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5-methoxytryptamine and Muscle Contraction

5-methoxytryptamine has been researched along with Muscle Contraction in 27 studies

5-Methoxytryptamine: Serotonin derivative proposed as potentiator for hypnotics and sedatives.
5-methoxytryptamine : A member of the class of tryptamines that is the methyl ether derivative of serotonin.

Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.

Research Excerpts

ExcerptRelevanceReference
") dosing to rats."1.29Pharmacological characterization of FK1052, a dihydropyridoindole derivative, as a new serotonin 3 and 4 dual receptor antagonist. ( Kadowaki, M; Kohsaka, M; Mori, J; Nagakura, Y; Tokoro, K; Tomoi, M, 1993)
" In a solution containing 20 mM K+ 5-HT induced a biphasic dose-response curve (DRC) in intact arteries."1.28Serotonergic responses in rabbit ophthalmic artery: a pharmacological characterization. ( Uusitalo, H; van Breemen, C; Zschauer, A, 1991)

Research

Studies (27)

TimeframeStudies, this research(%)All Research%
pre-19905 (18.52)18.7374
1990's19 (70.37)18.2507
2000's1 (3.70)29.6817
2010's2 (7.41)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wainscott, DB1
Cohen, ML3
Schenck, KW1
Audia, JE1
Nissen, JS1
Baez, M2
Kursar, JD2
Lucaites, VL1
Nelson, DL1
Chai, W1
Chan, KY1
de Vries, R1
van den Bogeardt, AJ1
de Maeyer, JH1
Schuurkes, JA3
Villalón, CM1
Saxena, PR1
Danser, AH1
MaassenVanDenBrink, A1
Coupar, IM2
Irving, HR1
Manallack, DT1
Tan, YY1
Ayad, F1
Iulio, JD1
Tochon-Danguy, N1
Iskander, MN1
Forster, C1
Whalley, ET1
Ramírez, MJ1
Cenarruzabeitia, E1
Del Río, J1
Lasheras, B1
Cushing, DJ2
Schenck, K1
Gale, JD1
Grossman, CJ1
Whitehead, JW1
Oxford, AW1
Bunce, KT1
Humphrey, PP1
Nagakura, Y1
Kadowaki, M1
Tokoro, K1
Tomoi, M1
Mori, J1
Kohsaka, M1
Carter, D1
Champney, M1
Hwang, B1
Eglen, RM1
Ishizawa, M1
Kojima, S1
Shimo, Y1
Csillik-Perczel, V1
Bakonyi, A1
Yemane, T1
Vitalis, B1
Horvath, E1
Solyom, S1
Szekely, JI1
Harsing, LG1
Amemiya, N1
Hatta, S1
Takemura, H1
Ohshika, H1
Goldhill, J1
Porquet, MF1
Angel, I1
González, AA1
Puig, MM1
Pérez-Alvarez, V1
Morales-Ríos, MS1
Hong, E1
Joseph-Nathan, P1
Briejer, MR1
Mathis, C1
Hemedah, M1
Mitchelson, FJ1
O'Gara, BA1
Illuzzi, FA1
Chung, M1
Portnoy, AD1
Fraga, K1
Frieman, VB1
Kitazawa, T1
Yamada, Y1
Iwano, H1
Yokota, H1
Yuasa, A1
Taneike, T1
Huidobro-Toro, JP1
Huidobro, F1
Ruiz, M1
Rattan, S1
Goyal, RK1
Abramets, II1
Komissarov, IV1
Samoilovich, IM1
Shovtuta, VI1
Friedman, E1
Dallob, A1
Meulemans, AL1
Zschauer, A1
van Breemen, C1
Uusitalo, H1

Other Studies

27 other studies available for 5-methoxytryptamine and Muscle Contraction

ArticleYear
Pharmacological characteristics of the newly cloned rat 5-hydroxytryptamine2F receptor.
    Molecular pharmacology, 1993, Volume: 43, Issue:3

    Topics: Animals; Binding Sites; Cell Line; Cloning, Molecular; Gastric Fundus; Inositol 1,4,5-Trisphosphate;

