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5-hydroxytryptophan and Neoplasms

5-hydroxytryptophan has been researched along with Neoplasms in 15 studies

5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
" Carcinoid tumors with liver metastases, especially those of midgut origin, produce serotonin via the precursors tryptophan and 5-hydroxytryptophan (5-HTP) and this overproduction contributes to the clinical symptoms of the carcinoid syndrome."5.07Positron emission tomography (PET) in neuroendocrine gastrointestinal tumors. ( Ahlström, H; Bergström, M; Eriksson, B; Långström, B; Lilja, A; Oberg, K, 1993)
"Carcinoid tumors with liver metastases, especially those of midgut origin, produce serotonin via the precursors tryptophan and 5-hydroxytryptophan (5-HTP) and this overproduction contributes to the clinical symptoms of the carcinoid syndrome."2.67Positron emission tomography (PET) in neuroendocrine gastrointestinal tumors. ( Ahlström, H; Bergström, M; Eriksson, B; Långström, B; Lilja, A; Oberg, K, 1993)
"The capillary networks of solid tumors are more permeable and less well organized than those of normal tissue."2.41Small-molecule cytokine inducers causing tumor necrosis. ( Baguley, BC, 2001)
"An atypical case of the malignant carcinoid syndrome, associated with multiple peptic ulcers, is described."1.24A beta-hydroxytryptophan-secreting carcinoid tumour. ( CAMPBELL, AC; GOWENLOCK, AH; PLATT, DS; SNOW, PJ, 1963)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199012 (80.00)18.7374
1990's1 (6.67)18.2507
2000's1 (6.67)29.6817
2010's0 (0.00)24.3611
2020's1 (6.67)2.80

Authors

AuthorsStudies
Liu, Y1
Zhou, N1
Zhou, L1
Wang, J1
Zhou, Y1
Zhang, T1
Fang, Y2
Deng, J1
Gao, Y1
Liang, X1
Lv, J1
Wang, Z1
Xie, J1
Xue, Y1
Zhang, H2
Ma, J1
Tang, K1
Cheng, F1
Zhang, C1
Dong, B1
Zhao, Y1
Yuan, P1
Gao, Q1
Xiao-Feng Qin, F1
Huang, B1
PEART, WS1
PORTER, KA1
ROBERTSON, JI1
SANDLER, M2
BALDOCK, E1
CAMPBELL, AC1
GOWENLOCK, AH1
PLATT, DS1
SNOW, PJ1
HALE, JF1
LANE-MITCHELL, W1
SJOERDSMA, A1
MELMON, KL1
SCHEUER, PJ1
WAT, PJ1
Long, GG1
Clemmons, RM1
Heath, H1
Eriksson, B1
Bergström, M1
Lilja, A1
Ahlström, H1
Långström, B1
Oberg, K1
Baguley, BC1
Bousquet, B1
Dreux, C1
Girard, ML1
Lipsett, MB1
Wyss, F1
Studer, H1
Staub, JJ1
Bhattacharya, SK1
Sealy, WC1
Hosoda, S1
Glick, D1
DeLellis, RA1

Reviews

3 reviews available for 5-hydroxytryptophan and Neoplasms

ArticleYear
Small-molecule cytokine inducers causing tumor necrosis.
    Current opinion in investigational drugs (London, England : 2000), 2001, Volume: 2, Issue:7

    Topics: 5-Hydroxytryptophan; Animals; Antineoplastic Agents; Capillary Permeability; Cytokines; Endothelium,

2001
[Ectopic hormone synthesis].
    Der Internist, 1971, Volume: 12, Issue:5

    Topics: 5-Hydroxytryptophan; Adrenocorticotropic Hormone; Chorionic Gonadotropin; Gastrins; Hormones, Ectopi

1971
Paraneoplastic syndromes resulting from elaboration of ectopic hormones, antigens and bizarre toxins.
    Current problems in surgery, 1972

