Page last updated: 2024-08-24

5-methylcytosine and Benign Neoplasms

5-methylcytosine has been researched along with Benign Neoplasms in 118 studies

Research

Studies (118)

Timeframe	Studies, this research(%)	All Research%
pre-1990	6 (5.08)	18.7374
1990's	22 (18.64)	18.2507
2000's	10 (8.47)	29.6817
2010's	63 (53.39)	24.3611
2020's	17 (14.41)	2.80

Authors

Authors	Studies
Chen, L; Hou, P; Li, K; Su, J; Sun, J; Wang, Y; Yan, C; Zhao, J; Zhou, M	1
Li, Y; Liu, Y; Ma, C; Seong, H; Xu, S; Yu, X	1
Cheng, X; Li, Q; Liu, T; Wang, J	1
Besaratinia, A; Caceres, A; Tommasi, S	1
Lu, MJ; Lu, Y	1
Bao, Z; Chu, Q; Jiang, S; Li, L; Lu, J; Su, Y; Xue, C; Zheng, Q	1
Hu, J; Li, DL; Qiu, JG; Wang, ZY; Yuan, H; Zhang, CY	1
An, J; Ko, M	1
Bettegowda, C; Cohen, JD; Curtis, S; Dobbyn, L; Douville, C; Dudley, JC; Ho-Pham, LT; Kinzler, KW; Mattox, A; Nehme, N; Nguyen, TV; Papadopoulos, N; Popoli, M; Ptak, J; Silliman, N; Summers, M; Tran, BNH; Tran, TS; Vogelstein, B; Wang, Y; Zhang, M	1
An, J; Jung, I; Kim, H; Ko, M; Lee, CH	1
Skvortsova, K; Stirzaker, C; Taberlay, P	1
Gao, H; Xu, T	1
Andreou, AZ; Kouidou, S; Malousi, A	1
Blanco, S; Miguel-López, B; Nombela, P	1
Bray, JK; Dawlaty, MM; Maitra, A; Verma, A	1
Fang, J; Gao, Y	1
Guo, W; He, Y; Yu, X; Zhang, M	1
Fernández, AF; Fraga, MF; López, V	1
Olivier, J; Poulos, RC; Wong, JWH	1
Chen, Y; Chua, MS; Diao, J; Dong, B; Hu, J; Jeffrey, SS; Li, W; Liu, B; Ma, L; Quake, SR; So, S; Song, CX; Tian, Z; Wei, Y; Wheeler, A; Xie, D; Xiong, J; Yin, S; Zhang, W; Zhang, Y; Zhou, Z	1
Adhikari, S; Bissonnette, MB; Chen, G; Cui, M; Dai, M; Dong, Y; Hao, H; He, C; Hong, J; Hua, L; Jia, G; Li, W; Liao, Q; Liu, J; Liu, Z; Lu, X; Luo, F; Luo, Z; Meckel, K; Nie, J; Qian, X; Shi, J; Song, Y; Wang, P; Wang, Y; Wei, L; Xu, D; You, L; Yu, S; Yuan, F; Zhang, J; Zhang, T; Zhang, W; Zhang, X; Zhao, Y; Zheng, W	1
Cavalcante, RG; Park, Y; Patil, S; Rozek, LS; Sartor, MA	1
Kriaucionis, S; McClellan, M; Schuster-Böckler, B; Tomkova, M	1
Cech, TR; Costello, JC; Ghandi, M; Huang, FW; Nwumeh, R; Paucek, RD; Stern, JL	1
Aguilar, S; Argilés, G; Arqués, O; Arroyo, AG; Caratù, G; Casanovas, O; Chicote, I; Cuesta-Borrás, E; Dienstmann, R; Eguizabal, C; Gonzalo, P; Landolfi, S; Martínez-Quintanilla, J; Nuciforo, P; Palmer, HG; Prat, A; Puig, I; Ramírez, L; Recio, JA; Seoane, J; Serra, V; Soto, A; Tabernero, J; Tenbaum, SP; Terracciano, L; Villanueva, A; Vivancos, A	1
Adler, GK; Argueta, C; Chen, H; Chen, J; Dong, Z; Duquette, D; Fan, J; Fang, R; Fetahu, IS; Garg, R; Geng, S; Hu, D; Lan, F; Li, Y; Lian, CG; Liu, H; Lv, R; Lynch, L; Mao, F; Murphy, GF; Rabidou, K; Shi, G; Shi, Y; Shi, YG; Tan, L; Wang, M; Wu, D; Wu, F; Xu, S; Xu, Y; Yan, G; Yang, P; Ye, Y; Yin, C; Zhang, L; Zhang, S	1
Pfeifer, GP; Szabó, PE	1
Harjes, U	1
Ecker, JR; Hajkova, P; Luo, C	1
Krais, AM; Meister, M; Park, YJ; Plass, C; Reifenberger, G; Schmeiser, HH	1
Bogdanovic, O; Clark, SJ; Colino-Sanguino, Y; Du, Q; Goodnow, CC; Gould, CM; Horvath, L; Kench, JG; Khoury, A; Lim, SM; Luu, PL; Masle-Farquhar, E; Miosge, LA; Nair, SS; Peters, TJ; Pidsley, R; Polo, JM; Qu, W; Reed, JH; Rubin, MA; Skvortsova, K; Smith, GC; Song, JZ; Stirzaker, C; Zotenko, E	1
Chiu, BC; Stroup, EK; Zeng, C; Zhang, W; Zhang, Z	1
Benner, A; Slynko, A	1
Avraham, S; Caspi, M; Ebenstein, Y; Friedmann-Morvinski, D; Gilat, N; Kariv, R; Lahat, G; Loewenstein, S; Magod, P; Margalit, S; Michaeli, Y; Rosin-Arbesfeld, R; Shahal, T; Zirkin, S	1
De Marzo, AM; Ghosh, S; Haffner, MC; Lotan, TL; Nelson, WG; Pellakuru, LG; Yegnasubramanian, S	1
Błasiak, J; Głowacki, S	1
Wyatt, MD	1
Cadet, J; Wagner, JR	1
Kohli, RM; Zhang, Y	1
Li, L; Ye, C	1
Harrison, DJ; Laird, A; Meehan, RR; Thomson, JP	1
Ling, ZQ; Wu, YC	1
Barciszewska, AM; Naskręt-Barciszewska, MZ; Nowak, S	1
Hahn, MA; Jin, SG; Pfeifer, GP; Xiong, W	1
Delatte, B; Deplus, R; Fuks, F	1
He, C; Shen, L; Song, CX; Zhang, Y	1
Asande, M; Candeloro, P; Cojoc, G; Coluccio, ML; De Vitis, S; Di Fabrizio, E; Limongi, T; Malara, N; Mollace, V; Perozziello, G; Prati, U; Raimondo, R; Raso, C; Renne, M; Roveda, L; Trunzo, V	1
Arab, K; Dienemann, H; Dyckhoff, G; Grummt, I; Herold-Mende, C; Lindroth, AM; Lukanova, A; Lundin, E; Meister, M; Niehrs, C; Oakes, C; Park, YJ; Plass, C; Risch, A; Schäfer, A; Weichenhan, D	1
Huang, Y; Rao, A	1
Chen, T; Chen, Y; Frank, MY; Guo, W; Lian, CG; Liu, C; Liu, R; Murphy, GF; Xu, S; Yan, J	1
Ficz, G; Gribben, JG	1
Chatterjee, A; Morison, IM; Rodger, EJ	1
Cho, IH; Chowdhury, B; Hahn, N; Irudayaraj, J	1
Chen, HF; Chen, SY; Cheng, WC; He, C; Shen, ZJ; Song, C; Teng, SC; Tsai, YP; Wang, HW; Wu, KJ	1
Jansen, JH; Kroeze, LI; van der Reijden, BA	1
Sehgal, M; Shukla, A; Singh, TR	1
Godley, LA; Vasanthakumar, A	1
Berridge, G; Goldin, R; Kessler, BM; Kriaucionis, S; Pugh, KM; Thézénas, ML; Zauri, M	1
Ehrlich, M	1
Barry, WT; Beroukhim, R; Birkbak, NJ; Clark, AP; Culhane, AC; Eklund, AC; Hill, DE; Landini, S; Lim, E; Neupane, M; Schumacher, SE; Silver, DP; Szallasi, Z; Vidal, M	1
Ciesielski, P; Jóźwiak, P; Krześlak, A	1
Collignon, E; Fuks, F; Jeschke, J	1
Bi, C; Cai, B; Liang, J; Yang, F; Zhao, L	1
Jin, WL; Li, WB; Lian, H	1
Du, Q; Guo, H; Hu, Z; Liang, D; Song, W; Wang, H; Xiong, X; Yang, Z; Ye, M; Zhai, S; Zhang, LH; Zhang, X	1
Feinberg, A; Hansen, KD; Li, X; Liu, Y; Salz, T	1
Bhoopatiraju, S; Forster, CL; Freeman, MJ; Hallstrom, TC; Linden, MA; Lu, H; Schmitz, NP; Verneris, MR; Wang, H; Wang, X	1
Chen, Z; Guo, L; He, J; Li, Y; Luo, M; Shi, X	1
Meehan, RR; Thomson, JP	1
Baylin, SB; Cai, Y; Easwaran, H; Li, Y; Luo, J; Wang, Z; Xia, L; Xie, W; Yen, RC; Zhang, YW	1
Carell, T; Globisch, D; Münzel, M	1
Barciszewski, J; Giel-Pietraszuk, M; Markiewicz, WT; Plitta, B	1
Jiang, Y; Jin, SG; Krex, D; Lu, Q; Pfeifer, GP; Qiu, R; Rauch, TA; Schackert, G; Wang, Y	1
Egger, G; Kriegner, A; Pulverer, W; Weinhäusel, A; Wielscher, M	1
Aburatani, H; Asaoka, Y; Ijichi, H; Koike, K; Kudo, Y; Nagae, G; Tateishi, K; Yamamoto, K; Yamamoto, S; Yoshida, H	1
Bai, F; Guan, KL; Ling, ZQ; Liu, J; Liu, Y; Ma, SH; Xiong, Y; Xu, ZD; Yang, H; Ye, D; Zhang, JY; Zhu, HG	1
Shi, YG; Tan, L	1
Guz, J; Jurgowiak, M; Oliński, R	1
Jones, PA; You, JS	1
Kinney, SR; Pradhan, S	1
Avila, S; Capella, G; Esteller, M; Fraga, MF; Herman, JG; Paz, MF; Peinado, MA; Pollan, M; Sanchez-Cespedes, M	1
Johanning, GL; Piyathilake, CJ	1
