5-hydroxytryptophan has been researched along with Disease Models, Animal in 79 studies
5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Corylin significantly alleviated colitis symptoms and inhibited inflammatory response in the colon and brain of DSS-induced chronic UC mice." | 8.31 | Corylin ameliorates chronic ulcerative colitis via regulating the gut-brain axis and promoting 5-hydroxytryptophan production in the colon. ( Chen, LH; Wang, ZJ; Xu, J; Xu, QX; Xu, W; Yang, XW, 2023) |
| "Corylin administration ameliorated DSS-induced colitis and inhibited intestinal inflammation and neuroinflammation via regulating the inflammation interactions across gut-brain axis and increasing 5-HTP generation in the colon." | 8.31 | Corylin ameliorates chronic ulcerative colitis via regulating the gut-brain axis and promoting 5-hydroxytryptophan production in the colon. ( Chen, LH; Wang, ZJ; Xu, J; Xu, QX; Xu, W; Yang, XW, 2023) |
| "), potentiated the 5-hydroxytryptophan (5-HTP)-induced head twitch responses in mice and antagonized the reserpine-induced hypothermia in rats." | 7.77 | Evaluation of anti-depressant-like activity of linezolid, an oxazolidinone class derivative - an investigation using behavioral tests battery of depression. ( Bhatt, S; Gautam, B; Jindal, A; Mahesh, R; Pandey, D, 2011) |
| " The aim of the present work is to study alterations in this tryptophan metabolism in rats with experimental Porphyria Cutanea Tarda induced by hexachlorobenzene." | 7.72 | Tryptophan metabolism via serotonin in rats with hexachlorobenzene experimental porphyria. ( Aldonatti, C; Llambías, EB; San Martín de Viale, LC, 2003) |
| "Acute pretreatment with clinically equivalent doses of antidepressive drugs has been observed to block D,L-5-hydroxytryptophan (5-HTP) induced behavioral depression in rats working on a food-reinforced operant schedule." | 7.67 | Postsynaptic serotonergic blockade following chronic antidepressive treatment with trazodone in an animal model of depression. ( Aprison, MH; Hendrie, HC; Hingtgen, JN, 1984) |
| "To test the hypothesis that a new potent and selective 5-HT2 receptor antagonist would be an excellent blocker of D,L-5-hydroxytryptophan (5-HTP)-induced response suppression in an animal model of depression, we administered LY53857 60 min prior to 5-HTP injections into rats working on an operant schedule for milk reinforcement." | 7.67 | Blockade of a 5-hydroxytryptophan-induced animal model of depression with a potent and selective 5-HT2 receptor antagonist (LY53857). ( Aprison, MH; Fuller, RW; Hingtgen, JN; Mason, NR, 1985) |
| "Harmine, a hallucinogen with potent monoamine oxidase inhibitory properties, induced abnormal behavior, including tremor, scratching, head twitch and cage biting, in the mouse." | 7.66 | Pharmacological characteristics of abnormal behavior induced by harmine with special reference to tremor in mice. ( Fujiwara, M; Hashimoto, Y; Kataoka, Y; Kawanishi, K; Ueki, S, 1981) |
| "Corylin is a representative flavonoid compound isolated from the Psoraleae Fructus." | 5.91 | Corylin ameliorates chronic ulcerative colitis via regulating the gut-brain axis and promoting 5-hydroxytryptophan production in the colon. ( Chen, LH; Wang, ZJ; Xu, J; Xu, QX; Xu, W; Yang, XW, 2023) |
| "Chronic ulcerative colitis (UC) is a lifelong disease, patients with chronic UC have a high prevalence of common mental disorders." | 5.91 | Corylin ameliorates chronic ulcerative colitis via regulating the gut-brain axis and promoting 5-hydroxytryptophan production in the colon. ( Chen, LH; Wang, ZJ; Xu, J; Xu, QX; Xu, W; Yang, XW, 2023) |
| "Mood disorders and constipation are often comorbid, yet their shared etiologies have rarely been explored." | 5.51 | Effects of Serotonin and Slow-Release 5-Hydroxytryptophan on Gastrointestinal Motility in a Mouse Model of Depression. ( Bunnett, NW; Caron, MG; Carson, W; Del Colle, A; Israelyan, N; Jacobsen, JPR; Jensen, DD; Latorre, R; Law, K; Li, Z; Luna, RA; Madra, M; Margolis, KG; Park, Y; Rahim, R; Saurman, V; Xing, A, 2019) |
