5-hydroxytryptophan has been researched along with Neuroendocrine Tumors in 16 studies
5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.
Neuroendocrine Tumors: Tumors whose cells possess secretory granules and originate from the neuroectoderm, i.e., the cells of the ectoblast or epiblast that program the neuroendocrine system. Common properties across most neuroendocrine tumors include ectopic hormone production (often via APUD CELLS), the presence of tumor-associated antigens, and isozyme composition.
| Excerpt | Relevance | Reference |
|---|---|---|
| "[(11)C]-5-Hydroxytryptophan ([(11)C]HTP) and 6-[(18)F]fluoro-3,4-dihydroxy-l-phenylalanine ([(18)F]FDOPA) are used to image neuroendocrine tumors with positron emission tomography." | 3.74 | Manipulation of [11C]-5-hydroxytryptophan and 6-[18F]fluoro-3,4-dihydroxy-L-phenylalanine accumulation in neuroendocrine tumor cells. ( Brouwers, AH; de Vries, EG; Dierckx, RA; Doorduin, J; Elsinga, PH; Jager, PL; Kema, IP; Koopmans, KP; Neels, OC; Timmer-Bosscha, H; van Waarde, A; Vercauteren, L, 2008) |
| "Direct-matrix derivatization in combination with LC-MS/MS is a powerful tool for the simultaneous quantification of all tryptophan-related indoles in platelet-rich plasma." | 1.51 | Quantitative Profiling of Platelet-Rich Plasma Indole Markers by Direct-Matrix Derivatization Combined with LC-MS/MS in Patients with Neuroendocrine Tumors. ( Bouma, G; de Hosson, LD; de Vries, EGE; Kats-Ugurlu, G; Kema, IP; Peters, MAM; van Faassen, M; Walenkamp, AME, 2019) |
| "MRI detected more liver metastases than 5-HTP PET/CT." | 1.46 | Whole-body MRI including diffusion-weighted MRI compared with 5-HTP PET/CT in the detection of neuroendocrine tumors. ( Ahlström, H; Caballero-Corbalán, J; Carlbom, L; Eriksson, B; Granberg, D; Sörensen, J, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 5 (31.25) | 29.6817 |
| 2010's | 9 (56.25) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| van Faassen, M | 1 |
| Bouma, G | 1 |
| de Hosson, LD | 1 |
| Peters, MAM | 1 |
| Kats-Ugurlu, G | 1 |
| de Vries, EGE | 1 |
| Walenkamp, AME | 1 |
| Kema, IP | 3 |
| Koopmans, KP | 3 |
| Glaudemans, AW | 1 |
| Tőke, J | 1 |
| Czirják, G | 1 |
| Tóth, M | 1 |
| Rácz, K | 1 |
| Patócs, A | 1 |
| van Asselt, SJ | 1 |
| Brouwers, AH | 2 |
| van Dullemen, HM | 1 |
| van der Jagt, EJ | 1 |
| Bongaerts, AH | 1 |
| Valk, GD | 1 |
| Timmers, HJ | 1 |
| de Herder, WW | 1 |
| Feelders, RA | 1 |
| Fockens, P | 1 |
| Sluiter, WJ | 1 |
| de Vries, EG | 2 |
| Links, TP | 1 |
| Ambrosini, V | 1 |
| Morigi, JJ | 1 |
| Nanni, C | 1 |
| Castellucci, P | 1 |
| Fanti, S | 1 |
| Carlbom, L | 1 |
| Caballero-Corbalán, J | 1 |
| Granberg, D | 1 |
| Sörensen, J | 1 |
| Eriksson, B | 5 |
| Ahlström, H | 3 |
| Neels, OC | 1 |
| Jager, PL | 1 |
| Vercauteren, L | 1 |
| van Waarde, A | 1 |
| Doorduin, J | 1 |
| Timmer-Bosscha, H | 1 |
| Dierckx, RA | 1 |
| Elsinga, PH | 1 |
| Nikolaou, A | 1 |
| Thomas, D | 1 |
| Kampanellou, C | 1 |
| Alexandraki, K | 1 |
| Andersson, LG | 1 |
| Sundin, A | 6 |
| Kaltsas, G | 1 |
| Van Binnebeek, S | 1 |
| Karges, W | 1 |
| Mottaghy, FM | 1 |
| Norlén, O | 1 |
| Nilsson, A | 1 |
| Krause, J | 1 |
| Stålberg, P | 1 |
| Hellman, P | 1 |
| Bergström, M | 4 |
| Juhlin, C | 2 |
| Orlefors, H | 4 |
| Oberg, K | 4 |
| Långström, B | 4 |
| Garske, U | 2 |
| Skogseid, B | 1 |
| Lilja, A | 2 |
| Bjurling, P | 2 |
| Lindner, KJ | 1 |
| Bombardieri, E | 1 |
| Maccauro, M | 1 |
| De Deckere, E | 1 |
| Savelli, G | 1 |
| Chiti, A | 1 |
6 reviews available for 5-hydroxytryptophan and Neuroendocrine Tumors
| Article | Year |
|---|---|
Other PET tracers for neuroendocrine tumors.