Avila, S; Esteller, M; Fraga, MF; Guo, M; Herman, JG; Paz, MF; Pollan, M	1
Ballestar, E; Cigudosa, JC; Espada, J; Esteller, M; Fraga, MF; Huang, TH; Paz, MF; Valle, L; Wei, S	1
Dueñas-Gonzalez, A; Revilla Vázquez, A; Sandoval Guerrero, K; Segura-Pacheco, B	1
Walsh, CP; Xu, GL	1
Akhoondi, S; Apostolidou, S; Cepeda, D; Corcoran, M; Dafou, D; Dagnell, M; Dofou, D; Egyhazi, S; Fiegl, H; Grander, D; Hansson, J; Klotz, K; Maljukova, A; Marth, C; Mueller-Holzner, E; Nayer, BN; Nejad, SZ; Nordgren, H; Petersson, F; Reed, SI; Sangfelt, O; Sangfelt, P; Spruck, C; Sun, D; von der Lehr, N; Widschwendter, M; Zali, MR	1
Jones, PA; Riggs, AD	1
Ehrlich, M; Gama-Sosa, MA; Gehrke, CW; Kuo, KC; Oxenhandler, R; Slagel, VA; Trewyn, RW	1
Magee, PN; Nyce, J; Weinhouse, S	1
Cheah, MS; Diala, ES; Hoffman, RM; Rowitch, D	1
Bogenmann, E; Flatau, E; Jones, PA	1
Bhagwat, AS; Yebra, MJ	1
Little, M; Wainwright, B	1
Baylin, SB; Burger, PC; Gabrielson, E; Herman, JG; Lee, DJ; Mao, L; Merlo, A; Sidransky, D	1
Grigg, GW; Holliday, R	1
Counts, JL; Goodman, JI	1
Hennig, UG; von Borstel, RC	1
Jones, PA; Rideout, WM; Spruck, CH	1
Harris, CC	1
Heby, O	1
Jones, PA	1
Venitt, S	1
Bird, AP	1
Gonzalgo, ML; Jones, PA	2
Wachsman, JT	1
Jones, PA; Zingg, JM	1
Laird, PW	1
Holmquist, GP; Pfeifer, GP	1
Jones, PA; Robertson, KD	2
Denissenko, MF; Pfeifer, GP	1
Issa, JP; Kantarjian, HM; Santini, V	1
Costello, JF; Plass, C	1
Jones, PA; Rideout, WM; Shen, JC; Spruck, CH; Tsai, YC	1
Coetzee, GA; Jones, PA; Olumi, AF; Rideout, WM; Spruck, CH	1
Chandler, LA; Jones, PA	1

Reviews

66 review(s) available for 5-methylcytosine and Benign Neoplasms

Article	Year
Ten-eleven translocation proteins (TETs): tumor suppressors or tumor enhancers? Frontiers in bioscience (Landmark edition), 2021, 10-30, Volume: 26, Issue:10 Topics: 5-Methylcytosine; Animals; DNA Methylation; Epigenesis, Genetic; Humans; Mixed Function Oxygenases; Neoplasms; Proto-Oncogene Proteins	2021
DNA Hydroxymethylation in Smoking-Associated Cancers. International journal of molecular sciences, 2022, Feb-28, Volume: 23, Issue:5 Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; Epigenesis, Genetic; Mammals; Neoplasms; Proto-Oncogene Proteins; Smoking	2022
Role of main RNA modifications in cancer: N Signal transduction and targeted therapy, 2022, 04-28, Volume: 7, Issue:1 Topics: 5-Methylcytosine; Adenosine; Humans; Neoplasms; Pseudouridine; RNA Processing, Post-Transcriptional; RNA, Untranslated	2022
Epigenetic Modification of Cytosines in Hematopoietic Differentiation and Malignant Transformation. International journal of molecular sciences, 2023, Jan-15, Volume: 24, Issue:2 Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cell Transformation, Neoplastic; Cytosine; Dioxygenases; DNA; DNA Methylation; Epigenesis, Genetic; Hematologic Diseases; Humans; Mammals; Neoplasms	2023
The DNA methylation landscape in cancer. Essays in biochemistry, 2019, 12-20, Volume: 63, Issue:6 Topics: 5-Methylcytosine; Animals; DNA; DNA Methylation; Epigenomics; Humans; Neoplasms	2019
Hydroxymethylation and tumors: can 5-hydroxymethylation be used as a marker for tumor diagnosis and treatment? Human genomics, 2020, 05-06, Volume: 14, Issue:1 Topics: 5-Methylcytosine; Animals; Biomarkers, Tumor; DNA Methylation; Epigenesis, Genetic; Humans; Neoplasms	2020
The role of m Molecular cancer, 2021, 01-18, Volume: 20, Issue:1 Topics: 5-Methylcytosine; Adenosine; Humans; Neoplasms; Pseudouridine; RNA; RNA Processing, Post-Transcriptional	2021
Roles and Regulations of TET Enzymes in Solid Tumors. Trends in cancer, 2021, Volume: 7, Issue:7 Topics: 5-Methylcytosine; Antineoplastic Combined Chemotherapy Protocols; Carcinogenesis; Clinical Trials as Topic; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Drug Synergism; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Immune Checkpoint Inhibitors; Mixed Function Oxygenases; Mutation; Neoplasms; Proto-Oncogene Proteins; Treatment Outcome	2021
RNA 5-methylcytosine modification and its emerging role as an epitranscriptomic mark. RNA biology, 2021, 10-15, Volume: 18, Issue:sup1 Topics: 5-Methylcytosine; Animals; Humans; Neoplasms; Nervous System Diseases; Protein Biosynthesis; RNA Processing, Post-Transcriptional; Transcriptome	2021
The role of 5-hydroxymethylcytosine in development, aging and age-related diseases. Ageing research reviews, 2017, Volume: 37 Topics: 5-Methylcytosine; Aging; Animals; Cell Differentiation; Cytosine; DNA Methylation; Epigenesis, Genetic; Humans; Neoplasms; Oxidation-Reduction	2017
Dynamic DNA methylation: In the right place at the right time. Science (New York, N.Y.), 2018, 09-28, Volume: 361, Issue:6409 Topics: 5-Methylcytosine; Aging; Animals; Disease; DNA Methylation; Gene Editing; Gene Expression Regulation, Developmental; Humans; Memory; Neoplasms; Single-Cell Analysis; Transcription Factors; Transcription, Genetic	2018
Towards precision medicine: advances in 5-hydroxymethylcytosine cancer biomarker discovery in liquid biopsy. Cancer communications (London, England), 2019, 03-29, Volume: 39, Issue:1 Topics: 5-Methylcytosine; Animals; Biomarkers, Tumor; Cell-Free Nucleic Acids; Epigenomics; Humans; Liquid Biopsy; Neoplasms; Precision Medicine	2019
[Role of 5-hydroxymethylcytosine and TET proteins in epigenetic regulation of gene expression]. Postepy biochemii, 2013, Volume: 59, Issue:1 Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Hematopoiesis; Humans; Mixed Function Oxygenases; Neoplasms; Proto-Oncogene Proteins	2013
Advances in understanding the coupling of DNA base modifying enzymes to processes involving base excision repair. Advances in cancer research, 2013, Volume: 119 Topics: 5-Methylcytosine; Animals; Cell Differentiation; DNA; DNA Damage; DNA Glycosylases; DNA Methylation; DNA Repair; Epigenesis, Genetic; Histones; Humans; Methylation; Neoplasms; Purines; Pyrimidines	2013
TET enzymatic oxidation of 5-methylcytosine, 5-hydroxymethylcytosine and 5-formylcytosine. Mutation research. Genetic toxicology and environmental mutagenesis, 2014, Volume: 764-765 Topics: 5-Methylcytosine; Animals; Cytosine; Dioxygenases; DNA; DNA Methylation; DNA Repair; Humans; Models, Biological; Mutagenesis; Neoplasms; Oxidation-Reduction	2014
