5-hydroxytryptophan has been researched along with Liver Neoplasms in 14 studies
5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.
Liver Neoplasms: Tumors or cancer of the LIVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The urinary excretion of 5-hydroxyindoleacetic acid, 5-hydroxytryptophan, serotonin, tryptamine, and tyramine and the serum serotonin concentration were determined in 38 consecutive patients with metastatic carcinoid tumors." | 7.66 | Serotonin metabolism in patients with carcinoid tumors: incidence of 5-hydroxytryptophan-secreting tumors. ( Feldman, JM, 1978) |
| "Four of the 23 patients with the carcinoid syndrome (15%) had markedly elevated excretion of 5-hydroxytryptophan." | 5.26 | Serotonin metabolism in patients with carcinoid tumors: incidence of 5-hydroxytryptophan-secreting tumors. ( Feldman, JM, 1978) |
| " Carcinoid tumors with liver metastases, especially those of midgut origin, produce serotonin via the precursors tryptophan and 5-hydroxytryptophan (5-HTP) and this overproduction contributes to the clinical symptoms of the carcinoid syndrome." | 5.07 | Positron emission tomography (PET) in neuroendocrine gastrointestinal tumors. ( Ahlström, H; Bergström, M; Eriksson, B; Långström, B; Lilja, A; Oberg, K, 1993) |
| "The urinary excretion of 5-hydroxyindoleacetic acid, 5-hydroxytryptophan, serotonin, tryptamine, and tyramine and the serum serotonin concentration were determined in 38 consecutive patients with metastatic carcinoid tumors." | 3.66 | Serotonin metabolism in patients with carcinoid tumors: incidence of 5-hydroxytryptophan-secreting tumors. ( Feldman, JM, 1978) |
| "Six patients with midgut carcinoid metastases were examined with 11C-5-HTP PET before and 1 h after oral administration of 100 or 200 mg of CD." | 2.72 | Carbidopa pretreatment improves image interpretation and visualisation of carcinoid tumours with 11C-5-hydroxytryptophan positron emission tomography. ( Bergström, M; Eriksson, B; Långström, B; Lu, L; Oberg, K; Orlefors, H; Sundin, A, 2006) |
| "Carcinoid tumors with liver metastases, especially those of midgut origin, produce serotonin via the precursors tryptophan and 5-hydroxytryptophan (5-HTP) and this overproduction contributes to the clinical symptoms of the carcinoid syndrome." | 2.67 | Positron emission tomography (PET) in neuroendocrine gastrointestinal tumors. ( Ahlström, H; Bergström, M; Eriksson, B; Långström, B; Lilja, A; Oberg, K, 1993) |
| "MRI detected more liver metastases than 5-HTP PET/CT." | 1.46 | Whole-body MRI including diffusion-weighted MRI compared with 5-HTP PET/CT in the detection of neuroendocrine tumors. ( Ahlström, H; Caballero-Corbalán, J; Carlbom, L; Eriksson, B; Granberg, D; Sörensen, J, 2017) |
| "In three patients with carcinoid liver and/or lymph node metastases, we studied the process of tumor tracer uptake and decarboxylation by means of positron emission tomography (PET) using 5-hydroxy-L-tryptophan (5-HTP) 11C-labeled in the beta-position (HTP) and later the same day with 5-HTP 11C-labeled in the carboxyl group (HTC)." | 1.31 | Demonstration of [11C] 5-hydroxy-L-tryptophan uptake and decarboxylation in carcinoid tumors by specific positioning labeling in positron emission tomography. ( Bergström, M; Bjurling, P; Eriksson, B; Långström, B; Lindner, KJ; Oberg, K; Sundin, A, 2000) |
| "Three of 30 patients (10%) with carcinoid tumors metastatic to the liver had large hepatic pseudocysts." | 1.27 | Pseudocystic liver metastases in patients with carcinoid tumors: report of three cases. ( Dent, GA; Feldman, JM, 1984) |
| "Four of the 23 patients with the carcinoid syndrome (15%) had markedly elevated excretion of 5-hydroxytryptophan." | 1.26 | Serotonin metabolism in patients with carcinoid tumors: incidence of 5-hydroxytryptophan-secreting tumors. ( Feldman, JM, 1978) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (57.14) | 18.7374 |
| 1990's | 2 (14.29) | 18.2507 |
| 2000's | 2 (14.29) | 29.6817 |
| 2010's | 2 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Carlbom, L | 1 |
| Caballero-Corbalán, J | 1 |
| Granberg, D | 1 |
| Sörensen, J | 1 |
| Eriksson, B | 5 |
| Ahlström, H | 3 |
| Norlén, O | 1 |
| Nilsson, A | 1 |
| Krause, J | 1 |
| Stålberg, P | 1 |
| Hellman, P | 1 |
| Sundin, A | 3 |
| BIRKENHAEGER, JC | 1 |
| GRAHAME-SMITH, DG | 2 |
| HALE, JF | 1 |
| LANE-MITCHELL, W | 1 |
| Orlefors, H | 1 |
| Lu, L | 1 |
| Oberg, K | 4 |
| Långström, B | 4 |
| Bergström, M | 4 |
| Dent, GA | 1 |
| Feldman, JM | 2 |
| Lilja, A | 2 |
| Bjurling, P | 2 |
| Lindner, KJ | 2 |
| Lipsett, MB | 1 |
| Porst, H | 1 |
| Naas, W | 1 |
| Renger, F | 1 |
| Dökert, B | 1 |
| Platzbecker, H | 1 |
1 review available for 5-hydroxytryptophan and Liver Neoplasms
| Article | Year |
|---|---|
Progress report: the carcinoid syndrome.
