Page last updated: 2024-10-16

5-hydroxytryptophan and Pregnancy

5-hydroxytryptophan has been researched along with Pregnancy in 76 studies

5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"In this study we describe the development and validation of a liquid chromatography mass spectrometry method (LC-MS/MS) to quantify five tryptophan (TRP) metabolites within the kynurenine- and serotonin pathway and apply the method to serum samples of women in the first trimester of pregnancy."8.31Simultaneous quantification of tryptophan metabolites by liquid chromatography tandem mass spectrometry during early human pregnancy. ( de Rijke, YB; Griffioen, PH; Mirzaian, M; Steegers-Theunissen, RPM; van Rossem, L; van Schaik, RHN; van Zundert, SKM; Willemsen, SP, 2023)
"The LC-MS/MS method is able to accurately quantify kynurenine- and serotonin pathway metabolites in pregnant women, providing an opportunity to investigate the role of the TRP metabolism in the (patho)physiology of pregnancy."8.31Simultaneous quantification of tryptophan metabolites by liquid chromatography tandem mass spectrometry during early human pregnancy. ( de Rijke, YB; Griffioen, PH; Mirzaian, M; Steegers-Theunissen, RPM; van Rossem, L; van Schaik, RHN; van Zundert, SKM; Willemsen, SP, 2023)
" We describe two sisters with hemiplegic migraine, low CSF and platelet serotonin levels, and progressive spastic paraparesis associated with profound spinal cord atrophy whose lower extremity strength and ambulation responded to a precursor replacement strategy (5-hydroxytryptophan and carbidopa administration), an approach that may have broader applicability in myelopathies of diverse etiology where descending serotonergic projections are compromised."7.85Improved strength on 5-hydroxytryptophan and carbidopa in spinal cord atrophy. ( Carleton, B; Horvath, GA; Meisner, L; Selby, K; Stowe, R, 2017)
"In this study we describe the development and validation of a liquid chromatography mass spectrometry method (LC-MS/MS) to quantify five tryptophan (TRP) metabolites within the kynurenine- and serotonin pathway and apply the method to serum samples of women in the first trimester of pregnancy."4.31Simultaneous quantification of tryptophan metabolites by liquid chromatography tandem mass spectrometry during early human pregnancy. ( de Rijke, YB; Griffioen, PH; Mirzaian, M; Steegers-Theunissen, RPM; van Rossem, L; van Schaik, RHN; van Zundert, SKM; Willemsen, SP, 2023)
"The LC-MS/MS method is able to accurately quantify kynurenine- and serotonin pathway metabolites in pregnant women, providing an opportunity to investigate the role of the TRP metabolism in the (patho)physiology of pregnancy."4.31Simultaneous quantification of tryptophan metabolites by liquid chromatography tandem mass spectrometry during early human pregnancy. ( de Rijke, YB; Griffioen, PH; Mirzaian, M; Steegers-Theunissen, RPM; van Rossem, L; van Schaik, RHN; van Zundert, SKM; Willemsen, SP, 2023)
"21]) were associated with higher odds of antepartum depression and 4 metabolites (betaine [OR = =0."3.96Metabolomic markers of antepartum depression and suicidal ideation. ( Clish, C; Gelaye, B; Larrabure-Torrealva, GT; Mitro, SD; Molsberry, SA; Sanchez, SE; Williams, MA, 2020)
" We describe two sisters with hemiplegic migraine, low CSF and platelet serotonin levels, and progressive spastic paraparesis associated with profound spinal cord atrophy whose lower extremity strength and ambulation responded to a precursor replacement strategy (5-hydroxytryptophan and carbidopa administration), an approach that may have broader applicability in myelopathies of diverse etiology where descending serotonergic projections are compromised."3.85Improved strength on 5-hydroxytryptophan and carbidopa in spinal cord atrophy. ( Carleton, B; Horvath, GA; Meisner, L; Selby, K; Stowe, R, 2017)
"Pregnant women with preeclampsia have increased serotonin levels, suggesting a possible role of this amine in abnormal pregnancy."1.34Pregnant rats treated with a serotonin precursor have reduced fetal weight and lower plasma volume and kallikrein levels. ( Aranda, E; Downey, P; Giacaman, A; Mezzano, D; Romero, W; Salas, SP; Vío, CP, 2007)
"The most common forms of BH4 deficiency are 6-pyruvoyl-tetrahydropterin synthase (PTPS) deficiency (MIM 261640) and dihydropteridine reductase (DHPR) deficiency (MIM 261630), which require a different treatment from classical HPA."1.31Tetrahydrobiopterin-deficient hyperphenylalaninemia in the Chinese. ( Chiang, SH; Hsiao, KJ; Liu, TT; Wu, SJ, 2001)
" Study results indicate that fetal behavioural states can be altered pharmacologically and in a manner similar to that seen in the adult but with notable differences that may relate to species, developmental or dose-response issues."1.30The effects of 'sleep promoting agents' on behavioural state in the ovine fetus. ( Carmichael, L; Homan, J; Morrison, JL; Richardson, BS, 1997)
"We report a child in whom dihydropteridine reductase deficiency was diagnosed prenatally because of an affected sibling and who was treated from birth with apparent good response."1.28Successful treatment of dihydropteridine reductase deficiency, with an interesting effect of 5-hydroxytryptophan deficiency on sleep patterns. ( Cotton, RG; Earl, JW; Lipson, AH; O'Halloran, M; Wilcken, B; Yu, JS, 1991)
"Reserpine enhanced the incidence of seizures, and the effect was reversed by 5-hydroxytryptophan but not by dihydroxyphenylalanine."1.25Effects of aminergic drugs and glutamic acid on audiogenic seizures induced by early exposure to ethanol. ( Ginsburg, BE; Sze, PY; Yanai, J, 1975)

