5-hydroxytryptophan has been researched along with Morphine Dependence in 9 studies
5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.
Morphine Dependence: Strong dependence, both physiological and emotional, upon morphine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "It was found that pimozide, haloperidol and alpha-methyl-p-tyrosine (alpha-MT), drugs inhibiting central catecholaminergic (CA) transmission, increased the development of morphine dependence measured as wet dog shakes in rats." | 7.66 | The influence of pimozide, haloperidol, alpha-methyl-p-tyrosine and reserpine on the development of morphine dependence in rats. ( Kruszewska, A; Langwiński, R, 1983) |
| "It was found that pimozide, haloperidol and alpha-methyl-p-tyrosine (alpha-MT), drugs inhibiting central catecholaminergic (CA) transmission, increased the development of morphine dependence measured as wet dog shakes in rats." | 3.66 | The influence of pimozide, haloperidol, alpha-methyl-p-tyrosine and reserpine on the development of morphine dependence in rats. ( Kruszewska, A; Langwiński, R, 1983) |
| "In summary, we conclude that morphine addiction is associated with supersensitivity of 5-HT1A serotonin receptors and alpha2-adrenoceptors (autoreceptors and heteroreceptors) that modulate the synthesis of monoamines in brain." | 1.31 | Supersensitivity of 5-HT1A autoreceptors and alpha2-adrenoceptors regulating monoamine synthesis in the brain of morphine-dependent rats. ( Esteban, S; García-Sevilla, JA; Sastre-Coll, A, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (77.78) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (22.22) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kruszewska, A | 2 |
| Langwiński, R | 2 |
| Contreras, E | 2 |
| Tamayo, L | 2 |
| Quijada, L | 2 |
| Muñoz, M | 1 |
| Harris, GC | 1 |
| Aston-Jones, G | 1 |
| Sastre-Coll, A | 1 |
| Esteban, S | 1 |
| García-Sevilla, JA | 1 |
| Way, EL | 1 |
| Ho, IK | 1 |
| Loh, HH | 1 |
| Cheney, DL | 1 |
| Goldstein, A | 1 |
| Collier, HO | 1 |
| Francis, DL | 1 |
| Henderson, G | 1 |
| Schneider, C | 1 |
9 other studies available for 5-hydroxytryptophan and Morphine Dependence
| Article | Year |
|---|---|
The influence of pimozide, haloperidol, alpha-methyl-p-tyrosine and reserpine on the development of morphine dependence in rats.
Topics: 5-Hydroxytryptophan; alpha-Methyltyrosine; Animals; Catecholamines; Haloperidol; Humans; Male; Methy | 1983 |
Decrease of tolerance and physical dependence on morphine by drugs affecting brain serotonin.
Topics: 5-Hydroxytryptophan; Animals; Brain Chemistry; Fenfluramine; Humans; Mice; Morphine Dependence; Nalo | 1980 |
Augmented accumbal serotonin levels decrease the preference for a morphine associated environment during withdrawal.
Topics: 5-Hydroxytryptophan; Animals; Anxiety; Conditioning, Psychological; Drug Administration Schedule; En | 2001 |
Supersensitivity of 5-HT1A autoreceptors and alpha2-adrenoceptors regulating monoamine synthesis in the brain of morphine-dependent rats.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Autoreceptors; Biogenic Monoam | 2002 |
Partial inhibition of the abstinence syndrome in morphine tolerant-dependent mice following pharmacological denervation.
Topics: 5-Hydroxytryptophan; Animals; Atropine; Behavior, Animal; Denervation; Drug Tolerance; Humans; Methy | 1978 |
[The effect of reserpine on the morphine abstinence syndrome in mice (author's transl)].
Topics: 5-Hydroxytryptophan; Animals; Drug Antagonism; Humans; Levodopa; Male; Mice; Morphine Dependence; Re | 1979 |
Brain 5-hydroxytryptamine and cyclic AMP in morphine tolerance and dependence.
Topics: 5-Hydroxytryptophan; Adrenergic beta-Antagonists; Analgesics; Animals; Body Weight; Brain; Brain Che | 1974 |
The effect of p-chlorophenylalanine on opiate-induced running, analgesia, tolerance and physical dependence in mice.
Topics: 5-Hydroxytryptophan; Analgesia; Animals; Behavior, Animal; Brain Chemistry; Drug Tolerance; Fencloni | 1971 |
Quasi morphine-abstinence syndrome.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Delayed-Action Preparations; Disease Models, Animal; | 1974 |