Page last updated: 2024-10-16

5-hydroxytryptophan and Schizophrenia

5-hydroxytryptophan has been researched along with Schizophrenia in 32 studies

5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.

Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199028 (87.50)18.7374
1990's1 (3.13)18.2507
2000's1 (3.13)29.6817
2010's2 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fukuda, K2
BRENGELMANN, JC1
PARE, CM1
SANDLER, M1
FELDSTEIN, A1
FREEMAN, H1
HOPE, JM1
DIBNER, IM1
HOAGLAND, H1
TAUTZ, NA1
BENTE, D1
SCHMID, E1
SCHMID-CLAUDY, E1
KLEE, GD1
BERTINO, J1
GOODMAN, A1
ARONSON, H1
Tekes, K1
Young, SN1
Gauthier, S1
Chouinard, G1
Anderson, GM1
Purdy, WC1
Thompson, PA1
Maes, M1
Meltzer, HY1
Carlsson, A1
Nakajima, T1
Kudo, Y1
Kaneko, Z1
Borison, RL1
Havdala, HS1
Diamond, BI1
Bigelow, LB1
Walls, P1
Gillin, JC1
Wyatt, RJ3
Tissot, R2
Albert, TJ1
Dempesy, CW1
Sorenson, CA1
Irwin, M1
Fuentenebro, F1
Marder, SR1
Yuwiler, A1
Hoshino, Y1
Kaneko, M1
Kumashiro, H1
Tachibana, R1
Frohman, CE2
Harmison, CR1
Arthur, RE2
Gottlieb, JS1
Cowen, MA1
Koella, WP1
Lipton, MA1
Warner, KA1
Barry, CT1
Laborit, H1
Williams, RH1
Vaughan, T2
Galanter, M1
Kaplan, J2
Green, R1
Airaksinen, MM1
McIsaac, WM1
Maire, FW1
Hixon, AC1
Persson, T1
Roos, BE1
Tanimukai, H1
Ginther, R1
Spaide, J1
Bueno, JR1
Himwich, HE1

Reviews

5 reviews available for 5-hydroxytryptophan and Schizophrenia

ArticleYear
The common pathophysiology of monaminergic psychoses: a new hypothesis.
    Neuropsychobiology, 1975, Volume: 1, Issue:4

    Topics: 5-Hydroxytryptophan; Amino Acids; Biological Transport, Active; Bipolar Disorder; Blood-Brain Barrie

1975
What is the functional role of central nervous serotonin?
    Neurosciences research, 1969, Volume: 2, Issue:0

    Topics: 5-Hydroxytryptophan; Animals; Body Temperature Regulation; Brain; Cats; Central Nervous System; Circ

1969
[Molecular organicity of abnormal behaviors and mental disorders].
    Agressologie: revue internationale de physio-biologie et de pharmacologie appliquees aux effets de l'agression, 1972, Volume: 13, Issue:2

    Topics: 5-Hydroxytryptophan; Catecholamines; Humans; Mental Disorders; Phenethylamines; Psychosexual Develop

1972
Indolealkylamines and behavior.
    Annales medicinae experimentalis et biologiae Fenniae, 1968, Volume: 46, Issue:3

    Topics: 5-Hydroxytryptophan; Alkaloids; Amines; Animals; Behavior; Brain; Brain Chemistry; Cats; Chemical Ph

1968
Biogenic amines and psychiatry.
    The Australian and New Zealand journal of psychiatry, 1971, Volume: 5, Issue:1

    Topics: 5-Hydroxytryptophan; Affective Symptoms; Amines; Amphetamine; Anxiety Disorders; Attention Deficit D

1971

Trials

4 trials available for 5-hydroxytryptophan and Schizophrenia

ArticleYear
Effect of the placebo control condition in neuroendocrine challenge studies.
    Psychiatry research, 1994, Volume: 52, Issue:3

    Topics: 5-Hydroxytryptophan; Antipsychotic Agents; Apomorphine; Bias; Buspirone; Data Interpretation, Statis