| "Pretreatment with risperidone (0." | 5.32 | Memantine, an NMDA antagonist, prevents the development of hyperthermia in an animal model for serotonin syndrome. ( Kato, S; Nisijima, K; Shioda, K; Takano, K; Yoshino, T, 2004) |
| "Pre-treatment with diazepam, 10 and 20mg/kg, and chlormethiazole, 50 and 100mg/kg, attenuated the development of hyperthermia." | 5.32 | Diazepam and chlormethiazole attenuate the development of hyperthermia in an animal model of the serotonin syndrome. ( Kato, S; Nisijima, K; Shioda, K; Takano, K; Yoshino, T, 2003) |
| " Chronic administration of trazodone (2 mg/kg trazodone/day) also resulted in a significant blockade of the 5-HTP effect (75%)." | 5.27 | Postsynaptic serotonergic blockade following chronic antidepressive treatment with trazodone in an animal model of depression. ( Aprison, MH; Hendrie, HC; Hingtgen, JN, 1984) |
| "Pretreatment with desipramine (2." | 5.27 | Blockade of a 5-hydroxytryptophan-induced animal model of depression with a potent and selective 5-HT2 receptor antagonist (LY53857). ( Aprison, MH; Fuller, RW; Hingtgen, JN; Mason, NR, 1985) |
| "Corylin administration ameliorated DSS-induced colitis and inhibited intestinal inflammation and neuroinflammation via regulating the inflammation interactions across gut-brain axis and increasing 5-HTP generation in the colon." | 4.31 | Corylin ameliorates chronic ulcerative colitis via regulating the gut-brain axis and promoting 5-hydroxytryptophan production in the colon. ( Chen, LH; Wang, ZJ; Xu, J; Xu, QX; Xu, W; Yang, XW, 2023) |
| "Corylin significantly alleviated colitis symptoms and inhibited inflammatory response in the colon and brain of DSS-induced chronic UC mice." | 4.31 | Corylin ameliorates chronic ulcerative colitis via regulating the gut-brain axis and promoting 5-hydroxytryptophan production in the colon. ( Chen, LH; Wang, ZJ; Xu, J; Xu, QX; Xu, W; Yang, XW, 2023) |
| " Changes in breathing and cardiac electrical activity in DBA/1 and C57BL/6J mice that incurred sudden death during generalized seizures evoked by pentylenetetrazole (PTZ) were studied by plethysmography and electrocardiography." | 3.83 | 5-Hydroxytryptophan, a precursor for serotonin synthesis, reduces seizure-induced respiratory arrest. ( Cotten, JF; Feng, HJ; Xue, Q; Yang, X; Zhang, H; Zhao, H, 2016) |
| "), potentiated the 5-hydroxytryptophan (5-HTP)-induced head twitch responses in mice and antagonized the reserpine-induced hypothermia in rats." | 3.77 | Evaluation of anti-depressant-like activity of linezolid, an oxazolidinone class derivative - an investigation using behavioral tests battery of depression. ( Bhatt, S; Gautam, B; Jindal, A; Mahesh, R; Pandey, D, 2011) |
| " The aim of the present work is to study alterations in this tryptophan metabolism in rats with experimental Porphyria Cutanea Tarda induced by hexachlorobenzene." | 3.72 | Tryptophan metabolism via serotonin in rats with hexachlorobenzene experimental porphyria. ( Aldonatti, C; Llambías, EB; San Martín de Viale, LC, 2003) |
| "Since reserpine precipitates depression in some hypertensive patients, we tested this drug on our animal model of depression." | 3.67 | Potentiated 5-hydroxytryptophan induced response suppression in rats following chronic reserpine. ( Aprison, MH; Brugge, KL; Hingtgen, JN, 1987) |
| "Acute pretreatment with clinically equivalent doses of antidepressive drugs has been observed to block D,L-5-hydroxytryptophan (5-HTP) induced behavioral depression in rats working on a food-reinforced operant schedule." | 3.67 | Postsynaptic serotonergic blockade following chronic antidepressive treatment with trazodone in an animal model of depression. ( Aprison, MH; Hendrie, HC; Hingtgen, JN, 1984) |
