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5-hydroxytryptophan and Myelopathy

5-hydroxytryptophan has been researched along with Myelopathy in 3 studies

5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.

Research Excerpts

ExcerptRelevanceReference
" We describe two sisters with hemiplegic migraine, low CSF and platelet serotonin levels, and progressive spastic paraparesis associated with profound spinal cord atrophy whose lower extremity strength and ambulation responded to a precursor replacement strategy (5-hydroxytryptophan and carbidopa administration), an approach that may have broader applicability in myelopathies of diverse etiology where descending serotonergic projections are compromised."7.85Improved strength on 5-hydroxytryptophan and carbidopa in spinal cord atrophy. ( Carleton, B; Horvath, GA; Meisner, L; Selby, K; Stowe, R, 2017)
" We describe two sisters with hemiplegic migraine, low CSF and platelet serotonin levels, and progressive spastic paraparesis associated with profound spinal cord atrophy whose lower extremity strength and ambulation responded to a precursor replacement strategy (5-hydroxytryptophan and carbidopa administration), an approach that may have broader applicability in myelopathies of diverse etiology where descending serotonergic projections are compromised."3.85Improved strength on 5-hydroxytryptophan and carbidopa in spinal cord atrophy. ( Carleton, B; Horvath, GA; Meisner, L; Selby, K; Stowe, R, 2017)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Horvath, GA1
Meisner, L1
Selby, K1
Stowe, R1
Carleton, B1
Jiménez-Jiménez, FJ1
Roldan, A1
Zancada, F1
Molina-Arjona, JA1
Fernandez-Ballesteros, A1
Santos, J1
Chase, TN1

Reviews

1 review available for 5-hydroxytryptophan and Myelopathy

ArticleYear
Serotonergic mechanisms and extrapyramidal function in man.
    Advances in neurology, 1974, Volume: 5

    Topics: 5-Hydroxytryptophan; Carbidopa; Cerebellar Diseases; Creutzfeldt-Jakob Syndrome; Down Syndrome; Extr

1974

Other Studies

2 other studies available for 5-hydroxytryptophan and Myelopathy

ArticleYear
Improved strength on 5-hydroxytryptophan and carbidopa in spinal cord atrophy.
    Journal of the neurological sciences, 2017, Jul-15, Volume: 378

    Topics: 5-Hydroxytryptophan; Adult; Atrophy; Carbidopa; Central Nervous System Agents; Fatal Outcome; Female

2017
Spinal myoclonus: successful treatment with the combination of sodium valproate and L-5-hydroxytryptophan.
    Clinical neuropharmacology, 1991, Volume: 14, Issue:2

    Topics: 5-Hydroxytryptophan; Adult; Drug Therapy, Combination; Humans; Male; Myoclonus; Spinal Cord Diseases

1991