Research

Studies (76)

TimeframeStudies, this research(%)All Research%
pre-199047 (61.84)18.7374
1990's6 (7.89)18.2507
2000's7 (9.21)29.6817
2010's10 (13.16)24.3611
2020's6 (7.89)2.80

Authors

AuthorsStudies
Zhang, Z1
Du, W2
Liu, W1
Wong, BT1
Zheng, H1
Sarangi, A1
Ghosh, M1
Sangwan, S1
Kumar, R1
Balhara, S1
Phulia, SK1
Sharma, RK1
Sahu, S1
Kumar, S1
Mohanty, AK1
Balhara, AK1
van Zundert, SKM3
Griffioen, PH3
van Rossem, L3
Willemsen, SP3
de Rijke, YB3
van Schaik, RHN3
Steegers-Theunissen, RPM3
Mirzaian, M3
Zhang, ZF1
Xiao, JY1
Wang, Y1
Liu, WY1
Zheng, HL1
Mitro, SD1
Larrabure-Torrealva, GT1
Sanchez, SE1
Molsberry, SA1
Williams, MA1
Clish, C1
Gelaye, B1
Gordeeva, O1
Gordeev, A1
Hernández-Castellano, LE3
Hernandez, LL6
Sauerwein, H1
Bruckmaier, RM4
Horvath, GA1
Meisner, L1
Selby, K1
Stowe, R1
Carleton, B1
Özçelik, R1
Laporta, J3
Peters, TL2
Weaver, SR2
Merriman, KE2
Vezina, CM1
Moore, SA1
Cronick, CM1
Olsen, M1
Prichard, AP1
Schnell, BP1
Crenshaw, TD1
Peñagaricano, F1
Goeden, N1
Velasquez, J1
Arnold, KA1
Chan, Y1
Lund, BT1
Anderson, GM1
Bonnin, A1
Kovács, L1
Kézér, FL1
Ruff, F1
Szenci, O1
Weaver, S1
Blazevic, S1
Colic, L1
Culig, L1
Hranilovic, D1
KIMURA, Y1
ARAI, Y1
OKUNI, H1
Carretti, N1
Bertazzo, A1
Comai, S1
Costa, CV1
Allegri, G1
Petraglia, F1
Freeman, MP1
Helgason, C1
Hill, RA1
Peng, SS1
Tseng, WY1
Chien, YH1
Hwu, WL1
Liu, HM1
Salas, SP1
Giacaman, A1
Romero, W1
Downey, P1
Aranda, E1
Mezzano, D1
Vío, CP1
Walker, RF1
Johnston, CA1
Demarest, KT1
Moore, KE1
Savchenko, ON2
Podsedlovski, RT1
Strel'tsova, NA1
Danilova, OA2
Coen, CW2
Franklin, M1
Laynes, RW1
MacKinnon, PC2
Propp, MV1
Stepanov, GS1
Maslova, LN1
Marti-Henneberg, C1
Gluckman, PD1
Kaplan, SL1
Grumbach, MM1
Quilligan, EJ1
Clewlow, F1
Johnston, BM1
Walker, DW1
Grandison, L1
London, ED1
Waller, SB1
Vocci, FJ1
Buterbaugh, GG1
Hedner, T2
Lundborg, P3
Cecim, M1
Fadden, C1
Kerr, J1
Steger, RW1
Bartke, A1
Paolillo, M1
Preda, S1
Corona, GL1
Schinelli, S1
Morrison, JL1
Carmichael, L1
Homan, J1
Richardson, BS1
Jahn, GA2
Kalia, V1
Hole, D1
Wilson, CA1
Deis, RP2
Liu, TT1
Chiang, SH1
Wu, SJ1
Hsiao, KJ1
Miachon, S1
Augier, S1
Jouvenet, M1
Boucher, P1
Vallon, JJ1
Banasr, M1
Hery, M1
Brezun, JM1
Daszuta, A1
Engel, J2
Clemens, JA2
Roush, ME1
Fuller, RW1
Shaar, CJ1
Yanai, J1
Sze, PY1
Ginsburg, BE1
Treilhou-Lahille, F1
Satli, MA1
Rivas Nuñez, CJ1
Fernandez Martin, F1
Hernández, RJ1
Bakke, JL1
Lawrence, NL1
Robinson, SA1
Bennett, J1
Bowers, C1
Breese, GR1
Vogel, RA1
Kuhn, CM1
Mailman, RB1
Mueller, RA1
Schanberg, SM1
Partanen, S1
Kato, Y1
Grosso, DS1
Gawienowski, AM1
Shirama, K1
Takeo, Y1
Shimizu, K1
Maekawa, K1
Mokler, DJ1
Sullivan, SA1
Winterson, BJ1
Lipson, AH1
Earl, JW1
Wilcken, B1
Yu, JS1
O'Halloran, M1
Cotton, RG1
Acharya, SB1
Goswami, NG1
Debnath, PK1
Ieni, JR1
Thurmond, JB1
Lucot, JB1
Seiden, LS1
Peters, DA1
Murai, I1
Ben-Jonathan, N1
Hole, K1
Tindal, JS1
Boulton, CS1
Handley, SL1
Takahashi, M1
Homma, K1
Suzuki, Y1
Wardle, EN1
Loo, YH1
Labhsetwar, AP1
Snyder, SH1
Axelrod, J1
Wurtman, RJ1
Wigglesworth, JS1
Whyley, GA1
Pearse, AG1
Carvalheira, AF1
Meyerson, BJ2
Sawyer, CH1
Tsukuda, A1
Hoyland, VJ1
Shillito, EE1
Vogt, M1