| " Catecholamines, to a lesser extent the indolamine, serotonin, and the inhibitory transmitter gamma-aminobutyric acid all alter seizures as do less well understood intrinsic hormones and pentapeptides." | 3.67 | Evidence for neurotransmitter abnormalities related to seizure activity in the epileptic baboon. ( Killam, EK; Killam, KF, 1984) |
| "To test the hypothesis that a new potent and selective 5-HT2 receptor antagonist would be an excellent blocker of D,L-5-hydroxytryptophan (5-HTP)-induced response suppression in an animal model of depression, we administered LY53857 60 min prior to 5-HTP injections into rats working on an operant schedule for milk reinforcement." | 3.67 | Blockade of a 5-hydroxytryptophan-induced animal model of depression with a potent and selective 5-HT2 receptor antagonist (LY53857). ( Aprison, MH; Fuller, RW; Hingtgen, JN; Mason, NR, 1985) |
| "Harmine, a hallucinogen with potent monoamine oxidase inhibitory properties, induced abnormal behavior, including tremor, scratching, head twitch and cage biting, in the mouse." | 3.66 | Pharmacological characteristics of abnormal behavior induced by harmine with special reference to tremor in mice. ( Fujiwara, M; Hashimoto, Y; Kataoka, Y; Kawanishi, K; Ueki, S, 1981) |
| "To further test the new hypersensitive postsynaptic serotonin (5-HT) receptor theory of depression bases on or animal model, it was necessary to demonstrate that some of the currently used antidepressive drugs can block D,L-5-hydroxytryptophan (5-HTP) induced depression acting through postsynaptic rather than presynaptic mechanisms." | 3.66 | Postsynaptic action by four antidepressive drugs in an animal model of depression. ( Aprison, MH; Hingtgen, JN; Nagayama, H, 1981) |
| "Rats working on a food-reinforced operant schedule and exhibiting behavioral depression following administration of D,L-5-hydroxytryptophan (5-HTP) were pretreated with one of three drugs: methysergide, fluoxetine, or amitriptyline." | 3.66 | Pre- and postsynaptic serotonergic manipulations in an animal model of depression. ( Aprison, MH; Hingtgen, JN; Nagayama, H, 1980) |
| "5-Hydroxytryptophan has the opposite effect exacerbating the behavioural response to the aversive situation." | 2.38 | The pharmacology of the 5-HT4 receptor. ( Costall, B; Naylor, RJ, 1993) |
| "Corylin is a representative flavonoid compound isolated from the Psoraleae Fructus." | 1.91 | Corylin ameliorates chronic ulcerative colitis via regulating the gut-brain axis and promoting 5-hydroxytryptophan production in the colon. ( Chen, LH; Wang, ZJ; Xu, J; Xu, QX; Xu, W; Yang, XW, 2023) |
| "Chronic ulcerative colitis (UC) is a lifelong disease, patients with chronic UC have a high prevalence of common mental disorders." | 1.91 | Corylin ameliorates chronic ulcerative colitis via regulating the gut-brain axis and promoting 5-hydroxytryptophan production in the colon. ( Chen, LH; Wang, ZJ; Xu, J; Xu, QX; Xu, W; Yang, XW, 2023) |
| "Mood disorders and constipation are often comorbid, yet their shared etiologies have rarely been explored." | 1.51 | Effects of Serotonin and Slow-Release 5-Hydroxytryptophan on Gastrointestinal Motility in a Mouse Model of Depression. ( Bunnett, NW; Caron, MG; Carson, W; Del Colle, A; Israelyan, N; Jacobsen, JPR; Jensen, DD; Latorre, R; Law, K; Li, Z; Luna, RA; Madra, M; Margolis, KG; Park, Y; Rahim, R; Saurman, V; Xing, A, 2019) |
| "Psoriasis is a chronic autoimmune disease with keratinocyte activation and lymphocyte infiltration in the skin." | 1.48 | 5-hydroxytryptophan attenuates imiquimod-induced psoriasiform dermatitis probably through inhibition of IL-17A production and keratinocyte activation. ( Hsu, PY; Su, CC; Yang, HJ; Yang, TH, 2018) |
| "The effect of 5-HTP administration on seizure-induced mortality evoked by acoustic stimulation or by PTZ was investigated in DBA/1 mice." | 1.43 | 5-Hydroxytryptophan, a precursor for serotonin synthesis, reduces seizure-induced respiratory arrest. ( Cotten, JF; Feng, HJ; Xue, Q; Yang, X; Zhang, H; Zhao, H, 2016) |
