Page last updated: 2024-08-24

5-methylcytosine and Aging

5-methylcytosine has been researched along with Aging in 55 studies

Research

Studies (55)

Timeframe	Studies, this research(%)	All Research%
pre-1990	7 (12.73)	18.7374
1990's	3 (5.45)	18.2507
2000's	3 (5.45)	29.6817
2010's	35 (63.64)	24.3611
2020's	7 (12.73)	2.80

Authors

Authors	Studies
Cheng, X; Li, Q; Liu, T; Wang, J	1
Borkowska, J; Buyanovskaya, O; Charzewski, L; Domaszewska-Szostek, A; Kołodziej, P; Noszczyk, B; Połosak, J; Puzianowska-Kuznicka, M; Stańczyk, M; Wicik, Z	1
Andreou, AZ; Kouidou, S; Malousi, A	1
Farrell, C; Fehling, HL; Henkhaus, R; Morselli, M; Pellegrini, M; Rubbi, L	1
Costa, SFDS; de Menezes, VCB; de Souza, FTA; de Souza, RP; Gomes, CC; Gomez, RS; Siqueira, EC	1
Cisterna, B; Lacavalla, MA; Malatesta, M; Zancanaro, C	1
Lee, AWT; Lee, TL; Liao, J; Luk, ACS; Qi, H; Suen, HC; Yang, L	1
Fernández, AF; Fraga, MF; López, V	1
Lunnon, K; Smith, RG	1
Bacalini, MG; Breusing, N; Bürkle, A; Caiafa, P; Calabrese, R; Capri, M; Ciccarone, F; Franceschi, C; Grune, T; Guastafierro, T; Malavolta, M; Moreno-Villanueva, M; Reale, A; Valentini, E; Zampieri, M	1
Atlante, S; Azzimato, V; Baumgart, M; Braun, T; Cellerino, A; Cencioni, C; Farsetti, A; Gaetano, C; Guenther, S; Heid, J; Kuenne, C; Martelli, F; Milano, G; Pompilio, G; Ripa, R; Rossi, G; Scopece, A; Spallotta, F; Zeiher, AM	1
Croix, CMS; Czerwinska, J; Foksinski, M; Gackowski, D; Gregg, SQ; Niedernhofer, LJ; Olinski, R; Starczak, M; Szpila, A; Tudek, B; Tupalska, A; Yousefzadeh, MJ; Zarakowska, E	1
Bieri, G; Gontier, G; Iyer, M; Ramalho-Santos, M; Shea, JM; Villeda, SA; Wheatley, EG	1
Cavalcante, RG; Dolinoy, DC; Kochmanski, J; Marchlewicz, EH; Sartor, MA	1
Ecker, JR; Hajkova, P; Luo, C	1
Aston, KI; Cairns, BR; Carrell, DT; Jenkins, TG	1
De Jonge, CJ	1
Arias, C; Bermúdez-Rattoni, F; Cadena-del-Castillo, C; Carmona-Aldana, F; Recillas-Targa, F; Valdes-Quezada, C	1
Niederberger, C	1
Cai, C; Cheng, Y; Dave, R; Davis, TH; Irier, H; Jin, P; Lin, L; Street, RC; Yao, B	1
Li, X; Shu, Q; Sun, W; Zang, L	1
Guibourt, V; Kraus, TF; Kretzschmar, HA	1
Chan, WY; Chung, JP; Kong, GW; Lee, TL; Qian, Y; Tang, NL; Tu, J	1
Bachman, M; Balasubramanian, S; Burgess, HE; Iurlaro, M; Murrell, A; Reik, W; Uribe-Lewis, S; Yang, X	1
Iatrou, A; Kenis, G; Lardenoije, R; Meuwissen, KPV; Rutten, BPF; Schmitz, C; Steinbusch, HWM; Vaessen, TSJ; van den Hove, DLA; van Hagen, BTJ	1
Guibourt, V; Kilinc, S; Kraus, TF; Kretzschmar, HA; Steinmaurer, M; Stieglitz, M	1
Freeman, WM; Giles, CB; Hadad, N; Masser, DR; Richardson, A; Sonntag, WE; Stanford, DR; Wren, JD	1
Huang, L; Jin, P; Li, L; Li, X; Lin, L; Shen, H; Shu, L; Sun, W; Xie, P; Xu, Q; Xu, Z	1
Bayón, GF; Belmonte, T; Carella, A; Cubillo, I; Del Real, Á; Delgado-Calle, J; Fernández, AF; Fraga, MF; García, MG; García-Castro, J; Pérez-Campo, FM; Riancho, JA; Sierra, MI; Toraño, EG; Urdinguio, RG	1
De Jager, PL; Klein, HU	1
Bacalini, MG; Bernhardt, J; Breusing, N; Bürkle, A; Caiafa, P; Calabrese, R; Ciccarone, F; Dollé, ME; Franceschi, C; Gonos, ES; Grune, T; Guastafierro, T; Hervonen, A; Jansen, E; Koller, B; Malavolta, M; Moreno-Villanueva, M; Reale, A; Sikora, E; Sindlinger, T; Slagboom, PE; Toussaint, O; Valentini, E; Zampieri, M	1