TET enzymes, TDG and the dynamics of DNA demethylation. Nature, 2013, Oct-24, Volume: 502, Issue:7472 Topics: 5-Methylcytosine; Animals; Blastocyst; Cellular Reprogramming; Cytosine; DNA Methylation; DNA Repair; DNA Replication; Humans; Neoplasms; Oxidation-Reduction; Thymine DNA Glycosylase	2013
5-hydroxymethylcytosine: a new insight into epigenetics in cancer. Cancer biology & therapy, 2014, Volume: 15, Issue:1 Topics: 5-Methylcytosine; Animals; Brain Neoplasms; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Humans; Leukemia; Mixed Function Oxygenases; Neoplasms; Proto-Oncogene Proteins	2014
5-hydroxymethylcytosine profiling as an indicator of cellular state. Epigenomics, 2013, Volume: 5, Issue:6 Topics: 5-Methylcytosine; Animals; Biomarkers, Tumor; Cytosine; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Models, Genetic; Neoplasms; Organ Specificity; Signal Transduction	2013
The role of TET family proteins and 5-hydroxymethylcytosine in human tumors. Histology and histopathology, 2014, Volume: 29, Issue:8 Topics: 5-Methylcytosine; Cell Transformation, Neoplastic; Cytosine; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Humans; Neoplasms	2014
The role of 5-hydroxymethylcytosine in human cancer. Cell and tissue research, 2014, Volume: 356, Issue:3 Topics: 5-Methylcytosine; Cytosine; DNA Methylation; DNA, Neoplasm; Humans; Neoplasms; Oxidation-Reduction	2014
Playing TETris with DNA modifications. The EMBO journal, 2014, Jun-02, Volume: 33, Issue:11 Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Gene Expression Regulation; Humans; Neoplasms; Neurodegenerative Diseases; Oxidation-Reduction; Signal Transduction	2014
Mechanism and function of oxidative reversal of DNA and RNA methylation. Annual review of biochemistry, 2014, Volume: 83 Topics: 5-Methylcytosine; Animals; Cytosine; DNA; DNA Methylation; Escherichia coli; Gene Expression Regulation; Genome; Germ Cells; HEK293 Cells; Humans; Methylation; Mice; Neoplasms; Oxygen; RNA; Stem Cells; Transcriptome	2014
Connections between TET proteins and aberrant DNA modification in cancer. Trends in genetics : TIG, 2014, Volume: 30, Issue:10 Topics: 5-Methylcytosine; Azacitidine; Cytosine; Decitabine; Dioxygenases; DNA Methylation; DNA Modification Methylases; DNA-Binding Proteins; Hematologic Neoplasms; Humans; Isocitrate Dehydrogenase; Mixed Function Oxygenases; Molecular Targeted Therapy; Mutation; Neoplasms; Proto-Oncogene Proteins; Small Molecule Libraries	2014
Loss of 5-hydroxymethylcytosine in cancer: cause or consequence? Genomics, 2014, Volume: 104, Issue:5 Topics: 5-Methylcytosine; Animals; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; DNA, Neoplasm; Humans; Mixed Function Oxygenases; Neoplasms; Oxidation-Reduction; Proto-Oncogene Proteins	2014
5-hydroxymethylcytosine: a potential therapeutic target in cancer. Epigenomics, 2014, Volume: 6, Issue:5 Topics: 5-Methylcytosine; Animals; Antineoplastic Agents; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Epigenesis, Genetic; Humans; Neoplasms	2014
5-Hydroxymethylcytosine: An epigenetic mark frequently deregulated in cancer. Biochimica et biophysica acta, 2015, Volume: 1855, Issue:2 Topics: 5-Methylcytosine; Biomarkers, Tumor; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Humans; Isocitrate Dehydrogenase; Mutation; Neoplasms; Proto-Oncogene Proteins	2015
Hydroxymethylation and its potential implication in DNA repair system: A review and future perspectives. Gene, 2015, Jun-15, Volume: 564, Issue:2 Topics: 5-Methylcytosine; Animals; Cytosine; DNA Repair; Humans; Mental Disorders; Neoplasms; Neurodegenerative Diseases	2015
5-hydroxymethylcytosine in cancer: significance in diagnosis and therapy. Cancer genetics, 2015, Volume: 208, Issue:5 Topics: 5-Methylcytosine; Cytosine; Dioxygenases; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; Humans; Isocitrate Dehydrogenase; Neoplasms; Proto-Oncogene Proteins	2015
[TET proteins and epigenetic modifications in cancers]. Postepy higieny i medycyny doswiadczalnej (Online), 2015, Dec-16, Volume: 69 Topics: 5-Methylcytosine; Dioxygenases; DNA-Binding Proteins; Epigenesis, Genetic; Genetic Predisposition to Disease; Histones; Humans; Mixed Function Oxygenases; Mutation; Neoplasms; Protein Processing, Post-Translational; Proto-Oncogene Proteins	2015
Portraits of TET-mediated DNA hydroxymethylation in cancer. Current opinion in genetics & development, 2016, Volume: 36 Topics: 5-Methylcytosine; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Gene Expression Regulation; Humans; Mixed Function Oxygenases; Neoplasms; Promoter Regions, Genetic; Proto-Oncogene Proteins	2016
Physiological and pathological implications of 5-hydroxymethylcytosine in diseases. Oncotarget, 2016, 07-26, Volume: 7, Issue:30 Topics: 5-Methylcytosine; CpG Islands; Dioxygenases; DNA (Cytosine-5-)-Methyltransferases; DNA Demethylation; DNA Methylation; DNA-Binding Proteins; Embryonic Development; Enzyme Inhibitors; Epigenesis, Genetic; Humans; Mixed Function Oxygenases; Neoplasms; Nervous System Diseases; Promoter Regions, Genetic; Proto-Oncogene Proteins	2016
The emerging insights into catalytic or non-catalytic roles of TET proteins in tumors and neural development. Oncotarget, 2016, Sep-27, Volume: 7, Issue:39 Topics: 5-Methylcytosine; Animals; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Neoplasm Proteins; Neoplasms; Nerve Tissue Proteins; Neurogenesis; Neurons; Protein Conformation; Signal Transduction; Structure-Activity Relationship	2016
Decreased 5-hydroxymethylcytosine levels correlate with cancer progression and poor survival: a systematic review and meta-analysis. Oncotarget, 2017, Jan-03, Volume: 8, Issue:1 Topics: 5-Methylcytosine; Cytosine; DNA Methylation; Humans; Lymphatic Metastasis; Neoplasms; Prognosis	2017
The application of genome-wide 5-hydroxymethylcytosine studies in cancer research. Epigenomics, 2017, Volume: 9, Issue:1 Topics: 5-Methylcytosine; Animals; Biomarkers, Tumor; DNA Methylation; Epigenesis, Genetic; Humans; Neoplasms; Sequence Analysis, DNA	2017
5-Hydroxymethylcytosine, the sixth base of the genome. Angewandte Chemie (International ed. in English), 2011, Jul-11, Volume: 50, Issue:29 Topics: 5-Methylcytosine; Animals; Bacteriophages; Cell Differentiation; Central Nervous System; Chromatography, Liquid; Cytosine; DNA; DNA Methylation; DNA, Viral; Epigenesis, Genetic; Female; Genome; Humans; Male; Mass Spectrometry; Neoplasms; Pluripotent Stem Cells	2011