1994
Clinical effects of L-5-hydroxytryptophan administration in chronic schizophrenic patients.
    Biological psychiatry, 1979, Volume: 14, Issue:1

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Carbidopa; Chlorpromazine; Chronic Disease; Clinical Trials

1979
Behavioral changes of chronic schizophrenic patients given L-5-hydroxytryptophan.
    Science (New York, N.Y.), 1972, Sep-22, Volume: 177, Issue:4054

    Topics: 5-Hydroxytryptophan; Administration, Oral; Adult; Brain; Carboxy-Lyases; Clinical Trials as Topic; H

1972
Tolerance and dependence to serotonin. A speculation.
    Archives of general psychiatry, 1973, Volume: 29, Issue:5

    Topics: 5-Hydroxytryptophan; Adult; Animals; Brain Chemistry; Cats; Chronic Disease; Clinical Trials as Topi

1973

Other Studies

23 other studies available for 5-hydroxytryptophan and Schizophrenia

ArticleYear
5-HTP hypothesis of schizophrenia.
    Medical hypotheses, 2014, Volume: 82, Issue:1

    Topics: 5-Hydroxytryptophan; Brain; Feedback, Physiological; Humans; Models, Biological; Schizophrenia; Sero

2014
Integrated theory to unify status among schizophrenia and manic depressive illness.
    Medical hypotheses, 2015, Volume: 85, Issue:4

    Topics: 5-Hydroxytryptophan; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Biopterins; Bipolar Dis

2015
Effects of 5-hydroxytryptophan on schizophrenia.
    The Journal of mental science, 1959, Volume: 105

    Topics: 5-Hydroxytryptophan; Brain; Humans; Neurochemistry; Schizophrenia; Serotonin; Tryptophan

1959
The administration of BAS, 5-HTP, and marsilid to schizophrenic patients.
    The American journal of psychiatry, 1959, Volume: 116

    Topics: 5-Hydroxytryptophan; Humans; Isoniazid; Schizophrenia; Serotonin; Tryptophan

1959
[ON SEROTONIN METABOLISM IN ENDOGENOUS PSYCHOSES. I. CLINICAL EXPERIMENTAL STUDIES OF THE CONVERSION OF 5-HTP].
    Medicina experimentalis : International journal of experimental medicine, 1963, Volume: 9

    Topics: 5-Hydroxytryptophan; Biomedical Research; Humans; Mental Disorders; Metabolism; Psychotic Disorders;

1963
The effects of 5-hydroxytryptophan (a serotonin precursor) in schizophrenic patients.
    The Journal of mental science, 1960, Volume: 106

    Topics: 5-Hydroxytryptophan; Schizophrenia; Serotonin; Tryptophan

1960
HPLC determination of serotonin and its metabolites from human platelet-rich plasma; shift to 5-hydroxytryptophol formation following alcohol consumption.
    Journal of chromatographic science, 2008, Volume: 46, Issue:2

    Topics: 5-Hydroxytryptophan; Adult; Alcohol Drinking; Chromatography, High Pressure Liquid; Female; Humans;

2008
The effect of carbidopa and benserazide on human plasma 5-hydroxytryptophan levels.
    Journal of neural transmission, 1982, Volume: 53, Issue:1

    Topics: 5-Hydroxytryptophan; Adult; Benserazide; Carbidopa; Chlorpromazine; Dihydroxyphenylalanine; Humans;

1982
Does dopamine play a role in schizophrenia?
    Psychological medicine, 1977, Volume: 7, Issue:4

    Topics: 5-Hydroxytryptophan; Acetylcholine; Adenylyl Cyclases; Adrenergic alpha-Antagonists; Animals; Brain;

1977
Clinical evaluation of 5-hydroxy-L-tryptophan as an antidepressant drug.
    Folia psychiatrica et neurologica japonica, 1978, Volume: 32, Issue:2