Reviews

5 reviews available for 5-hydroxytryptophan and Pregnancy

ArticleYear
Selected integrative medicine treatments for depression: considerations for women.
    Journal of the American Medical Women's Association (1972), 2004,Summer, Volume: 59, Issue:3

    Topics: 5-Hydroxytryptophan; Acupuncture Therapy; Complementary Therapies; Depressive Disorder; Exercise The

2004
[Biochemical aspects of migraine].
    Revista clinica espanola, 1975, Oct-31, Volume: 139, Issue:2

    Topics: 5-Hydroxytryptophan; Age Factors; Ammonia; Blood Platelet Disorders; Female; Humans; Menstruation; M

1975
Carbonyl compound-induced fluorescence of biogenic monoamines in the endocrine cells of the hypophysis.
    Progress in histochemistry and cytochemistry, 1978, Volume: 10, Issue:3

    Topics: 5-Hydroxytryptophan; Acetates; Animals; Biogenic Amines; Catecholamines; Chemical Phenomena; Chemist

1978
[Determination of serum prolactin].
    Nihon rinsho. Japanese journal of clinical medicine, 1976, Volume: 34 suppl

    Topics: 5-Hydroxytryptophan; Amenorrhea; Brain Diseases; Chlorpromazine; Female; Galactorrhea; Humans; Hypot

1976
Hypothalamic control of secretion and release of prolactin.
    Journal of reproduction and fertility, 1974, Volume: 39, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Biogenic Amines; Birds; Calcium; Central Nervous System; Circadian Rhy

1974

Trials

2 trials available for 5-hydroxytryptophan and Pregnancy

ArticleYear
Increasing serotonin concentrations alter calcium metabolism in periparturient dairy goats.
    Journal of animal science, 2022, Mar-01, Volume: 100, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Calcium; Female; Goats; Lactation; Pregnancy; Serotonin

2022
Endocrine and metabolic changes in transition dairy cows are affected by prepartum infusions of a serotonin precursor.
    Journal of dairy science, 2017, Volume: 100, Issue:6

    Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Calcium; Cattle; Female; Glucagon; Haptoglobins; Homeosta

