5-hydroxytryptophan has been researched along with Huntington Disease in 5 studies
5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.
Huntington Disease: A familial disorder inherited as an autosomal dominant trait and characterized by the onset of progressive CHOREA and DEMENTIA in the fourth or fifth decade of life. Common initial manifestations include paranoia; poor impulse control; DEPRESSION; HALLUCINATIONS; and DELUSIONS. Eventually intellectual impairment; loss of fine motor control; ATHETOSIS; and diffuse chorea involving axial and limb musculature develops, leading to a vegetative state within 10-15 years of disease onset. The juvenile variant has a more fulminant course including SEIZURES; ATAXIA; dementia; and chorea. (From Adams et al., Principles of Neurology, 6th ed, pp1060-4)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Roccatagliata, G | 1 |
| Pizio, N | 1 |
| Farinini, D | 1 |
| Firpo, MP | 1 |
| Bartolini, A | 1 |
| Bacigalupo, F | 1 |
| Albano, C | 1 |
| Cederbaum, S | 1 |
| Tourian, AY | 1 |
| Chase, TN | 1 |
| Saïd, G | 1 |
1 review available for 5-hydroxytryptophan and Huntington Disease
| Article | Year |
|---|---|
Serotonergic mechanisms and extrapyramidal function in man.
Topics: 5-Hydroxytryptophan; Carbidopa; Cerebellar Diseases; Creutzfeldt-Jakob Syndrome; Down Syndrome; Extr | 1974 |
1 trial available for 5-hydroxytryptophan and Huntington Disease
| Article | Year |
|---|---|
Administration of 5-hydroxy-L-tryptophan to individuals with Huntington's chorea.
Topics: 5-Hydroxytryptophan; Adult; Brain; Evaluation Studies as Topic; Female; Humans; Huntington Disease; | 1972 |
3 other studies available for 5-hydroxytryptophan and Huntington Disease
| Article | Year |
|---|---|
[Effect of fenfluramine in Huntington Chorea].
Topics: 5-Hydroxytryptophan; Adult; Female; Fenfluramine; Homovanillic Acid; Humans; Huntington Disease; Hyd | 1983 |
Tests for Huntington's chorea.
Topics: 5-Hydroxytryptophan; Dihydroxyphenylalanine; Humans; Huntington Disease | 1971 |
[Dystonias].
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Dihydroxyphenylalanine; Dystonia Musculorum Deformans; Extra | 1972 |