[Cytosine methylation in DNA and its role in cancer therapy]. Postepy biochemii, 2011, Volume: 57, Issue:1 Topics: 5-Methylcytosine; Animals; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Gene Expression Regulation, Neoplastic; Humans; Neoplasms	2011
DNA methylation testing and marker validation using PCR: diagnostic applications. Expert review of molecular diagnostics, 2012, Volume: 12, Issue:1 Topics: 5-Methylcytosine; Biomarkers; Cell Differentiation; CpG Islands; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Germ Cells; Humans; Molecular Diagnostic Techniques; Neoplasms; Polymerase Chain Reaction	2012
Tet family proteins and 5-hydroxymethylcytosine in development and disease. Development (Cambridge, England), 2012, Volume: 139, Issue:11 Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; DNA-Binding Proteins; Embryonic Development; Epigenesis, Genetic; Humans; Mice; Mice, Knockout; Molecular Structure; Multigene Family; Neoplasms; Oxidation-Reduction; Protein Structure, Tertiary; Proto-Oncogene Proteins	2012
[Oxidation and deamination of nucleobases as an epigenetic tool]. Postepy higieny i medycyny doswiadczalnej (Online), 2012, May-24, Volume: 66 Topics: 5-Methylcytosine; Animals; Base Composition; Chromatin Assembly and Disassembly; Cytosine; Deamination; DNA; DNA Methylation; DNA-Binding Proteins; Epigenomics; Gene Expression Regulation; Guanine; Mutation; Neoplasms; Oxidation-Reduction; Sequence Analysis, DNA; Transcription, Genetic	2012
Cancer genetics and epigenetics: two sides of the same coin? Cancer cell, 2012, Jul-10, Volume: 22, Issue:1 Topics: 5-Methylcytosine; DNA Methylation; DNA Repair; Epigenesis, Genetic; Humans; MicroRNAs; Neoplasms; Point Mutation; Signal Transduction	2012
Ten eleven translocation enzymes and 5-hydroxymethylation in mammalian development and cancer. Advances in experimental medicine and biology, 2013, Volume: 754 Topics: 5-Methylcytosine; Animals; Cell Differentiation; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Embryonic Development; Humans; Neoplasms; Proto-Oncogene Proteins	2013
Cytosine methylation and DNA repair. Current topics in microbiology and immunology, 2006, Volume: 301 Topics: 5-Methylcytosine; Animals; Bacteria; CpG Islands; Cytosine; Dealkylation; Deamination; DNA Glycosylases; DNA Methylation; DNA Repair; DNA Replication; Humans; Mutagens; Neoplasms	2006
5-methylcytosine, gene regulation, and cancer. Advances in cancer research, 1983, Volume: 40 Topics: 5-Methylcytosine; Animals; Azacitidine; Base Sequence; Carcinogens; Cell Transformation, Neoplastic; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Replication; Fibroblasts; Gene Expression Regulation; Humans; Models, Biological; Muscles; Neoplasms; Oncogenes	1983
5-Methylcytosine depletion during tumour development: an extension of the miscoding concept. British journal of cancer, 1983, Volume: 48, Issue:4 Topics: 5-Methylcytosine; Alkylation; Amino Acid Metabolism, Inborn Errors; Animals; Carcinogens; Cell Transformation, Neoplastic; Choline Deficiency; Cytosine; DNA; DNA Repair; Gene Expression Regulation; Humans; Methylation; Methyltransferases; Models, Genetic; Neoplasms; Oncogenes; Rats; Tyrosine; Vitamin B 6 Deficiency	1983
DNA methylation and mutation. Mutation research, 1993, Volume: 285, Issue:1 Topics: 5-Methylcytosine; Animals; Base Composition; Cytosine; Dinucleoside Phosphates; DNA; DNA Repair; Humans; Methylation; Mutation; Neoplasms	1993
Spontaneous mutations and fidelogens. Basic life sciences, 1993, Volume: 61 Topics: 5-Methylcytosine; Animals; Antimutagenic Agents; Apurinic Acid; Cytosine; DNA Repair; DNA Replication; Escherichia coli; Free Radicals; Humans; Mutation; Neoplasms; Recombination, Genetic; Saccharomyces cerevisiae	1993
DNA methylation and cancer. EXS, 1993, Volume: 64 Topics: 5-Methylcytosine; Animals; Cytosine; Dinucleoside Phosphates; DNA; DNA Repair; Genes, p53; Genes, Tumor Suppressor; Humans; Methylation; Mutagens; Mutation; Neoplasms; Transcription, Genetic	1993
The 1995 Walter Hubert Lecture--molecular epidemiology of human cancer: insights from the mutational analysis of the p53 tumour-suppressor gene. British journal of cancer, 1996, Volume: 73, Issue:3 Topics: 5-Methylcytosine; Cytosine; DNA, Neoplasm; Genes, p53; Humans; Mutation; Neoplasms; Tumor Suppressor Protein p53	1996
DNA methylation and polyamines in embryonic development and cancer. The International journal of developmental biology, 1995, Volume: 39, Issue:5 Topics: 5-Methylcytosine; Animals; Cell Transformation, Neoplastic; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Replication; Embryonic and Fetal Development; Female; Gene Expression Regulation, Developmental; Humans; Male; Methylation; Mice; Mutagenesis; Neoplasms; Nucleic Acid Conformation; Oogenesis; Polyamines; Replication Origin; Spermatogenesis; Transcription, Genetic	1995
DNA methylation errors and cancer. Cancer research, 1996, Jun-01, Volume: 56, Issue:11 Topics: 5-Methylcytosine; Animals; Cytosine; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Humans; Imprinting, Psychological; Methylation; Mutation; Neoplasms	1996
Mechanisms of spontaneous human cancers. Environmental health perspectives, 1996, Volume: 104 Suppl 3 Topics: 5-Methylcytosine; CpG Islands; Cytosine; Disease Susceptibility; DNA Damage; Environmental Exposure; Humans; Mutation; Neoplasms; Oxidation-Reduction; Risk Factors; Smoking	1996
The relationship of DNA methylation to cancer. Cancer surveys, 1996, Volume: 28 Topics: 5-Methylcytosine; Azacitidine; CpG Islands; Cytosine; Decitabine; DNA Methylation; Enzyme Inhibitors; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Methyltransferases; Neoplasms	1996
Mutagenic and epigenetic effects of DNA methylation. Mutation research, 1997, Volume: 386, Issue:2 Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; Enzymes; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Humans; Mutation; Neoplasms; Transcription, Genetic; Uracil	1997
Altered DNA methylation and genome instability: a new pathway to cancer? Proceedings of the National Academy of Sciences of the United States of America, 1997, Mar-18, Volume: 94, Issue:6 Topics: 5-Methylcytosine; Animals; Cytosine; DNA Methylation; DNA, Neoplasm; Genes, Tumor Suppressor; Humans; Mice; Neoplasms; Promoter Regions, Genetic	1997
