5-hydroxytryptophan has been researched along with Fibromyalgia in 8 studies
5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.
Fibromyalgia: A common nonarticular rheumatic syndrome characterized by myalgia and multiple points of focal muscle tenderness to palpation (trigger points). Muscle pain is typically aggravated by inactivity or exposure to cold. This condition is often associated with general symptoms, such as sleep disturbances, fatigue, stiffness, HEADACHES, and occasionally DEPRESSION. There is significant overlap between fibromyalgia and the chronic fatigue syndrome (FATIGUE SYNDROME, CHRONIC). Fibromyalgia may arise as a primary or secondary disease process. It is most frequent in females aged 20 to 50 years. (From Adams et al., Principles of Neurology, 6th ed, p1494-95)
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study fibromyalgia sufferers were randomly administered a combination of monoamine-oxidase inhibitors (MAOIs)-A/B with 5-HTP, 5-HTP alone, MAOIs-A/B alone, or the tricyclic drug amitriptyline in order to compare the efficacy of these treatments." | 5.08 | Fibromyalgia and migraine, two faces of the same mechanism. Serotonin as the common clue for pathogenesis and therapy. ( Nicolodi, M; Sicuteri, F, 1996) |
| "The recently shown high prevalence of migraine in the population of fibromyalgia sufferers, suggests a common ground shared by fibromyalgia and migraine." | 2.68 | Fibromyalgia and migraine, two faces of the same mechanism. Serotonin as the common clue for pathogenesis and therapy. ( Nicolodi, M; Sicuteri, F, 1996) |
| "Migraine has been demonstrated to be characterized by a defect in the serotonergic and adrenergic systems." | 2.68 | Fibromyalgia and migraine, two faces of the same mechanism. Serotonin as the common clue for pathogenesis and therapy. ( Nicolodi, M; Sicuteri, F, 1996) |
| "Fibromyalgia is a chronic widespread pain condition affecting millions of people worldwide." | 2.58 | Combination pharmacotherapy for the treatment of fibromyalgia in adults. ( Gilron, I; Moore, RA; Shum, B; Thorpe, J; Wiffen, PJ, 2018) |
| " 5-HTP is well absorbed from an oral dose, with about 70 percent ending up in the bloodstream." | 2.40 | 5-Hydroxytryptophan: a clinically-effective serotonin precursor. ( Birdsall, TC, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 7 (87.50) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Thorpe, J | 1 |
| Shum, B | 1 |
| Moore, RA | 1 |
| Wiffen, PJ | 1 |
| Gilron, I | 1 |
| Goodnick, PJ | 1 |
| Sandoval, R | 1 |
| Nicolodi, M | 1 |
| Sicuteri, F | 1 |
| Birdsall, TC | 1 |
| Juhl, JH | 1 |
| Sarzi Puttini, P | 1 |
| Caruso, I | 1 |
| Cho, WK | 1 |
| Stollerman, GH | 1 |
5 reviews available for 5-hydroxytryptophan and Fibromyalgia
| Article | Year |
|---|---|
Combination pharmacotherapy for the treatment of fibromyalgia in adults.
Topics: 5-Hydroxytryptophan; Acetaminophen; Adult; Amitriptyline; Anti-Inflammatory Agents, Non-Steroidal; A | 2018 |
Psychotropic treatment of chronic fatigue syndrome and related disorders.
Topics: 5-Hydroxytryptophan; Amitriptyline; Antidepressive Agents, Tricyclic; Comorbidity; Depressive Disord | 1993 |
5-Hydroxytryptophan: a clinically-effective serotonin precursor.
Topics: 5-Hydroxytryptophan; Contraindications; Depressive Disorder; Fibromyalgia; Headache; Humans; Obesity | 1998 |
Fibromyalgia and the serotonin pathway.
Topics: 5-Hydroxytryptophan; Fibromyalgia; Humans; Serotonin; Tryptophan | 1998 |
Chronic fatigue syndrome.
Topics: 5-Hydroxytryptophan; Adult; Clinical Protocols; Decision Trees; Depressive Disorder; Diagnosis, Diff | 1992 |
1 trial available for 5-hydroxytryptophan and Fibromyalgia
| Article | Year |
|---|---|
Fibromyalgia and migraine, two faces of the same mechanism. Serotonin as the common clue for pathogenesis and therapy.
Topics: 5-Hydroxytryptophan; Amitriptyline; Antidepressive Agents, Tricyclic; Anxiety; Drug Therapy, Combina | 1996 |
2 other studies available for 5-hydroxytryptophan and Fibromyalgia
| Article | Year |
|---|---|
5-hydroxytryptophan.
Topics: 5-Hydroxytryptophan; Contraindications; Depressive Disorder; Fibromyalgia; Headache; Humans; Obesity | 1998 |
Primary fibromyalgia syndrome and 5-hydroxy-L-tryptophan: a 90-day open study.
Topics: 5-Hydroxytryptophan; Female; Fibromyalgia; Humans; Male; Middle Aged; Pain; Time Factors | 1992 |