Topics: 3-Iodobenzylguanidine; 5-Hydroxytryptophan; Carbon Radioisotopes; Humans; Intestinal Neoplasms; Neur | 2014 |
[Significance of biochemical markers in the diagnosis of neuroendocrine tumours and for the follow-up of patients].
Topics: 5-Hydroxytryptophan; Biomarkers, Tumor; Chorionic Gonadotropin; Chromogranins; Glucagon; Humans; Hyd | 2014 |
Current status of PET imaging of neuroendocrine tumours ([18F]FDOPA, [68Ga]tracers, [11C]/[18F]-HTP).
Topics: 5-Hydroxytryptophan; Carbon Radioisotopes; Dihydroxyphenylalanine; Gallium Radioisotopes; Humans; Im | 2015 |
The role of PET in localization of neuroendocrine and adrenocortical tumors.
Topics: 5-Hydroxytryptophan; Adrenal Gland Neoplasms; Carbon Radioisotopes; Etomidate; Fluorine Radioisotope | 2002 |
Nuclear imaging of neuroendocrine tumours.
Topics: 3-Iodobenzylguanidine; 5-Hydroxytryptophan; Carbidopa; Glucose-6-Phosphate; Humans; Levodopa; Neuroe | 2007 |
Nuclear medicine imaging of neuroendocrine tumours.
Topics: 3-Iodobenzylguanidine; 5-Hydroxytryptophan; Antibodies, Monoclonal; Fluorodeoxyglucose F18; Humans; | 2001 |
2 trials available for 5-hydroxytryptophan and Neuroendocrine Tumors
| Article | Year |
|---|---|
11C-5-hydroxytryptophan positron emission tomography after radiofrequency ablation of neuroendocrine tumor liver metastases.
Topics: 5-Hydroxytryptophan; Ablation Techniques; Carbon Radioisotopes; Follow-Up Studies; Humans; Liver Neo | 2012 |
Positron-emission tomography as a radiological technique in neuroendocrine gastrointestinal tumors.
Topics: 5-Hydroxytryptophan; Carbon Radioisotopes; Carcinoid Tumor; Gastrointestinal Neoplasms; Humans; Inte | 1994 |
8 other studies available for 5-hydroxytryptophan and Neuroendocrine Tumors
| Article | Year |
|---|---|
Quantitative Profiling of Platelet-Rich Plasma Indole Markers by Direct-Matrix Derivatization Combined with LC-MS/MS in Patients with Neuroendocrine Tumors.
Topics: 5-Hydroxytryptophan; Adult; Aged; Biomarkers, Tumor; Chromatography, Liquid; Female; Humans; Hydroxy | 2019 |
EUS is superior for detection of pancreatic lesions compared with standard imaging in patients with multiple endocrine neoplasia type 1.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Carbon Radioisotopes; Cross-Sectional Studies; Early D | 2015 |
Whole-body MRI including diffusion-weighted MRI compared with 5-HTP PET/CT in the detection of neuroendocrine tumors.
Topics: 5-Hydroxytryptophan; Adult; Aged; Bone Neoplasms; Contrast Media; Diffusion Magnetic Resonance Imagi | 2017 |
Manipulation of [11C]-5-hydroxytryptophan and 6-[18F]fluoro-3,4-dihydroxy-L-phenylalanine accumulation in neuroendocrine tumor cells.
Topics: 5-Hydroxytryptophan; Animals; Cell Line, Tumor; Dihydroxyphenylalanine; Humans; Male; Mice; Mice, In | 2008 |
The value of 11C-5-hydroxy-tryptophan positron emission tomography in neuroendocrine tumor diagnosis and management: experience from one center.
Topics: 5-Hydroxytryptophan; ACTH Syndrome, Ectopic; Adult; Carbon Radioisotopes; Carcinoid Tumor; Female; H | 2010 |
Functional imaging of neuroendocrine tumors.
Topics: 5-Hydroxytryptophan; Animals; Contrast Media; Dihydroxyphenylalanine; Dopamine; Ephedrine; Etomidate | 2011 |
Whole-body (11)C-5-hydroxytryptophan positron emission tomography as a universal imaging technique for neuroendocrine tumors: comparison with somatostatin receptor scintigraphy and computed tomography.
Topics: 5-Hydroxytryptophan; Carbon Radioisotopes; Female; Humans; Male; Neuroendocrine Tumors; Pentetic Aci | 2005 |
Positron emission tomography with 5-hydroxytryprophan in neuroendocrine tumors.
Topics: 5-Hydroxytryptophan; Carbon Radioisotopes; Female; Gastrointestinal Neoplasms; Humans; Linear Models | 1998 |