2017

Other Studies

69 other studies available for 5-hydroxytryptophan and Pregnancy

ArticleYear
Exploration of urinary metabolite dynamicity for early detection of pregnancy in water buffaloes.
    Scientific reports, 2022, 09-29, Volume: 12, Issue:1

    Topics: 5-Hydroxytryptophan; Amino Acids, Aromatic; Animals; Bison; Buffaloes; Female; Pregnancy; Tryptophan

2022
Simultaneous quantification of tryptophan metabolites by liquid chromatography tandem mass spectrometry during early human pregnancy.
    Clinical chemistry and laboratory medicine, 2023, 02-23, Volume: 61, Issue:3

    Topics: 5-Hydroxytryptophan; Chromatography, High Pressure Liquid; Chromatography, Liquid; Female; Humans; H

2023
Simultaneous quantification of tryptophan metabolites by liquid chromatography tandem mass spectrometry during early human pregnancy.
    Clinical chemistry and laboratory medicine, 2023, 02-23, Volume: 61, Issue:3

    Topics: 5-Hydroxytryptophan; Chromatography, High Pressure Liquid; Chromatography, Liquid; Female; Humans; H

2023
Simultaneous quantification of tryptophan metabolites by liquid chromatography tandem mass spectrometry during early human pregnancy.
    Clinical chemistry and laboratory medicine, 2023, 02-23, Volume: 61, Issue:3

    Topics: 5-Hydroxytryptophan; Chromatography, High Pressure Liquid; Chromatography, Liquid; Female; Humans; H

2023
Simultaneous quantification of tryptophan metabolites by liquid chromatography tandem mass spectrometry during early human pregnancy.
    Clinical chemistry and laboratory medicine, 2023, 02-23, Volume: 61, Issue:3

    Topics: 5-Hydroxytryptophan; Chromatography, High Pressure Liquid; Chromatography, Liquid; Female; Humans; H

2023
5-Hydroxytryptophan inhibits β-casein biosynthesis and promotes goat mammary epithelial cell apoptosis through the JAK2/STAT5a axis and the HTR7.
    Journal of animal science, 2023, Jan-03, Volume: 101

    Topics: 5-Hydroxytryptophan; Animals; Apoptosis; Caseins; Epithelial Cells; Female; Goats; Lactation; Mammar

2023
Metabolomic markers of antepartum depression and suicidal ideation.
    Journal of affective disorders, 2020, 02-01, Volume: 262

    Topics: 5-Hydroxytryptophan; Adult; Betaine; Biomarkers; Carnitine; Citrulline; Cross-Sectional Studies; Dep

2020
Comparative assessment of toxic responses in 3D embryoid body differentiation model and mouse early embryos treated with 5-hydroxytryptophan.
    Archives of toxicology, 2021, Volume: 95, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Cell Death; Cell Differentiation; Cells, Cultured; Dose-Response Relat

2021
Improved strength on 5-hydroxytryptophan and carbidopa in spinal cord atrophy.
    Journal of the neurological sciences, 2017, Jul-15, Volume: 378

    Topics: 5-Hydroxytryptophan; Adult; Atrophy; Carbidopa; Central Nervous System Agents; Fatal Outcome; Female

2017
Short communication: Supplementation of colostrum and milk with 5-hydroxy-l-tryptophan affects immune factors but not growth performance in newborn calves.
    Journal of dairy science, 2018, Volume: 101, Issue:1

    Topics: 5-Hydroxytryptophan; Animal Feed; Animals; Animals, Newborn; Birth Weight; Cattle; Colostrum; Dietar

2018
Feeding 5-hydroxy-l-tryptophan during the transition from pregnancy to lactation increases calcium mobilization from bone in rats.
    Domestic animal endocrinology, 2013, Volume: 44, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Bone and Bones; Bone Remodeling; Calcium; Dietary Supplements; Female;

2013
Serotonin (5-HT) affects expression of liver metabolic enzymes and mammary gland glucose transporters during the transition from pregnancy to lactation.
    PloS one, 2013, Volume: 8, Issue:2

    Topics: 5-Hydroxytryptophan; AMP-Activated Protein Kinases; Animals; Biomarkers; Blood Glucose; Energy Metab

2013
Increasing serotonin concentrations alter calcium and energy metabolism in dairy cows.
    The Journal of endocrinology, 2015, Volume: 226, Issue:1

    Topics: 3-Hydroxybutyric Acid; 5-Hydroxytryptophan; Animals; Blood Glucose; Calcium; Cattle; Energy Metaboli