Fasolino, M; Liu, S; Wang, Y; Zhou, Z	1
Chen, YF; Hsu, MT; Lin, IH	1
Mazin, AL	1
Guzman, AE; Mitton, KP	1
Abraham, CR; King, GD; Rosene, DL	1
Chang, Q; Cheng, X; Dai, Q; Gearing, M; Godley, LA; He, C; Irier, H; Jin, P; Levey, AI; Li, X; Li, Y; Song, CX; Szulwach, KE; Upadhyay, AK; Vasanthakumar, A; Wu, H	1
Flax, JD; Soloway, PD	1
Chouliaras, L; Rutten, BP; van den Hove, DL	1
Irier, HA; Jin, P	1
Chen, H; Dzitoyeva, S; Manev, H	2
Abdel-Wahab, O; Bhatt, PK; Brennan, CW; Busque, L; Figueroa, ME; Godley, LA; Gonen, M; Hamilou, Z; Hassimi, M; Heguy, A; Levine, RL; Li, J; Mason, CE; Melnick, A; Mollica, L; Patel, JP; Provost, S; Socci, N; Vasanthakumar, A; Viale, A	1
Barciszewska, AM; Barciszewska, MZ; Rattan, SI	1
Adams, RL; Burdon, RH	1
Kunnath, L; Locker, J	1
Holliday, R	1
Jones, PA; Wilson, VL	1
Counts, JL; Goodman, JI; Kaznowski, JM; McClain, RM	1
Genda, Y; Nagane, Y; Tohgi, H; Ukitsu, M; Utsugisawa, K; Yoshimura, M	2
Glickman, BW; Stuart, GR	1
Blake, TJ; Drinkwater, RD; Morley, AA; Turner, DR	1
Vaniushin, BF; Zhavoronkova, EN	1
Hammen, RF; Johnson, TE; Simpson, VJ	1

Reviews

9 review(s) available for 5-methylcytosine and Aging

Article	Year
The role of 5-hydroxymethylcytosine in development, aging and age-related diseases. Ageing research reviews, 2017, Volume: 37 Topics: 5-Methylcytosine; Aging; Animals; Cell Differentiation; Cytosine; DNA Methylation; Epigenesis, Genetic; Humans; Neoplasms; Oxidation-Reduction	2017
DNA Modifications and Alzheimer's Disease. Advances in experimental medicine and biology, 2017, Volume: 978 Topics: 5-Methylcytosine; Aging; Alzheimer Disease; Animals; Causality; Disease Models, Animal; DNA Methylation; DNA-Cytosine Methylases; Epigenesis, Genetic; Forecasting; Gene Expression Regulation; Genome-Wide Association Study; Humans; Mice; Mice, Transgenic; Nerve Tissue Proteins; Tissue Array Analysis	2017
Dynamic DNA methylation: In the right place at the right time. Science (New York, N.Y.), 2018, 09-28, Volume: 361, Issue:6409 Topics: 5-Methylcytosine; Aging; Animals; Disease; DNA Methylation; Gene Editing; Gene Expression Regulation, Developmental; Humans; Memory; Neoplasms; Single-Cell Analysis; Transcription Factors; Transcription, Genetic	2018
From development to diseases: the role of 5hmC in brain. Genomics, 2014, Volume: 104, Issue:5 Topics: 5-Methylcytosine; Aging; Animals; Cytosine; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Humans; Nervous System Diseases; Neurons	2014
Uncovering the Role of the Methylome in Dementia and Neurodegeneration. Trends in molecular medicine, 2016, Volume: 22, Issue:8 Topics: 5-Methylcytosine; Aging; Animals; Brain; Dementia; DNA Methylation; Epigenesis, Genetic; Epigenomics; Humans; Neurodegenerative Diseases	2016
Suicidal function of DNA methylation in age-related genome disintegration. Ageing research reviews, 2009, Volume: 8, Issue:4 Topics: 5-Methylcytosine; Aging; Apoptosis; DNA Damage; DNA Methylation; Gene Silencing; Humans; Mutation; Retroviridae	2009