DNA methylation and the association between genetic and epigenetic changes: relation to carcinogenesis. Mutation research, 1997, Apr-14, Volume: 375, Issue:1 Topics: 5-Methylcytosine; Alkylating Agents; Animals; Cytosine; DNA Damage; DNA Methylation; DNA Modification Methylases; DNA Repair; Enzyme Inhibitors; Humans; Mutation; Neoplasms; Nucleic Acid Synthesis Inhibitors; Oxidative Stress; Topoisomerase II Inhibitors	1997
Genetic and epigenetic aspects of DNA methylation on genome expression, evolution, mutation and carcinogenesis. Carcinogenesis, 1997, Volume: 18, Issue:5 Topics: 5-Methylcytosine; Alleles; Animals; Cell Differentiation; Chromatin; CpG Islands; Cytosine; DNA Methylation; DNA, Neoplasm; Gene Expression Regulation; Gene Expression Regulation, Developmental; Humans; Mutation; Neoplasms; S-Adenosylmethionine	1997
Oncogenic mechanisms mediated by DNA methylation. Molecular medicine today, 1997, Volume: 3, Issue:5 Topics: 5-Methylcytosine; Animals; Cytosine; DNA; DNA Methylation; Humans; Mammals; Mutation; Neoplasms; Nucleic Acid Conformation; Oncogenes	1997
Mutagenesis in the P53 gene. Biochimica et biophysica acta, 1997, Aug-08, Volume: 1333, Issue:1 Topics: 5-Methylcytosine; Carcinogens, Environmental; Cytosine; DNA Damage; Genes, p53; Humans; Mutagens; Mutation; Neoplasms	1997
Dynamic interrelationships between DNA replication, methylation, and repair. American journal of human genetics, 1997, Volume: 61, Issue:6 Topics: 5-Methylcytosine; Animals; Chromatin; CpG Islands; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA Repair; DNA Replication; DNA, Neoplasm; Gene Expression Regulation; Humans; Models, Genetic; Mutation; Neoplasm Proteins; Neoplasms; Proliferating Cell Nuclear Antigen; Tumor Suppressor Protein p53	1997
Formation and repair of DNA lesions in the p53 gene: relation to cancer mutations? Environmental and molecular mutagenesis, 1998, Volume: 31, Issue:3 Topics: 5-Methylcytosine; Animals; Benzo(a)pyrene; Breast Neoplasms; Carcinogens, Environmental; Colonic Neoplasms; Cytosine; Deamination; DNA Adducts; DNA Damage; DNA Mutational Analysis; DNA Repair; Genes, p53; Humans; Lung Neoplasms; Mice; Mutagenesis; Neoplasms; Neoplasms, Radiation-Induced; Selection, Genetic; Skin Neoplasms; Smoking; Tumor Suppressor Protein p53; Ultraviolet Rays	1998
DNA methylation: past, present and future directions. Carcinogenesis, 2000, Volume: 21, Issue:3 Topics: 5-Methylcytosine; Antimetabolites, Antineoplastic; Azacitidine; Carcinogens; Chromatin; Cytosine; DNA Methylation; DNA Repair; Forecasting; Gene Expression; Humans; Neoplasms	2000
Changes in DNA methylation in neoplasia: pathophysiology and therapeutic implications. Annals of internal medicine, 2001, Apr-03, Volume: 134, Issue:7 Topics: 5-Methylcytosine; Acetylation; Antineoplastic Agents; Clinical Trials, Phase I as Topic; Clinical Trials, Phase II as Topic; CpG Islands; Cytosine; DNA Methylation; Fetal Hemoglobin; Gene Expression Regulation, Neoplastic; Hematologic Diseases; Histones; Humans; Methylation; Neoplasms	2001
Methylation matters. Journal of medical genetics, 2001, Volume: 38, Issue:5 Topics: 5-Methylcytosine; Chromosome Aberrations; CpG Islands; Cytosine; DNA Methylation; DNA Transposable Elements; Gene Expression Regulation, Neoplastic; Genomics; Humans; Neoplasms; Oncogenes; Syndrome	2001
Methylation, mutation and cancer. BioEssays : news and reviews in molecular, cellular and developmental biology, 1992, Volume: 14, Issue:1 Topics: 5-Methylcytosine; Animals; Cell Transformation, Neoplastic; Cytosine; Deamination; DNA; DNA, Neoplasm; Female; Genes, p53; Genetic Diseases, Inborn; Humans; Male; Methylation; Mutation; Neoplasms; Neoplasms, Experimental; Vertebrates	1992
5-Methylcytosine as an endogenous mutagen in the p53 tumor suppressor gene. Princess Takamatsu symposia, 1991, Volume: 22 Topics: 5-Methylcytosine; Animals; Cytosine; DNA; Genes, p53; Humans; Mutagens; Mutation; Neoplasms	1991
Hypomethylation of DNA in the regulation of gene expression. Developmental biology (New York, N.Y. : 1985), 1988, Volume: 5 Topics: 5-Methylcytosine; Animals; Azacitidine; Cell Differentiation; Cytosine; DNA; Gene Expression Regulation; Humans; Methylation; Methyltransferases; Neoplasms	1988

Other Studies

52 other study(ies) available for 5-methylcytosine and Benign Neoplasms

Article	Year
Cell-free DNA 5-hydroxymethylcytosine profiles of long non-coding RNA genes enable early detection and progression monitoring of human cancers. Clinical epigenetics, 2021, 10-24, Volume: 13, Issue:1 Topics: 5-Methylcytosine; Cell-Free Nucleic Acids; Disease Progression; Early Detection of Cancer; Humans; Neoplasms; RNA, Long Noncoding	2021
BiLSTM-5mC: A Bidirectional Long Short-Term Memory-Based Approach for Predicting 5-Methylcytosine Sites in Genome-Wide DNA Promoters. Molecules (Basel, Switzerland), 2021, Dec-07, Volume: 26, Issue:24 Topics: 5-Methylcytosine; Aging; Deep Learning; DNA; DNA Methylation; Humans; Memory, Short-Term; Neoplasms; Promoter Regions, Genetic	2021
5-Hydroxymethylcytosine (5hmC) at or near cancer mutation hot spots as potential targets for early cancer detection. BMC research notes, 2022, Apr-21, Volume: 15, Issue:1 Topics: 5-Methylcytosine; DNA; DNA Methylation; Humans; Mutation; Neoplasms	2022
Hydroxymethylation-Specific Ligation-Mediated Single Quantum Dot-Based Nanosensors for Sensitive Detection of 5-Hydroxymethylcytosine in Cancer Cells. Analytical chemistry, 2022, 07-12, Volume: 94, Issue:27 Topics: 5-Methylcytosine; Animals; Biotin; DNA; DNA Methylation; Mammals; Neoplasms; Quantum Dots	2022
Detection of rare mutations, copy number alterations, and methylation in the same template DNA molecules. Proceedings of the National Academy of Sciences of the United States of America, 2023, 04-11, Volume: 120, Issue:15 Topics: 5-Methylcytosine; DNA; DNA Copy Number Variations; DNA Methylation; Female; Humans; Methylation; Mutation; Neoplasms	2023
Development of Novel Epigenetic Anti-Cancer Therapy Targeting TET Proteins. International journal of molecular sciences, 2023, Nov-15, Volume: 24, Issue:22 Topics: 5-Methylcytosine; Animals; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Fibroblasts; Leukemia; Mice; Mitoxantrone; Neoplasms	2023
