5-methoxypsoralen has been researched along with Actinic Reticuloid Syndrome in 25 studies
5-Methoxypsoralen: A linear furanocoumarin that has phototoxic and anti-inflammatory properties, with effects similar to METHOXSALEN. It is used in PUVA THERAPY for the treatment of PSORIASIS.
5-methoxypsoralen : A 5-methoxyfurocoumarin that is psoralen substituted by a methoxy group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| " With a new liquid preparation of 5-MOP we have now extended our earlier investigation on a larger clinical scale and have correlated the clinical response with the bioavailability of the drug." | 6.66 | 5-Methoxypsoralen (Bergapten) for photochemotherapy. Bioavailability, phototoxicity, and clinical efficacy in psoriasis of a new drug preparation. ( Hönigsmann, H; Ortel, B; Rappersberger, K; Tanew, A, 1988) |
| "Pimpinellin was recently found to be phototoxic, but an action spectrum of sphondin is reported for the first time." | 5.27 | Phototoxicity from furocoumarins (psoralens) of Heracleum laciniatum in a patient with vitiligo. Action spectrum studies on bergapten, pimpinellin, angelicin and sphondin. ( Kavli, G; Midelfart, K; Raa, J; Volden, G, 1983) |
| " With a new liquid preparation of 5-MOP we have now extended our earlier investigation on a larger clinical scale and have correlated the clinical response with the bioavailability of the drug." | 2.66 | 5-Methoxypsoralen (Bergapten) for photochemotherapy. Bioavailability, phototoxicity, and clinical efficacy in psoriasis of a new drug preparation. ( Hönigsmann, H; Ortel, B; Rappersberger, K; Tanew, A, 1988) |
| "Three phototherapeutic regimens with photosensitization are now used in dermatology: PUVA (psoralen + UVA), TUV (crude coaltar + UV), PRT (phototherapy with hematoporphyrin derivative)." | 2.37 | [Problems posed by the therapeutic use of photosensitizers in dermatology]. ( Amblard, P; Beani, JC; Reymond, JL, 1986) |
| " Experiments on suction blister fluids taken from patients after topical treatment with BO containing 5-MOP indicate that in comparison with water the bioavailability and thus the genotoxic effects of the compounds are decreased." | 1.28 | Genotoxicity of bergapten and bergamot oil in Saccharomyces cerevisiae. ( Averbeck, D; Averbeck, S; Dubertret, L; Morlière, P; Young, AR, 1990) |
| "Pimpinellin was recently found to be phototoxic, but an action spectrum of sphondin is reported for the first time." | 1.27 | Phototoxicity from furocoumarins (psoralens) of Heracleum laciniatum in a patient with vitiligo. Action spectrum studies on bergapten, pimpinellin, angelicin and sphondin. ( Kavli, G; Midelfart, K; Raa, J; Volden, G, 1983) |
| "Ingestion of the fruit does not cause photosensitization and the absence of photoactive furocoumarins in the fruit and its sap remains unexplained." | 1.27 | Ficus carica; isolation and quantification of the photoactive components. ( Abi Ali, L; Aftimos, BG; Khalidi, U; Kurban, AK; Tenekjian, KK; Zaynoun, ST, 1984) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (60.00) | 18.7374 |
| 1990's | 7 (28.00) | 18.2507 |
| 2000's | 2 (8.00) | 29.6817 |
| 2010's | 1 (4.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chee, SN | 1 |
| Novakovic, L | 1 |
| Fassihi, H | 1 |
| Garibaldinos, T | 1 |
| Sarkany, R | 1 |
| Wolff, K | 1 |
| Hönigsmann, H | 2 |
| Kavli, G | 3 |
| Raa, J | 2 |
| Johnson, BE | 1 |
| Volden, G | 3 |
| Haugsbø, S | 1 |
| Midelfart, K | 2 |