Focus on molecules: 5-methylcytosine, a possible epigenetic link between ageing and ocular disease. Experimental eye research, 2012, Volume: 96, Issue:1 Topics: 5-Methylcytosine; Aging; Animals; DNA Methylation; Epigenesis, Genetic; Eye Diseases; Gene Expression; Humans	2012
Dynamics of DNA methylation in aging and Alzheimer's disease. DNA and cell biology, 2012, Volume: 31 Suppl 1 Topics: 5-Methylcytosine; Aging; Alzheimer Disease; Animals; Cytosine; DNA; DNA Methylation; Humans; Neurodegenerative Diseases	2012
DNA methylation in eukaryotes. CRC critical reviews in biochemistry, 1982, Volume: 13, Issue:4 Topics: 5-Methylcytosine; Aging; Animals; Azacitidine; Base Sequence; Chromatin; Cytosine; Deoxyribonuclease HpaII; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Restriction Enzymes; DNA-Cytosine Methylases; Gene Expression Regulation; Globins; Methylation; Nucleic Acid Conformation; Ovalbumin	1982

Other Studies

46 other study(ies) available for 5-methylcytosine and Aging

Article	Year
BiLSTM-5mC: A Bidirectional Long Short-Term Memory-Based Approach for Predicting 5-Methylcytosine Sites in Genome-Wide DNA Promoters. Molecules (Basel, Switzerland), 2021, Dec-07, Volume: 26, Issue:24 Topics: 5-Methylcytosine; Aging; Deep Learning; DNA; DNA Methylation; Humans; Memory, Short-Term; Neoplasms; Promoter Regions, Genetic	2021
Alterations in 5hmC level and genomic distribution in aging-related epigenetic drift in human adipose stem cells. Epigenomics, 2020, Volume: 12, Issue:5 Topics: 5-Methylcytosine; Adipose Tissue; Aging; Binding Sites; Cellular Senescence; Dioxygenases; DNA Methylation; Epigenesis, Genetic; Epigenomics; Gene Expression Regulation; Genetic Drift; Humans; Protein Binding; Stem Cells	2020
In silico structural analysis of sequences containing 5-hydroxymethylcytosine reveals its potential as binding regulator for development, ageing and cancer-related transcription factors. Epigenetics, 2021, Volume: 16, Issue:5 Topics: 5-Methylcytosine; Aging; DNA Methylation; G-Quadruplexes; Humans; Neoplasms; Transcription Factors	2021
Targeted bisulfite sequencing for biomarker discovery. Methods (San Diego, Calif.), 2021, Volume: 187 Topics: 5-Methylcytosine; Age Factors; Aging; Biomarkers; DNA Methylation; Epigenesis, Genetic; Epigenomics; High-Throughput Nucleotide Sequencing; Humans; Models, Genetic; Sequence Analysis, DNA; Sulfites	2021
Effects of aging on DNA hydroxymethylation and methylation in human dental follicles. Archives of oral biology, 2020, Volume: 118 Topics: 5-Methylcytosine; Adolescent; Adult; Aging; Dental Sac; DNA; DNA Methylation; Female; Humans; Male; Young Adult	2020
Ultrastructural immunocytochemistry shows impairment of RNA pathways in skeletal muscle nuclei of old mice: A link to sarcopenia? European journal of histochemistry : EJH, 2021, Mar-24, Volume: 65, Issue:2 Topics: 5-Methylcytosine; Actins; Aging; Animals; Cell Nucleolus; Immunohistochemistry; Male; Mice, Inbred BALB C; Muscle, Skeletal; Ribonuclease, Pancreatic; RNA, Messenger; RNA, Ribosomal; Sarcopenia	2021