    Topics: 5-Hydroxytryptophan; Adjustment Disorders; Adult; Aged; Antidepressive Agents; Bipolar Disorder; Dru

1978
A new animal model for schizophrenia: cholinergic and serotonergic modulation.
    Communications in psychopharmacology, 1978, Volume: 2, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Dextroamphetamine; Disease Models, Animal; Dose-Resp

1978
[Hypothetical concept: the physiopathological entity of monoaminergic psychoses].
    L'Encephale, 1975, Volume: 1, Issue:4

    Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Behavior, Animal; Bipolar Disorder; Blood-Brain Barrier;

1975
Anterior cerebellar vermal stimulation: effect on behavior and basal forebrain neurochemistry in rat.
    Biological psychiatry, 1985, Volume: 20, Issue:12

    Topics: 5-Hydroxytryptophan; Animals; Brain Mapping; Cerebellum; Dopamine; Electric Stimulation; Humans; Hyd

1985
L-5-Hydroxytryptophan-induced delirium.
    Biological psychiatry, 1986, Volume: 21, Issue:7

    Topics: 5-Hydroxytryptophan; Administration, Oral; Adult; Delirium; Double-Blind Method; Drug Therapy, Combi

1986
Endocrinological function in schizophrenic patients under haloperidol treatment: plasma PRL, HGH and 5HT levels after L-5HTP loading.
    Folia psychiatrica et neurologica japonica, 1985, Volume: 39, Issue:1

    Topics: 5-Hydroxytryptophan; Adult; Growth Hormone; Haloperidol; Humans; Hypothalamic Diseases; Hypothalamo-

1985
Conformation of a unique plasma protein in schizophrenia.
    Biological psychiatry, 1971, Volume: 3, Issue:2

    Topics: 5-Hydroxytryptophan; Adult; Alpha-Globulins; Amino Acids; Animals; Brain; Brain Chemistry; Chemical

1971
Electrophysiological phenomena associated with the S-protein system in normal and schizophrenic subjects.
    Biological psychiatry, 1973, Volume: 7, Issue:2

    Topics: 5-Hydroxytryptophan; Adult; Alpha-Globulins; Animals; Chickens; Electrophysiology; Erythrocytes; Fem

1973
Neuropsychopharmacology of monoamines and their regulatory enzymes.
    Advances in biochemical psychopharmacology, 1974, Volume: 12, Issue:0

    Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Apomorphine; Biogenic Amines; Brain; Cocaine; Dextroamphe

1974
Amino acid transport and the plasma factor in schizophrenia.
    Biological psychiatry, 1969, Volume: 1, Issue:3

    Topics: 5-Hydroxytryptophan; Alpha-Globulins; Amino Acids; Animals; Biological Transport; Carbon Isotopes; C

1969
Metabolism and mentation.
    The Journal of clinical endocrinology and metabolism, 1970, Volume: 31, Issue:5

    Topics: 5-Hydroxytryptophan; Acetylcholine; Amino Acid Metabolism, Inborn Errors; Aminobutyrates; Basal Gang

1970
Behavioral and performance changes in trained rats following bufotenine injection.
    International journal of neuropsychiatry, 1966, Volume: 2, Issue:2

    Topics: 5-Hydroxytryptophan; Alkylation; Animals; Ascorbic Acid; Behavior, Animal; Exploratory Behavior; Hal

1966
Clinical and pharmacological effects of monoamine precursors or haloperidol in chronic schizophrenia.
    Nature, 1968, Mar-02, Volume: 217, Issue:5131

    Topics: 5-Hydroxytryptophan; Dihydroxyphenylalanine; Haloperidol; Humans; Hydroxyindoleacetic Acid; Phenylac

1968
Detection of psychotomimetic N,N-dimethylated indoleamines in the urine of four schizophrenic patients.
    The British journal of psychiatry : the journal of mental science, 1970, Volume: 117, Issue:539

    Topics: 5-Hydroxytryptophan; Adult; Chromatography, Gas; Chromatography, Paper; Chromatography, Thin Layer;

1970