In silico structural analysis of sequences containing 5-hydroxymethylcytosine reveals its potential as binding regulator for development, ageing and cancer-related transcription factors. Epigenetics, 2021, Volume: 16, Issue:5 Topics: 5-Methylcytosine; Aging; DNA Methylation; G-Quadruplexes; Humans; Neoplasms; Transcription Factors	2021
Pan-cancer analysis of m World journal of surgical oncology, 2021, Jul-29, Volume: 19, Issue:1 Topics: 5-Methylcytosine; DNA Copy Number Variations; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Genes, Regulator; Humans; Mutation; Neoplasms; Prognosis	2021
The interaction between cytosine methylation and processes of DNA replication and repair shape the mutational landscape of cancer genomes. Nucleic acids research, 2017, Jul-27, Volume: 45, Issue:13 Topics: 5-Methylcytosine; Colorectal Neoplasms; CpG Islands; DNA Methylation; DNA Mismatch Repair; DNA Polymerase II; DNA Repair; DNA Replication; Genes, APC; Genes, Neoplasm; Genes, p53; Genome, Human; Humans; Microsatellite Instability; Mutation; Neoplasms; Poly-ADP-Ribose Binding Proteins	2017
5-Hydroxymethylcytosine signatures in cell-free DNA provide information about tumor types and stages. Cell research, 2017, Volume: 27, Issue:10 Topics: 5-Methylcytosine; Adult; Aged; Animals; Cell-Free Nucleic Acids; Circulating Tumor DNA; Cytosine; DNA Methylation; Epigenesis, Genetic; Female; Humans; Male; Middle Aged; Neoplasm Staging; Neoplasms	2017
5-Hydroxymethylcytosine signatures in circulating cell-free DNA as diagnostic biomarkers for human cancers. Cell research, 2017, Volume: 27, Issue:10 Topics: 5-Methylcytosine; Adolescent; Adult; Aged; Biomarkers, Tumor; Cell-Free Nucleic Acids; Circulating Tumor DNA; DNA Methylation; Epigenomics; Female; Gene Expression Regulation, Neoplastic; Humans; Liquid Biopsy; Male; Middle Aged; Neoplasms; Young Adult	2017
Integrating DNA Methylation and Hydroxymethylation Data with the Mint Pipeline. Cancer research, 2017, 11-01, Volume: 77, Issue:21 Topics: 5-Methylcytosine; Computational Biology; DNA Methylation; Epigenesis, Genetic; High-Throughput Nucleotide Sequencing; Humans; Immunoprecipitation; Neoplasms; Software	2017
DNA Replication and associated repair pathways are involved in the mutagenesis of methylated cytosine. DNA repair, 2018, Volume: 62 Topics: 5-Methylcytosine; Carcinogenesis; CpG Islands; DNA Mismatch Repair; DNA Polymerase II; DNA Replication; Humans; Mutagenesis; Neoplasms	2018
Allele-Specific DNA Methylation and Its Interplay with Repressive Histone Marks at Promoter-Mutant TERT Genes. Cell reports, 2017, 12-26, Volume: 21, Issue:13 Topics: 5-Methylcytosine; Alleles; Base Sequence; Cell Line, Tumor; CpG Islands; DNA; DNA Methylation; Enhancer of Zeste Homolog 2 Protein; Histone Code; Humans; Mutation; Neoplasms; Polycomb Repressive Complex 2; Promoter Regions, Genetic; Protein Binding; Survival Analysis; Telomerase; Transcription, Genetic	2017
TET2 controls chemoresistant slow-cycling cancer cell survival and tumor recurrence. The Journal of clinical investigation, 2018, 08-31, Volume: 128, Issue:9 Topics: 5-Methylcytosine; Animals; Biomarkers, Tumor; Cell Cycle; Cell Line, Tumor; Cell Survival; Dioxygenases; DNA-Binding Proteins; Drug Resistance, Neoplasm; Epigenesis, Genetic; Female; Gene Knockdown Techniques; Humans; Mice; Mice, Inbred NOD; Mice, Nude; Mice, SCID; Neoplasms; Proto-Oncogene Proteins; Recurrence; Xenograft Model Antitumor Assays	2018
Glucose-regulated phosphorylation of TET2 by AMPK reveals a pathway linking diabetes to cancer. Nature, 2018, Volume: 559, Issue:7715 Topics: 5-Methylcytosine; Adenylate Kinase; Animals; Diabetes Mellitus; Dioxygenases; DNA; DNA Methylation; DNA-Binding Proteins; Enzyme Stability; Epigenesis, Genetic; Glucose; Glycated Hemoglobin; Humans; Hyperglycemia; Metformin; Mice; Mice, Nude; Neoplasms; Phosphorylation; Phosphoserine; Proto-Oncogene Proteins; Substrate Specificity; Xenograft Model Antitumor Assays	2018
Gene body profiles of 5-hydroxymethylcytosine: potential origin, function and use as a cancer biomarker. Epigenomics, 2018, Volume: 10, Issue:8 Topics: 5-Methylcytosine; Biomarkers, Tumor; Genome; Humans; Neoplasms	2018
Epigenetic control by sugar. Nature reviews. Cancer, 2018, Volume: 18, Issue:10 Topics: 5-Methylcytosine; Diabetes Mellitus; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Glucose; Humans; Neoplasms; Proto-Oncogene Proteins	2018
Sensitive detection of hydroxymethylcytosine levels in normal and neoplastic cells and tissues. Electrophoresis, 2019, Volume: 40, Issue:9 Topics: 5-Methylcytosine; Animals; Cell Dedifferentiation; DNA Methylation; Electrophoresis, Capillary; Fluorescence; Glioma; Humans; Lung Neoplasms; Mice; Neoplasms	2019
DNA Hypermethylation Encroachment at CpG Island Borders in Cancer Is Predisposed by H3K4 Monomethylation Patterns. Cancer cell, 2019, 02-11, Volume: 35, Issue:2 Topics: 5-Methylcytosine; Animals; Cell Line, Tumor; CpG Islands; DNA Methylation; DNA-Binding Proteins; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Histone-Lysine N-Methyltransferase; Histones; Humans; Male; Methylation; Mice, Inbred C57BL; Mice, Knockout; Myeloid-Lymphoid Leukemia Protein; Neoplasm Proteins; Neoplasms; Promoter Regions, Genetic	2019
Statistical methods for classification of 5hmC levels based on the Illumina Inifinium HumanMethylation450 (450k) array data, under the paired bisulfite (BS) and oxidative bisulfite (oxBS) treatment. PloS one, 2019, Volume: 14, Issue:6 Topics: 5-Methylcytosine; Case-Control Studies; DNA Methylation; Humans; Neoplasms; Oxidation-Reduction; Sulfites	2019
5-Hydroxymethylcytosine as a clinical biomarker: Fluorescence-based assay for high-throughput epigenetic quantification in human tissues. International journal of cancer, 2020, 01-01, Volume: 146, Issue:1 Topics: 5-Methylcytosine; Animals; Biomarkers, Tumor; Cost-Benefit Analysis; Epigenesis, Genetic; Fluorescence; High-Throughput Screening Assays; Humans; Mice; Neoplasms; Proof of Concept Study	2020
Tight correlation of 5-hydroxymethylcytosine and Polycomb marks in health and disease. Cell cycle (Georgetown, Tex.), 2013, Jun-15, Volume: 12, Issue:12 Topics: 5-Methylcytosine; Cell Differentiation; Cell Line, Tumor; Cytosine; DNA Methylation; Epigenomics; Female; Histones; Humans; In Vitro Techniques; Male; Neoplasms; Polycomb-Group Proteins	2013
