2017, Volume: 9

    Topics: 5-Methylcytosine; Brain Neoplasms; Cell Line, Tumor; Cerebellar Neoplasms; Child; Cytosine; Ependymoma; Gene Expression; Humans; Immunohistochemistry; Medulloblastoma; Mixed Function Oxygenases; Proto-Oncogene Proteins; Up-Regulation

2017
5-Hydroxymethylcytosine is strongly depleted in human cancers but its levels do not correlate with IDH1 mutations.
    Cancer research, 2011, Dec-15, Volume: 71, Issue:24

    Topics: 5-Methylcytosine; Animals; Base Sequence; Brain; Brain Neoplasms; Carcinoma, Squamous Cell; Cell Line, Tumor; Chromatography, Liquid; Cytosine; DNA-Binding Proteins; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Immunohistochemistry; Isocitrate Dehydrogenase; Lung Neoplasms; Male; Mice; Mixed Function Oxygenases; Molecular Structure; Mutation; Neoplasms; Proto-Oncogene Proteins; Reverse Transcriptase Polymerase Chain Reaction

2011
Low values of 5-hydroxymethylcytosine (5hmC), the "sixth base," are associated with anaplasia in human brain tumors.
    International journal of cancer, 2012, Oct-01, Volume: 131, Issue:7

    Topics: 5-Methylcytosine; Adolescent; Adult; Aged; Aged, 80 and over; Anaplasia; Astrocytoma; Brain; Brain Neoplasms; Cerebral Cortex; Child; Child, Preschool; Cytosine; DNA; Epigenesis, Genetic; Female; Humans; Isocitrate Dehydrogenase; Male; Middle Aged; Mutation; Young Adult

2012
Nuclear exclusion of TET1 is associated with loss of 5-hydroxymethylcytosine in IDH1 wild-type gliomas.
    The American journal of pathology, 2012, Volume: 181, Issue:2

    Topics: 5-Methylcytosine; Brain Neoplasms; Cell Line, Tumor; Cell Nucleus; Cytosine; Dioxygenases; DNA Methylation; DNA Modification Methylases; DNA Repair Enzymes; DNA-Binding Proteins; Dual-Specificity Phosphatases; Female; Gene Expression Regulation, Enzymologic; Glioblastoma; Glioma; Humans; Immunohistochemistry; Isocitrate Dehydrogenase; Male; Mitogen-Activated Protein Kinase Phosphatases; Mixed Function Oxygenases; Mutation; Proto-Oncogene Proteins; Real-Time Polymerase Chain Reaction; RNA, Messenger; Sequence Analysis, DNA; Subcellular Fractions; Tumor Suppressor Proteins

2012
A simple epigenetic method for the diagnosis and classification of brain tumors.
    Molecular cancer research : MCR, 2004, Volume: 2, Issue:3

    Topics: 5-Methylcytosine; Adult; Aged; Brain Neoplasms; Chromatography, Thin Layer; DNA Methylation; DNA, Neoplasm; Epigenesis, Genetic; Female; Humans; Male; Middle Aged; Oxidative Stress; Reactive Oxygen Species; Sensitivity and Specificity

2004
Genome-wide hypomethylation in human glioblastomas associated with specific copy number alteration, methylenetetrahydrofolate reductase allele status, and increased proliferation.
    Cancer research, 2006, Sep-01, Volume: 66, Issue:17

    Topics: 5-Methylcytosine; Brain Neoplasms; Cell Division; DNA Methylation; DNA, Neoplasm; Genome, Human; Glioblastoma; Humans; Immunohistochemistry; Methylenetetrahydrofolate Reductase (NADPH2); Sequence Deletion

2006
Effect of several inhibitors of enzymatic DNA methylation on the in vivo methylation of different classes of DNA sequences in a cultured human cell line.
    Nucleic acids research, 1983, Jan-25, Volume: 11, Issue:2

    Topics: 5-Methylcytosine; Adenosine; Azacitidine; Brain Neoplasms; Cell Division; Cell Line; Cycloleucine; Cytosine; Deoxyadenosines; DNA; DNA Replication; Ethionine; Homocysteine; Humans; Methylation; Thionucleosides; Tubercidin

1983
5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers.
    Nature medicine, 1995, Volume: 1, Issue:7

    Topics: 5-Methylcytosine; Alleles; Azacitidine; Base Sequence; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Carrier Proteins; Chromosomes, Human, Pair 9; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Cytosine; Decitabine; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Glioma; Head and Neck Neoplasms; Humans; Lung Neoplasms; Methylation; Molecular Sequence Data; Neoplasm Proteins; Neoplasms; Sequence Deletion; Transcription, Genetic; Tumor Cells, Cultured

1995