5-methoxypsoralen has been researched along with Dermatitis, Contact, Phototoxic in 10 studies
5-Methoxypsoralen: A linear furanocoumarin that has phototoxic and anti-inflammatory properties, with effects similar to METHOXSALEN. It is used in PUVA THERAPY for the treatment of PSORIASIS.
5-methoxypsoralen : A 5-methoxyfurocoumarin that is psoralen substituted by a methoxy group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A patient developed severe bullous phototoxic contact dermatitis caused by Ruta graveolens L." | 2.40 | [Bullous phototoxic contact dermatitis caused by Ruta graveolens L. (garden rue), Rutaceae. Case report and review of literature]. ( Schempp, CM; Schöpf, E; Simon, JC, 1999) |
| " Seventy-two hours after UVA exposure minimal phototoxic doses (MPD) were defined visually and the intensity of the erythema response was also assessed by using a narrowband spectrophotometer The MPD and the dose-response curves for erythema response of the gels and creams were compared with those of the bath." | 1.33 | Phototoxicity of new psoralen-containing gels and creams versus bath PUVA. ( Leenutaphong, V; Nimkulrat, P; Sudtim, S, 2005) |
| "In such conditions, the phototoxicity assay is much more sensitive, so that the model is expected to be of great interest for the detection not only of strong but also of weak phototoxic compounds." | 1.31 | Development of a highly sensitive in vitro phototoxicity assay using the SkinEthic reconstructed human epidermis. ( Barrault, C; Bernard, FX; De Wever, B; Deguercy, A; Rosdy, M, 2000) |
| "Histopathology revealed skin phototoxicity of compounds which lacked erythemogenic activity by visual scoring." | 1.30 | Antiproliferative activity and phototoxicity of some methyl derivatives of 5-methoxypsoralen and 5-methoxyangelicin. ( Conconi, MT; Montesi, F; Parnigotto, PP, 1998) |
| "The photogenotoxicity of this suction blister fluid containing 5-methoxypsoralen and also other ingredients of the tanning preparation was assayed on yeast cells and was found to be rather low." | 1.29 | Evaluation of phototoxic and photogenotoxic risk associated with the use of photosensitizers in suntan preparations: application to tanning preparations containing bergamot oil. ( Averbeck, D; Dubertret, L; Morlière, P; Moysan, A, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (60.00) | 18.2507 |
| 2000's | 3 (30.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maciel, B | 1 |
| Moreira, P | 1 |
| Carmo, H | 1 |
| Gonçalo, M | 1 |
| Lobo, JMS | 1 |
| Almeida, IF | 1 |
| Marrot, L | 1 |
| Labarussiat, A | 1 |
| Perez, P | 1 |
| Meunier, JR | 1 |
| Nimkulrat, P | 1 |
| Leenutaphong, V | 1 |
| Sudtim, S | 1 |
| Yasui, Y | 1 |
| Hirone, T | 1 |
| Moysan, A | 1 |
| Morlière, P | 1 |
| Averbeck, D | 1 |
| Dubertret, L | 1 |
| Knudsen, EA | 1 |
| Bech-Thomsen, N | 1 |
| Wulf, HC | 1 |
| Conconi, MT | 1 |
| Montesi, F | 1 |
| Parnigotto, PP | 1 |
| Clark, SM | 1 |
| Wilkinson, SM | 1 |
| Schempp, CM | 1 |
| Schöpf, E | 1 |
| Simon, JC | 1 |
| Bernard, FX | 1 |
| Barrault, C | 1 |
| Deguercy, A | 1 |
| De Wever, B | 1 |
| Rosdy, M | 1 |
1 review available for 5-methoxypsoralen and Dermatitis, Contact, Phototoxic
| Article | Year |
|---|---|
[Bullous phototoxic contact dermatitis caused by Ruta graveolens L. (garden rue), Rutaceae. Case report and review of literature].
Topics: 5-Methoxypsoralen; Alkaloids; Anti-Infective Agents, Local; Carcinogens; Cross-Linking Reagents; Der | 1999 |
9 other studies available for 5-methoxypsoralen and Dermatitis, Contact, Phototoxic
| Article | Year |
|---|---|
Implementation of an in vitro methodology for phototoxicity evaluation in a human keratinocyte cell line.
Topics: 5-Methoxypsoralen; Animal Testing Alternatives; Animals; Aspirin; Biological Assay; Cell Line; Chlor | 2019 |
Use of the yeast Saccharomyces cerevisiae as a pre-screening approach for assessment of chemical-induced phototoxicity.
Topics: 5-Methoxypsoralen; Dermatitis, Phototoxic; Drug Evaluation, Preclinical; Methoxsalen; Saccharomyces | 2006 |
Phototoxicity of new psoralen-containing gels and creams versus bath PUVA.
Topics: 5-Methoxypsoralen; Administration, Topical; Adolescent; Adult; Aged; Baths; Dermatitis, Phototoxic; | 2005 |
Action spectrum for bergamot-oil phototoxicity measured by sunburn cell counting.
Topics: 5-Methoxypsoralen; Animals; Cell Count; Dermatitis, Phototoxic; Dose-Response Relationship, Radiatio | 1994 |
Evaluation of phototoxic and photogenotoxic risk associated with the use of photosensitizers in suntan preparations: application to tanning preparations containing bergamot oil.
Topics: 5-Methoxypsoralen; Blister; Dermatitis, Phototoxic; Gas Chromatography-Mass Spectrometry; Humans; Me | 1993 |
Ultraviolet A-induced photodegradation of 5-methoxypsoralen, 8-methoxypsoralen and psoralen reduces the biological effectiveness of the furocoumarins in vivo.
Topics: 5-Methoxypsoralen; Dermatitis, Phototoxic; Dose-Response Relationship, Radiation; Ficusin; Humans; M | 1995 |
Antiproliferative activity and phototoxicity of some methyl derivatives of 5-methoxypsoralen and 5-methoxyangelicin.
Topics: 5-Methoxypsoralen; Animals; Antineoplastic Agents; Cell Division; Dermatitis, Phototoxic; Dose-Respo | 1998 |
Phototoxic contact dermatitis from 5-methoxypsoralen in aromatherapy oil.
Topics: 5-Methoxypsoralen; Aromatherapy; Baths; Child; Dermatitis, Phototoxic; Female; Humans; Methoxsalen | 1998 |
Development of a highly sensitive in vitro phototoxicity assay using the SkinEthic reconstructed human epidermis.
Topics: 4-Aminobenzoic Acid; 5-Methoxypsoralen; Adult; Antipruritics; Benzophenones; Chlorpromazine; Colorin | 2000 |