| "Zymosan-induced multiple organ dysfunction syndrome (MODS) is a multifactorial pathology that involves the deterioration of function of several organs." | 1.42 | Role of Serotonin in MODS: Deficiency of Serotonin Protects Against Zymosan-Induced Multiple Organ Failure in Mice. ( Huang, Z; Liu, C; Liu, S; Liu, Y; Pang, Q; Song, S; Wu, Q; Zhang, J; Zhang, R, 2015) |
| "Although phenylketonuria (PKU) is the most common genetic cause of mental retardation, the cellular mechanisms underlying impaired brain function are still unclear." | 1.37 | 5-Hydroxytryptophan during critical postnatal period improves cognitive performances and promotes dendritic spine maturation in genetic mouse model of phenylketonuria. ( Andolina, D; Cabib, S; Conversi, D; Pascucci, T; Puglisi-Allegra, S; Trabalza, A; Ventura, R, 2011) |
| " However, the neural mechanism by which extracellular 5-HT is elevated to a toxic level for the syndrome remains to be determined." | 1.35 | Assessment of 5-hydroxytryptamine efflux in rat brain during a mild, moderate and severe serotonin-toxicity syndrome. ( Huang, X; Krishnamoorthy, S; Ma, Z; Tao, R; Vukovich, NP; Zhang, G, 2009) |
| "Alcoholism is a complex disorder involving, among others, the serotoninergic (5-HT) system, mainly regulated by 5-HT(1A) autoreceptors in the dorsal raphe nucleus." | 1.35 | Chronic voluntary ethanol intake hypersensitizes 5-HT(1A) autoreceptors in C57BL/6J mice. ( Chouchana, L; Hamon, M; Hanoun, N; Kelaï, S; Lanfumey, L; Renoir, T; Saurini, F, 2008) |
| "Pregnant women with preeclampsia have increased serotonin levels, suggesting a possible role of this amine in abnormal pregnancy." | 1.34 | Pregnant rats treated with a serotonin precursor have reduced fetal weight and lower plasma volume and kallikrein levels. ( Aranda, E; Downey, P; Giacaman, A; Mezzano, D; Romero, W; Salas, SP; Vío, CP, 2007) |
| "Pre-treatment with diazepam, 10 and 20mg/kg, and chlormethiazole, 50 and 100mg/kg, attenuated the development of hyperthermia." | 1.32 | Diazepam and chlormethiazole attenuate the development of hyperthermia in an animal model of the serotonin syndrome. ( Kato, S; Nisijima, K; Shioda, K; Takano, K; Yoshino, T, 2003) |
| "Pretreatment with risperidone (0." | 1.32 | Memantine, an NMDA antagonist, prevents the development of hyperthermia in an animal model for serotonin syndrome. ( Kato, S; Nisijima, K; Shioda, K; Takano, K; Yoshino, T, 2004) |
| "A human midgut carcinoid tumor was successfully transplanted into nude mice and propagated for five consecutive generations (30 months) with well-preserved phenotype." | 1.31 | A transplantable human carcinoid as model for somatostatin receptor-mediated and amine transporter-mediated radionuclide uptake. ( Ahlman, H; Ahrén, B; Bernhardt, P; Forssell-Aronsson, E; Johanson, V; Karlsson, S; Kölby, L; Nilsson, O; Stenman, G; Wängberg, B; Wigander, A, 2001) |
| "Pretreatment with propranolol (10 mg/kg), a 5-HT(1A) receptor antagonist as well as a beta-blocker, and dantrolene (20 mg/kg), a peripheral muscle relaxant, did not prevent the death of the animals, even though these two drugs suppressed the increase in rectal temperature to some extent." | 1.31 | Potent serotonin (5-HT)(2A) receptor antagonists completely prevent the development of hyperthermia in an animal model of the 5-HT syndrome. ( Katoh, S; Nisijima, K; Yoshino, T; Yui, K, 2001) |
| "The data suggest that this rat cardiac arrest model may be a valuable tool for investigating the pathophysiologic mechanisms of posthypoxic myoclonus and for developing new therapeutic strategies for treating the disorder." | 1.29 | Novel rat cardiac arrest model of posthypoxic myoclonus. ( Hussong, MJ; Matsumoto, RR; Schwartz, PH; Truong, DD; Wasterlain, CG, 1994) |
