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5-hydroxytryptophan and Myoclonic Jerk

5-hydroxytryptophan has been researched along with Myoclonic Jerk in 120 studies

5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.

Research Excerpts

ExcerptRelevanceReference
"A 14-year-old Saudi boy with cherry red spot-myoclonus syndrome and documented neuraminidase deficiency responded well to titrated doses of 5-hydroxytryptophan as an add-on treatment."7.67Successful treatment of cherry red spot-myoclonus syndrome with 5-hydroxytryptophan. ( Daif, AK; Gascon, G; Ozand, P; Wallenberg, B, 1988)
"In male Swiss mice, muscimol produced myoclonic jerks."7.66Serotonergic drugs, benzodiazepines and baclofen block muscimol-induced myoclonic jerks in a strain of mice. ( Menon, MK; Vivonia, CA, 1981)
" L-5-hydroxytryptophan plus carbidopa was administered to eight patients with this disorder or other syndromes in which myoclonus is prominent."7.65L-5-hydroxytryptophan in treatment of several different syndromes in which myoclonus is prominent. ( Growdon, JH; Shahani, BT; Young, RR, 1976)
" Coadministration of harmaline (but not harmine) and 5-hydroxytryptophan (tryptamine or m-chlorophenyl-piperazine) induced a lethal convulsive myoclonic syndrome which could not be evoked by either drug separately."3.67Harmala alkaloids and related beta-carbolines: a myoclonic model and antimyoclonic drugs. ( Pranzatelli, MR; Snodgrass, SR, 1987)
"This study evaluated the behavioral elements of three 5-HT-related syndromes (intraperitoneal 5-hydroxytryptophan after intracisternal 5,7-dihydroxytryptamine (DHT), p-chloroamphetamine (PCA), fenfluramine (FF), or combinations of drugs) scored from video-tapes and their relationship to locomotor activity (LMA) photocell recording, regional monoamine concentration and S-1 receptor binding."3.67Serotonin-lesion myoclonic syndromes. II. Analysis of individual syndrome elements, locomotor activity and behavioral correlations. ( Pranzatelli, MR; Snodgrass, SR, 1986)
"A 14-year-old Saudi boy with cherry red spot-myoclonus syndrome and documented neuraminidase deficiency responded well to titrated doses of 5-hydroxytryptophan as an add-on treatment."3.67Successful treatment of cherry red spot-myoclonus syndrome with 5-hydroxytryptophan. ( Daif, AK; Gascon, G; Ozand, P; Wallenberg, B, 1988)
"In male Swiss mice, muscimol produced myoclonic jerks."3.66Serotonergic drugs, benzodiazepines and baclofen block muscimol-induced myoclonic jerks in a strain of mice. ( Menon, MK; Vivonia, CA, 1981)
"A myoclonic syndrome consisting of tremor, myoclonus, and seizures was produced following the systemic administration of 5-hydroxytryptophan to adult rats previously given intracisternal injections of 5,7-dihydroxytryptamine and systemic desmethylimipramine, but not in their controls."3.65Myoclonus after 5-hydroxytryptophan in rats with lesions of indoleamine neurons in the central nervous system. ( Baldessarini, RJ; Cancian, D; Growdon, JH; Stewart, RM, 1976)
"Three patients with postanoxic intention myoclonus, two patients with intention tremor, and one patient with cerebral palsy were administered L-5-hydroxytryptophan (L-5HTP), the precursor of serotonin, in combination with MK 486, a peripheral amino acid decarboxylase inhibitor."3.65Therapy of intention myoclonus with L-5-hydroxytryptophan and a peripheral decarboxylase inhibitor, MK 486. ( Sethy, VH; Van Woert, MH, 1975)
" L-5-hydroxytryptophan plus carbidopa was administered to eight patients with this disorder or other syndromes in which myoclonus is prominent."3.65L-5-hydroxytryptophan in treatment of several different syndromes in which myoclonus is prominent. ( Growdon, JH; Shahani, BT; Young, RR, 1976)
"In 6 patients with intention myoclonus, the cerebrospinal fluid concentration of 5-hydroxyindoleacetic acid, a metabolite of serotonin was found to be significantly decreased."2.64Serotonin and myoclonus. ( Bowers, MB; Jutkowitz, R; Rosenbaum, D; Van Woert, MH, 1976)
"So-called symptomatic myoclonus is the type that occurs secondary to an identifiable disorder; it is usually accompanied by other neurological signs and is the most frequent kind."2.45[Myoclonic spasms: their clinical and neurophysiological characteristics, aetiology and treatment]. ( Erro, ME; Navarro, MC, 2009)
"Epileptic myoclonus is that which forms part of an epileptic syndrome with a genetic or idiopathic cause, or that is due to static encephalopathy."2.45[Myoclonic spasms: their clinical and neurophysiological characteristics, aetiology and treatment]. ( Erro, ME; Navarro, MC, 2009)
"The literature on myoclonus and serotonin neuropharmacology reveals evidence for serotonergic abnormalities in some human myoclonic disorders, new serotonin receptor subtypes and data on their molecular structure and function, more selective drugs, and experimental evidence linking certain serotonin receptor subtypes with myoclonus."2.39Serotonin and human myoclonus. Rationale for the use of serotonin receptor agonists and antagonists. ( Pranzatelli, MR, 1994)
"Clonazepam is a potent anticonvulsant 1,4-benzodiazepine that controls some types of myoclonus."2.37Mechanism of action of clonazepam in myoclonus in relation to effects on GABA and 5-HT. ( Jenner, P; Marsden, CD; Pratt, JA, 1986)
"MDL100."1.30Head and whole-body jerking in guinea pigs are differentially modulated by 5-HT1A, 5-HT1B/1D and 5-HT2A receptor antagonists. ( Nielsen, CK, 1998)
"Myoclonus was induced by the 5-HT precursor L-5-hydroxytryptophan (L-5-HTP) and the non-selective 5-HT1A/1B/5-HT2 receptor agonist 5-methoxy-N,N-dimethyl-tryptamine (5-MeODMT)."1.30Head and whole-body jerking in guinea pigs are differentially modulated by 5-HT1A, 5-HT1B/1D and 5-HT2A receptor antagonists. ( Nielsen, CK, 1998)
"We studied 6 patients with myoclonus elicited by flash stimulation (1-15 Hz)."1.29The pathophysiology and pharmacology of photic cortical reflex myoclonus. ( Artieda, J; Obeso, JA, 1993)
"The data suggest that this rat cardiac arrest model may be a valuable tool for investigating the pathophysiologic mechanisms of posthypoxic myoclonus and for developing new therapeutic strategies for treating the disorder."1.29Novel rat cardiac arrest model of posthypoxic myoclonus. ( Hussong, MJ; Matsumoto, RR; Schwartz, PH; Truong, DD; Wasterlain, CG, 1994)
"The auditory-induced myoclonus continues to worsen, reaches a peak about 2 weeks after the arrest, then declines over time to subnormal levels."1.29Novel rat cardiac arrest model of posthypoxic myoclonus. ( Hussong, MJ; Matsumoto, RR; Schwartz, PH; Truong, DD; Wasterlain, CG, 1994)
"Body weight was reduced both in rats with early and late 5,7-DHT lesions, but reduction persisted in rats with early lesions."1.28Intracisternal 5,7-dihydroxytryptamine lesions in neonatal and adult rats: comparison of response to 5-hydroxytryptophan. ( Dollison, AM; Hlibczuk, V; Pranzatelli, MR, 1989)
"Pretreatment with 5-hydroxytryptophan (5-HTP), a precursor of 5-HT, antagonised while pretreatment with p-chlorophenylalanine (PCPA), a 5-HT depletor, potentiated the myoclonus induced by picrotoxin, a GABA antagonist."1.28A functional interaction between GABA and 5-HT in inhibiting picrotoxin-induced myoclonus in rats. ( Krishnamoorthy, MS; Paul, V, 1990)
"Pretreatment with aminooxyacetic acid (AOAA), a GABA transaminase inhibitor, antagonised picrotoxin-induced myoclonus."1.28A functional interaction between GABA and 5-HT in inhibiting picrotoxin-induced myoclonus in rats. ( Krishnamoorthy, MS; Paul, V, 1990)
"Ro 15-1788 completely blocked type B myoclonus without decreasing the level of vigilance in the two types of baboons, and reversed the antiepileptic action of the BZs in the photosensitive ones, permitting the reappearance of myoclonus following EEG paroxysmal discharges (type A)."1.27Differential effects of the benzodiazepine antagonist Ro 15-1788 on two types of myoclonus in baboon Papio papio. ( Bryere, P; Kaijima, M; Naquet, R; Valin, A, 1983)
"From a family with essential familial myoclonus, 150 members in eight generations were studied."1.27Essential familial myoclonus. ( Muhr, H; Przuntek, H, 1983)
"A patient with long-standing intention myoclonus was treated with oral clonazepam, which resulted in clinical and electrophysiologic improvement as manifested by dramatic reduction in intention myoclonus and diminished amplitude of somatosensory evoked potentials after treatment."1.27Posttraumatic intention myoclonus. ( Bjork, RJ; Snyder, BD; Starosta-Rubinstein, S; Tulloch, JW, 1983)
