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5-methoxytryptamine and Disease Models, Animal

5-methoxytryptamine has been researched along with Disease Models, Animal in 9 studies

5-Methoxytryptamine: Serotonin derivative proposed as potentiator for hypnotics and sedatives.
5-methoxytryptamine : A member of the class of tryptamines that is the methyl ether derivative of serotonin.

Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.

Research Excerpts

ExcerptRelevanceReference
"Perinatal administration of serotonin (5HT) agonist 5-methoxytryptamine (5MT) induces developmental hyperserotonemia (DHS; elevated blood serotonin) and produces behavioral and neurochemical changes in rats relevant to Autism Spectrum Disorder (ASD), such as oxytocin dysregulation."7.88Serotonin receptor regulation as a potential mechanism for sexually dimorphic oxytocin dysregulation in a model of Autism. ( Edwards, KA; Madden, AMK; Zup, SL, 2018)
"Perinatal administration of serotonin (5HT) agonist 5-methoxytryptamine (5MT) induces developmental hyperserotonemia (DHS; elevated blood serotonin) and produces behavioral and neurochemical changes in rats relevant to Autism Spectrum Disorder (ASD), such as oxytocin dysregulation."3.88Serotonin receptor regulation as a potential mechanism for sexually dimorphic oxytocin dysregulation in a model of Autism. ( Edwards, KA; Madden, AMK; Zup, SL, 2018)
"Melatonin has been shown to prevent the progressive degeneration produced by neurotoxins employed in experimental models to mimic the degenerative events in various neuropsychiatric disease states."2.43The role of ML-23 and other melatonin analogues in the treatment and management of Parkinson's disease. ( Willis, GL, 2005)
"Autism is classified as a pervasive developmental disorder, with several cardinal features including sensory disturbances, obsessive-compulsive-like behavior, lack of bonding to caregivers and motor disturbances."1.31Behavioral and magnetic resonance spectroscopic studies in the rat hyperserotonemic model of autism. ( Borella, A; Huang, W; Johnstone, F; Kahne, D; Shapiro, L; Tudorica, A; Whitaker-Azmitia, PM, 2002)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's4 (44.44)29.6817
2010's3 (33.33)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Solinski, HJ1
Dranchak, P1
Oliphant, E1
Gu, X1
Earnest, TW1
Braisted, J1
Inglese, J1
Hoon, MA1
Abrams, RPM1
Yasgar, A1
Teramoto, T1
Lee, MH1
Dorjsuren, D1
Eastman, RT1
Malik, N1
Zakharov, AV1
Li, W1
Bachani, M1
Brimacombe, K1
Steiner, JP1
Hall, MD1
Balasubramanian, A1
Jadhav, A1
Padmanabhan, R1
Simeonov, A1
Nath, A1
Edwards, KA1
Madden, AMK1
Zup, SL1
Horvath, G1
Joo, G1
Kekesi, G1
Farkas, I1
Tuboly, G1
Petrovszki, Z1
Benedek, G1
Willis, GL2
Kennedy, GA1
Bravo, G1
Ibarra, A1
Guizar-SahagĂșn, G1
Rojas, G1
Hong, E1
Teramoto, Y1
Urano, T1
Nagai, N1
Takada, Y1
Ikeda, K1
Takada, A1
Kahne, D1
Tudorica, A1
Borella, A1
Shapiro, L1
Johnstone, F1
Huang, W1
Whitaker-Azmitia, PM1

Reviews

2 reviews available for 5-methoxytryptamine and Disease Models, Animal

ArticleYear
The implementation of acute versus chronic animal models for treatment discovery in Parkinson's disease.
    Reviews in the neurosciences, 2004, Volume: 15, Issue:1

    Topics: 5-Methoxytryptamine; Animals; Antiparkinson Agents; Disease Models, Animal; Dopamine; Dose-Response

2004
The role of ML-23 and other melatonin analogues in the treatment and management of Parkinson's disease.
    Drug news & perspectives, 2005, Volume: 18, Issue:7

    Topics: 5-Methoxytryptamine; Animals; Antiparkinson Agents; Disease Models, Animal; Humans; Levodopa; Melato

2005

Other Studies

7 other studies available for 5-methoxytryptamine and Disease Models, Animal

ArticleYear
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
    Science translational medicine, 2019, 07-10, Volume: 11, Issue:500

    Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S

2019
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
    Proceedings of the National Academy of Sciences of the United States of America, 2020, 12-08, Volume: 117, Issue:49

    Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr

2020
Serotonin receptor regulation as a potential mechanism for sexually dimorphic oxytocin dysregulation in a model of Autism.
    Brain research, 2018, 12-15, Volume: 1701

    Topics: 5-Methoxytryptamine; Animals; Autism Spectrum Disorder; Autistic Disorder; Disease Models, Animal; F

2018
Inhibition of itch-related responses at spinal level in rats.
    Acta physiologica Hungarica, 2011, Volume: 98, Issue:4

    Topics: 5-Methoxytryptamine; Analgesics; Animals; Behavior, Animal; Disease Models, Animal; Drug Interaction

2011
Indorenate improves motor function in rats with chronic spinal cord injury.
    Basic & clinical pharmacology & toxicology, 2007, Volume: 100, Issue:1

    Topics: 5-Methoxytryptamine; Animals; Chronic Disease; Contusions; Disease Models, Animal; Exploratory Behav

2007
Plasma levels of 5-HT and 5-HIAA increased after intestinal ischemia/reperfusion in rats.
    The Japanese journal of physiology, 1998, Volume: 48, Issue:5

    Topics: 5-Methoxytryptamine; Animals; Dioxanes; Disease Models, Animal; Hydroxyindoleacetic Acid; Intestines

1998
Behavioral and magnetic resonance spectroscopic studies in the rat hyperserotonemic model of autism.
    Physiology & behavior, 2002, Volume: 75, Issue:3

    Topics: 5-Methoxytryptamine; Acoustic Stimulation; Animals; Autistic Disorder; Behavior, Animal; Birth Weigh

2002