2015
Maternal Inflammation Disrupts Fetal Neurodevelopment via Increased Placental Output of Serotonin to the Fetal Brain.
    The Journal of neuroscience : the official journal of the Society for Neuroscience, 2016, 06-01, Volume: 36, Issue:22

    Topics: 5-Hydroxytryptophan; Animals; Brain; Cytokines; Disease Models, Animal; Female; Fenclonine; Fetal De

2016
Rumination time and reticuloruminal temperature as possible predictors of dystocia in dairy cows.
    Journal of dairy science, 2017, Volume: 100, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Body Temperature; Calcium; Cattle; Cattle Diseases; Colostrum; Dystoci

2017
Increased serum serotonin improves parturient calcium homeostasis in dairy cows.
    Journal of dairy science, 2017, Volume: 100, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Blood Glucose; Body Fluids; Calcium; Cattle; Cattle Diseases; Colostru

2017
Anxiety-like behavior and cognitive flexibility in adult rats perinatally exposed to increased serotonin concentrations.
    Behavioural brain research, 2012, Apr-21, Volume: 230, Issue:1

    Topics: 5-Hydroxytryptophan; Analysis of Variance; Animals; Antidepressive Agents, Second-Generation; Anxiet

2012
[PROCEEDINGS AND RESEARCH REPORTS OF THE 4TH SEROTONIN RESEARCH MEETING. ON REPORTS FROM VARIOUS INSTITUTIONS].
    Arerugi = [Allergy], 1964, Volume: 13

    Topics: 5-Hydroxytryptophan; Blood Chemical Analysis; Female; Humans; Hydroxyindoleacetic Acid; Indoleacetic

1964
Serum tryptophan and 5-hydroxytryptophan at birth and during post-partum days.
    Advances in experimental medicine and biology, 2003, Volume: 527

    Topics: 5-Hydroxytryptophan; Cesarean Section; Delivery, Obstetric; Female; Fetal Blood; Humans; Infant, New

2003
Diffusion tensor images in children with early-treated, chronic, malignant phenylketonuric: correlation with intelligence assessment.
    AJNR. American journal of neuroradiology, 2004, Volume: 25, Issue:9

    Topics: 5-Hydroxytryptophan; Axons; Biopterins; Brain Damage, Chronic; Cerebral Cortex; Child; Child, Presch

2004
Pregnant rats treated with a serotonin precursor have reduced fetal weight and lower plasma volume and kallikrein levels.
    Hypertension (Dallas, Tex. : 1979), 2007, Volume: 50, Issue:4

    Topics: 5-Hydroxytryptophan; Aldosterone; Animals; Blood Pressure; Creatinine; Disease Models, Animal; Femal

2007
Reinstatement of LH surges by serotonin neuroleptics in aging, constant estrous rats.
    Neurobiology of aging, 1982,Fall, Volume: 3, Issue:3

    Topics: 5-Hydroxytryptophan; Aging; alpha-Methyltyrosine; Animals; Antipsychotic Agents; Castration; Estradi

1982
5-Hydroxytryptamine synthesis and metabolism in discrete nuclei of the rat brain during surges of prolactin associated with restraint stress or suckling.
    Neuroendocrinology, 1984, Volume: 38, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Corpus Striatum; Female; Hydroxyindoleacetic Acid; Hypothalamus; Lacta

1984
[Effect of 6-hydroxydopamine and 5,6-Dihydroxytryptophan on the luliberin and luteinizing hormone levels in female rats under constant illumination].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1983, Volume: 69, Issue:9

    Topics: 5-Hydroxytryptophan; Animals; Desipramine; Estrus; Female; Gonadotropin-Releasing Hormone; Hydroxydo

1983
Effects of manipulating serotonin on the incidence of ovulation in the rat.
    The Journal of endocrinology, 1980, Volume: 87, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Estradiol; Estrogens; Estrus; Female; Fenclonine; Injection

1980
[The hypothalamo-hypophyseo-ovarian systems in rats after deafferentiation of the mediobasal hypothalamus].
    Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova, 1982, Volume: 68, Issue:9

    Topics: 5-Hydroxytryptophan; Afferent Pathways; Animals; Brain Chemistry; Denervation; Estrus; Female; Gonad

1982
Hormone ontogeny in the ovine fetus. XI. The Serotoninergic regulation of growth hormone and prolactin secretion.
    Endocrinology, 1980, Volume: 107, Issue:5

    Topics: 5-Hydroxytryptophan; Animals; Female; Fluoxetine; Gestational Age; Growth Hormone; Hypothalamo-Hypop