"This treatment produced also myoclonus and increased the time spent resting during trials."1.27Effects of the chronic ingestion of therapeutic doses of chlorimipramine on the behavioral action of agonists and antagonists of serotonin in male rats. ( Broitman, ST; Fóscolo, MR; Rodríguez Echandía, EL, 1983)
"L-5-hydroxytryptophan (L-5-HTP)-induced myoclonus was used as a behavioral index of central serotonergic activity."1.27Estradiol and progesterone influence a serotonin mediated behavioral syndrome (myoclonus) in female guinea pigs: comparison with steroid effects on reproductive behavior. ( Feder, HH; O'Connor, LH, 1984)
"Indoleamine-induced myoclonus in guinea pigs is a specific model of brainstem 5-HT function that can be used to characterize the indoleamine systems initiating myoclonus."1.275-HT-mediated myoclonus in the guinea pig as a model of brainstem 5-HT and tryptamine receptor action. ( Jenner, P; Luscombe, G; Marsden, CD, 1986)
"p,p'-DDT-induced myoclonus in mice has been proposed as a model of stimulus-sensitive action myoclonus responsive to L-5-HTP and clonazepam treatment."1.27p,p'-DDT-induced myoclonus in the rat and its application as an animal model of 5-HT-sensitive action myoclonus. ( Jenner, P; Marsden, CD; Pratt, JA; Rothwell, J, 1986)
"Posthypoxic action myoclonus is usually associated with impaired serotonin (5-HT) neurotransmission but in some patients 5-HT precursors aggravate and 5-HT blockers improve action myoclonus."1.27Clinical, biochemical, and pharmacological observation in a patient with postasphyxic myoclonus: association to serotonin hyperactivity. ( De Yebenes, JG; Giménez-Roldán, S; Mateo, D; Muradas, V, 1988)
"Some types of intention myoclonus respond to serotonin precursor therapy (e."1.27Fluoxetine in the treatment of intention myoclonus. ( Chung, E; Magnussen, I; Rosenbaum, D; Van Woert, MH, 1983)
"Abnormal movements (myoclonus, lateral head weaving) of the myoclonic syndromes were better antagonized than postural abnormalities (hindlimb abduction, hunching of back)."1.27Antimyoclonic properties of S2 serotonin receptor antagonists in the rat. ( Pranzatelli, MR; Snodgrass, SR, 1986)
"This chapter concerns palatal myoclonus."1.27Palatal myoclonus. ( Lapresle, J, 1986)
"Multiple forms of myoclonus (appendicular and truncal) and convulsions were dose-dependent drug effects."1.27Serotonin-lesion myoclonic syndromes. II. Analysis of individual syndrome elements, locomotor activity and behavioral correlations. ( Pranzatelli, MR; Snodgrass, SR, 1986)
"The neurochemical basis of myoclonus responding to 5HT precursors and clonazepam is discussed."1.26Clinical, biochemical, and physiological features distinguishing myoclonus responsive to 5-hydroxytryptophan, tryptophan with a monoamine oxidase inhibitor, and clonazepam. ( Chadwick, D; Hallett, M; Harris, R; Jenner, P; Marsden, CD; Reynolds, EH, 1977)
"Such myoclonus may be induced also by the administration of L-tryptophan plus a monamine oxidase inhibitor (MAOI), or by agents acting as serotonin (5-HT) receptor agonists."1.265-hydroxytryptophan-induced myoclonus in guinea pigs. A physiological and pharmacological investigations. ( Chadwick, D; Hallett, M; Jenner, P; Marsden, CD, 1978)
"Post-hypoxic intention myoclonus successfully treated by long-term administration of the combination of 5-hydroxytryptophan and carbidopa is described."1.26Post-hypoxic intention myoclonus treated with 5-hydroxy-tryptophan and an extracerebral decarboxylase inhibitor. ( de Fine Olivarius, B; Dupont, E; Engbaek, F; Magnussen, I, 1978)
"It is suggested that myoclonus induced by tryptamine in guinea pigs pretreated with pargyline involves activation of post-synaptic indoleamine receptors by tryptamine by a mechanism which requires intact presynaptic function of 5HT."1.26Tryptamine-induced myoclonus in guinea-pigs pretreated with a monoamine oxidase inhibitor indicates pre- and post-synaptic actions of tryptamine upon central indoleamine systems. ( Jenner, P; Luscombe, G; Marsden, CD, 1982)
"In two patients with postanoxic action myoclonus, L-tryptophan or a monoamine oxidase inhibitor induced a moderate improvement, but L-5-hydroxytryptophan had greater therapeutic effect."1.26Beneficial effects of serotonin precursors in postanoxic action myoclonus. ( De Léan, J; Hornykiewicz, O; Richardson, JC, 1976)
"A patient with post-hypoxic myoclonus, sensitive to therapy with 5-hydroxytryptophan and clonazepam, was subjected to detailed electrophysiological investigation."1.26Reticular reflex myoclonus: a physiological type of human post-hypoxic myoclonus. ( Adam, J; Chadwick, D; Hallett, M; Marsden, CD, 1977)
"Postanoxic myoclonus was first accepted as being related to a dysfunction of the ventrolateral thalamic nucleus."1.26Postanoxic myoclonus. Treatment of a case with 5-hydroxytryptophane and a decarboxylase inhibitor. ( Beretta, E; de Crousaz, G; Regli, F; Steck, AJ, 1981)
"The bioavailability of orally administered L-5-hydroxytryptophan in steady state was investigated at four increasing multiple dose levels in five patients suffering from various myoclonic disorders."1.26Bioavailability and related pharmacokinetics in man of orally administered L-5-hydroxytryptophan in steady state. ( Magnussen, I; Nielsen-Kudsk, F, 1980)
" The finding of a direct proportionality between the size of the oral dose level of L-5-hydroxytryptophan and the corresponding areas under the plasma concentration curves within a dosage interval at steady state strongly indicates dose independent, linear pharmacokinetics of the compound."1.26Bioavailability and related pharmacokinetics in man of orally administered L-5-hydroxytryptophan in steady state. ( Magnussen, I; Nielsen-Kudsk, F, 1980)
"p,p'-DDT-treated rats had increased concentrations of 5-hydroxyindoleacetic acid (5-HIAA) in seven regional areas, but serotonin was increased only in the midbrain and cerebellum."1.26p,p'-DDT-induced neurotoxic syndrome: experimental myoclonus. ( Hwang, EC; Van Woert, MH, 1978)
"Myoclonus was induced in guinea pigs in a dose-dependent manner by intraperitoneal injection of L-5-hydroxytryptophan (L-5-HTP)."1.26Functional anatomy of L-5-hydroxytryptophan-induced myoclonus in the guinea pig. ( Thal, LJ; Wolfson, LI, 1981)
" At a dosage of 400 mg per kilogram, all animals developed myoclonus."1.26Functional anatomy of L-5-hydroxytryptophan-induced myoclonus in the guinea pig. ( Thal, LJ; Wolfson, LI, 1981)
"We postulate that p,p'-DDT-induced myoclonus may be causally related to blockage of serotonin receptors or inhibition of serotonin release into the synapse, resulting in functional deficiency of this neurotransmiter at the receptor site."1.26p,p'-DDT-induced neurotoxic syndrome: experimental myoclonus. ( Hwang, EC; Van Woert, MH, 1978)
"In 18 patients with intention myoclonus due to anoxia or other brain damage, 11 derived more than 50% overall improvement during treatment with L-5HTP and carbidopa."1.26Long-term therapy of myoclonus and other neurologic disorders with L-5-hydroxytryptophan and carbidopa. ( Bowers, MB; Howieson, J; Rosenbaum, D; Van Woert, MH, 1977)
"Six patients with myoclonus of varying cause were treated with L-5-hydroxytryptophan (L-5-HTP) and carbidopa."1.26Treatment of myoclonus with L-5-hydroxytryptophan and carbidopa: clinical, electrophysiological, and biochemical observations. ( Katzman, R; Sharpless, NS; Thal, LJ; Wolfson, L, 1980)
"Progress in the treatment of action myoclonus is especially noteworthy and has led to the implication of serotonin deficit in the pathophysiology of this syndrome."1.26New approaches in the management of hyperkinetic movement disorders. ( Fahn, S, 1977)
"Three patients with postanoxic intention myoclonus, two patients with intention tremor, and one patient with cerebral palsy were administered L-5-hydroxytryptophan (L-5HTP), the precursor of serotonin, in combination with MK 486, a peripheral amino acid decarboxylase inhibitor."1.25Therapy of intention myoclonus with L-5-hydroxytryptophan and a peripheral decarboxylase inhibitor, MK 486. ( Sethy, VH; Van Woert, MH, 1975)
"The response of myoclonus to oral and intravenous L-5-hydroxytryptophan (5-H."1.25Manipulation of brain serotonin in the treatment of myoclonus. ( Chadwick, D; Harris, R; Jenner, P; Marsden, CD; Reynolds, EH, 1975)
"Levodopa-induced myoclonus may be related to intermittent increases of activity of serotonin in the brain and results from levodopa-induced dysregulation of serotonin activity."1.25Levodopa-induced myoclonus. ( Bergen, D; Goetz, C; Klawans, HL, 1975)
" Although directly related to daily dosage of levodopa, the myoclonus was specifically blocked by the serotonin antagonist, methysergide."1.25Levodopa-induced myoclonus. ( Bergen, D; Goetz, C; Klawans, HL, 1975)