Transcriptomic and epigenomic profiling of young and aged spermatogonial stem cells reveals molecular targets regulating differentiation. PLoS genetics, 2021, Volume: 17, Issue:7 Topics: 5-Methylcytosine; Adult Germline Stem Cells; Aging; Alternative Splicing; Animals; Cell Differentiation; Epigenome; Gene Expression Profiling; Gene Expression Regulation; Lysine; Male; Mice, Inbred C57BL; Mice, Transgenic; RNA, Long Noncoding; Testis	2021
DNA Hydroxymethylation Levels Are Altered in Blood Cells From Down Syndrome Persons Enrolled in the MARK-AGE Project. The journals of gerontology. Series A, Biological sciences and medical sciences, 2018, 05-09, Volume: 73, Issue:6 Topics: 5-Methylcytosine; Adult; Aged; Aging; Cross-Sectional Studies; DNA Methylation; Down Syndrome; Epigenesis, Genetic; Europe; Female; Humans; Immunoblotting; Italy; Leukocytes, Mononuclear; Male; Middle Aged; Mixed Function Oxygenases; Proto-Oncogene Proteins; RNA, Messenger	2018
Age-dependent increase of oxidative stress regulates microRNA-29 family preserving cardiac health. Scientific reports, 2017, 12-04, Volume: 7, Issue:1 Topics: 5-Methylcytosine; Aging; Animals; Antagomirs; Cell Hypoxia; Cell Line; Collagen; DNA Methylation; Echocardiography; Fibroblasts; Fishes; Heart; Humans; MicroRNAs; Myocardium; Oxidative Stress; Up-Regulation; Zebrafish	2017
Oxidation Products of 5-Methylcytosine are Decreased in Senescent Cells and Tissues of Progeroid Mice. The journals of gerontology. Series A, Biological sciences and medical sciences, 2018, 07-09, Volume: 73, Issue:8 Topics: 5-Methylcytosine; Aging; Animals; Biomarkers; Cellular Senescence; DNA-Binding Proteins; Endonucleases; Epigenesis, Genetic; Fibroblasts; Fluorescent Antibody Technique; Mice; Mice, Inbred C57BL; Oxidation-Reduction; Polymerase Chain Reaction	2018
Tet2 Rescues Age-Related Regenerative Decline and Enhances Cognitive Function in the Adult Mouse Brain. Cell reports, 2018, 02-20, Volume: 22, Issue:8 Topics: 5-Methylcytosine; Aging; Animals; Brain; Cognition; Dentate Gyrus; Dioxygenases; DNA-Binding Proteins; Male; Mice, Inbred C57BL; Models, Animal; Nerve Regeneration; Neural Stem Cells; Neurogenesis; Parabiosis; Proto-Oncogene Proteins	2018
Age-related epigenome-wide DNA methylation and hydroxymethylation in longitudinal mouse blood. Epigenetics, 2018, Volume: 13, Issue:7 Topics: 5-Methylcytosine; Aging; Animals; DNA Methylation; Epigenesis, Genetic; Epigenomics; Female; Gene Expression Regulation; Genome; Male; Mice	2018
Paternal aging and associated intraindividual alterations of global sperm 5-methylcytosine and 5-hydroxymethylcytosine levels. Fertility and sterility, 2013, Volume: 100, Issue:4 Topics: 5-Methylcytosine; Adult; Age Factors; Aging; Cytosine; DNA; DNA Methylation; Enzyme-Linked Immunosorbent Assay; Humans; Male; Middle Aged; Paternal Age; Prospective Studies; Risk Factors; Spermatozoa; Up-Regulation	2013
Paternal age and sperm methylation status. Fertility and sterility, 2013, Volume: 100, Issue:4 Topics: 5-Methylcytosine; Aging; Cytosine; DNA; DNA Methylation; Humans; Male; Paternal Age; Spermatozoa	2013
