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5-methoxypsoralen and Inflammation

5-methoxypsoralen has been researched along with Inflammation in 9 studies

5-Methoxypsoralen: A linear furanocoumarin that has phototoxic and anti-inflammatory properties, with effects similar to METHOXSALEN. It is used in PUVA THERAPY for the treatment of PSORIASIS.
5-methoxypsoralen : A 5-methoxyfurocoumarin that is psoralen substituted by a methoxy group at position 5.

Inflammation: A pathological process characterized by injury or destruction of tissues caused by a variety of cytologic and chemical reactions. It is usually manifested by typical signs of pain, heat, redness, swelling, and loss of function.

Research Excerpts

ExcerptRelevanceReference
" Analog 19 was a more potent anti-inflammatory agent than the reference compound indomethacin and of comparable cytocompatibility to 8-MOP whereas analog 24 was a weaker inhibitor of inflammation than indomethacin and significantly more cytotoxic than 8-MOP."3.79Syntheses and evaluation of the antioxidant activity of novel methoxypsoralen derivatives. ( Athanassopoulos, CM; Avgoustakis, K; Bariamis, SE; Hadjipavlou-Litina, D; Kontogiorgis, C; Marin, M; Papaioannou, D; Romeo, G; Sindona, G; Tsimali, Z, 2013)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (11.11)18.2507
2000's0 (0.00)29.6817
2010's6 (66.67)24.3611
2020's2 (22.22)2.80

Authors

AuthorsStudies
Saunders, MJ1
Edwards, BS1
Zhu, J1
Sklar, LA1
Graves, SW1
Bariamis, SE1
Marin, M1
Athanassopoulos, CM1
Kontogiorgis, C1
Tsimali, Z1
Papaioannou, D1
Sindona, G1
Romeo, G1
Avgoustakis, K1
Hadjipavlou-Litina, D1
Luo, T1
Jia, X1
Feng, WD1
Wang, JY1
Xie, F1
Kong, LD1
Wang, XJ1
Lian, R1
Liu, X1
Chu, YJ1
Wang, Y2
Xu, AL1
Jiang, Y1
Nguyen, TV1
Jin, J1
Yu, ZN1
Song, CH1
Chai, OH1
Yang, Y1
Zheng, K1
Mei, W1
Yu, C1
Yu, B1
Deng, S1
Hu, J1
Singh, G2
Kaur, A1
Kaur, J1
Bhatti, MS1
Singh, P2
Bhatti, R2
He, Y1
Zisan, Z1
Lu, Z1
Zheng, L1
Zhao, J1
Singh, A1
Muret, P1
Makki, S1
Urien, S1
Agache, P1
Bechtel, P1
Tillement, JP1

Other Studies

9 other studies available for 5-methoxypsoralen and Inflammation

ArticleYear
Microsphere-based flow cytometry protease assays for use in protease activity detection and high-throughput screening.
    Current protocols in cytometry, 2010, Volume: Chapter 13

    Topics: Animals; Biotinylation; Flow Cytometry; Fluorescence Resonance Energy Transfer; Green Fluorescent Pr

2010
Syntheses and evaluation of the antioxidant activity of novel methoxypsoralen derivatives.
    European journal of medicinal chemistry, 2013, Volume: 60

    Topics: Anti-Inflammatory Agents; Antioxidants; Dose-Response Relationship, Drug; Furocoumarins; Glycine max

2013
Bergapten inhibits NLRP3 inflammasome activation and pyroptosis via promoting mitophagy.
    Acta pharmacologica Sinica, 2023, Volume: 44, Issue:9

    Topics: 5-Methoxypsoralen; Animals; Caspase 1; Inflammasomes; Inflammation; Interleukin-1beta; Mice; Mitopha

2023
Bergapten ameliorates combined allergic rhinitis and asthma syndrome after PM2.5 exposure by balancing Treg/Th17 expression and suppressing STAT3 and MAPK activation in a mouse model.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2023, Volume: 164

    Topics: 5-Methoxypsoralen; Animals; Asthma; Cytokines; Disease Models, Animal; Inflammation; Mice; Mice, Inb

2023
Anti-inflammatory and proresolution activities of bergapten isolated from the roots of Ficus hirta in an in vivo zebrafish model.
    Biochemical and biophysical research communications, 2018, 02-05, Volume: 496, Issue:2

    Topics: 5-Methoxypsoralen; Animals; Anti-Inflammatory Agents; Disease Models, Animal; Female; Ficus; Inflamm

2018
Bergapten inhibits chemically induced nociceptive behavior and inflammation in mice by decreasing the expression of spinal PARP, iNOS, COX-2 and inflammatory cytokines.
    Inflammopharmacology, 2019, Volume: 27, Issue:4

    Topics: 5-Methoxypsoralen; Analgesics; Animals; Anti-Inflammatory Agents; Carrageenan; Cyclooxygenase 2; Cyt

2019
Bergapten alleviates osteoarthritis by regulating the ANP32A/ATM signaling pathway.
    FEBS open bio, 2019, Volume: 9, Issue:6

    Topics: 5-Methoxypsoralen; Animals; Anti-Inflammatory Agents; Ataxia Telangiectasia Mutated Proteins; Cell P

2019
Bergapten Ameliorates Vincristine-Induced Peripheral Neuropathy by Inhibition of Inflammatory Cytokines and NFκB Signaling.
    ACS chemical neuroscience, 2019, 06-19, Volume: 10, Issue:6

    Topics: 5-Methoxypsoralen; Animals; Anti-Inflammatory Agents; Antineoplastic Agents, Phytogenic; Cytokines;

2019
Binding of 5-methoxypsoralen to blood fractions. Influence of albumin and free fatty acids: an in vitro study.
    Skin pharmacology : the official journal of the Skin Pharmacology Society, 1993, Volume: 6, Issue:1

    Topics: 5-Methoxypsoralen; Blood Proteins; Erythrocytes; Extracellular Space; Fatty Acids; gamma-Globulins;

1993