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5-hydroxytryptophan and Panic Attacks

5-hydroxytryptophan has been researched along with Panic Attacks in 5 studies

5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.

Research Excerpts

ExcerptRelevanceReference
"Salivary cortisol levels were measured in 24 panic disorder patients and 24 healthy volunteers, following ingestion of 200 mg L-5-hydroxytryptophan or placebo."9.10L-5-hydroxytryptophan induced increase in salivary cortisol in panic disorder patients and healthy volunteers. ( Griez, E; Nicolson, N; Schruers, K; van Diest, R, 2002)
"The results show that L-5-hydroxytryptophan stimulated salivary cortisol is a useful probe of serotonin function in healthy volunteers as well as panic disorder patients, and provide some evidence against a serotonin receptor hypersensitivity in panic disorder."9.10L-5-hydroxytryptophan induced increase in salivary cortisol in panic disorder patients and healthy volunteers. ( Griez, E; Nicolson, N; Schruers, K; van Diest, R, 2002)
" In order to evaluate the influence of 5-HT-related gene variants on the vulnerability to panic attacks, we genotyped 32 healthy volunteers who participated in the study of the effect of 5-hydroxytryptophan on panic attacks induced with cholecystokinin tetrapeptide (CCK-4)."7.72Association between serotonin-related genetic polymorphisms and CCK-4-induced panic attacks with or without 5-hydroxytryptophan pretreatment in healthy volunteers. ( Lang, A; Maron, E; Shlik, J; Tasa, G; Tõru, I; Vasar, V, 2004)
"L-5-Hydroxytryptophan acts to inhibit panic, which supports a modulatory role of serotonin in panic disorder."6.70Acute L-5-hydroxytryptophan administration inhibits carbon dioxide-induced panic in panic disorder patients. ( Griez, E; Overbeek, T; Schruers, K; van Diest, R, 2002)
"Salivary cortisol levels were measured in 24 panic disorder patients and 24 healthy volunteers, following ingestion of 200 mg L-5-hydroxytryptophan or placebo."5.10L-5-hydroxytryptophan induced increase in salivary cortisol in panic disorder patients and healthy volunteers. ( Griez, E; Nicolson, N; Schruers, K; van Diest, R, 2002)
"The results show that L-5-hydroxytryptophan stimulated salivary cortisol is a useful probe of serotonin function in healthy volunteers as well as panic disorder patients, and provide some evidence against a serotonin receptor hypersensitivity in panic disorder."5.10L-5-hydroxytryptophan induced increase in salivary cortisol in panic disorder patients and healthy volunteers. ( Griez, E; Nicolson, N; Schruers, K; van Diest, R, 2002)
"To investigate the role of serotonin (5-HT) in the pathophysiology of panic disorder (PD) a challenge test with L-5-hydroxytryptophan (5-HTP) was conducted."5.08Behavioral, neuroendocrine and biochemical effects of different doses of 5-HTP in panic disorder. ( Den Boer, JA; Slaap, BR; van Vliet, IM; Westenberg, HG, 1996)
" In order to evaluate the influence of 5-HT-related gene variants on the vulnerability to panic attacks, we genotyped 32 healthy volunteers who participated in the study of the effect of 5-hydroxytryptophan on panic attacks induced with cholecystokinin tetrapeptide (CCK-4)."3.72Association between serotonin-related genetic polymorphisms and CCK-4-induced panic attacks with or without 5-hydroxytryptophan pretreatment in healthy volunteers. ( Lang, A; Maron, E; Shlik, J; Tasa, G; Tõru, I; Vasar, V, 2004)
"L-5-Hydroxytryptophan acts to inhibit panic, which supports a modulatory role of serotonin in panic disorder."2.70Acute L-5-hydroxytryptophan administration inhibits carbon dioxide-induced panic in panic disorder patients. ( Griez, E; Overbeek, T; Schruers, K; van Diest, R, 2002)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's4 (80.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schruers, K2
van Diest, R2
Overbeek, T1
Griez, E2
Maron, E2
Tõru, I2
Vasar, V2
Shlik, J2
Tasa, G1
Lang, A1
van Vliet, IM1
Slaap, BR1
Westenberg, HG1
Den Boer, JA1
Nicolson, N1

Trials

4 trials available for 5-hydroxytryptophan and Panic Attacks

ArticleYear
Acute L-5-hydroxytryptophan administration inhibits carbon dioxide-induced panic in panic disorder patients.
    Psychiatry research, 2002, Dec-30, Volume: 113, Issue:3

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Brain; Carbon Dioxide; Double-Blind Method; Drug Admin

2002
The effect of 5-hydroxytryptophan on cholecystokinin-4-induced panic attacks in healthy volunteers.
    Journal of psychopharmacology (Oxford, England), 2004, Volume: 18, Issue:2

    Topics: 5-Hydroxytryptophan; Administration, Oral; Adolescent; Adult; Capsules; Cognition Disorders; Double-

2004
Behavioral, neuroendocrine and biochemical effects of different doses of 5-HTP in panic disorder.
    European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology, 1996, Volume: 6, Issue:2

    Topics: 5-Hydroxytryptophan; Adult; Affect; Dose-Response Relationship, Drug; Double-Blind Method; Female; H

1996
L-5-hydroxytryptophan induced increase in salivary cortisol in panic disorder patients and healthy volunteers.
    Psychopharmacology, 2002, Volume: 161, Issue:4

    Topics: 5-Hydroxytryptophan; Adult; Analysis of Variance; Double-Blind Method; Female; Humans; Hydrocortison

2002

Other Studies

1 other study available for 5-hydroxytryptophan and Panic Attacks

ArticleYear
Association between serotonin-related genetic polymorphisms and CCK-4-induced panic attacks with or without 5-hydroxytryptophan pretreatment in healthy volunteers.
    The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry, 2004, Volume: 5, Issue:3

    Topics: 5-Hydroxytryptophan; Alleles; DNA Primers; Female; Genotype; Humans; Male; Membrane Glycoproteins; M

2004