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5-methoxypsoralen and Dermatitis, Contact, Phototoxic

5-methoxypsoralen has been researched along with Dermatitis, Contact, Phototoxic in 10 studies

5-Methoxypsoralen: A linear furanocoumarin that has phototoxic and anti-inflammatory properties, with effects similar to METHOXSALEN. It is used in PUVA THERAPY for the treatment of PSORIASIS.
5-methoxypsoralen : A 5-methoxyfurocoumarin that is psoralen substituted by a methoxy group at position 5.

Research Excerpts

ExcerptRelevanceReference
"A patient developed severe bullous phototoxic contact dermatitis caused by Ruta graveolens L."2.40[Bullous phototoxic contact dermatitis caused by Ruta graveolens L. (garden rue), Rutaceae. Case report and review of literature]. ( Schempp, CM; Schöpf, E; Simon, JC, 1999)
" Seventy-two hours after UVA exposure minimal phototoxic doses (MPD) were defined visually and the intensity of the erythema response was also assessed by using a narrowband spectrophotometer The MPD and the dose-response curves for erythema response of the gels and creams were compared with those of the bath."1.33Phototoxicity of new psoralen-containing gels and creams versus bath PUVA. ( Leenutaphong, V; Nimkulrat, P; Sudtim, S, 2005)
"In such conditions, the phototoxicity assay is much more sensitive, so that the model is expected to be of great interest for the detection not only of strong but also of weak phototoxic compounds."1.31Development of a highly sensitive in vitro phototoxicity assay using the SkinEthic reconstructed human epidermis. ( Barrault, C; Bernard, FX; De Wever, B; Deguercy, A; Rosdy, M, 2000)
"Histopathology revealed skin phototoxicity of compounds which lacked erythemogenic activity by visual scoring."1.30Antiproliferative activity and phototoxicity of some methyl derivatives of 5-methoxypsoralen and 5-methoxyangelicin. ( Conconi, MT; Montesi, F; Parnigotto, PP, 1998)
"The photogenotoxicity of this suction blister fluid containing 5-methoxypsoralen and also other ingredients of the tanning preparation was assayed on yeast cells and was found to be rather low."1.29Evaluation of phototoxic and photogenotoxic risk associated with the use of photosensitizers in suntan preparations: application to tanning preparations containing bergamot oil. ( Averbeck, D; Dubertret, L; Morlière, P; Moysan, A, 1993)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (60.00)18.2507
2000's3 (30.00)29.6817
2010's1 (10.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Maciel, B1
Moreira, P1
Carmo, H1
Gonçalo, M1
Lobo, JMS1
Almeida, IF1
Marrot, L1
Labarussiat, A1
Perez, P1
Meunier, JR1
Nimkulrat, P1
Leenutaphong, V1
Sudtim, S1
Yasui, Y1
Hirone, T1
Moysan, A1
Morlière, P1
Averbeck, D1
Dubertret, L1
Knudsen, EA1
Bech-Thomsen, N1
Wulf, HC1
Conconi, MT1
Montesi, F1
Parnigotto, PP1
Clark, SM1
Wilkinson, SM1
Schempp, CM1
Schöpf, E1
Simon, JC1
Bernard, FX1
Barrault, C1
Deguercy, A1
De Wever, B1
Rosdy, M1

Reviews

1 review available for 5-methoxypsoralen and Dermatitis, Contact, Phototoxic

ArticleYear
[Bullous phototoxic contact dermatitis caused by Ruta graveolens L. (garden rue), Rutaceae. Case report and review of literature].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1999, Volume: 50, Issue:6

    Topics: 5-Methoxypsoralen; Alkaloids; Anti-Infective Agents, Local; Carcinogens; Cross-Linking Reagents; Der

1999

Other Studies

9 other studies available for 5-methoxypsoralen and Dermatitis, Contact, Phototoxic

ArticleYear
Implementation of an in vitro methodology for phototoxicity evaluation in a human keratinocyte cell line.
    Toxicology in vitro : an international journal published in association with BIBRA, 2019, Volume: 61

    Topics: 5-Methoxypsoralen; Animal Testing Alternatives; Animals; Aspirin; Biological Assay; Cell Line; Chlor

2019
Use of the yeast Saccharomyces cerevisiae as a pre-screening approach for assessment of chemical-induced phototoxicity.
    Toxicology in vitro : an international journal published in association with BIBRA, 2006, Volume: 20, Issue:6

    Topics: 5-Methoxypsoralen; Dermatitis, Phototoxic; Drug Evaluation, Preclinical; Methoxsalen; Saccharomyces

2006
Phototoxicity of new psoralen-containing gels and creams versus bath PUVA.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2005, Volume: 88, Issue:10

    Topics: 5-Methoxypsoralen; Administration, Topical; Adolescent; Adult; Aged; Baths; Dermatitis, Phototoxic;

2005
Action spectrum for bergamot-oil phototoxicity measured by sunburn cell counting.
    The Journal of dermatology, 1994, Volume: 21, Issue:5

    Topics: 5-Methoxypsoralen; Animals; Cell Count; Dermatitis, Phototoxic; Dose-Response Relationship, Radiatio

1994
Evaluation of phototoxic and photogenotoxic risk associated with the use of photosensitizers in suntan preparations: application to tanning preparations containing bergamot oil.
    Skin pharmacology : the official journal of the Skin Pharmacology Society, 1993, Volume: 6, Issue:4

    Topics: 5-Methoxypsoralen; Blister; Dermatitis, Phototoxic; Gas Chromatography-Mass Spectrometry; Humans; Me

1993
Ultraviolet A-induced photodegradation of 5-methoxypsoralen, 8-methoxypsoralen and psoralen reduces the biological effectiveness of the furocoumarins in vivo.
    Photodermatology, photoimmunology & photomedicine, 1995, Volume: 11, Issue:3

    Topics: 5-Methoxypsoralen; Dermatitis, Phototoxic; Dose-Response Relationship, Radiation; Ficusin; Humans; M

1995
Antiproliferative activity and phototoxicity of some methyl derivatives of 5-methoxypsoralen and 5-methoxyangelicin.
    Pharmacology & toxicology, 1998, Volume: 82, Issue:4

    Topics: 5-Methoxypsoralen; Animals; Antineoplastic Agents; Cell Division; Dermatitis, Phototoxic; Dose-Respo

1998
Phototoxic contact dermatitis from 5-methoxypsoralen in aromatherapy oil.
    Contact dermatitis, 1998, Volume: 38, Issue:5

    Topics: 5-Methoxypsoralen; Aromatherapy; Baths; Child; Dermatitis, Phototoxic; Female; Humans; Methoxsalen

1998
Development of a highly sensitive in vitro phototoxicity assay using the SkinEthic reconstructed human epidermis.
    Cell biology and toxicology, 2000, Volume: 16, Issue:6

    Topics: 4-Aminobenzoic Acid; 5-Methoxypsoralen; Adult; Antipruritics; Benzophenones; Chlorpromazine; Colorin

2000