| Zaynoun, ST | 2 |
| Aftimos, BG | 1 |
| Abi Ali, L | 2 |
| Tenekjian, KK | 2 |
| Khalidi, U | 1 |
| Kurban, AK | 2 |
| Pathak, MA | 1 |
| Krokan, H | 1 |
| Walter, JF | 1 |
| Gange, RW | 1 |
| Mendelson, IR | 1 |
| Kornhauser, A | 1 |
| Wamer, WG | 1 |
| Giles, AL | 1 |
| Aftimos, BA | 1 |
| Piérard, GE | 1 |
| Piérard-Franchimont, C | 1 |
| Nikkels, AF | 1 |
| Arrese, JE | 1 |
| Wolf, P | 2 |
| Müllegger, R | 1 |
| Cerroni, L | 1 |
| Aigner, R | 1 |
| Fueger, G | 1 |
| Höfler, G | 1 |
| Derbaschnig, J | 1 |
| Kerl, H | 1 |
| Chandler, R | 1 |
| Diawara, MM | 1 |
| Caprioglio, H | 1 |
| Chavez, KJ | 1 |
| Williams, DE | 1 |
| Sauter, C | 1 |
| Legat, FJ | 1 |
| Kränke, B | 1 |
| Schlatter, J | 1 |
| Zimmerli, B | 1 |
| Dick, R | 1 |
| Panizzon, R | 1 |
| Schlatter, C | 1 |
| Ena, P | 1 |
| Cerri, R | 1 |
| Dessi, G | 1 |
| Manconi, PM | 1 |
| Atzei, AD | 1 |
| Averbeck, D | 1 |
| Averbeck, S | 1 |
| Dubertret, L | 1 |
| Young, AR | 1 |
| Morlière, P | 1 |
| Baran, R | 1 |
| Barthélémy, H | 1 |
| Pira, E | 1 |
| Romano, C | 1 |
| Sulotto, F | 1 |
| Pavan, I | 1 |
| Monaco, E | 1 |
| Beani, JC | 1 |
| Amblard, P | 1 |
| Reymond, JL | 1 |
| Tanew, A | 1 |
| Ortel, B | 1 |
| Rappersberger, K | 1 |
| Tamaro, M | 1 |
| Gastaldi, S | 1 |
| Carlassare, F | 1 |
| Babudri, N | 1 |
| Pani, B | 1 |
| Zaynoun, S | 1 |
| Tenekjian, K | 1 |
| Kurban, A | 1 |
| Naganuma, M | 1 |
| Hirose, S | 1 |
| Nakayama, Y | 1 |
| Nakajima, K | 1 |
| Someya, T | 1 |
2 reviews available for 5-methoxypsoralen and Actinic Reticuloid Syndrome
| Article | Year |
|---|---|
Sunscreens: topical and systemic approaches for protection of human skin against harmful effects of solar radiation.
Topics: 5-Methoxypsoralen; Administration, Oral; Administration, Topical; beta Carotene; Carotenoids; Chloro | 1982 |
[Problems posed by the therapeutic use of photosensitizers in dermatology].
Topics: 5-Methoxypsoralen; Coal Tar; DNA; Furocoumarins; Hematoporphyrin Derivative; Hematoporphyrin Photora | 1986 |
1 trial available for 5-methoxypsoralen and Actinic Reticuloid Syndrome
| Article | Year |
|---|---|
5-Methoxypsoralen (Bergapten) for photochemotherapy. Bioavailability, phototoxicity, and clinical efficacy in psoriasis of a new drug preparation.
Topics: 5-Methoxypsoralen; Biological Availability; Clinical Trials as Topic; Drug Administration Schedule; | 1988 |
22 other studies available for 5-methoxypsoralen and Actinic Reticuloid Syndrome
| Article | Year |
|---|---|
Chronic actinic dermatitis: successful treatment with psoralen-ultraviolet A photochemotherapy.
Topics: 5-Methoxypsoralen; Adult; Drug Administration Schedule; Female; Humans; Male; Methoxsalen; Photosens | 2018 |
Safety and therapeutic effectiveness of selected psoralens in psoriasis.
Topics: 5-Methoxypsoralen; DNA; Furocoumarins; Humans; Methoxsalen; Photochemotherapy; Photosensitivity Diso | 1984 |
Furocoumarins of Heracleum laciniatum: isolation, phototoxicity, absorption and action spectra studies.
Topics: 5-Methoxypsoralen; Furocoumarins; Humans; Methoxsalen; Photosensitivity Disorders; Plants; Skin Test | 1983 |
Phototoxicity from furocoumarins (psoralens) of Heracleum laciniatum in a patient with vitiligo. Action spectrum studies on bergapten, pimpinellin, angelicin and sphondin.
Topics: 5-Methoxypsoralen; Adult; Anticonvulsants; Female; Furocoumarins; Humans; Intercalating Agents; Isom | 1983 |
Ficus carica; isolation and quantification of the photoactive components.