    Topics: 5-Hydroxytryptophan; Acanthosis Nigricans; Carcinoid Tumor; Carotid Body Tumor; Catecholamines; Cush

1972

Trials

1 trial available for 5-hydroxytryptophan and Neoplasms

ArticleYear
Positron emission tomography (PET) in neuroendocrine gastrointestinal tumors.
    Acta oncologica (Stockholm, Sweden), 1993, Volume: 32, Issue:2

    Topics: 5-Hydroxytryptophan; Adenoma, Islet Cell; Carbon Radioisotopes; Carcinoid Tumor; Female; Gastrointes

1993

Other Studies

11 other studies available for 5-hydroxytryptophan and Neoplasms

ArticleYear
IL-2 regulates tumor-reactive CD8
    Nature immunology, 2021, Volume: 22, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Antibodies, Neutralizing; Antineoplastic Agents; Basic Helix-Loop-Heli

2021
Carcinoid syndrome due to pancreatic-duct neoplasm secreting 5-hydroxytryptophan and 5-hydroxytryptamine.
    Lancet (London, England), 1963, Feb-02, Volume: 1, Issue:7275

    Topics: 5-Hydroxytryptophan; Humans; Malignant Carcinoid Syndrome; Neoplasms; Pancreatic Neoplasms; Serotoni

1963
A beta-hydroxytryptophan-secreting carcinoid tumour.
    Gut, 1963, Volume: 4

    Topics: 5-Hydroxytryptophan; Carcinoid Tumor; Histamine; Humans; Malignant Carcinoid Syndrome; Neoplasms; Se

1963
THE CARCINOID SYNDROME. CASE REPORT AND REVIEW.
    The Central African journal of medicine, 1964, Volume: 10

    Topics: 5-Hydroxytryptophan; Antineoplastic Agents; Appendectomy; Drug Therapy; Humans; Liver Neoplasms; Mal

1964
THE CARCINOID SPECTRUM.
    Gastroenterology, 1964, Volume: 47

    Topics: 5-Hydroxytryptophan; Angiotensins; Antineoplastic Agents; Bronchial Neoplasms; Carcinoid Tumor; Chlo

1964
5-Hydroxytryptophan-secreting bronchial carcinoid tumour.
    Lancet (London, England), 1961, Nov-11, Volume: 2, Issue:7211

    Topics: 5-Hydroxytryptophan; Bronchi; Bronchial Neoplasms; Malignant Carcinoid Syndrome; Neoplasms; Tryptoph

1961
Metastatic canine medullary thyroid carcinoma: a case report.
    Veterinary pathology, 1980, Volume: 17, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Calcitonin; Carcinoma; Dog Diseases; Dogs; Endocrine System Diseases;

1980
[The importance of determining 5-hydroxytryptophan and hydroxyindoles in biological fluids in cancer cases].
    Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles, 1975, Feb-24, Volume: 280, Issue:8

    Topics: 5-Hydroxytryptophan; Body Fluids; Chromatography, Ion Exchange; Humans; Hydroxyindoleacetic Acid; Ne

1975
Humoral syndromes associated with cancer.
    Cancer research, 1965, Volume: 25, Issue:7

    Topics: 5-Hydroxytryptophan; Carcinoid Tumor; Carcinoma, Hepatocellular; Carotid Body Tumor; Catecholamines;

1965
Studies in histochemistry. LXXIX. Properties of tryptophan hydroxylase from neoplastic murine mast cells.
    The Journal of biological chemistry, 1966, Jan-10, Volume: 241, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Autoradiography; Hydrogen-Ion Concentration; In Vitro Techniques; Kine

1966
Formaldehyde-induced fluorescence technique for the demonstration of biogenic amines in diagnostic histopathology.
    Cancer, 1971, Volume: 28, Issue:6

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Amines; Biogenic Amines; Carcinoma; Catecholamines; Child; C

1971