Age-dependent increment of hydroxymethylation in the brain cortex in the triple-transgenic mouse model of Alzheimer's disease. Journal of Alzheimer's disease : JAD, 2014, Volume: 41, Issue:3 Topics: 5-Methylcytosine; Age Factors; Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cerebral Cortex; Cytosine; Disease Models, Animal; Gene Expression Regulation; Genotype; Humans; Methylation; Mice; Mice, Inbred C57BL; Mice, Transgenic; Mutation; Presenilin-1; tau Proteins	2014
Re: paternal aging and associated intraindividual alterations of global sperm 5-methylcytosine and 5-hydroxymethylcytosine levels. The Journal of urology, 2014, Volume: 191, Issue:5 Topics: 5-Methylcytosine; Aging; Cytosine; DNA; DNA Methylation; Humans; Male; Paternal Age; Spermatozoa	2014
Environmental enrichment modulates 5-hydroxymethylcytosine dynamics in hippocampus. Genomics, 2014, Volume: 104, Issue:5 Topics: 5-Methylcytosine; Aging; Animals; Cytosine; DNA Methylation; Gene Expression Regulation; Gene-Environment Interaction; Hippocampus; Learning; Mice	2014
5-Hydroxymethylcytosine, the "Sixth Base", during brain development and ageing. Journal of neural transmission (Vienna, Austria : 1996), 2015, Volume: 122, Issue:7 Topics: 5-Methylcytosine; Adolescent; Adult; Aged; Aged, 80 and over; Aging; Analysis of Variance; Animals; Animals, Newborn; Brain; Cytosine; Female; Fetus; Gestational Age; Humans; Male; Mice; Mice, Inbred C57BL; Middle Aged; Phosphopyruvate Hydratase; Young Adult	2015
Dynamic changes of DNA epigenetic marks in mouse oocytes during natural and accelerated aging. The international journal of biochemistry & cell biology, 2015, Volume: 67 Topics: 5-Methylcytosine; Aging; Animals; Cellular Senescence; Cyclohexenes; Cytosine; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Epigenesis, Genetic; Female; Histones; Injections, Intraperitoneal; Mice; Mice, Inbred C57BL; Oocytes; Ovary; Protein Isoforms; Proto-Oncogene Proteins; Thymine DNA Glycosylase; Vinyl Compounds	2015
5-Formylcytosine can be a stable DNA modification in mammals. Nature chemical biology, 2015, Volume: 11, Issue:8 Topics: 5-Methylcytosine; Aging; Animals; Animals, Newborn; Brain; Cytosine; DNA; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Gene Expression Regulation, Developmental; Half-Life; Liver; Mice; Mice, Inbred C57BL; Myocardium	2015
Epigenetic modifications in mouse cerebellar Purkinje cells: effects of aging, caloric restriction, and overexpression of superoxide dismutase 1 on 5-methylcytosine and 5-hydroxymethylcytosine. Neurobiology of aging, 2015, Volume: 36, Issue:11 Topics: 5-Methylcytosine; Aging; Animals; Caloric Restriction; Cytosine; DNA Methylation; Epigenesis, Genetic; Gene Expression; Immunohistochemistry; Mice, Inbred C57BL; Purkinje Cells; Superoxide Dismutase; Superoxide Dismutase-1	2015
Profiling of methylation and demethylation pathways during brain development and ageing. Journal of neural transmission (Vienna, Austria : 1996), 2016, Volume: 123, Issue:3 Topics: 5-Methylcytosine; Aging; Animals; Brain; Cytosine; DNA Methylation; Epigenesis, Genetic; Female; Immunohistochemistry; Male; Mice; Mice, Inbred C57BL; Polymerase Chain Reaction; Transcriptome	2016
