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5-hydroxytryptophan and Inborn Errors of Metabolism

5-hydroxytryptophan has been researched along with Inborn Errors of Metabolism in 11 studies

5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.

Research Excerpts

ExcerptRelevanceReference
"Classic L-dopa-responsive dystonia is characterized by the triad of dystonia, diurnal fluctuation of signs, and dramatic response of signs to low-dose L-dopa therapy."1.43What Is Not in the Name? Dopa-Responsive Dystonia May Respond to More Than L-Dopa. ( Friedman, JR, 2016)
"As is typical in dopa-responsive dystonia, these patients displayed dramatic improvement with L-dopa/carbidopa therapy."1.43What Is Not in the Name? Dopa-Responsive Dystonia May Respond to More Than L-Dopa. ( Friedman, JR, 2016)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19905 (45.45)18.7374
1990's3 (27.27)18.2507
2000's2 (18.18)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Friedman, JR1
Kusmierska, K1
Jansen, EE1
Jakobs, C1
Szymanska, K1
Malunowicz, E1
Meilei, D1
Thony, B2
Blau, N3
Tryfon, J1
Rokicki, D1
Pronicka, E1
Sykut-Cegielska, J1
Echenne, B1
Roubertie, A1
Assmann, B1
Lutz, T1
Penzien, JM1
Hoffmann, GF1
Dhondt, JL1
Suzuki, T1
Hyland, K1
Clayton, PT1
Tyce, GM1
Flock, EV1
Owen, CA1
Williams, RH1
Hsia, DY1
Ebadi, MS1
Bostad, R1
Pellegrino, RJ1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
SIngle-Stage, Open-Label, Safety and Efficacy Study of Adeno-Associated Virus Encoding Human Aromatic L-Amino Acid Decarboxylase by Magnetic Resonance MR-guided Infusion Into Midbrain in Pediatric Patients With AADC Deficiency[NCT02852213]Phase 131 participants (Anticipated)Interventional2016-07-31Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for 5-hydroxytryptophan and Inborn Errors of Metabolism

ArticleYear
[Inborn errors of catecholamine metabolism].
    Ryoikibetsu shokogun shirizu, 1998, Issue:19 Pt 2

    Topics: 5-Hydroxytryptophan; Aromatic-L-Amino-Acid Decarboxylases; Biopterins; Catecholamines; Diagnosis, Di

1998
Biogenic amines and psychiatry.
    The Australian and New Zealand journal of psychiatry, 1971, Volume: 5, Issue:1

    Topics: 5-Hydroxytryptophan; Affective Symptoms; Amines; Amphetamine; Anxiety Disorders; Attention Deficit D

1971
Biochemical factors in mental retardation.
    Proceedings of the annual meeting of the American Psychopathological Association, 1967, Volume: 56

    Topics: 5-Hydroxytryptophan; Animals; Brain Chemistry; Diet Therapy; Female; Guinea Pigs; Haplorhini; Humans

1967

Other Studies

8 other studies available for 5-hydroxytryptophan and Inborn Errors of Metabolism

ArticleYear
What Is Not in the Name? Dopa-Responsive Dystonia May Respond to More Than L-Dopa.
    Pediatric neurology, 2016, Volume: 59

    Topics: 5-Hydroxytryptophan; Adolescent; Anti-Dyskinesia Agents; Carbidopa; Diseases in Twins; Dopamine Agon

2016
Sepiapterin reductase deficiency in a 2-year-old girl with incomplete response to treatment during short-term follow-up.
    Journal of inherited metabolic disease, 2009, Volume: 32 Suppl 1

    Topics: 5-Hydroxytryptophan; Alcohol Oxidoreductases; Biogenic Amines; Child, Preschool; Dystonia; Female; F

2009
Sepiapterin reductase deficiency: clinical presentation and evaluation of long-term therapy.
    Pediatric neurology, 2006, Volume: 35, Issue:5

    Topics: 5-Hydroxytryptophan; Adolescent; Alcohol Oxidoreductases; Antidepressive Agents, Second-Generation;

2006
Tetrahydrobiopterin deficiency and an international database of patients.
    Advances in experimental medicine and biology, 1993, Volume: 338

    Topics: 5-Hydroxytryptophan; Alcohol Oxidoreductases; Biomarkers; Biopterins; Carbidopa; Child; Dihydropteri

1993
Aromatic L-amino acid decarboxylase deficiency: diagnostic methodology.
    Clinical chemistry, 1992, Volume: 38, Issue:12

    Topics: 5-Hydroxytryptophan; Aromatic-L-Amino-Acid Decarboxylases; Child; Child, Preschool; Chromatography,

1992
Metabolism of serotonin by the isolated perfused rat liver--effect of glucuronyl transferase deficiency or monoamine oxidase inhibition.
    Biochemical pharmacology, 1968, Volume: 17, Issue:8

    Topics: 5-Hydroxytryptophan; Animals; Bile; Blood Platelets; Carbon Isotopes; Chromatography, Paper; Depress

1968
Metabolism and mentation.
    The Journal of clinical endocrinology and metabolism, 1970, Volume: 31, Issue:5

    Topics: 5-Hydroxytryptophan; Acetylcholine; Amino Acid Metabolism, Inborn Errors; Aminobutyrates; Basal Gang

1970
Impairment of pyridoxal phosphate dependent metabolic reactions in a child with subacute necrotizing encephalopathy.
    Journal of neurology, neurosurgery, and psychiatry, 1969, Volume: 32, Issue:5

    Topics: 5-Hydroxytryptophan; Amines; Autopsy; Basal Ganglia; Brain Diseases; Carboxy-Lyases; Dopamine; Femal

1969