1993
Inotropic effects of prokinetic agents with 5-HT(4) receptor agonist actions on human isolated myocardial trabeculae.
    Life sciences, 2012, Apr-09, Volume: 90, Issue:13-14

    Topics: 5-Methoxytryptamine; Adolescent; Adult; Aged; Benzofurans; Calcium Channels; Child; Cisapride; Femal

2012
Assessment of the pharmacological properties of 5-methoxyindole derivatives at 5-HT4 receptors.
    The Journal of pharmacy and pharmacology, 2012, Volume: 64, Issue:8

    Topics: 5-Methoxytryptamine; Animals; Colon; Female; Gastrointestinal Transit; Guinea Pigs; Humans; Hydroxyl

2012
Comparison of the contraction produced by various tryptamine analogues on human basilar arterial and rat aortic strips in vitro.
    Cephalalgia : an international journal of headache, 1981, Volume: 1, Issue:4

    Topics: 5-Methoxytryptamine; Animals; Aorta, Thoracic; Basilar Artery; Female; Humans; Male; Muscle Contract

1981
Involvement of neurokinins in the non-cholinergic response to activation of 5-HT3 and 5-HT4 receptors in guinea-pig ileum.
    British journal of pharmacology, 1994, Volume: 111, Issue:2

    Topics: 5-Methoxytryptamine; Acetylcholine; Animals; Atropine; Autonomic Nervous System; Choline; Female; Gu

1994
Serotonin-induced contraction in canine coronary artery and saphenous vein: role of a 5-HT1D-like receptor.
    Life sciences, 1994, Volume: 54, Issue:22

    Topics: 5-Methoxytryptamine; Adrenergic alpha-Antagonists; Animals; Base Sequence; Blotting, Southern; Coron

1994
GR113808: a novel, selective antagonist with high affinity at the 5-HT4 receptor.
    British journal of pharmacology, 1994, Volume: 111, Issue:1

    Topics: 5-Methoxytryptamine; Animals; Benzamides; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Hete

1994
Serotonin-induced contraction in porcine coronary artery: use of ergolines to support vascular 5-hydroxytryptamine2-receptor heterogeneity.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:1

    Topics: 5-Methoxytryptamine; Animals; Coronary Vessels; Endothelium, Vascular; Ergolines; In Vitro Technique

1993
Pharmacological characterization of FK1052, a dihydropyridoindole derivative, as a new serotonin 3 and 4 dual receptor antagonist.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 265, Issue:2

    Topics: 5-Methoxytryptamine; Acetylcholine; Animals; Bradycardia; Electric Stimulation; Guinea Pigs; Histami

1993
Characterization of a postjunctional 5-HT receptor mediating relaxation of guinea-pig isolated ileum.
    European journal of pharmacology, 1995, Jul-14, Volume: 280, Issue:3

    Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Cloning, Molecular; Drug Inter

1995
Inhibitory action of 5-hydroxytryptamine on propulsive activity of the guinea-pig isolated colon.
    Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology, 1996, Volume: 114, Issue:1

    Topics: 5-Methoxytryptamine; Animals; Colon; Dose-Response Relationship, Drug; Guinea Pigs; In Vitro Techniq

1996
Investigation into the 5-hydroxytryptamine-induced atropine-resistant neurogenic contraction of guinea-pig proximal colon.
    British journal of pharmacology, 1996, Volume: 117, Issue:8

    Topics: 5-Methoxytryptamine; Animals; Atropine; Colon; Dipeptides; Dose-Response Relationship, Drug; Guinea

1996
GYKI-46 903, a non-competitive antagonist for 5-HT3 receptors.
    Pharmacology & toxicology, 1996, Volume: 79, Issue:1

    Topics: 5-Methoxytryptamine; Animals; Binding, Competitive; Bradycardia; Bridged Bicyclo Compounds, Heterocy

1996
Characterization of the contractile response induced by 5-methoxytryptamine in rat stomach fundus strips.
    European journal of pharmacology, 1996, Dec-30, Volume: 318, Issue:2-3

    Topics: 4-Aminobenzoic Acid; 5-Methoxytryptamine; Acetylcholine; Animals; Atropine; Dose-Response Relationsh