Research

Studies (120)

TimeframeStudies, this research(%)All Research%
pre-1990108 (90.00)18.7374
1990's10 (8.33)18.2507
2000's2 (1.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Erro, ME1
Navarro, MC1
Menon, MK1
Vivonia, CA1
Luscombe, G3
Jenner, P10
Marsden, CD14
Valin, A1
Kaijima, M1
Bryere, P1
Naquet, R1
Beretta, E1
Regli, F2
de Crousaz, G1
Steck, AJ1
Van Woert, MH14
Magnussen, I8
Lowe, YH1
Hwang, EC3
Rosenbaum, D5
Chung, E1
Przuntek, H1
Muhr, H1
Mondrup, K1
Engbaek, F2
Lademann, A1
Olivarius, BD1
Feit, H1
Kirkpatrick, J1
Pandian, G1
Starosta-Rubinstein, S1
Bjork, RJ1
Snyder, BD1
Tulloch, JW1
Meyers, AS1
Rodríguez Echandía, EL1
Broitman, ST1
Fóscolo, MR1
Sunohara, N1
Mukoyama, M1
Mano, Y1
Satoyoshi, E2
O'Connor, LH3
Feder, HH2
Nielsen-Kudsk, F1
Thal, LJ3
Sharpless, NS1
Wolfson, L2
Katzman, R2
Wolfson, LI2
Avanzini, G2
Bossi, L1
Caraceni, T1
Consolazione, A1
Franceschetti, S2
Negri, S1
Parati, E1
Nausieda, PA4
Carvey, PM4
Weiner, WJ5
Lombardi, B1
Passerini, A1
Braun, A1
Sternberg, EM1
Young, SN1
Baker, H1
Gauthier, S1
Osterland, CK1
Pranzatelli, MR10
Matsumoto, RR2
Aziz, N1
Truong, DD2
Artieda, J1
Obeso, JA1
Schwartz, PH1
Hussong, MJ1
Wasterlain, CG1
Galvan, I1
Tailor, PT1
Nielsen, CK1
Frucht, SJ1
Klawans, HL10
Trimble, M1
Chadwick, D8
Reynolds, EH4
Harris, R2
DeLéan, J1
Richardson, JC3
Stewart, RM4
Campbell, A2
Sperk, G2
Baldessarini, RJ4
Levin, SL1
Munsat, TL1
Dupont, E2
Prange-Hansen, A1
de Fine Olivarius, B2
Hallett, M4
Adam, J1
Hallet, M1
Goetz, C5
Fahn, S1
Gerson, SC1
Growdon, JH4
Volkman, PH1
Lorens, SA1
Kindel, GH1
Ginos, JZ1
Carroll, WM1
Walsh, PJ1
Howieson, J1
Bowers, MB2
Jutkowitz, R1
Sethy, VH2
Bergen, D1
Lhermitte, F2
Degos, CF1
Marteau, R2
Chazot, G1
Guard, O1
Setiey, A1
Robert, JM1
Schott, B1
D'Amico, DJ1
Patel, BC1
Cancian, D2
De Léan, J2
Hornykiewicz, O2
Young, RR1
Shahani, BT1
Kinoshita, M1
Takazawa, Y1
Yoda, K1
Thal, L1
Sharpless, N1
Engel, J1
Jiménez-Jiménez, FJ1
Roldan, A1
Zancada, F1
Molina-Arjona, JA1
Fernandez-Ballesteros, A1
Santos, J1
Paul, V2
Krishnamoorthy, MS2
Bhatt, M1
Snow, B1
Varelas, M1
Calne, D1
Nakano, K1
Hayakawa, T1
Shishikura, K1
Ohsawa, M1
Suzuki, H1
Fukuyama, Y1
Chung, EY2
Rewcastle, NB1
Pratt, JA2
Rothwell, J1
Giménez-Roldán, S1
Mateo, D1
Muradas, V1
De Yebenes, JG1
Dollison, AM1
Hlibczuk, V1
Snodgrass, SR6
Uldry, PA1
Gobbi, G1
Melideo, G1
Giovanardi Rossi, P1
Chapman, AG1
Bo, P2
Camana, C1
Curti, M1
Fussi, F1
Giorgetti, A1
Savoldi, F2
Gascon, G1
Wallenberg, B1
Daif, AK1
Ozand, P1
Lapresle, J1
Tanner, CM1
Goetz, CG3
Carvey, P1
Paulseth, JE1
Brown, LL1
Rubin, G1
Patrucco, M1
Lieberman, JA2
Kane, JM2
Reife, R2
Fischette, CT1
Fischer-Perroudon, C1
Mouret, J1
Jouvet, M1
Rohmer, F1
Warter, JM1
Coquillat, G1
Maitrot, D1
Kurtz, D1
Micheletti, G1
Mack, G1
Mandel, P1
Westheimer, R1
Guilleminault, C1
Tharp, BR1
Cousin, D1
Sabouraud, O1
Chatel, M1
Badiche, A1
Chauvel, P1
Le Clec'h, G1
Clineschmidt, BV1
Lotti, VJ1
Bieger, D1
Larochelle, L1
Peterfalvi, M1
Gazengel, J1
Serdaru, M1