1980
Effect of 5-hydroxytryptophan on electrocortical activity and breathing movements of fetal sheep.
    American journal of obstetrics and gynecology, 1981, Oct-01, Volume: 141, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Cerebral Cortex; Electroencephalography; Electromyography; Electroocul

1981
Suppression of prolactin secretion by benzodiazepines in vivo.
    Neuroendocrinology, 1982, Volume: 34, Issue:5

    Topics: 5-Hydroxytryptophan; Animals; Benzodiazepines; Diazepam; Dose-Response Relationship, Drug; Female; F

1982
Age-dependent reduction in maximum electroshock convulsive threshold associated with decreased concentrations of brain monoamines.
    Pharmacology, biochemistry, and behavior, 1982, Volume: 16, Issue:3

    Topics: 5-Hydroxytryptophan; 5,7-Dihydroxytryptamine; Aging; Animals; Biogenic Amines; Brain Chemistry; Elec

1982
Survival of neonatal rats during hypoxia after monoamine stimulating agents.
    Acta pharmacologica et toxicologica, 1982, Volume: 50, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Animals, Newborn; Apomorphine; Biogenic Amines; Carbidopa; Female; Hyp

1982
Infertility in transgenic mice overexpressing the bovine growth hormone gene: disruption of the neuroendocrine control of prolactin secretion during pregnancy.
    Biology of reproduction, 1995, Volume: 52, Issue:5

    Topics: 5-Hydroxytryptophan; Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Cattle; Domperidone; Dop

1995
Measurement of 5-hydroxytryptamine and 5-hydroxyindoleacetic acid in cultured rat mesencephalic neurons by high-performance liquid chromatography with electrochemical detection.
    Journal of chromatography, 1993, Apr-02, Volume: 613, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Cells, Cultured; Chromatography, High Pressure Liquid; Electrochemistr

1993
The effects of 'sleep promoting agents' on behavioural state in the ovine fetus.
    Brain research. Developmental brain research, 1997, Oct-20, Volume: 103, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Carbachol; Cerebral Ventricles; Electrocardiography; Electrooculograph

1997
Receptors and neurotransmitters involved in the dual modulation of prolactin release by the serotoninergic system in pregnant and lactating rats.
    Journal of reproduction and fertility, 1999, Volume: 116, Issue:2

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Adrenergic alpha-Antagonists; Adrenergi

1999
Tetrahydrobiopterin-deficient hyperphenylalaninemia in the Chinese.
    Clinica chimica acta; international journal of clinical chemistry, 2001, Volume: 313, Issue:1-2

    Topics: 5-Hydroxytryptophan; Biopterins; Diagnosis, Differential; Dihydropteridine Reductase; Female; Geneti

2001
Nutritional parameters modify muricidal behavior of male Wistar rats: preventive effects of amino acids and 4' Cl diazepam.
    Life sciences, 2001, Oct-26, Volume: 69, Issue:23

    Topics: 5-Hydroxytryptophan; Aggression; Animals; Behavior, Animal; Benzodiazepinones; Cholesterol; Diet; Di

2001
Serotonin mediates oestrogen stimulation of cell proliferation in the adult dentate gyrus.
    The European journal of neuroscience, 2001, Volume: 14, Issue:9

    Topics: 5-Hydroxytryptophan; Animals; Astrocytes; Bromodeoxyuridine; Cell Count; Cell Division; Dentate Gyru

2001
Effect of hypoxia on monoamine synthesis in brains of developing rats. III. Various O2 levels.
    Biology of the neonate, 1978, Volume: 34, Issue:1-2

    Topics: 5-Hydroxytryptophan; Animals; Animals, Newborn; Brain; Dihydroxyphenylalanine; Female; Hypoxia; Nore

1978
Changes in luteinizing hormone and prolactin control mechanisms produced by glutamate lesions of the arcuate nucleus.
    Endocrinology, 1978, Volume: 103, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Animals, Newborn; Castration; Chlorpromazine; Dopamine; Estradiol; Fem

1978
Effects of aminergic drugs and glutamic acid on audiogenic seizures induced by early exposure to ethanol.
    Epilepsia, 1975, Volume: 16, Issue:1

    Topics: 5-Hydroxytryptophan; Acoustic Stimulation; Animals; Behavior, Animal; Dihydroxyphenylalanine; Drug I

1975
[Uptake and storage of indolamines in the ultimobranchial body of the fetal murine thyroid. 1-Autoradiographic histological study].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1976, Volume: 170, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Autoradiography; Female; Mice; Pregnancy; Thyroid Gland; Tritium; Ulti