Topics: 5-Methoxypsoralen; Fruit; Furocoumarins; Humans; Methoxsalen; Photosensitivity Disorders | 1984 |
Photochemical reactions of Heracleum laciniatum. Influence of dimethyl sulphoxide and corticosteroids.
Topics: 5-Methoxypsoralen; Desoximetasone; Dexamethasone; Dimethyl Sulfoxide; Furocoumarins; Humans; Methoxs | 1983 |
Psoralen-containing sunscreen induces phototoxicity and epidermal ornithine decarboxylase activity.
Topics: 5-Methoxypsoralen; Animals; Carboxy-Lyases; Enzyme Induction; Epidermis; Female; Humans; Methoxsalen | 1982 |
Psoralen phototoxicity: correlation with serum and epidermal 8-methoxypsoralen and 5-methoxypsoralen in the guinea pig.
Topics: 5-Methoxypsoralen; Administration, Oral; Administration, Topical; Animals; Epidermis; Guinea Pigs; M | 1982 |
Berloque dermatitis - a continuing cosmetic problem.
Topics: 5-Methoxypsoralen; Adult; Female; Humans; Infant; Male; Methoxsalen; Perfume; Photosensitivity Disor | 1981 |
Acquired persistent atypical lentigines as a failure of 5-methoxypsoralen-containing sunscreens in the photochemoprotection from ultraviolet-radiation-induced damage.
Topics: 5-Methoxypsoralen; Adult; Female; Humans; Lentigo; Methoxsalen; Photosensitivity Disorders; Radiatio | 1995 |
Photoaccentuated erythroderma associated with CD4+ T lymphocytopenia: successful treatment with 5-methoxypsoralen and UVA, interferon alfa-2b, and extracorporeal photopheresis.
Topics: 5-Methoxypsoralen; Dermatitis, Exfoliative; HIV Seronegativity; Humans; Interferon alpha-2; Interfer | 1996 |
Examination of psoralens-induced photodermatitis in Wistar rats under scanning electron microscopy.
Topics: 5-Methoxypsoralen; Animals; Dose-Response Relationship, Drug; Drug Synergism; Female; Hair; Methoxsa | 1999 |
[Heracl'eum mantegazzi'anum: photosensitization].
Topics: 5-Methoxypsoralen; Breast Neoplasms; Dermatitis, Contact; Diagnosis, Differential; Female; Humans; M | 2001 |
Anaphylaxis to 5-methoxypsoralen during photochemotherapy.
Topics: 5-Methoxypsoralen; Adult; Anaphylaxis; Drug Eruptions; Female; Humans; Methoxsalen; Photosensitivity | 2001 |
Dietary intake and risk assessment of phototoxic furocoumarins in humans.
Topics: 5-Methoxypsoralen; Administration, Oral; Chromatography, High Pressure Liquid; Furocoumarins; Humans | 1991 |
Phototoxicity due to Cachrys libanotis.
Topics: 5-Methoxypsoralen; Adult; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Fruit; F | 1991 |
Genotoxicity of bergapten and bergamot oil in Saccharomyces cerevisiae.
Topics: 5-Methoxypsoralen; Diploidy; Genes, Fungal; Haploidy; Humans; Light; Methoxsalen; Mutagens; Oxygen; | 1990 |
[Photo-onycholysis caused by 5-MOP (Psoraderm) and the application of the imputation method of drug effects].
Topics: 5-Methoxypsoralen; Adult; Female; Humans; Methoxsalen; Nail Diseases; Photosensitivity Disorders | 1990 |
Heracleum mantegazzianum growth phases and furocoumarin content.
Topics: 5-Methoxypsoralen; Botany; Dermatitis, Occupational; Fruit; Furocoumarins; Humans; Isomerism; Methox | 1989 |
Genotoxic activity of some water-soluble derivatives of 5-methoxypsoralen and 8-methoxypsoralen.
Topics: 5-Methoxypsoralen; Animals; Cell Division; Cell Line; Cricetinae; Cricetulus; Methoxsalen; Mutagenic | 1986 |
The bergapten content of garden parsley and its significance in causing cutaneous photosensitization.
Topics: 5-Methoxypsoralen; Food; Hand Dermatoses; Humans; Magnoliopsida; Methoxsalen; Photosensitivity Disor | 1985 |
A study of the phototoxicity of lemon oil.
Topics: 5-Methoxypsoralen; Animals; Citrus; Coumarins; Furocoumarins; Guinea Pigs; Methoxsalen; Oils, Volati | 1985 |