5-methoxypsoralen has been researched along with Vitiligo in 7 studies
5-Methoxypsoralen: A linear furanocoumarin that has phototoxic and anti-inflammatory properties, with effects similar to METHOXSALEN. It is used in PUVA THERAPY for the treatment of PSORIASIS.
5-methoxypsoralen : A 5-methoxyfurocoumarin that is psoralen substituted by a methoxy group at position 5.
Vitiligo: A disorder consisting of areas of macular depigmentation, commonly on extensor aspects of extremities, on the face or neck, and in skin folds. Age of onset is often in young adulthood and the condition tends to progress gradually with lesions enlarging and extending until a quiescent state is reached.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5-Methoxypsoralen, a naturally occurring linear furocoumarin, has been successfully used in combination with ultraviolet (UV) A irradiation [psoralen plus UV (PUVA)] to manage psoriasis and vitiligo." | 8.80 | 5-Methoxypsoralen. A review of its effects in psoriasis and vitiligo. ( Goa, KL; McNeely, W, 1998) |
| "Pimpinellin was recently found to be phototoxic, but an action spectrum of sphondin is reported for the first time." | 5.27 | Phototoxicity from furocoumarins (psoralens) of Heracleum laciniatum in a patient with vitiligo. Action spectrum studies on bergapten, pimpinellin, angelicin and sphondin. ( Kavli, G; Midelfart, K; Raa, J; Volden, G, 1983) |
| "5-Methoxypsoralen, a naturally occurring linear furocoumarin, has been successfully used in combination with ultraviolet (UV) A irradiation [psoralen plus UV (PUVA)] to manage psoriasis and vitiligo." | 4.80 | 5-Methoxypsoralen. A review of its effects in psoriasis and vitiligo. ( Goa, KL; McNeely, W, 1998) |
| "5-methoxypsoralen (bergapten) has been used in the treatment of psoriasis and vitiligo, and as a sun tanning accelerator." | 3.77 | Percutaneous penetration of 5-methoxypsoralen in rhesus monkeys. ( Konda, S; Maibach, HI, 2011) |
| "Pimpinellin was recently found to be phototoxic, but an action spectrum of sphondin is reported for the first time." | 1.27 | Phototoxicity from furocoumarins (psoralens) of Heracleum laciniatum in a patient with vitiligo. Action spectrum studies on bergapten, pimpinellin, angelicin and sphondin. ( Kavli, G; Midelfart, K; Raa, J; Volden, G, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 4 (57.14) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| da Silva, VB | 1 |
| Kawano, DF | 1 |
| Carvalho, I | 1 |
| da Conceição, EC | 1 |
| de Freitas, O | 1 |
| da Silva, CH | 1 |
| Konda, S | 1 |
| Maibach, HI | 1 |
| Kavli, G | 1 |
| Midelfart, K | 1 |
| Raa, J | 1 |
| Volden, G | 1 |
| Mignot, B | 1 |
| Guillaume, Y | 1 |
| Makki, S | 1 |
| Murret, E | 1 |
| Cavalli, E | 1 |
| Truong, TT | 1 |
| Thomassin, M | 1 |
| Guinchard, C | 1 |
| McNeely, W | 1 |
| Goa, KL | 1 |
| Shephard, SE | 1 |
| Panizzon, RG | 1 |
1 review available for 5-methoxypsoralen and Vitiligo
| Article | Year |
|---|---|
5-Methoxypsoralen. A review of its effects in psoriasis and vitiligo.
Topics: 5-Methoxypsoralen; Humans; Methoxsalen; Psoriasis; Vitiligo | 1998 |
6 other studies available for 5-methoxypsoralen and Vitiligo
| Article | Year |
|---|---|
Psoralen and bergapten: in silico metabolism and toxicophoric analysis of drugs used to treat vitiligo.
Topics: 5-Methoxypsoralen; Animals; Biotransformation; Computational Biology; Computer Simulation; Drug Disc | 2009 |
Percutaneous penetration of 5-methoxypsoralen in rhesus monkeys.
Topics: 5-Methoxypsoralen; Administration, Cutaneous; Animals; Carbon Isotopes; Injections, Intramuscular; M | 2011 |
Phototoxicity from furocoumarins (psoralens) of Heracleum laciniatum in a patient with vitiligo. Action spectrum studies on bergapten, pimpinellin, angelicin and sphondin.
Topics: 5-Methoxypsoralen; Adult; Anticonvulsants; Female; Furocoumarins; Humans; Intercalating Agents; Isom | 1983 |
British Photodermatology Group guidelines for PUVA.
Topics: 5-Methoxypsoralen; Cataract; Dermatitis, Atopic; Humans; Methoxsalen; Mycosis Fungoides; Psoriasis; | 1994 |
High-performance thin-layer chromatographic determination of 5-methoxypsoralen in serum from patients.
Topics: 5-Methoxypsoralen; Chromatography, Thin Layer; Humans; Methoxsalen; Psoriasis; PUVA Therapy; Reprodu | 1997 |
Carcinogenic risk of bath PUVA in comparison to oral PUVA therapy.
Topics: 5-Methoxypsoralen; Administration, Oral; Administration, Topical; Baths; DNA Adducts; Female; Humans | 1999 |