The degree of global DNA hypomethylation in peripheral blood correlates with that in matched tumor tissues in several neoplasia. PloS one, 2014, Volume: 9, Issue:3 Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Brain Neoplasms; DNA Methylation; Epigenesis, Genetic; Female; Humans; Male; Middle Aged; Neoplasms; Young Adult	2014
Folic acid functionalized surface highlights 5-methylcytosine-genomic content within circulating tumor cells. Small (Weinheim an der Bergstrasse, Germany), 2014, Nov-12, Volume: 10, Issue:21 Topics: 5-Methylcytosine; Biomarkers, Tumor; Blood Chemical Analysis; Cells, Cultured; DNA Methylation; Enzyme-Linked Immunosorbent Assay; Folic Acid; Genes, Neoplasm; Humans; Microscopy, Confocal; Neoplasms; Neoplastic Cells, Circulating; Surface Properties; Survival Analysis	2014
Long noncoding RNA TARID directs demethylation and activation of the tumor suppressor TCF21 via GADD45A. Molecular cell, 2014, Aug-21, Volume: 55, Issue:4 Topics: 5-Methylcytosine; Basic Helix-Loop-Helix Transcription Factors; Cell Cycle Proteins; Cell Line, Tumor; CpG Islands; Cytosine; DNA Methylation; DNA Repair; Gene Expression Regulation, Neoplastic; Genome, Human; HEK293 Cells; Humans; Molecular Sequence Data; Neoplasms; Nuclear Proteins; Promoter Regions, Genetic; RNA, Long Noncoding; Thymine DNA Glycosylase	2014
Decrease of 5-hydroxymethylcytosine in rat liver with subchronic exposure to genotoxic carcinogens riddelliine and aristolochic acid. Molecular carcinogenesis, 2015, Volume: 54, Issue:11 Topics: 5-Methylcytosine; Animals; Aristolochic Acids; Carcinogenesis; Carcinogens; Cytosine; DNA-Binding Proteins; Epigenesis, Genetic; Liver; Mutation; Neoplasms; Pyrrolizidine Alkaloids; Rats; Rats, Inbred F344; Rats, Transgenic	2015
Quantification of 5-methylcytosine, 5-hydroxymethylcytosine and 5-carboxylcytosine from the blood of cancer patients by an enzyme-based immunoassay. Analytica chimica acta, 2014, Dec-10, Volume: 852 Topics: 5-Methylcytosine; Cytosine; DNA; Epigenesis, Genetic; Humans; Immunoenzyme Techniques; Limit of Detection; Neoplasms	2014
TET1 regulates hypoxia-induced epithelial-mesenchymal transition by acting as a co-activator. Genome biology, 2014, Dec-03, Volume: 15, Issue:12 Topics: 5-Methylcytosine; Basic Helix-Loop-Helix Transcription Factors; Catalytic Domain; Cell Hypoxia; Cell Line, Tumor; DNA-Binding Proteins; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Intracellular Signaling Peptides and Proteins; Membrane Proteins; Mixed Function Oxygenases; Neoplasms; Promoter Regions, Genetic; Proto-Oncogene Proteins	2014
CDA directs metabolism of epigenetic nucleosides revealing a therapeutic window in cancer. Nature, 2015, Aug-06, Volume: 524, Issue:7563 Topics: 5-Methylcytosine; Animals; Cell Death; Cell Line, Tumor; Cytidine; Cytidine Deaminase; Cytosine; Deoxycytidine; DNA; DNA Damage; DNA-Directed DNA Polymerase; Epigenesis, Genetic; Gene Expression Regulation, Enzymologic; Gene Expression Regulation, Neoplastic; Humans; Mice; Neoplasms; Nucleotides; Oxidation-Reduction; Phosphotransferases; Substrate Specificity; Up-Regulation; Uridine	2015
Development-linked changes in DNA methylation and hydroxymethylation in humans: interview with Dr Melanie Ehrlich. Epigenomics, 2015, Volume: 7, Issue:5 Topics: 5-Methylcytosine; DNA Methylation; Epigenesis, Genetic; Epigenomics; History, 20th Century; History, 21st Century; Humans; Methylation; Neoplasms; Organ Specificity	2015
MECP2 Is a Frequently Amplified Oncogene with a Novel Epigenetic Mechanism That Mimics the Role of Activated RAS in Malignancy. Cancer discovery, 2016, Volume: 6, Issue:1 Topics: 5-Methylcytosine; Alternative Splicing; Animals; Cell Line, Tumor; Cytosine; Epigenesis, Genetic; Gene Amplification; Humans; Methyl-CpG-Binding Protein 2; Mice; Neoplasm Transplantation; Neoplasms; Protein Isoforms; ras Proteins; Signal Transduction	2016
The decreased N Biochemical and biophysical research communications, 2016, Nov-04, Volume: 480, Issue:1 Topics: 3T3-L1 Cells; 5-Methylcytosine; Adenine; Animals; Chromatography, High Pressure Liquid; DNA; Gene Expression Regulation, Neoplastic; Hep G2 Cells; Humans; Liver Neoplasms; Mice; Mice, Inbred C57BL; Neoplasms; Tandem Mass Spectrometry	2016
Whole-genome analysis of the methylome and hydroxymethylome in normal and malignant lung and liver. Genome research, 2016, Volume: 26, Issue:12 Topics: 5-Methylcytosine; CpG Islands; DNA; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation; Humans; Liver; Lung; Neoplasms; Organ Specificity; Promoter Regions, Genetic; Whole Genome Sequencing	2016
Loss of UHRF2 expression is associated with human neoplasia, promoter hypermethylation, decreased 5-hydroxymethylcytosine, and high proliferative activity. Oncotarget, 2016, Nov-15, Volume: 7, Issue:46 Topics: 5-Methylcytosine; Biomarkers, Tumor; Cell Line, Tumor; Cell Proliferation; DNA Methylation; Epigenesis, Genetic; Gene Expression Regulation, Neoplastic; Humans; Lymphocytes; Lymphoid Progenitor Cells; Neoplasm Grading; Neoplasms; Promoter Regions, Genetic; Protein Transport; Ubiquitin-Protein Ligases	2016
Acetylation Enhances TET2 Function in Protecting against Abnormal DNA Methylation during Oxidative Stress. Molecular cell, 2017, Jan-19, Volume: 65, Issue:2 Topics: 5-Methylcytosine; Acetylation; Chromatin; Dioxygenases; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; DNA-Binding Proteins; DNA, Neoplasm; E1A-Associated p300 Protein; HCT116 Cells; Histone Deacetylase 1; Histone Deacetylase 2; Humans; Neoplasms; Oxidative Stress; Protein Binding; Protein Processing, Post-Translational; Protein Stability; Proto-Oncogene Proteins; RNA Interference; Time Factors; Transfection; Ubiquitination	2017
5-Hydroxymethylcytosine is strongly depleted in human cancers but its levels do not correlate with IDH1 mutations. Cancer research, 2011, Dec-15, Volume: 71, Issue:24 Topics: 5-Methylcytosine; Animals; Base Sequence; Brain; Brain Neoplasms; Carcinoma, Squamous Cell; Cell Line, Tumor; Chromatography, Liquid; Cytosine; DNA-Binding Proteins; DNA, Neoplasm; Female; Gene Expression Regulation, Neoplastic; HEK293 Cells; Humans; Immunohistochemistry; Isocitrate Dehydrogenase; Lung Neoplasms; Male; Mice; Mixed Function Oxygenases; Molecular Structure; Mutation; Neoplasms; Proto-Oncogene Proteins; Reverse Transcriptase Polymerase Chain Reaction	2011
