5-hydroxytryptophan has been researched along with Vomiting in 7 studies
5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.
Vomiting: The forcible expulsion of the contents of the STOMACH through the MOUTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A recently developed oral serotonergic challenge test consisting of 5-Hydroxytryptophane (5-HTP, 200 mg) combined with carbidopa (CBD, 100 mg + 50 mg) exhibited dose-related neuroendocrine responsiveness and predictable pharmacokinetics." | 2.75 | Enhanced tolerability of the 5-hydroxytryptophane challenge test combined with granisetron. ( de Kam, ML; Derijk, RH; Jacobs, GE; Kamerling, IM; van Gerven, JM; van Pelt, J; Zitman, FG, 2010) |
| "5-hydroxytryptophan (5-HTP) is a direct 5-hydroxytryptamine (5-HT) precursor used to assess central serotonergic function." | 2.73 | Pharmacology of rising oral doses of 5-hydroxytryptophan with carbidopa. ( de Kam, ML; de Rijk, R; Gijsman, HJ; Hoeberechts-Lefrandt, DH; Jacobs, GE; Schoemaker, RC; Smarius, LJ; van der Post, JP; van Gerven, JM; van Pelt, J; Zitman, FG, 2008) |
| " By combining 5-HTP with carbidopa (CBD), increased bioavailability for brain penetration and decreased peripheral side effects would be expected, due to reduced peripheral decarboxylation of 5-HTP to 5-HT." | 2.73 | Pharmacology of rising oral doses of 5-hydroxytryptophan with carbidopa. ( de Kam, ML; de Rijk, R; Gijsman, HJ; Hoeberechts-Lefrandt, DH; Jacobs, GE; Schoemaker, RC; Smarius, LJ; van der Post, JP; van Gerven, JM; van Pelt, J; Zitman, FG, 2008) |
| " A double-blind, placebo-controlled, single rising dose, four-way crossover trial with placebo randomisation was performed in 15 healthy male volunteers to investigate the neuroendocrine dose-response relationship at various 5-HTP levels; the tolerability and subjective effects of oral 5-HTP at 100, 200 and 300 mg combined with CBD and the pharmacokinetic properties of the 5-HTP/CBD-challenge." | 2.73 | Pharmacology of rising oral doses of 5-hydroxytryptophan with carbidopa. ( de Kam, ML; de Rijk, R; Gijsman, HJ; Hoeberechts-Lefrandt, DH; Jacobs, GE; Schoemaker, RC; Smarius, LJ; van der Post, JP; van Gerven, JM; van Pelt, J; Zitman, FG, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (28.57) | 18.7374 |
| 1990's | 2 (28.57) | 18.2507 |
| 2000's | 1 (14.29) | 29.6817 |
| 2010's | 2 (28.57) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Haruki, H | 1 |
| Pedersen, MG | 1 |
| Gorska, KI | 1 |
| Pojer, F | 1 |
| Johnsson, K | 1 |
| Jacobs, GE | 2 |
| Kamerling, IM | 1 |
| de Kam, ML | 2 |
| Derijk, RH | 1 |
| van Pelt, J | 2 |
| Zitman, FG | 2 |
| van Gerven, JM | 2 |
| Smarius, LJ | 1 |
| Hoeberechts-Lefrandt, DH | 1 |
| van der Post, JP | 1 |
| de Rijk, R | 1 |
| Schoemaker, RC | 1 |
| Gijsman, HJ | 1 |
| Matsui, K | 1 |
| Fukuoka, M | 1 |
| Takada, M | 1 |
| Kusunoki, Y | 1 |
| Yana, T | 1 |
| Tamura, K | 1 |
| Yoshida, T | 1 |
| Iida, K | 1 |
| Hirashima, T | 1 |
| Tsukada, H | 1 |
| Ushijima, S | 1 |
| Miyawaki, H | 1 |
| Masuda, N | 1 |
| Rudd, JA | 1 |
| Cheng, CH | 1 |
| Naylor, RJ | 1 |
| Ursin, R | 1 |
| Sano, I | 1 |
3 trials available for 5-hydroxytryptophan and Vomiting
| Article | Year |
|---|---|
Enhanced tolerability of the 5-hydroxytryptophane challenge test combined with granisetron.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Antidepressive Agents, Second-Generation; Antiemetics; Area | 2010 |
Pharmacology of rising oral doses of 5-hydroxytryptophan with carbidopa.
Topics: 5-Hydroxytryptophan; Administration, Oral; Adrenocorticotropic Hormone; Adult; Affect; Antidepressiv | 2008 |
Randomised trial for the prevention of delayed emesis in patients receiving high-dose cisplatin.
Topics: 5-Hydroxytryptophan; Administration, Oral; Adult; Aged; Antiemetics; Antineoplastic Agents; Carcinom | 1996 |
4 other studies available for 5-hydroxytryptophan and Vomiting
| Article | Year |
|---|---|
Tetrahydrobiopterin biosynthesis as an off-target of sulfa drugs.
Topics: 5-Hydroxytryptophan; Adult; Alcohol Oxidoreductases; Anti-Infective Agents; Biopterins; Cell Line; C | 2013 |
Serotonin-independent model of cisplatin-induced emesis in the ferret.
Topics: 5-Hydroxytryptophan; Animals; Brain; Cisplatin; Cross-Linking Reagents; Dopamine; Epinephrine; Fencl | 1998 |
The effects of 5-hydroxytryptophan and L-tryptophan on wakefulness and sleep patterns in the cat.
Topics: 5-Hydroxytryptophan; Animals; Brain; Cats; Electroencephalography; Electromyography; Female; Male; M | 1976 |
[L-5-hydroxytryptophan(L-5-HTP) therapy in endogenous depression. 1].
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Benzoates; Bipolar Disorder; Child; Depression; Female | 1972 |