Reviews

9 reviews available for 5-hydroxytryptophan and Myoclonic Jerk

ArticleYear
[Myoclonic spasms: their clinical and neurophysiological characteristics, aetiology and treatment].
    Revista de neurologia, 2009, Jan-23, Volume: 48 Suppl 1

    Topics: 5-Hydroxytryptophan; Anticonvulsants; Antidepressive Agents, Second-Generation; Diagnosis, Different

2009
Serotonin and human myoclonus. Rationale for the use of serotonin receptor agonists and antagonists.
    Archives of neurology, 1994, Volume: 51, Issue:6

    Topics: 5-Hydroxytryptophan; Brain; Humans; Hydroxyindoleacetic Acid; Myoclonus; Receptors, Serotonin; Serot

1994
Myoclonus.
    Modern trends in neurology, 1975, Volume: 6

    Topics: 5-Hydroxytryptophan; Humans; Myoclonus; Serotonin

1975
Mechanism of action of clonazepam in myoclonus in relation to effects on GABA and 5-HT.
    Advances in neurology, 1986, Volume: 43

    Topics: 5-Hydroxytryptophan; Animals; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Brain; Clonazepam

1986
[Indications for L-5-hydroxytryptophan in neurology].
    Revue medicale de la Suisse romande, 1987, Volume: 107, Issue:9

    Topics: 5-Hydroxytryptophan; Down Syndrome; Epilepsy; Humans; Migraine Disorders; Myoclonus; Pain; Parkinson

1987
The pharmacology of myoclonus.
    Clinical neuropharmacology, 1985, Volume: 8, Issue:2

    Topics: 5-Hydroxytryptophan; Adrenocorticotropic Hormone; Animals; Anticonvulsants; Benzodiazepines; Brain;

1985
Valproate and myoclonus.
    Advances in neurology, 1986, Volume: 43

    Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Aspartic Acid; Clonazepam; DDT; Disease Models, Animal; F

1986
Neuromuscular effects of monoamine oxidase inhibitors.
    Advances in neurology, 1986, Volume: 43

    Topics: 5-Hydroxytryptophan; Adult; Animals; Clomipramine; Clorgyline; Depressive Disorder; Female; Humans;

1986
Hormone effects on serotonin-dependent behaviors.
    Annals of the New York Academy of Sciences, 1986, Volume: 474

    Topics: 5-Hydroxytryptophan; Androgens; Animals; Behavior, Animal; Estrogens; Female; Guinea Pigs; Male; Myo

1986

Trials

4 trials available for 5-hydroxytryptophan and Myoclonic Jerk

ArticleYear
Myoclonus and L-5-hydroxytryptophan (L-5HTP).
    Progress in clinical and biological research, 1983, Volume: 127

    Topics: 5-Hydroxytryptophan; Carbidopa; Clinical Trials as Topic; Drug Industry; Drug Therapy, Combination;

1983
Development of a scleroderma-like illness during therapy with L-5-hydroxytryptophan and carbidopa.
    The New England journal of medicine, 1980, Oct-02, Volume: 303, Issue:14

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Carbidopa; Clinical Trials as Topic; Drug Therapy, Com

1980
Serotonin and myoclonus.
    Monographs in neural sciences, 1976, Volume: 3

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Carbidopa; Clinical Trials as Topic; Epilepsy; Female; Homov

1976
[Pharmacological and biochemical approach to a syndrome of action and intention myoclonus in the course of degenerative disease of the nervous system].
    Revue neurologique, 1973, Volume: 128, Issue:5

    Topics: 5-Hydroxytryptophan; Adult; Benzazepines; Cerebellar Ataxia; Clinical Trials as Topic; Diagnosis, Di

1973

Other Studies

107 other studies available for 5-hydroxytryptophan and Myoclonic Jerk

ArticleYear
Serotonergic drugs, benzodiazepines and baclofen block muscimol-induced myoclonic jerks in a strain of mice.
    European journal of pharmacology, 1981, Jul-17, Volume: 73, Issue:2-3

    Topics: 5-Hydroxytryptophan; Animals; Anti-Anxiety Agents; Baclofen; Benzodiazepines; Male; Mice; Muscimol;

1981
Tryptamine-induced myoclonus in guinea-pigs pretreated with a monoamine oxidase inhibitor indicates pre- and post-synaptic actions of tryptamine upon central indoleamine systems.
    Neuropharmacology, 1982, Volume: 21, Issue:12

    Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Female; Guinea Pigs; Monoamine Oxidase Inhibitors; M

1982
Differential effects of the benzodiazepine antagonist Ro 15-1788 on two types of myoclonus in baboon Papio papio.
    Neuroscience letters, 1983, Jul-15, Volume: 38, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepinones; Flumazenil; g

1983
Postanoxic myoclonus. Treatment of a case with 5-hydroxytryptophane and a decarboxylase inhibitor.
    Journal of neurology, 1981, Volume: 225, Issue:1

    Topics: 5-Hydroxytryptophan; Benserazide; Humans; Hydrazines; Hydroxyindoleacetic Acid; Hypoxia; Male; Middl

1981
Study of serotonin in neuropsychiatric disorders.
    The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 1982, Volume: 30, Issue:8

    Topics: 5-Hydroxytryptophan; Carbidopa; Female; Homovanillic Acid; Humans; Hydroxyindoleacetic Acid; Kinetic

1982
Fluoxetine in the treatment of intention myoclonus.
    Clinical neuropharmacology, 1983, Volume: 6, Issue:1

    Topics: 5-Hydroxytryptophan; Adult; Blood Platelets; Carbidopa; Female; Fluoxetine; Humans; Hydroxyindoleace

1983
Alterations in brain 5HT and tryptamine content during indoleamine-induced myoclonus in guinea pigs.
    Biochemical pharmacology, 1983, Jun-15, Volume: 32, Issue:12

    Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Brain; Carbidopa; Drug Interactions; Female; Guinea