| "The auditory-induced myoclonus continues to worsen, reaches a peak about 2 weeks after the arrest, then declines over time to subnormal levels." | 1.29 | Novel rat cardiac arrest model of posthypoxic myoclonus. ( Hussong, MJ; Matsumoto, RR; Schwartz, PH; Truong, DD; Wasterlain, CG, 1994) |
| "Indoleamine-induced myoclonus in guinea pigs is a specific model of brainstem 5-HT function that can be used to characterize the indoleamine systems initiating myoclonus." | 1.27 | 5-HT-mediated myoclonus in the guinea pig as a model of brainstem 5-HT and tryptamine receptor action. ( Jenner, P; Luscombe, G; Marsden, CD, 1986) |
| "p,p'-DDT-induced myoclonus in mice has been proposed as a model of stimulus-sensitive action myoclonus responsive to L-5-HTP and clonazepam treatment." | 1.27 | p,p'-DDT-induced myoclonus in the rat and its application as an animal model of 5-HT-sensitive action myoclonus. ( Jenner, P; Marsden, CD; Pratt, JA; Rothwell, J, 1986) |
| "Pretreatment with desipramine (2." | 1.27 | Blockade of a 5-hydroxytryptophan-induced animal model of depression with a potent and selective 5-HT2 receptor antagonist (LY53857). ( Aprison, MH; Fuller, RW; Hingtgen, JN; Mason, NR, 1985) |
| " Chronic administration of trazodone (2 mg/kg trazodone/day) also resulted in a significant blockade of the 5-HTP effect (75%)." | 1.27 | Postsynaptic serotonergic blockade following chronic antidepressive treatment with trazodone in an animal model of depression. ( Aprison, MH; Hendrie, HC; Hingtgen, JN, 1984) |
| "We have investigated the effect of pyridoxine deficiency on aromatic L-amino acid decarboxylase (AADC) using both dihydroxyphenylalanine (DOPA) and 5-hydroxytryptophan (5HTP) as substrates in the rat brain." | 1.27 | Effect of pyridoxine deficiency on aromatic L-amino acid decarboxylase in adult rat brain. ( Dakshinamurti, K; Siow, YL, 1985) |
| "The syndrome was not seen after thioridazine (3-7 mg/kg)." | 1.26 | Acute dystonia as an idiosyncratic response to neuroleptics in baboons. ( Anlezark, GM; Marsden, CD; Meldrum, BS, 1977) |
| "In monkeys with resting tremor, the administration of DL-5-HTP (5-hydroxytryptophan) or of DL-DOPA (3,4-dihydroxyphenylalanine) relieves the tremor, but the simultaneous administration of DL-5-HTP or DL-DOPA and atropine results in a much more pronounced relief." | 1.25 | The effects of centrally acting drugs on tremor in monkeys with mesencephalic lesions. ( Anagnoste, B; Battista, AF; Goldstein, M; Nakatani, S, 1969) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 33 (41.77) | 18.7374 |
| 1990's | 4 (5.06) | 18.2507 |
| 2000's | 17 (21.52) | 29.6817 |
| 2010's | 22 (27.85) | 24.3611 |
| 2020's | 3 (3.80) | 2.80 |
| Authors | Studies |
|---|---|
| Abrams, RPM | 1 |
| Yasgar, A | 1 |
| Teramoto, T | 1 |
| Lee, MH | 1 |
| Dorjsuren, D | 1 |
| Eastman, RT | 1 |
| Malik, N | 1 |
| Zakharov, AV | 1 |
| Li, W | 1 |
| Bachani, M | 1 |
| Brimacombe, K | 1 |
| Steiner, JP | 1 |
| Hall, MD | 1 |
| Balasubramanian, A | 1 |
| Jadhav, A | 1 |
| Padmanabhan, R | 1 |
| Simeonov, A | 1 |
| Nath, A | 1 |
| Ahn, Y | 1 |
| Hong, KB | 1 |
| Kim, S | 1 |
| Suh, HJ | 1 |
| Jo, K | 1 |
| Wang, ZJ | 1 |
| Chen, LH | 1 |
| Xu, J | 1 |
| Xu, QX | 1 |
| Xu, W | 1 |
| Yang, XW | 1 |
| Stephen, DS | 1 |
| Abraham, A | 1 |
| Hsu, PY | 1 |
| Yang, HJ | 1 |
| Yang, TH | 1 |
| Su, CC | 1 |
| Klein, C | 1 |
| Roussel, G | 1 |
| Brun, S | 1 |
| Rusu, C | 1 |
| Patte-Mensah, C | 1 |
| Maitre, M | 1 |
| Mensah-Nyagan, AG | 1 |
| Israelyan, N | 1 |
| Del Colle, A | 1 |
| Li, Z | 1 |
| Park, Y | 1 |
| Xing, A | 1 |
| Jacobsen, JPR | 1 |
| Luna, RA | 1 |
| Jensen, DD | 1 |
| Madra, M | 1 |
| Saurman, V | 1 |
| Rahim, R | 1 |
| Latorre, R | 1 |
| Law, K | 1 |
| Carson, W | 1 |
| Bunnett, NW | 1 |
| Caron, MG | 1 |
| Margolis, KG | 1 |
| Tronci, E | 1 |
| Lisci, C | 1 |
| Stancampiano, R | 1 |
| Fidalgo, C | 1 |
| Collu, M | 1 |
| Devoto, P | 1 |
| Carta, M | 1 |
| O'Brien, FE | 1 |
| O'Connor, RM | 1 |
| Clarke, G | 1 |
| Donovan, MD | 1 |