Bisulfite oligonucleotide-capture sequencing for targeted base- and strand-specific absolute 5-methylcytosine quantitation. Age (Dordrecht, Netherlands), 2016, Volume: 38, Issue:3 Topics: 5-Methylcytosine; Aging; Animals; DNA; DNA Methylation; Epigenesis, Genetic; Rats; Sequence Analysis, DNA; Sulfites	2016
Genome-wide alteration of 5-hydroxymenthylcytosine in a mouse model of Alzheimer's disease. BMC genomics, 2016, 05-20, Volume: 17 Topics: 5-Methylcytosine; Aging; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Animals; Cell Line; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Genome-Wide Association Study; Humans; Mice; Mice, Transgenic	2016
Age-associated hydroxymethylation in human bone-marrow mesenchymal stem cells. Journal of translational medicine, 2016, 07-08, Volume: 14, Issue:1 Topics: 5-Methylcytosine; Adolescent; Adult; Aged; Aged, 80 and over; Aging; Bone Marrow Cells; Child; Child, Preschool; Chromatin; CpG Islands; DNA Methylation; Genome, Human; Genomics; Humans; Mesenchymal Stem Cells; Middle Aged; Young Adult	2016
Analysis of the machinery and intermediates of the 5hmC-mediated DNA demethylation pathway in aging on samples from the MARK-AGE Study. Aging, 2016, 08-29, Volume: 8, Issue:9 Topics: 5-Methylcytosine; Adult; Aged; Aging; Dioxygenases; DNA Methylation; Female; Gene Expression; Gene Expression Regulation; Humans; Leukocytes, Mononuclear; Male; Middle Aged; Mixed Function Oxygenases; Proto-Oncogene Proteins	2016
Distinct cellular and molecular environments support aging-related DNA methylation changes in the substantia nigra. Epigenomics, 2017, Volume: 9, Issue:1 Topics: 5-Methylcytosine; Aging; Animals; DNA (Cytosine-5-)-Methyltransferases; DNA Methylation; Epigenesis, Genetic; Ketoglutaric Acids; Male; Mice; Mice, Inbred C57BL; Substantia Nigra; Succinic Acid	2017
Correlated 5-Hydroxymethylcytosine (5hmC) and Gene Expression Profiles Underpin Gene and Organ-Specific Epigenetic Regulation in Adult Mouse Brain and Liver. PloS one, 2017, Volume: 12, Issue:1 Topics: 5-Methylcytosine; Aging; Animals; Cerebellum; Cerebral Cortex; DNA Methylation; Embryo, Mammalian; Epigenesis, Genetic; Female; Gene Expression Regulation, Developmental; Genes, Essential; Genome; Hippocampus; Hypothalamus; Liver; Male; Mice; Mitochondrial Proteins; Organ Specificity; Ribosomal Proteins; Sequence Analysis, RNA; Sex Chromosomes; Thalamus; Transcriptome	2017
Promoter methylation and age-related downregulation of Klotho in rhesus monkey. Age (Dordrecht, Netherlands), 2012, Volume: 34, Issue:6 Topics: 5-Methylcytosine; Aging; Animals; Brain; Cell Line; Cytosine; DNA Methylation; Down-Regulation; Epigenesis, Genetic; Female; Gene Expression Regulation; Glucuronidase; Klotho Proteins; Macaca mulatta; Male; Promoter Regions, Genetic; RNA, Messenger; Transcription Factors	2012
5-hmC-mediated epigenetic dynamics during postnatal neurodevelopment and aging. Nature neuroscience, 2011, Oct-30, Volume: 14, Issue:12 Topics: 5-Methylcytosine; Aging; Analysis of Variance; Animals; Animals, Newborn; Cerebellum; Chromosome Deletion; Chromosome Mapping; Cytosine; Disease Models, Animal; DNA Methylation; Epigenomics; Gene Expression Regulation, Developmental; Hippocampus; Humans; Immunoprecipitation; Methyl-CpG-Binding Protein 2; Mice; Mice, Inbred C57BL; Mice, Transgenic; Molecular Sequence Data; Organ Specificity; Phosphopyruvate Hydratase; Rett Syndrome; X Chromosome	2011