1983
Essential familial myoclonus.
    Journal of neurology, 1983, Volume: 230, Issue:3

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Child; Female; Germany, West; Humans; Male; Middle Age

1983
Treatment of myoclonic syndromes with paroxetine alone or combined with 5-HTP.
    Acta neurologica Scandinavica, 1982, Volume: 66, Issue:2

    Topics: 5-Hydroxytryptophan; Adult; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Myoclonus;

1982
Myoclonus, ataxia, and hypoventilation: response to L-5-hydroxytryptophan.
    Neurology, 1983, Volume: 33, Issue:1

    Topics: 5-Hydroxytryptophan; Adult; Ataxia; Female; Humans; Hypoventilation; Mitochondria, Muscle; Myoclonus

1983
Posttraumatic intention myoclonus.
    Surgical neurology, 1983, Volume: 20, Issue:2

    Topics: 5-Hydroxytryptophan; Benzodiazepinones; Brain Damage, Chronic; Clonazepam; Evoked Potentials, Somato

1983
Orphan drugs and orphan diseases: the consumer's viewpoint.
    Progress in clinical and biological research, 1983, Volume: 127

    Topics: 5-Hydroxytryptophan; Drug Industry; Humans; Legislation, Drug; Myoclonus; Tourette Syndrome; United

1983
L-5 HTP available under treatment IND.
    FDA drug bulletin, 1983, Volume: 13, Issue:2

    Topics: 5-Hydroxytryptophan; Humans; Myoclonus; Professional Staff Committees; United States; United States

1983
Effects of the chronic ingestion of therapeutic doses of chlorimipramine on the behavioral action of agonists and antagonists of serotonin in male rats.
    Pharmacology, biochemistry, and behavior, 1983, Volume: 19, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Clomipramine; Exploratory Behavior; Fluoxetine; Male; Methysergide; Mo

1983
Action-induced rhythmic dystonia: an autopsy case.
    Neurology, 1984, Volume: 34, Issue:3

    Topics: 5-Hydroxytryptophan; Cerebral Infarction; Clonazepam; Dystonia; Electroencephalography; Electromyogr

1984
Estradiol and progesterone influence a serotonin mediated behavioral syndrome (myoclonus) in female guinea pigs: comparison with steroid effects on reproductive behavior.
    Brain research, 1984, Feb-13, Volume: 293, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Drug Interactions; Estradiol; Female; Guinea Pigs; Models, Neurologica

1984
From the NIH: New treatment for myoclonus patients.
    JAMA, 1980, May-02, Volume: 243, Issue:17

    Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Depression, Chemical; Humans; Myoclonus; Serotonin

1980
Bioavailability and related pharmacokinetics in man of orally administered L-5-hydroxytryptophan in steady state.
    Acta pharmacologica et toxicologica, 1980, Volume: 46, Issue:4

    Topics: 5-Hydroxytryptophan; Administration, Oral; Adult; Biological Availability; Carbidopa; Dose-Response

1980
Treatment of myoclonus with L-5-hydroxytryptophan and carbidopa: clinical, electrophysiological, and biochemical observations.
    Annals of neurology, 1980, Volume: 7, Issue:6

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Carbidopa; Clonazepam; Diarrhea; Drug Therapy, Combination;

1980
Functional anatomy of L-5-hydroxytryptophan-induced myoclonus in the guinea pig.
    Neurology, 1981, Volume: 31, Issue:8

    Topics: 5-Hydroxytryptophan; Animals; Autoradiography; Brain; Cerebral Cortex; Densitometry; Dose-Response R

1981
Effect of L-5HTP and drugs acting on serotonin metabolism in various myoclonic syndromes.
    Monographs in neural sciences, 1980, Volume: 5

    Topics: 5-Hydroxytryptophan; Brain Chemistry; Clonazepam; Humans; Myoclonic Cerebellar Dyssynergia; Myoclonu

1980
Modification of central serotonergic and dopaminergic behaviors in the course of chronic corticosteroid administration.
    European journal of pharmacology, 1982, Mar-12, Volume: 78, Issue:3

    Topics: 5-Hydroxytryptophan; Adrenal Cortex Hormones; Animals; Apomorphine; Behavior, Animal; Circadian Rhyt

1982
Segmental action and stimuli-sensitive myoclonus with acute onset. A case report.
    Italian journal of neurological sciences, 1980, Volume: 1, Issue:4

    Topics: 5-Hydroxytryptophan; Acute Disease; Adult; Angiography; Carbidopa; Carotid Arteries; Cerebrovascular

1980
Long-term suppression of central serotonergic activity by corticosteroids: a possible model of steroid-responsive myoclonic disorders.
    Neurology, 1982, Volume: 32, Issue:7

    Topics: 5-Hydroxytryptophan; Adrenal Cortex Hormones; Animals; Apomorphine; Circadian Rhythm; Guinea Pigs; H

1982
Association between brain indole levels and severity of posthypoxic myoclonus in rats.
    Pharmacology, biochemistry, and behavior, 1995, Volume: 50, Issue:4

    Topics: 5-Hydroxytryptophan; Analysis of Variance; Animals; Brain; Hydroxyindoleacetic Acid; Hypoxia, Brain;

1995
The pathophysiology and pharmacology of photic cortical reflex myoclonus.
    Annals of neurology, 1993, Volume: 34, Issue:2

    Topics: 5-Hydroxytryptophan; Aged; Aged, 80 and over; Ataxia; Cerebral Cortex; Dopamine Agents; Electroencep

1993
Novel rat cardiac arrest model of posthypoxic myoclonus.
    Movement disorders : official journal of the Movement Disorder Society, 1994, Volume: 9, Issue:2

    Topics: 5-Hydroxytryptophan; Acoustic Stimulation; Animals; Anticonvulsants; Clonazepam; Disease Models, Ani

1994
Human brainstem serotonin receptors: characterization and implications for subcortical myoclonus.
    Clinical neuropharmacology, 1996, Volume: 19, Issue:6

    Topics: 5-Hydroxytryptophan; Adult; Aged; Binding, Competitive; Brain Stem; Cerebral Cortex; Female; Humans;

1996
Head and whole-body jerking in guinea pigs are differentially modulated by 5-HT1A, 5-HT1B/1D and 5-HT2A receptor antagonists.
    European journal of pharmacology, 1998, Nov-20, Volume: 361, Issue:2-3

    Topics: 5-Hydroxytryptophan; Animals; Benzazepines; Guinea Pigs; Head Movements; Male; Methoxydimethyltrypta

1998
The clinical challenge of posthypoxic myoclonus.
    Advances in neurology, 2002, Volume: 89

    Topics: 5-Hydroxytryptophan; Anticonvulsants; Clonazepam; Humans; Hypoxia; Levetiracetam; Myoclonus; Neuropr

2002
DDT-induced myoclonus: serotonin and alpha noradrenergic interaction.
    Research communications in chemical pathology and pharmacology, 1979, Volume: 23, Issue:2

    Topics: 5-Hydroxytryptophan; Adrenergic alpha-Antagonists; Animals; Brain Chemistry; DDT; Male; Mice; Myoclo

1979
Dopaminergic antagonism of L-5-hydroxytryptophan-induced myoclonic jumping behavior.
    Neurology, 1979, Volume: 29, Issue:12

    Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Dopamine Antagonists; Ergolines; Guinea Pigs; Haloperidol