| Dinan, TG | 1 |
| Griffin, BT | 1 |
| Cryan, JF | 1 |
| Jensen, JB | 1 |
| du Jardin, KG | 1 |
| Song, D | 1 |
| Budac, D | 1 |
| Smagin, G | 1 |
| Sanchez, C | 2 |
| Pehrson, AL | 1 |
| Zhang, J | 1 |
| Pang, Q | 1 |
| Song, S | 1 |
| Zhang, R | 1 |
| Liu, S | 1 |
| Huang, Z | 1 |
| Wu, Q | 1 |
| Liu, Y | 1 |
| Liu, C | 1 |
| Nau, F | 1 |
| Miller, J | 1 |
| Saravia, J | 1 |
| Ahlert, T | 1 |
| Yu, B | 1 |
| Happel, KI | 1 |
| Cormier, SA | 1 |
| Nichols, CD | 1 |
| Zhao, X | 1 |
| Wang, C | 1 |
| Cui, WG | 1 |
| Ma, Q | 1 |
| Zhou, WH | 1 |
| Shao, YY | 1 |
| Huang, J | 1 |
| Ma, YR | 1 |
| Han, M | 1 |
| Ma, K | 1 |
| Qin, HY | 1 |
| Rao, Z | 1 |
| Wu, XA | 1 |
| Carli, M | 1 |
| Kostoula, C | 1 |
| Sacchetti, G | 1 |
| Mainolfi, P | 1 |
| Anastasia, A | 1 |
| Villani, C | 1 |
| Invernizzi, RW | 1 |
| Eskelund, A | 1 |
| Budac, DP | 1 |
| Elfving, B | 1 |
| Wegener, G | 1 |
| Goeden, N | 1 |
| Velasquez, J | 1 |
| Arnold, KA | 1 |
| Chan, Y | 1 |
| Lund, BT | 1 |
| Anderson, GM | 1 |
| Bonnin, A | 1 |
| Zhang, H | 1 |
| Zhao, H | 1 |
| Yang, X | 1 |
| Xue, Q | 1 |
| Cotten, JF | 1 |
| Feng, HJ | 1 |
| Chauvel, V | 1 |
| Multon, S | 1 |
| Schoenen, J | 1 |
| Kelaï, S | 1 |
| Renoir, T | 1 |
| Chouchana, L | 1 |
| Saurini, F | 1 |
| Hanoun, N | 1 |
| Hamon, M | 1 |
| Lanfumey, L | 1 |
| Zhang, G | 2 |
| Krishnamoorthy, S | 1 |
| Ma, Z | 1 |
| Vukovich, NP | 1 |
| Huang, X | 1 |
| Tao, R | 1 |
| Pascucci, T | 3 |
| Andolina, D | 2 |
| Mela, IL | 1 |
| Conversi, D | 2 |
| Latagliata, C | 1 |
| Ventura, R | 3 |
| Puglisi-Allegra, S | 3 |
| Cabib, S | 3 |
| Hayashi, Y | 1 |
| Jacob-Vadakot, S | 1 |
| Dugan, EA | 1 |
| McBride, S | 1 |
| Olexa, R | 1 |
| Simansky, K | 1 |
| Murray, M | 1 |
| Shumsky, JS | 1 |
| Trabalza, A | 1 |
| Mahesh, R | 1 |
| Jindal, A | 1 |
| Gautam, B | 1 |
| Bhatt, S | 1 |
| Pandey, D | 1 |
| Blazevic, S | 1 |
| Colic, L | 1 |
| Culig, L | 1 |
| Hranilovic, D | 1 |
| Abdala-Valencia, H | 1 |
| Berdnikovs, S | 1 |
| McCary, CA | 1 |
| Urick, D | 1 |
| Mahadevia, R | 1 |
| Marchese, ME | 1 |
| Swartz, K | 1 |
| Wright, L | 1 |
| Mutlu, GM | 1 |
| Cook-Mills, JM | 1 |
| Shioda, K | 3 |
| Nisijima, K | 5 |
| Kasai, M | 1 |
| Yoshino, T | 5 |
| Kato, S | 3 |
| Takano, K | 2 |
| Llambías, EB | 1 |
| Aldonatti, C | 1 |
| San Martín de Viale, LC | 1 |
| Turner, BJ | 1 |
| Lopes, EC | 1 |
| Cheema, SS | 1 |
| Honda, M | 1 |
| Tanabe, M | 1 |
| Ono, H | 1 |
| Rojas-Corrales, MO | 1 |
| Gibert-Rahola, J | 1 |
| Mico, JA | 1 |
| Bechtholt, AJ | 1 |
| Hill, TE | 1 |
| Lucki, I | 1 |
| Salas, SP | 1 |
| Giacaman, A | 1 |
| Romero, W | 1 |
| Downey, P | 1 |
| Aranda, E | 1 |
| Mezzano, D | 1 |
| Vío, CP | 1 |
| Squires, LN | 1 |
| Talbot, KN | 1 |
| Rubakhin, SS | 1 |
| Sweedler, JV | 1 |
| Hughes, ZA | 1 |
| Liu, F | 1 |
| Platt, BJ | 1 |
| Dwyer, JM | 1 |
| Pulicicchio, CM | 1 |
| Schechter, LE | 1 |
| Rosenzweig-Lipson, S | 1 |
| Day, M | 1 |
| Killam, EK | 1 |
| Killam, KF | 1 |
| Willner, P | 1 |
| Hingtgen, JN | 6 |
| Hendrie, HC | 1 |
| Aprison, MH | 6 |
| Nagayama, H | 3 |
| Kawanishi, K | 1 |
| Hashimoto, Y | 1 |
| Fujiwara, M | 1 |
| Kataoka, Y | 1 |
| Ueki, S | 1 |
| Delbarre, G | 1 |
| Delbarre, B | 1 |
| Casset-Senon, D | 1 |
| Yan, QS | 1 |
| Jobe, PC | 1 |
| Dailey, JW | 1 |
| Truong, DD | 1 |
| Matsumoto, RR | 1 |
| Schwartz, PH | 1 |
| Hussong, MJ | 1 |
| Wasterlain, CG | 1 |
| Costall, B | 1 |
| Naylor, RJ | 1 |
| Bourin, M | 1 |
| Hascoet, M | 1 |
| Deguiral, P | 1 |
| Ishiguro, T | 1 |
| Kölby, L | 1 |
| Bernhardt, P | 1 |
| Ahlman, H | 1 |
| Wängberg, B | 1 |
| Johanson, V | 1 |
| Wigander, A | 1 |
| Forssell-Aronsson, E | 1 |
| Karlsson, S | 1 |
| Ahrén, B | 1 |
| Stenman, G | 1 |
| Nilsson, O | 1 |
| Yui, K | 1 |
| Katoh, S | 1 |
| Joyeux, H | 1 |
| Joyeux, A | 1 |
| Raoux, P | 1 |
| Brissac, C | 1 |
| Blanc, F | 1 |
| Solassol, C | 1 |
| Poitou, P | 1 |
| Boulu, R | 1 |
| Bohuon, C | 1 |
| Tachiki, KH | 1 |
| Takagi, A | 1 |
