5-hydroxytryptophan has been researched along with Hypercapnia in 5 studies
5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.
Hypercapnia: A clinical manifestation of abnormal increase in the amount of carbon dioxide in arterial blood.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In view of the fact that diazepam has been shown to prevent an increase in catecholamine synthesis and/or turnover rates in stressful situations, and to modify the cerebral metabolic (and circulatory) response to hypoxia and hypercapnia, the influence of the drug on synthesis rates of DOPA and 5-HTP in three regions of the rat brain were studied under normoxic-normocapnic conditions, as well as in hypoxia and hypercapnia." | 7.66 | Effect of diazepam on cerebral monoamine synthesis during hypoxia and hypercapnia in the rat. ( Carlsson, A; Dahlgren, N; Sakabe, T; Siesjö, BK, 1982) |
| "The effects of induced hypo- and hypercapnia upon the rate of hydroxylation of tryptophan and tyrosine in the rat brain were studied by measuring the accumulation of 5-HTP and DOPA following administration of the aromatic L-aminoacid decarboxylase inhibitor 3-hydroxybenzylhydrazine HCl (NSD 1015)." | 7.65 | Effect of hypercapnia and hypocapnia on tryptophan and tyrosine hydroxylation in rat brain. ( Carlsson, A; Holmin, T; Lindqvist, M; Siesjö, BK, 1977) |
| " Monoamine synthesis in whole brain was measured during, and at various intervals after, hypercapnia by estimating the accumulation of dihydroxyphenylalanine (DOPA) and 5-hydroxytryptophan (5-HTP) after inhibition of aromatic L-amino-acid decarboxylase with NSD 1015." | 3.66 | Monoamine synthesis and concentration in neonatal rat brain during hypercapnia and recovery. ( Hedner, T; Lundborg, P, 1982) |
| "In view of the fact that diazepam has been shown to prevent an increase in catecholamine synthesis and/or turnover rates in stressful situations, and to modify the cerebral metabolic (and circulatory) response to hypoxia and hypercapnia, the influence of the drug on synthesis rates of DOPA and 5-HTP in three regions of the rat brain were studied under normoxic-normocapnic conditions, as well as in hypoxia and hypercapnia." | 3.66 | Effect of diazepam on cerebral monoamine synthesis during hypoxia and hypercapnia in the rat. ( Carlsson, A; Dahlgren, N; Sakabe, T; Siesjö, BK, 1982) |
| "The effects of 1-h exposure to hypercapnia (PaCO2, 90-110 MMHg) on cerebral indole amine metabolism were studied in rats by measurement of cerebral hemisphere contents of tryptophan, 5-hydroxytryptophan (5-HTP), 5-hydroxytryptamine (5-HT), and 5-hydroxyindoleacetic acid (5-HIAA), 5-HIAA content was increased after 1-h exposure to hypercapnia, whereas tryptophan, 5-HTP, and 5-HT remained unchanged from control." | 3.66 | The effects of acute hypercapnia on cerebral indole amine metabolism. ( MacMillan, V, 1978) |
| "The effects of induced hypo- and hypercapnia upon the rate of hydroxylation of tryptophan and tyrosine in the rat brain were studied by measuring the accumulation of 5-HTP and DOPA following administration of the aromatic L-aminoacid decarboxylase inhibitor 3-hydroxybenzylhydrazine HCl (NSD 1015)." | 3.65 | Effect of hypercapnia and hypocapnia on tryptophan and tyrosine hydroxylation in rat brain. ( Carlsson, A; Holmin, T; Lindqvist, M; Siesjö, BK, 1977) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hedner, T | 1 |
| Lundborg, P | 1 |
| Sakabe, T | 1 |
| Dahlgren, N | 1 |
| Carlsson, A | 3 |
| Siesjö, BK | 2 |
| Holmin, T | 1 |
| Lindqvist, M | 1 |
| MacMillan, V | 1 |
| Brown, RM | 1 |
| Snider, SR | 1 |
5 other studies available for 5-hydroxytryptophan and Hypercapnia
| Article | Year |
|---|---|
Monoamine synthesis and concentration in neonatal rat brain during hypercapnia and recovery.
Topics: 5-Hydroxytryptophan; Animals; Animals, Newborn; Brain; Dihydroxyphenylalanine; Dopamine; Hydrazines; | 1982 |
Effect of diazepam on cerebral monoamine synthesis during hypoxia and hypercapnia in the rat.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Brain; Cerebrovascular Circulation; Diazepam; Dihydroxyph | 1982 |
Effect of hypercapnia and hypocapnia on tryptophan and tyrosine hydroxylation in rat brain.
Topics: 5-Hydroxytryptophan; Amino Acids; Ammonia; Animals; Brain; Carbohydrate Metabolism; Carbon Dioxide; | 1977 |
The effects of acute hypercapnia on cerebral indole amine metabolism.
Topics: 5-Hydroxytryptophan; Amines; Animals; Brain; Hydrazines; Hydroxyindoleacetic Acid; Hydroxylation; Hy | 1978 |
Changes in biogenic amine synthesis and turnover induced by hypoxia and/or foot shock stress. II. The central nervous system.
Topics: 5-Hydroxytryptophan; Animals; Brain; Brain Chemistry; Brain Stem; Corpus Striatum; Depression, Chemi | 1974 |