Methylation on the mind. Nature neuroscience, 2011, Nov-23, Volume: 14, Issue:12 Topics: 5-Methylcytosine; Aging; Animals; Cerebellum; Cytosine; Epigenomics; Gene Expression Regulation, Developmental; Hippocampus; Humans	2011
The role of 5-hydroxymethylcytosine in aging and Alzheimer's disease: current status and prospects for future studies. Current Alzheimer research, 2012, Volume: 9, Issue:5 Topics: 5-Methylcytosine; Aging; Alzheimer Disease; Animals; Cytosine; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Humans; Translocation, Genetic	2012
Effect of aging on 5-hydroxymethylcytosine in the mouse hippocampus. Restorative neurology and neuroscience, 2012, Volume: 30, Issue:3 Topics: 5-Methylcytosine; Aging; Alzheimer Disease; Animals; Arachidonate 5-Lipoxygenase; Cytosine; Disease Models, Animal; DNA Methylation; Epigenesis, Genetic; Hippocampus; Male; Mice; Mice, Inbred C57BL; Up-Regulation	2012
Effect of aging on 5-hydroxymethylcytosine in brain mitochondria. Neurobiology of aging, 2012, Volume: 33, Issue:12 Topics: 5-Methylcytosine; Age Factors; Aging; Analysis of Variance; Animals; Animals, Newborn; Brain; Cells, Cultured; Cytosine; Dioxygenases; DNA (Cytosine-5-)-Methyltransferase 1; DNA (Cytosine-5-)-Methyltransferases; DNA-Binding Proteins; DNA, Mitochondrial; Enzyme-Linked Immunosorbent Assay; Gene Expression Regulation, Developmental; Laser Capture Microdissection; Male; Methyltransferases; Mice; Mice, Inbred C57BL; Mitochondria; Neurons; Proto-Oncogene Proteins	2012
Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis. Nature genetics, 2012, Volume: 44, Issue:11 Topics: 5-Methylcytosine; Aging; Dioxygenases; DNA Methylation; DNA-Binding Proteins; Exome; Female; Hematopoiesis; Humans; Proto-Oncogene Proteins; X Chromosome Inactivation	2012
TLC-based detection of methylated cytosine: application to aging epigenetics. Biogerontology, 2007, Volume: 8, Issue:6 Topics: 5-Methylcytosine; Adenosine Triphosphate; Aging; Cell Line; Cellular Senescence; Chromatography, Thin Layer; DNA Methylation; Epigenesis, Genetic; Fibroblasts; Humans; Hydrolysis; Phosphorus Radioisotopes; Reproducibility of Results	2007
Characterization of DNA methylation in the rat. Biochimica et biophysica acta, 1982, Dec-31, Volume: 699, Issue:3 Topics: 5-Methylcytosine; Aging; Animals; Base Composition; Base Sequence; Cell Differentiation; Cell Line; Cytosine; DNA; DNA Restriction Enzymes; Embryo, Mammalian; Kidney; Liver; Methylation; Organ Specificity; Rats; Rats, Inbred Strains	1982
The biological significance of meiosis. Symposia of the Society for Experimental Biology, 1984, Volume: 38 Topics: 5-Methylcytosine; Aging; Base Sequence; Cytosine; DNA (Cytosine-5-)-Methyltransferases; DNA Repair; Gene Conversion; Meiosis; Mutation; Plants; Recombination, Genetic; Reproduction; Saccharomyces cerevisiae; Selection, Genetic	1984