| Tateishi, T | 1 |
| Kido, A | 1 |
| Nishiwaki, K | 1 |
| Nakamura, E | 1 |
| Takahashi, R | 1 |
| Borison, RL | 1 |
| Havdala, HS | 1 |
| Diamond, BI | 1 |
| Meldrum, BS | 1 |
| Anlezark, GM | 1 |
| Marsden, CD | 3 |
| Luscombe, G | 1 |
| Jenner, P | 2 |
| Pratt, JA | 1 |
| Rothwell, J | 1 |
| Bartelmess, P | 1 |
| Bengtsson, F | 1 |
| Nobin, A | 1 |
| Jeppsson, B | 1 |
| Herlin, P | 1 |
| Bugge, M | 1 |
| Colpaert, FC | 1 |
| Meert, TF | 1 |
| Niemegeers, CJ | 1 |
| Janssen, PA | 1 |
| Pranzatelli, MR | 1 |
| Snodgrass, SR | 1 |
| Chapman, AG | 1 |
| Chen, CS | 1 |
| Shum, AY | 1 |
| Hsu, SC | 1 |
| Chen, CF | 1 |
| Bo, P | 1 |
| Camana, C | 1 |
| Curti, M | 1 |
| Fussi, F | 1 |
| Giorgetti, A | 1 |
| Savoldi, F | 1 |
| Carvey, P | 1 |
| Paulseth, JE | 1 |
| Goetz, CG | 1 |
| Klawans, HL | 1 |
| Wolfson, LI | 1 |
| Thal, LJ | 1 |
| Brown, LL | 1 |
| Leander, JD | 1 |
| Brugge, KL | 1 |
| Fuller, RW | 1 |
| Mason, NR | 1 |
| Siow, YL | 1 |
| Dakshinamurti, K | 1 |
| Babington, RG | 1 |
| Wedeking, PW | 1 |
| Goldstein, M | 3 |
| Anagnoste, B | 3 |
| Battista, AF | 3 |
| Nakatani, S | 3 |
| Ogawa, M | 1 |
| Wardle, EN | 1 |
| Collier, HO | 1 |
| Francis, DL | 1 |
| Henderson, G | 1 |
| Schneider, C | 1 |
4 reviews available for 5-hydroxytryptophan and Disease Models, Animal
| Article | Year |
|---|---|
The validity of animal models of depression.
Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Behavior, Animal; Circadian Rhythm; Depressive Disorder; | 1984 |
The pharmacology of the 5-HT4 receptor.
Topics: 4-Aminobenzoic Acid; 5-Hydroxytryptophan; Animals; Anxiety; Arousal; Brain; Diazepam; Disease Models | 1993 |
The pharmacology of myoclonus.
Topics: 5-Hydroxytryptophan; Adrenocorticotropic Hormone; Animals; Anticonvulsants; Benzodiazepines; Brain; | 1985 |
Valproate and myoclonus.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Aspartic Acid; Clonazepam; DDT; Disease Models, Animal; F | 1986 |
75 other studies available for 5-hydroxytryptophan and Disease Models, Animal
| Article | Year |
|---|---|
Therapeutic candidates for the Zika virus identified by a high-throughput screen for Zika protease inhibitors.
Topics: Animals; Antiviral Agents; Artificial Intelligence; Chlorocebus aethiops; Disease Models, Animal; Dr | 2020 |
Changes in Locomotor Activity and Oxidative Stress-Related Factors after the Administration of an Amino Acid Mixture by Generation and Age.
Topics: 5-Hydroxytryptophan; Aging; Amino Acids; Animals; Central Nervous System; Disease Models, Animal; ga | 2021 |
Corylin ameliorates chronic ulcerative colitis via regulating the gut-brain axis and promoting 5-hydroxytryptophan production in the colon.
Topics: 5-Hydroxytryptophan; Animals; Brain-Gut Axis; Chromatography, Liquid; Colitis; Colitis, Ulcerative; | 2023 |
High-fat simple carbohydrate (HFSC) diet impairs hypothalamic and corpus striatal serotonergic metabolic pathway in metabolic syndrome (MetS) induced C57BL/6J mice.
Topics: 5-Hydroxytryptophan; Animals; Corpus Striatum; Diet, High-Fat; Dietary Carbohydrates; Disease Models | 2019 |
5-hydroxytryptophan attenuates imiquimod-induced psoriasiform dermatitis probably through inhibition of IL-17A production and keratinocyte activation.
Topics: 5-Hydroxytryptophan; Animals; CD4-Positive T-Lymphocytes; Cell Differentiation; Cell Line; Cyclooxyg | 2018 |
5-HIAA induces neprilysin to ameliorate pathophysiology and symptoms in a mouse model for Alzheimer's disease.
Topics: 5-Hydroxytryptophan; Alzheimer Disease; Amyloid beta-Peptides; Amyloid beta-Protein Precursor; Anima | 2018 |
Effects of Serotonin and Slow-Release 5-Hydroxytryptophan on Gastrointestinal Motility in a Mouse Model of Depression.
Topics: 5-Hydroxytryptophan; Animals; Constipation; Delayed-Action Preparations; Depression; Disease Models, | 2019 |
5-Hydroxy-tryptophan for the treatment of L-DOPA-induced dyskinesia in the rat Parkinson's disease model.