1976
Serotonin involvement in the control of phasic luteinizing hormone release in the rat: evidence for a critical period.
    The Journal of endocrinology, 1979, Volume: 82, Issue:1

    Topics: 5-Hydroxytryptophan; 5,6-Dihydroxytryptamine; Animals; Castration; Circadian Rhythm; Estradiol; Fema

1979
[New data on serotoninergic mechanisms in ovulation in the cyclic female rat].
    Comptes rendus des seances de la Societe de biologie et de ses filiales, 1979, Volume: 173, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Diestrus; Estradiol; Female; Fenclonine; Ovulation; Pregnancy; Proestr

1979
Na+-K+-ATPase activity in the brain cortex of rats ontogenetically malnourished, and treated with serotonin precursors.
    Brain research, 1979, Feb-23, Volume: 162, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Cerebral Cortex; Dose-Response Relationship, Drug; Enzyme Activation;

1979
Late endocrine effects of L-dopa, 5-HTP, and 6-OH-dopa administered to neonatal rats.
    Neuroendocrinology, 1978, Volume: 25, Issue:5

    Topics: 5-Hydroxytryptophan; Adrenal Glands; Animals; Animals, Newborn; Estrus; Female; Follicle Stimulating

1978
Behavioral and prolactin responses to 5-hydroxytryptophan in rats treated during development with 5,7-dihydroxytryptamine.
    Brain research, 1978, Oct-27, Volume: 155, Issue:2

    Topics: 5-Hydroxytryptophan; 5,7-Dihydroxytryptamine; Animals; Animals, Newborn; Behavior, Animal; Benserazi

1978
Effects of serotonin neurotoxins on pituitary hormone release.
    Annals of the New York Academy of Sciences, 1978, Jun-12, Volume: 305

    Topics: 5-Hydroxytryptophan; 5,7-Dihydroxytryptamine; Animals; Female; Fluoxetine; Growth Hormone; Luteinizi

1978
Modification of rat uterine monoamine oxidase activity by steroid hormones.
    The Journal of endocrinology, 1975, Volume: 65, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Castration; Cerebellum; Estradiol; Estrus; Female; Gonadal Steroid Hor

1975
Inhibitory effect of 5-hydroxytryptophane on the induction of persistent estrus by androgen in the rat.
    Endocrinologia japonica, 1975, Volume: 22, Issue:6

    Topics: 5-Hydroxytryptophan; Animals; Dihydroxyphenylalanine; Dopamine; Estrus; Female; Pregnancy; Rats; Ser

1975
Behaviors induced by 5-hydroxytryptophan in neonatal, preweaning, postweaning, and adult Sprague-Dawley rats.
    Pharmacology, biochemistry, and behavior, 1992, Volume: 42, Issue:3

    Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Aging; Amphetamines; Animals; Animals,

1992
Successful treatment of dihydropteridine reductase deficiency, with an interesting effect of 5-hydroxytryptophan deficiency on sleep patterns.
    Journal of inherited metabolic disease, 1991, Volume: 14, Issue:1

    Topics: 5-Hydroxytryptophan; Female; Humans; Levodopa; Male; Phenylketonurias; Pregnancy; Prenatal Diagnosis

1991
Uterine and placental 5-HT profile in different gestational period of albino rats.
    Indian journal of experimental biology, 1989, Volume: 27, Issue:6

    Topics: 5-Hydroxytryptophan; Animals; Cyproheptadine; Diethylstilbestrol; Estrus; Female; Placenta; Pregnanc

1989
Effect of serotonin antagonists on prolactin and progesterone secretion in rats: evidence that the stimulatory and inhibitory actions of serotonin on prolactin release may be mediated through different receptors.
    The Journal of endocrinology, 1988, Volume: 117, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Female; Fenclonine; Fluoxetine; Indoles; Ketanserin; Pregnancy; Proest

1988
Maternal aggression in mice: effects of treatments with PCPA, 5-HTP and 5-HT receptor antagonists.
    European journal of pharmacology, 1985, May-08, Volume: 111, Issue:2

    Topics: 5-Hydroxytryptophan; Aggression; Animals; Biogenic Amines; Brain Chemistry; Female; Fenclonine; Huma

1985
Effects of serotonergic agonists and antagonists on the locomotor activity of neonatal rats.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:3

    Topics: 5-Hydroxytryptophan; Aging; Animals; Animals, Newborn; Cinanserin; Female; Methiothepin; Methysergid