Topics: 5-Hydroxytryptophan; Antineoplastic Agents; Bradykinin; Diarrhea; Heart Valve Diseases; Humans; Hydr | 1970 |
4 trials available for 5-hydroxytryptophan and Liver Neoplasms
| Article | Year |
|---|---|
11C-5-hydroxytryptophan positron emission tomography after radiofrequency ablation of neuroendocrine tumor liver metastases.
Topics: 5-Hydroxytryptophan; Ablation Techniques; Carbon Radioisotopes; Follow-Up Studies; Humans; Liver Neo | 2012 |
Carbidopa pretreatment improves image interpretation and visualisation of carcinoid tumours with 11C-5-hydroxytryptophan positron emission tomography.
Topics: 5-Hydroxytryptophan; Carbidopa; Carbon Radioisotopes; Carcinoid Tumor; Female; Humans; Image Enhance | 2006 |
Positron emission tomography (PET) in neuroendocrine gastrointestinal tumors.
Topics: 5-Hydroxytryptophan; Adenoma, Islet Cell; Carbon Radioisotopes; Carcinoid Tumor; Female; Gastrointes | 1993 |
Positron-emission tomography as a radiological technique in neuroendocrine gastrointestinal tumors.
Topics: 5-Hydroxytryptophan; Carbon Radioisotopes; Carcinoid Tumor; Gastrointestinal Neoplasms; Humans; Inte | 1994 |
9 other studies available for 5-hydroxytryptophan and Liver Neoplasms
| Article | Year |
|---|---|
Whole-body MRI including diffusion-weighted MRI compared with 5-HTP PET/CT in the detection of neuroendocrine tumors.
Topics: 5-Hydroxytryptophan; Adult; Aged; Bone Neoplasms; Contrast Media; Diffusion Magnetic Resonance Imagi | 2017 |
METASTASIZING NEUROBLASTOMA WITH EXCRETION OF 5-HYDROXYINDOLEACETIC ACID, SEROTONIN AND 5-HYDROXYTRYPTOPHAN.
Topics: 5-Hydroxytryptophan; Abdominal Neoplasms; Chromatography; Humans; Hydroxyindoleacetic Acid; Indoleac | 1963 |
TRYPTOPHAN HYDROXYLATION IN CARCINOID TUMOURS.
Topics: 5-Hydroxytryptophan; Amines; Autoradiography; Carbon Isotopes; Carboxy-Lyases; Carcinoid Tumor; Chro | 1964 |
THE CARCINOID SYNDROME. CASE REPORT AND REVIEW.
Topics: 5-Hydroxytryptophan; Antineoplastic Agents; Appendectomy; Drug Therapy; Humans; Liver Neoplasms; Mal | 1964 |
Pseudocystic liver metastases in patients with carcinoid tumors: report of three cases.
Topics: 5-Hydroxytryptophan; Adenocarcinoma; Adrenocorticotropic Hormone; Adult; Aged; Blood Platelets; Carc | 1984 |
Demonstration of [11C] 5-hydroxy-L-tryptophan uptake and decarboxylation in carcinoid tumors by specific positioning labeling in positron emission tomography.
Topics: 5-Hydroxytryptophan; Antineoplastic Agents; Carbon Radioisotopes; Carcinoid Tumor; Decarboxylation; | 2000 |
Serotonin metabolism in patients with carcinoid tumors: incidence of 5-hydroxytryptophan-secreting tumors.
Topics: 5-Hydroxytryptophan; Adult; Aged; Carcinoid Tumor; Female; Gastrointestinal Neoplasms; Humans; Hydro | 1978 |
Humoral syndromes associated with cancer.
Topics: 5-Hydroxytryptophan; Carcinoid Tumor; Carcinoma, Hepatocellular; Carotid Body Tumor; Catecholamines; | 1965 |
[Carcinoid and carcinoid syndrome].
Topics: 5-Hydroxytryptophan; Bradykinin; Carcinoid Tumor; Female; Gastrointestinal Neoplasms; Hepatomegaly; | 1974 |