Loss of 5-hydroxymethylcytosine is accompanied with malignant cellular transformation. Cancer science, 2012, Volume: 103, Issue:4 Topics: 5-Methylcytosine; Cell Line, Tumor; Cell Transformation, Neoplastic; Colorectal Neoplasms; Cytosine; DNA Methylation; DNA-Binding Proteins; Gene Knockdown Techniques; Humans; Mixed Function Oxygenases; Mutation; Neoplasms; Proto-Oncogene Proteins; Stomach Neoplasms	2012
Tumor development is associated with decrease of TET gene expression and 5-methylcytosine hydroxylation. Oncogene, 2013, Jan-31, Volume: 32, Issue:5 Topics: 5-Methylcytosine; Animals; Biomarkers, Tumor; Cell Transformation, Neoplastic; Cytosine; Dioxygenases; DNA-Binding Proteins; Down-Regulation; Humans; Hydroxylation; Mice; Mixed Function Oxygenases; Neoplasms; Proto-Oncogene Proteins	2013
Germ-line variants in methyl-group metabolism genes and susceptibility to DNA methylation in normal tissues and human primary tumors. Cancer research, 2002, Aug-01, Volume: 62, Issue:15 Topics: 5-Methylcytosine; 5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase; Adenocarcinoma; Breast Neoplasms; Colorectal Neoplasms; CpG Islands; Cystathionine beta-Synthase; Cytosine; DNA Methylation; DNA, Neoplasm; Genetic Predisposition to Disease; Germ-Line Mutation; Humans; Lung Neoplasms; Methylenetetrahydrofolate Reductase (NADPH2); Neoplasms; Oxidoreductases Acting on CH-NH Group Donors	2002
Cellular vitamins, DNA methylation and cancer risk. The Journal of nutrition, 2002, Volume: 132, Issue:8 Suppl Topics: 5-Methylcytosine; Cytosine; DNA Methylation; Humans; Immunohistochemistry; Neoplasms; Risk Factors; Vitamins	2002
A systematic profile of DNA methylation in human cancer cell lines. Cancer research, 2003, Mar-01, Volume: 63, Issue:5 Topics: 5-Methylcytosine; Azacitidine; Cluster Analysis; CpG Islands; Cytosine; Decitabine; DNA Methylation; DNA, Neoplasm; Genes, Tumor Suppressor; Germ-Line Mutation; Humans; Neoplasms; Oligonucleotide Array Sequence Analysis; Tumor Cells, Cultured	2003
Methyl-CpG binding proteins identify novel sites of epigenetic inactivation in human cancer. The EMBO journal, 2003, Dec-01, Volume: 22, Issue:23 Topics: 5-Methylcytosine; Amino Acid Sequence; Breast Neoplasms; Chromatin; Chromosomal Proteins, Non-Histone; Chromosome Mapping; CpG Islands; DNA Methylation; DNA-Binding Proteins; Female; Humans; Methyl-CpG-Binding Protein 2; Microscopy, Confocal; Molecular Sequence Data; Neoplasms; Nucleic Acid Hybridization; Oligonucleotide Array Sequence Analysis; Peptide Fragments; Polymerase Chain Reaction; Promoter Regions, Genetic; Repressor Proteins; Tumor Cells, Cultured	2003
Determination of 5-methyl-cytosine and cytosine in tumor DNA of cancer patients. Electrophoresis, 2005, Volume: 26, Issue:6 Topics: 5-Methylcytosine; Cytosine; DNA Methylation; DNA, Neoplasm; Electrophoresis, Capillary; Humans; Neoplasms; Reproducibility of Results	2005
FBXW7/hCDC4 is a general tumor suppressor in human cancer. Cancer research, 2007, Oct-01, Volume: 67, Issue:19 Topics: 5-Methylcytosine; Amination; Cell Cycle Proteins; Dinucleotide Repeats; DNA Methylation; F-Box Proteins; F-Box-WD Repeat-Containing Protein 7; Gene Expression Regulation, Neoplastic; Gene Silencing; Genes, Tumor Suppressor; Humans; Models, Molecular; Mutation; Neoplasms; Protein Isoforms; Substrate Specificity; Ubiquitin-Protein Ligases	2007
The 5-methylcytosine content of DNA from human tumors. Nucleic acids research, 1983, Oct-11, Volume: 11, Issue:19 Topics: 5-Methylcytosine; Brain Chemistry; Cytosine; DNA; DNA Restriction Enzymes; DNA, Neoplasm; Female; Humans; Methylation; Neoplasms; Placenta; Pregnancy; Structure-Activity Relationship	1983
Extent of DNA methylation in human tumor cells. Journal of the National Cancer Institute, 1983, Volume: 71, Issue:4 Topics: 5-Methylcytosine; Base Composition; Cell Line; Chromatography, High Pressure Liquid; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; Gene Expression Regulation; Humans; Methylation; Methyltransferases; Neoplasms	1983
Variable 5-methylcytosine levels in human tumor cell lines and fresh pediatric tumor explants. Cancer research, 1983, Volume: 43, Issue:10 Topics: 5-Methylcytosine; Autoradiography; Cell Line; Cerebellar Neoplasms; Cytosine; DNA; Fibroblasts; Humans; Medulloblastoma; Neoplasms; Neuroblastoma; Retinoblastoma	1983
A cytosine methyltransferase converts 5-methylcytosine in DNA to thymine. Biochemistry, 1995, Nov-14, Volume: 34, Issue:45 Topics: 5-Methylcytosine; Cytosine; DNA; DNA-Cytosine Methylases; Escherichia coli; Humans; Methylation; Molecular Structure; Mutagenesis; Neoplasms; S-Adenosylhomocysteine; S-Adenosylmethionine; Thymine	1995
Methylation and p16: suppressing the suppressor. Nature medicine, 1995, Volume: 1, Issue:7 Topics: 5-Methylcytosine; Carrier Proteins; Cell Transformation, Neoplastic; Cocarcinogenesis; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Cytosine; DNA; Gene Expression Regulation; Genes, Tumor Suppressor; Genomic Imprinting; Humans; Methylation; Models, Genetic; Neoplasms	1995
5' CpG island methylation is associated with transcriptional silencing of the tumour suppressor p16/CDKN2/MTS1 in human cancers. Nature medicine, 1995, Volume: 1, Issue:7 Topics: 5-Methylcytosine; Alleles; Azacitidine; Base Sequence; Brain Neoplasms; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Carrier Proteins; Chromosomes, Human, Pair 9; CpG Islands; Cyclin-Dependent Kinase Inhibitor p16; Cytosine; Decitabine; DNA, Neoplasm; Gene Expression Regulation, Neoplastic; Genes, Tumor Suppressor; Glioma; Head and Neck Neoplasms; Humans; Lung Neoplasms; Methylation; Molecular Sequence Data; Neoplasm Proteins; Neoplasms; Sequence Deletion; Transcription, Genetic; Tumor Cells, Cultured	1995
Hypomethylation of DNA: a possible nongenotoxic mechanism underlying the role of cell proliferation in carcinogenesis. Environmental health perspectives, 1993, Volume: 101 Suppl 5 Topics: 5-Methylcytosine; Animals; Cell Division; Cytosine; DNA; Female; Liver Neoplasms, Experimental; Male; Methylation; Mice; Neoplasms; Proto-Oncogenes	1993