Page last updated: 2024-10-16

5-hydroxytryptophan and Tension-Type Headache

5-hydroxytryptophan has been researched along with Tension-Type Headache in 2 studies

5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.

Tension-Type Headache: A common primary headache disorder, characterized by a dull, non-pulsatile, diffuse, band-like (or vice-like) PAIN of mild to moderate intensity in the HEAD; SCALP; or NECK. The subtypes are classified by frequency and severity of symptoms. There is no clear cause even though it has been associated with MUSCLE CONTRACTION and stress. (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)

Research Excerpts

ExcerptRelevanceReference
"A parallel, randomized, double-blind trial is reported, in which 78 patients with chronic tension-type headaches were treated with L-5-hydroxytryptophan (5-HTP) (n = 43) or placebo (n = 35) for 8 weeks, after a washout period of 2 weeks and with a follow-up period of a further 2 weeks."9.09L-5-Hydroxytryptophan in the prophylaxis of chronic tension-type headache: a double-blind, randomized, placebo-controlled study. For the Portuguese Head Society. ( Ribeiro, CA, 2000)
"Interictal serum levels of serotonin and plasma and mononuclear cell concentrations of beta-endorphin were measured in 20 juvenile patients (13 suffering from migraine without aura and 7 from episodic tension-type headache) before and after 3 months of L-5-hydroxytryptophan treatment (5 mg/kg/day) and compared with a control group of 17 headache-free healthy subjects."9.08beta-endorphin in plasma and monocytes in juvenile headache. ( Battistella, PA; Bordin, A; Broetto, S; Cernetti, R; Corrà, S; Piva, E; Plebani, M, 1996)
"A parallel, randomized, double-blind trial is reported, in which 78 patients with chronic tension-type headaches were treated with L-5-hydroxytryptophan (5-HTP) (n = 43) or placebo (n = 35) for 8 weeks, after a washout period of 2 weeks and with a follow-up period of a further 2 weeks."5.09L-5-Hydroxytryptophan in the prophylaxis of chronic tension-type headache: a double-blind, randomized, placebo-controlled study. For the Portuguese Head Society. ( Ribeiro, CA, 2000)
"Interictal serum levels of serotonin and plasma and mononuclear cell concentrations of beta-endorphin were measured in 20 juvenile patients (13 suffering from migraine without aura and 7 from episodic tension-type headache) before and after 3 months of L-5-hydroxytryptophan treatment (5 mg/kg/day) and compared with a control group of 17 headache-free healthy subjects."5.08beta-endorphin in plasma and monocytes in juvenile headache. ( Battistella, PA; Bordin, A; Broetto, S; Cernetti, R; Corrà, S; Piva, E; Plebani, M, 1996)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (50.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Battistella, PA1
Bordin, A1
Cernetti, R1
Broetto, S1
Corrà, S1
Piva, E1
Plebani, M1
Ribeiro, CA1

Trials

2 trials available for 5-hydroxytryptophan and Tension-Type Headache

ArticleYear
beta-endorphin in plasma and monocytes in juvenile headache.
    Headache, 1996, Volume: 36, Issue:2

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; beta-Endorphin; Child; Female; Headache; Humans; Male; Migra

1996
L-5-Hydroxytryptophan in the prophylaxis of chronic tension-type headache: a double-blind, randomized, placebo-controlled study. For the Portuguese Head Society.
    Headache, 2000, Volume: 40, Issue:6

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Chronic Disease; Double-Blind Method; Female; Humans; Incide

2000