1979
Letter: L 5-Hydroxytryptophan and mood.
    Lancet (London, England), 1975, Mar-08, Volume: 1, Issue:7906

    Topics: 5-Hydroxytryptophan; Affective Symptoms; Aggression; Brain Neoplasms; Depression; Dose-Response Rela

1975
Manipulation of brain serotonin in the treatment of myoclonus.
    Lancet (London, England), 1975, Sep-06, Volume: 2, Issue:7932

    Topics: 5-Hydroxytryptophan; Administration, Oral; Adult; Aged; Benzodiazepinones; Brain; Carbidopa; Clonaze

1975
Letter: Relief of myoclonus by L-tryptophan.
    Lancet (London, England), 1975, Nov-01, Volume: 2, Issue:7940

    Topics: 5-Hydroxytryptophan; Administration, Oral; Aged; Female; Humans; Male; Middle Aged; Myoclonus; Trypt

1975
Receptor mechanisms in increased sensitivity to serotonin agonists after dihydroxytryptamine shown by electronic monitoring of muscle twitches in the rat.
    Psychopharmacology, 1979, Feb-28, Volume: 60, Issue:3

    Topics: 5-Hydroxytryptophan; 5,7-Dihydroxytryptamine; Animals; Brain; Cyproheptadine; Denervation; Desiprami

1979
[Serotoninergic conception of myoclonic syndromes. (Review)].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1979, Volume: 79, Issue:6

    Topics: 5-Hydroxytryptophan; Animals; Brain; Brain Chemistry; Carbidopa; Dogs; Electroencephalography; Elect

1979
Serotonin and myoclonic seizures.
    The New England journal of medicine, 1977, Jan-13, Volume: 296, Issue:2

    Topics: 5-Hydroxytryptophan; Humans; Hypoxia, Brain; Myoclonus; Serotonin

1977
Palatal myoclonus treated with 5-hydroxytryptophan and a decarboxylase-inhibitor.
    Acta neurologica Scandinavica, 1977, Volume: 55, Issue:3

    Topics: 5-Hydroxytryptophan; Adult; Carbidopa; Drug Combinations; Humans; Hydrazines; Male; Muscle Contracti

1977
Reticular reflex myoclonus: a physiological type of human post-hypoxic myoclonus.
    Journal of neurology, neurosurgery, and psychiatry, 1977, Volume: 40, Issue:3

    Topics: 5-Hydroxytryptophan; Clonazepam; Electroencephalography; Evoked Potentials; Humans; Hypoxia; Male; M

1977
5-Hydroxytryptophan-induced behaviour in guinea-pigs: its relevance to human myoclonus [proceedings].
    British journal of clinical pharmacology, 1977, Volume: 4, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Electromyography; Guinea Pigs; Humans; Muscle Contra

1977
Clonazepam and 5-hydroxytryptophan-induced myoclonic stereotypy.
    European journal of pharmacology, 1977, Nov-01, Volume: 46, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Behavior; Benzodiazepinones; Brain Chemistry; Clonazepam; Drug Interac

1977
New approaches in the management of hyperkinetic movement disorders.
    Advances in experimental medicine and biology, 1977, Volume: 90

    Topics: 5-Hydroxytryptophan; Carbidopa; Chorea; Dyskinesia, Drug-Induced; Humans; Movement Disorders; Myoclo

1977
5-hydroxytryptophan-induced myoclonus in guinea pigs. A physiological and pharmacological investigations.
    Journal of the neurological sciences, 1978, Volume: 35, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Cyproheptadine; Electromyography; Female; Guinea Pigs; Male; Motor Act

1978
Post-hypoxic intention myoclonus treated with 5-hydroxy-tryptophan and an extracerebral decarboxylase inhibitor.
    Acta neurologica Scandinavica, 1978, Volume: 57, Issue:4

    Topics: 5-Hydroxytryptophan; Adult; Carbidopa; Drug Evaluation; Drug Therapy, Combination; Humans; Hydrazine

1978
Biochemical, behavioral, and pharmacologic studies of the effects of dihydroxytryptamines in the rodent brain.
    Annals of the New York Academy of Sciences, 1978, Jun-12, Volume: 305

    Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Brain; Dihydroxytryptamines; Male; Mice; Myoclonus;

1978
Changes in motor behavior following the administration of serotonin neurotoxins.
    Annals of the New York Academy of Sciences, 1978, Jun-12, Volume: 305

    Topics: 5-Hydroxytryptophan; 5,7-Dihydroxytryptamine; Animals; Desipramine; Motor Activity; Myoclonus; p-Chl

1978
L-5-Hydroxytryptophan-induced myoclonus in guinea pigs: a model for the study of central serotonin-dopamine interactions.
    Neuropharmacology, 1978, Volume: 17, Issue:11

    Topics: 5-Hydroxytryptophan; Animals; Dopamine; Female; Guinea Pigs; Male; Models, Biological; Myoclonus; Re

1978
p,p'-DDT-induced neurotoxic syndrome: experimental myoclonus.
    Neurology, 1978, Volume: 28, Issue:10

    Topics: 5-Hydroxytryptophan; Animals; Brain Chemistry; Clomipramine; DDT; Hydroxyindoleacetic Acid; Isomeris

1978
L-5-hydroxytryptophan therapy in myoclonus.
    Advances in neurology, 1979, Volume: 26

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Carbidopa; Clomipramine; Double-Blind Method; Drug Eva

1979
L-5-hydroxytryptophan therapy in myoclonus: discussion.
    Advances in neurology, 1979, Volume: 26

    Topics: 5-Hydroxytryptophan; Drug Evaluation; Humans; Myoclonus

1979
Functional independence in post-anoxic myoclonus: contribution of L-5-HTP sodium valproate and clonazepam.
    British medical journal, 1978, Dec-09, Volume: 2, Issue:6152

    Topics: 5-Hydroxytryptophan; Adult; Benzodiazepinones; Clonazepam; Drug Therapy, Combination; Female; Humans

1978
Long-term therapy of myoclonus and other neurologic disorders with L-5-hydroxytryptophan and carbidopa.
    The New England journal of medicine, 1977, Jan-13, Volume: 296, Issue:2

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Brain; Carbidopa; Drug Therapy, Combination; Epilepsie

1977
Clinical, biochemical, and physiological features distinguishing myoclonus responsive to 5-hydroxytryptophan, tryptophan with a monoamine oxidase inhibitor, and clonazepam.
    Brain : a journal of neurology, 1977, Volume: 100, Issue:3

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Benzodiazepinones; Carbidopa; Child, Preschool; Clonaz

1977
Therapy of intention myoclonus with L-5-hydroxytryptophan and a peripheral decarboxylase inhibitor, MK 486.
    Neurology, 1975, Volume: 25, Issue:2

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aromatic Amino Acid Decarboxylase Inhibitors; Carbidopa; Cer

1975
Levodopa-induced myoclonus.
    Archives of neurology, 1975, Volume: 32, Issue:5

    Topics: 5-Hydroxytryptophan; Aged; Amantadine; Amphetamine; Animals; Benztropine; Dopamine Antagonists; Dose

1975
[Letter: Combination of a dopa decarboxylase inhibitor with 5-hydroxytryptophan therapy].
    La Nouvelle presse medicale, 1975, Jan-04, Volume: 4, Issue:1

    Topics: 5-Hydroxytryptophan; Adult; Aromatic Amino Acid Decarboxylase Inhibitors; Dopa Decarboxylase; Drug S

1975
[Ramsay-Hunt syndrome and aniridia in 2 monozygotic twins].
    Revue neurologique, 1975, Volume: 131, Issue:1