DNA methylation decreases in aging but not in immortal cells. Science (New York, N.Y.), 1983, Jun-03, Volume: 220, Issue:4601 Topics: 5-Methylcytosine; Aging; Animals; Cell Division; Cell Line; Cricetinae; Cytosine; DNA; Fibroblasts; Humans; Mesocricetus; Methylation; Mice; Time Factors	1983
5-methylcytosine is present in the 5' flanking region of Ha-ras in mouse liver and increases with ageing. International journal of cancer, 1997, Jul-29, Volume: 72, Issue:3 Topics: 5-Methylcytosine; Aging; Animals; Cytosine; Deoxyribonucleases, Type II Site-Specific; DNA Methylation; DNA Restriction Enzymes; Genes, ras; Humans; Liver; Male; Mice; Mice, Inbred C57BL; Polymerase Chain Reaction	1997
Decrease with age in methylcytosines in the promoter region of receptor for advanced glycated end products (RAGE) gene in autopsy human cortex. Brain research. Molecular brain research, 1999, Feb-19, Volume: 65, Issue:1 Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Aging; Base Sequence; Brain Chemistry; Cerebral Cortex; Cytosine; DNA Methylation; DNA Probes; Female; Glycation End Products, Advanced; Humans; Male; Middle Aged; Molecular Sequence Data; Promoter Regions, Genetic; Receptor for Advanced Glycation End Products; Receptors, Immunologic; Transcription, Genetic	1999
Reduction with age in methylcytosine in the promoter region -224 approximately -101 of the amyloid precursor protein gene in autopsy human cortex. Brain research. Molecular brain research, 1999, Jul-05, Volume: 70, Issue:2 Topics: 5-Methylcytosine; Adult; Aged; Aged, 80 and over; Aging; Amyloid beta-Protein Precursor; Autopsy; Base Composition; Base Sequence; Cerebral Cortex; Cytosine; DNA Methylation; Female; Humans; Male; Middle Aged; Molecular Sequence Data; Promoter Regions, Genetic; Repetitive Sequences, Nucleic Acid	1999
Through a glass, darkly: reflections of mutation from lacI transgenic mice. Genetics, 2000, Volume: 155, Issue:3 Topics: 5-Methylcytosine; Aging; Animals; Bacterial Proteins; Brain; Cell Division; CpG Islands; Cytosine; Deamination; DNA Methylation; DNA Mutational Analysis; Escherichia coli Proteins; Gene Frequency; Lac Repressors; Liver; Mice; Mice, Inbred C57BL; Mice, Transgenic; Models, Genetic; Repressor Proteins; Species Specificity; Transgenes	2000
Human lymphocytes aged in vivo have reduced levels of methylation in transcriptionally active and inactive DNA. Mutation research, 1989, Volume: 219, Issue:1 Topics: 5-Methylcytosine; Adult; Aged; Aging; Cytosine; DNA; Genes; Humans; Lymphocytes; Methylation; Transcription, Genetic	1989
[DNA methylation and interaction with glucocorticoid receptor complexes in the rat liver]. Biokhimiia (Moscow, Russia), 1987, Volume: 52, Issue:5 Topics: 5-Methylcytosine; Adrenalectomy; Aging; Animals; Cytosine; DNA; Female; Hydrocortisone; Liver; Methylation; Rats; Receptors, Glucocorticoid	1987
Caenorhabditis elegans DNA does not contain 5-methylcytosine at any time during development or aging. Nucleic acids research, 1986, Aug-26, Volume: 14, Issue:16 Topics: 5-Methylcytosine; Aging; Animals; Caenorhabditis; Chromatography, High Pressure Liquid; Crosses, Genetic; Cytosine; DNA; Nucleic Acid Hybridization; Species Specificity	1986