1986
Prenatal stress increases the behavioral response to serotonin agonists and alters open field behavior in the rat.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 25, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Animals, Newborn; Behavior, Animal; Carbidopa; Crowding; Female; Metho

1986
Posterior pituitary lobectomy abolishes the suckling-induced rise in prolactin (PRL): evidence for a PRL-releasing factor in the posterior pituitary.
    Endocrinology, 1987, Volume: 121, Issue:1

    Topics: 5-Hydroxytryptophan; alpha-Methyltyrosine; Animals; Deamino Arginine Vasopressin; Dopamine; Drinking

1987
Reduced 5-hydroxyindole synthesis reduces postnatal brain growth in rats.
    European journal of pharmacology, 1972, Volume: 18, Issue:3

    Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Body Weight; Brain; Brain Chemistry; Drug Interactions; F

1972
Regional changes in monoamine levels and in the rate of tyrosine and tryptophan hydroxylation in 4 week old offspring of nursing mothers treated with the neuroleptic drug penfluridol.
    Naunyn-Schmiedeberg's archives of pharmacology, 1974, Volume: 282, Issue:4

    Topics: 5-Hydroxytryptophan; Age Factors; Animals; Animals, Newborn; Biogenic Amines; Body Weight; Brain; Br

1974
Factors modifying the head-twitch response to 5-hydroxytryptophan.
    Psychopharmacologia, 1973, Jul-19, Volume: 31, Issue:3

    Topics: 5-Hydroxytryptophan; Anesthesia, Local; Animals; Circadian Rhythm; Ear, External; Estrus; Female; He

1973
Resumption of cyclicity in light induced persistent estrus by treatment with serotonin or its precursor.
    Endocrinologia japonica, 1973, Volume: 20, Issue:3

    Topics: 5-Hydroxytryptophan; Anesthesia; Animals; Estrus; Eye; Female; In Vitro Techniques; Injections; Inje

1973
The relevance of intravascular coagulation to pre-eclampsia.
    Bibliotheca anatomica, 1973, Volume: 12

    Topics: 5-Hydroxytryptophan; Abruptio Placentae; Animals; Blood Coagulation Factors; Desoxycorticosterone; D

1973
Serotonin deficiency in experimental hyperphenylalaninemia.
    Journal of neurochemistry, 1974, Volume: 23, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Biphenyl Compounds; Brain; Carbon Radioisotopes; Carboxy-Lyases; Dopa

1974
Effects of serotonin on spontaneous ovulation in rats.
    Nature, 1971, Jan-15, Volume: 229, Issue:5281

    Topics: 5-Hydroxytryptophan; Animals; Depression, Chemical; Estrus; Ethanol; Female; Indoles; Methysergide;

1971
Effect of gonadal hormones on aromatic amino acid decarboxylase in the rat uterus.
    Endocrinology, 1966, Volume: 78, Issue:6

    Topics: 5-Hydroxytryptophan; Animals; Carboxy-Lyases; Castration; Estradiol; Estrus; Female; Hypophysectomy;

1966
Rat foetal mortality after 5-hydroxytryptophan and serotonin administration.
    The Journal of pathology and bacteriology, 1967, Volume: 94, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Blood Vessels; Female; Fetal Death; Maternal-Fetal Exchange; Placenta;

1967
Cytochemical evidence for an ultimobranchial origin of rodent thyroid C cells.
    Nature, 1967, May-27, Volume: 214, Issue:5091

    Topics: 5-Hydroxytryptophan; Animals; Calcitonin; Dihydroxyphenylalanine; Female; Ganglia, Autonomic; Histoc

1967
Monoamines and ovulation in the rat.
    Endocrinology, 1968, Volume: 83, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Animals, Newborn; Brain; Catecholamines; Depression, Chemical; Dihydro

1968
[Studies on the relationship between serotonin metabolism and emotional stability in obstetrics and gynecology].
    Igaku kenkyu. Acta medica, 1969, Volume: 39, Issue:4

    Topics: 5-Hydroxytryptophan; Adult; Autonomic Nervous System; Castration; Delivery, Obstetric; Emotions; Fem

1969
The effect of parachlorophenylalanine on the behaviour of cats.
    British journal of pharmacology, 1970, Volume: 40, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Cats; Estrus; Female; Male; Phenylalanine; Pregnancy

1970
Monoamines and hormone activated oestrous behaviour in the ovariectomized hamster.
    Psychopharmacologia, 1970, Aug-19, Volume: 18, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Biogenic Amines; Brain; Castration; Cricetinae; Depression, Chemical;

1970