    Topics: 5-Hydroxytryptophan; Adolescent; Benzodiazepinones; Blood Group Antigens; Cerebellar Ataxia; Disease

1975
Behavioral supersensitivity to 5-hydroxytryptophan induced by chronic methysergide pretreatment.
    Psychopharmacologia, 1975, Nov-21, Volume: 44, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Behavior; Brain Chemistry; Drug Synergism; Guinea Pigs; Humans; Male;

1975
Myoclonus after 5-hydroxytryptophan in rats with lesions of indoleamine neurons in the central nervous system.
    Neurology, 1976, Volume: 26, Issue:7

    Topics: 5-Hydroxytryptophan; Animals; Benserazide; Brain; Dose-Response Relationship, Drug; Drug Interaction

1976
Beneficial effects of serotonin precursors in postanoxic action myoclonus.
    Neurology, 1976, Volume: 26, Issue:9

    Topics: 5-Hydroxytryptophan; Aged; Carbidopa; Female; Humans; Hydroxyindoleacetic Acid; Hypoxia; Levodopa; M

1976
5-hydroxytryptophan-induced myoclonus: increased sensitivity to serotonin after intracranial 5,7-dihydroxytryptamine in the adult rat.
    Neuropharmacology, 1976, Volume: 15, Issue:8

    Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Brain; Desipramine; Injections; Male; Myoclonus; Rat

1976
L-5-hydroxytryptophan in treatment of several different syndromes in which myoclonus is prominent.
    Neurology, 1976, Volume: 26, Issue:12

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Carbidopa; Child, Preschool; Drug Evaluation; Female; Humans

1976
[Case of intention myoclonus (Lance-Adams syndrome) and a dramatic effect of L-5-hydroxytryptophan].
    Rinsho shinkeigaku = Clinical neurology, 1976, Volume: 16, Issue:9

    Topics: 5-Hydroxytryptophan; Humans; Male; Middle Aged; Myoclonus

1976
Clinical and metabolic observations on the treatment of myoclonus with L-5-HTP and carbidopa.
    Transactions of the American Neurological Association, 1976, Volume: 101

    Topics: 5-Hydroxytryptophan; Adult; Carbidopa; Drug Evaluation; Homovanillic Acid; Humans; Hydrazines; Hydro

1976
Spinal myoclonus: successful treatment with the combination of sodium valproate and L-5-hydroxytryptophan.
    Clinical neuropharmacology, 1991, Volume: 14, Issue:2

    Topics: 5-Hydroxytryptophan; Adult; Drug Therapy, Combination; Humans; Male; Myoclonus; Spinal Cord Diseases

1991
A functional interaction between GABA and 5-HT in inhibiting picrotoxin-induced myoclonus in rats.
    Indian journal of physiology and pharmacology, 1990, Volume: 34, Issue:2

    Topics: 5-Hydroxytryptophan; Aminooxyacetic Acid; Animals; Fenclonine; gamma-Aminobutyric Acid; Male; Myoclo

1990
Palatal myoclonus: treatment with 5-hydroxytryptophan and carbidopa.
    Movement disorders : official journal of the Movement Disorder Society, 1990, Volume: 5, Issue:4

    Topics: 5-Hydroxytryptophan; Adult; Carbidopa; Drug Therapy, Combination; Humans; Male; Myoclonus; Palatal M

1990
Improvement of action myoclonus by an administration of 5-hydroxytryptophan and carbidopa in a child with muscular subsarcolemmal hyperactivity.
    Brain & development, 1990, Volume: 12, Issue:5

    Topics: 5-Hydroxytryptophan; Carbidopa; Child, Preschool; Humans; Male; Muscles; Muscular Diseases; Myoclonu

1990
Biochemistry and therapeutics of posthypoxic myoclonus.
    Advances in neurology, 1986, Volume: 43

    Topics: 5-Hydroxytryptophan; Adrenocorticotropic Hormone; Aspartic Acid; Benzodiazepines; Carbidopa; Electro

1986
Treatment of posthypoxic action myoclonus: implications for the pathophysiology of the disorder.
    Advances in neurology, 1986, Volume: 43

    Topics: 5-Hydroxytryptophan; Benzodiazepines; Clonazepam; Female; Fenclonine; Humans; Hydroxyindoleacetic Ac

1986
Pathological findings in a case of hypoxic myoclonus treated with 5-hydroxytryptophan and a decarboxylase inhibitor.
    Advances in neurology, 1986, Volume: 43

    Topics: 5-Hydroxytryptophan; Aged; Brain; Carbidopa; Diazepam; Electroencephalography; Female; Fenclonine; H

1986
5-HT-mediated myoclonus in the guinea pig as a model of brainstem 5-HT and tryptamine receptor action.
    Advances in neurology, 1986, Volume: 43

    Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Brain; Carbidopa; Disease Models, Animal; Guinea Pig

1986
p,p'-DDT-induced myoclonus in the rat and its application as an animal model of 5-HT-sensitive action myoclonus.
    Advances in neurology, 1986, Volume: 43

    Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Brain; Clonazepam; DDT; Disease Models, Animal; Elec

1986
Possible mechanisms of action of valproic acid in myoclonus.
    Advances in neurology, 1986, Volume: 43

    Topics: 4-Aminobutyrate Transaminase; 5-Hydroxytryptophan; Animals; Brain; gamma-Aminobutyric Acid; Glycine;

1986
Clinical, biochemical, and pharmacological observation in a patient with postasphyxic myoclonus: association to serotonin hyperactivity.
    Clinical neuropharmacology, 1988, Volume: 11, Issue:2

    Topics: 5-Hydroxytryptophan; Aged; Humans; Hydroxyindoleacetic Acid; Hypoxia; Male; Methysergide; Myoclonus;

1988
The proposed role of neurotransmitter receptors in the pathophysiology of human myoclonic disorders.
    Medical hypotheses, 1989, Volume: 30, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Biomechanical Phenomena; Humans; Myoclonus; Neurotransmitter Agents; R

1989
Intracisternal 5,7-dihydroxytryptamine lesions in neonatal and adult rats: comparison of response to 5-hydroxytryptophan.
    Developmental neuroscience, 1989, Volume: 11, Issue:3

    Topics: 5-Hydroxytryptophan; 5,7-Dihydroxytryptamine; Age Factors; Animals; Behavior, Animal; Body Weight; B

1989
Antimyoclonic properties of S2 serotonin receptor antagonists in the rat.
    Neuropharmacology, 1986, Volume: 25, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Brain Chemistry; Butyrophenones; Cinanserin; Ketanserin; Male; Myoclon

1986
Evidence for synergism between the antimyoclonic actions of 5-hydroxytryptophan and clonazepam in rats.
    European journal of pharmacology, 1988, May-10, Volume: 149, Issue:3

    Topics: 5-Hydroxytryptophan; Allylglycine; Animals; Cerebral Cortex; Clonazepam; Dose-Response Relationship,

1988
Estradiol and progesterone influence L-5-hydroxytryptophan-induced myoclonus in male guinea pigs: sex differences in serotonin-steroid interactions.
    Brain research, 1985, Mar-18, Volume: 330, Issue:1

    Topics: 5-Hydroxytryptophan; Androgens; Animals; Drug Interactions; Estradiol; Female; Guinea Pigs; Male; My