1996
Post-synaptic 5-HT4 receptor modulation of tachykinergic excitation of rat oesophageal tunica muscularis mucosae.
    European journal of pharmacology, 1997, Apr-04, Volume: 323, Issue:2-3

    Topics: 5-Methoxytryptamine; Animals; Carbachol; Esophagus; In Vitro Techniques; Male; Muscle Contraction; M

1997
Ondansetron facilitates neuromuscular transmission in the guinea-pig ileum.
    European journal of pharmacology, 1997, Jun-11, Volume: 328, Issue:2-3

    Topics: 5-Methoxytryptamine; Animals; Electric Stimulation; Guinea Pigs; Ileum; In Vitro Techniques; Indoles

1997
Synthesis of 3-amino-2-(3-indolyl)propanol and propanoate derivatives and preliminary cardiovascular evaluation in rats.
    The Journal of pharmacy and pharmacology, 1997, Volume: 49, Issue:3

    Topics: 5-Methoxytryptamine; Animals; Antihypertensive Agents; Basilar Artery; Blood Pressure; Decerebrate S

1997
5-HT receptor types in the rat ileum longitudinal muscle: focus on 5-HT2 receptors mediating contraction.
    Neurogastroenterology and motility, 1997, Volume: 9, Issue:4

    Topics: 5-Methoxytryptamine; Animals; Female; Gastrointestinal Motility; Ileum; In Vitro Techniques; Ketanse

1997
[3H]-Mesulergine labels 5-HT7 sites in rat brain and guinea-pig ileum but not rat jejunum.
    British journal of pharmacology, 1999, Volume: 126, Issue:1

    Topics: 5-Methoxytryptamine; Animals; Binding Sites; Binding, Competitive; Brain; Dose-Response Relationship

1999
Serotonin induces four pharmacologically separable contractile responses in the pharynx of the leech Hirudo medicinalis.
    General pharmacology, 1999, Volume: 32, Issue:6

    Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Dose-Response Re

1999
Smooth muscle layer-dependent distribution of 5-hydroxytryptamine(7) receptor in the porcine myometrium.
    British journal of pharmacology, 2000, Volume: 130, Issue:1

    Topics: 5-Methoxytryptamine; Animals; Cyclic AMP; Female; Muscle Contraction; Muscle, Smooth; Myometrium; Re

2000
N-Chloroacetyl 5-methoxytryptamine (isamide): a selective antagonist of 5-hydroxytryptamine in the rat uterus.
    The Journal of pharmacy and pharmacology, 1979, Volume: 31, Issue:6

    Topics: 5-Methoxytryptamine; Animals; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth;

1979
Effects of 5-hydroxytryptamine on the lower esophageal sphincter in vivo: evidence for multiple sites of action.
    The Journal of clinical investigation, 1977, Volume: 59, Issue:1

    Topics: 5-Methoxytryptamine; Animals; Dose-Response Relationship, Drug; Esophagogastric Junction; Methysergi

1977
[Effect of serotonin on smooth muscle].
    Biulleten' eksperimental'noi biologii i meditsiny, 1977, Volume: 83, Issue:2

    Topics: 5-Methoxytryptamine; Animals; Calcium; Cold Temperature; Dose-Response Relationship, Drug; Male; Mus

1977
Enhanced serotonin receptor activity after chronic treatment with imipramine or amitriptyline.
    Communications in psychopharmacology, 1979, Volume: 3, Issue:2

    Topics: 5-Methoxytryptamine; Amitriptyline; Animals; Brain; Imipramine; Male; Methysergide; Mice; Muscle Con

1979
Is the action of cisapride on the guinea-pig ileum mediated via 5-HT4 receptors?
    European journal of pharmacology, 1992, Feb-25, Volume: 212, Issue:1

    Topics: 5-Methoxytryptamine; Animals; Cisapride; Dose-Response Relationship, Drug; Drug Interactions; Female

1992
Serotonergic responses in rabbit ophthalmic artery: a pharmacological characterization.
    The American journal of physiology, 1991, Volume: 261, Issue:6 Pt 2

    Topics: 5-Methoxytryptamine; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Dose-Response Relationship, Dr

1991