1985
p,p'-DDT-induced myoclonus in mice: the effect of enhanced 5-HT neurotransmission.
    Acta pharmacologica et toxicologica, 1985, Volume: 56, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Carbidopa; DDT; Female; Mice; Mice, Inbred Strains; Myoclonus; Paroxet

1985
The effect of intravenous L-5-HTP in the myoclonic encephalopathy of infants.
    Neuropediatrics, 1986, Volume: 17, Issue:2

    Topics: 5-Hydroxytryptophan; Adrenocorticotropic Hormone; Drug Therapy, Combination; Female; Ganglioneuroma;

1986
Experimental study on central effects of carboxyethyl-gamma-aminobutyric acid (CEGABA).
    Il Farmaco; edizione scientifica, 1988, Volume: 43, Issue:4

    Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Brain; Disease Models, Animal; Electroencephalograph

1988
Successful treatment of cherry red spot-myoclonus syndrome with 5-hydroxytryptophan.
    Annals of neurology, 1988, Volume: 24, Issue:3

    Topics: 5-Hydroxytryptophan; Adolescent; Female; Humans; Male; Myoclonus; Neuraminidase; Pedigree; Syndrome

1988
Palatal myoclonus.
    Advances in neurology, 1986, Volume: 43

    Topics: 5-Hydroxytryptophan; Humans; Myoclonus; Palate

1986
Drug-induced myoclonus.
    Advances in neurology, 1986, Volume: 43

    Topics: 5-Hydroxytryptophan; Anesthetics; Animals; Anti-Bacterial Agents; Antidepressive Agents; Bismuth; Ca

1986
L-5-HTP-induced myoclonic jumping behavior in guinea pigs: an update.
    Advances in neurology, 1986, Volume: 43

    Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Bromocriptine; Clonazepam; Disease Models, Animal; Guinea

1986
Serotonin models of myoclonus in the guinea pig and rat.
    Advances in neurology, 1986, Volume: 43

    Topics: 5-Hydroxytryptophan; Animals; Autoradiography; Behavior, Animal; Deoxyglucose; Disease Models, Anima

1986
Serotonin-lesion myoclonic syndromes. I. Neurochemical profile and S-1 receptor binding.
    Brain research, 1986, Jan-29, Volume: 364, Issue:1

    Topics: 5-Hydroxytryptophan; 5,7-Dihydroxytryptamine; Amphetamines; Animals; Biogenic Amines; Brain; Brain C

1986
Serotonin-lesion myoclonic syndromes. II. Analysis of individual syndrome elements, locomotor activity and behavioral correlations.
    Brain research, 1986, Jan-29, Volume: 364, Issue:1

    Topics: 5-Hydroxytryptophan; 5,7-Dihydroxytryptamine; Amphetamines; Animals; Dihydroxytryptamines; Drug Inte

1986
Neuropharmacological profile of ketanserin.
    Il Farmaco; edizione scientifica, 1987, Volume: 42, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Autonomic Nervous System; Behavior, Animal; Electroencephalography; He

1987
Harmala alkaloids and related beta-carbolines: a myoclonic model and antimyoclonic drugs.
    Experimental neurology, 1987, Volume: 96, Issue:3

    Topics: 5-Hydroxytryptophan; Alkaloids; Animals; Carbolines; Male; Motor Activity; Myoclonus; Rats; Rats, In

1987
The guinea pig myoclonic model: behavioral supersensitivity to 5-hydroxytryptophan induced by intracisternal 5,7-dihydroxytryptamine.
    European journal of pharmacology, 1987, Nov-10, Volume: 143, Issue:2

    Topics: 5-Hydroxytryptophan; 5,7-Dihydroxytryptamine; Animals; Behavior, Animal; Brain; Cisterna Magna; Dihy

1987
Neuromuscular effects of monoamine oxidase inhibitors.
    Journal of clinical psychopharmacology, 1985, Volume: 5, Issue:4

    Topics: 5-Hydroxytryptophan; Adult; Animals; Dopamine; Electroencephalography; Female; Humans; Male; Middle

1985
[Case of agrypnia (4 months without sleep) in Morvan's disease. Favorable action of 5-hydroxytryptophan].
    Electroencephalography and clinical neurophysiology, 1974, Volume: 36, Issue:1

    Topics: 5-Hydroxytryptophan; Adult; Chorea; Dose-Response Relationship, Drug; Electroconvulsive Therapy; Ele

1974
Letter: Myoclonus, methysergide, and serotonin.
    Lancet (London, England), 1974, Jun-22, Volume: 1, Issue:7869

    Topics: 5-Hydroxytryptophan; Animals; Dihydroxyphenylalanine; Drug Antagonism; Guinea Pigs; Humans; Methyser

1974
Letter: Treatment of post-anoxic intention myoclonus.
    Lancet (London, England), 1974, Jun-22, Volume: 1, Issue:7869

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Carbidopa; Drug Evaluation; Drug Synergism; Drug Therapy, Co

1974
Letter: Relief of action myoclonus by 5-hydroxytryptophan.
    Lancet (London, England), 1974, Jul-13, Volume: 2, Issue:7872

    Topics: 5-Hydroxytryptophan; Animals; Brain Concussion; Female; Guinea Pigs; Humans; Infusions, Parenteral;

1974
5-Hydroxytryptophan-induced myoclonus in guinea pigs and the possible role of serotonin in infantile myoclonus.
    Neurology, 1973, Volume: 23, Issue:11

    Topics: 5-Hydroxytryptophan; Animals; Chlorpromazine; Guinea Pigs; Injections, Subcutaneous; Male; Methyserg

1973
Serotonergic and antiserotonergic influences on amphetamine-induced stereotyped behavior.
    Journal of the neurological sciences, 1973, Volume: 20, Issue:4

    Topics: 5-Hydroxytryptophan; Acetylcholine; Animals; Basal Ganglia Diseases; Behavior, Animal; Corpus Striat

1973
HVA and 5HIAA CSF measurements and 5HTP trials in some patients with involuntary movements.
    Journal of the neurological sciences, 1973, Volume: 18, Issue:4

    Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Chorea; Dopamine; Dystonia Musculorum Deformans; Femal

1973
[Observations on the use of 5 HTP in clinical medicine].
    Revue neurologique, 1972, Volume: 127, Issue:2

    Topics: 5-Hydroxytryptophan; Epilepsy; Humans; Male; Mental Disorders; Movement Disorders; Myoclonus; Thinki

1972
Studies on the interaction of reserpine, d-amphetamine, apomorphine and 5-hydroxytryptophan.
    Acta pharmacologica et toxicologica, 1974, Volume: 35, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Behavior, Animal; Dextroamphetamine; Dose-Response Relati

1974
Indoleamine antagonists: relative potencies as inhibitors of tryptamine- and 5-hydroxytryptophan-evoked responses.
    British journal of pharmacology, 1974, Volume: 50, Issue:2

    Topics: 5-Hydroxytryptophan; Anilides; Animals; Cinnamates; Cyproheptadine; Ergolines; Female; Foot; Head; M

1974
A model for the quantitative study of central dopaminergic and serotoninergic activity.
    European journal of pharmacology, 1972, Volume: 18, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Caudate Nucleus; Chlorpromazine; Dihydroxyphenylalanine;

1972
[Pharmacological analysis of a case of postanoxic intention and action myoclonus].
    Revue neurologique, 1971, Volume: 124, Issue:1

    Topics: 5-Hydroxytryptophan; Alcohols; Anticonvulsants; Benzoates; Carbamazepine; Chlorpromazine; Diazepam;

1971