Topics: 5-Hydroxytryptophan; Adrenergic Agents; Animals; Caudate Nucleus; Disease Models, Animal; Dopamine; | 2013 |
The P-glycoprotein inhibitor cyclosporin A differentially influences behavioural and neurochemical responses to the antidepressant escitalopram.
Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Behavior, Animal; Brain; Citalopram; Cyclospori | 2014 |
Vortioxetine, but not escitalopram or duloxetine, reverses memory impairment induced by central 5-HT depletion in rats: evidence for direct 5-HT receptor modulation.
Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Citalopram; Disease Models, Animal; Dose-Response Relations | 2014 |
Role of Serotonin in MODS: Deficiency of Serotonin Protects Against Zymosan-Induced Multiple Organ Failure in Mice.
Topics: 5-Hydroxytryptophan; Animals; Cytokines; Disease Models, Animal; Enzyme Inhibitors; Fenclonine; Male | 2015 |
Serotonin 5-HT₂ receptor activation prevents allergic asthma in a mouse model.
Topics: 5-Hydroxytryptophan; Amphetamines; Animals; Anti-Inflammatory Agents; Asthma; Bronchial Hyperreactiv | 2015 |
Fisetin exerts antihyperalgesic effect in a mouse model of neuropathic pain: engagement of spinal serotonergic system.
Topics: 5-Hydroxytryptophan; Analgesics; Animals; Behavior, Animal; Biogenic Monoamines; Disease Models, Ani | 2015 |
Serum serotonin reduced the expression of hepatic transporter Mrp2 and P-gp via regulating nuclear receptor CAR in PI-IBS rats.
Topics: 5-Hydroxytryptophan; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding C | 2015 |
Tph2 gene deletion enhances amphetamine-induced hypermotility: effect of 5-HT restoration and role of striatal noradrenaline release.
Topics: 5-Hydroxytryptophan; Adrenergic Uptake Inhibitors; Amphetamine; Animals; Carbidopa; Corpus Striatum; | 2015 |
Female Flinders Sensitive Line rats show estrous cycle-independent depression-like behavior and altered tryptophan metabolism.
Topics: 5-Hydroxytryptophan; Animals; Anxiety; Brain; Depressive Disorder; Disease Models, Animal; Estrous C | 2016 |
Maternal Inflammation Disrupts Fetal Neurodevelopment via Increased Placental Output of Serotonin to the Fetal Brain.
Topics: 5-Hydroxytryptophan; Animals; Brain; Cytokines; Disease Models, Animal; Female; Fenclonine; Fetal De | 2016 |
5-Hydroxytryptophan, a precursor for serotonin synthesis, reduces seizure-induced respiratory arrest.
Topics: 5-Hydroxytryptophan; Acoustic Stimulation; Animals; Brain Stem; Disease Models, Animal; Dose-Respons | 2016 |
Estrogen-dependent effects of 5-hydroxytryptophan on cortical spreading depression in rat: Modelling the serotonin-ovarian hormone interaction in migraine aura.
Topics: 5-Hydroxytryptophan; Animals; Cortical Spreading Depression; Disease Models, Animal; Estrogens; Fema | 2018 |
Chronic voluntary ethanol intake hypersensitizes 5-HT(1A) autoreceptors in C57BL/6J mice.
Topics: 5-Hydroxytryptophan; Action Potentials; Alcohol Drinking; Alcoholism; Animals; Behavior, Animal; Bod | 2008 |
Assessment of 5-hydroxytryptamine efflux in rat brain during a mild, moderate and severe serotonin-toxicity syndrome.
Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Body Temperature; Clorgyline; Cyproheptadine; D | 2009 |
5-Hydroxytryptophan rescues serotonin response to stress in prefrontal cortex of hyperphenylalaninaemic mice.
Topics: 5-Hydroxytryptophan; Analysis of Variance; Animals; Antidepressive Agents, Second-Generation; Diet, | 2009 |
5-HT precursor loading, but not 5-HT receptor agonists, increases motor function after spinal cord contusion in adult rats.
Topics: 5-Hydroxytryptophan; Animals; Carbidopa; Cervical Vertebrae; Disease Models, Animal; Dose-Response R | 2010 |
5-Hydroxytryptophan during critical postnatal period improves cognitive performances and promotes dendritic spine maturation in genetic mouse model of phenylketonuria.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Cognition; Cognition Disorders; Critical Period, Psy | 2011 |
Evaluation of anti-depressant-like activity of linezolid, an oxazolidinone class derivative - an investigation using behavioral tests battery of depression.
Topics: 5-Hydroxytryptophan; Acetamides; Animals; Antidepressive Agents; Behavior; Depression; Disease Model | 2011 |
Anxiety-like behavior and cognitive flexibility in adult rats perinatally exposed to increased serotonin concentrations.
Topics: 5-Hydroxytryptophan; Analysis of Variance; Animals; Antidepressive Agents, Second-Generation; Anxiet | 2012 |
Inhibition of allergic inflammation by supplementation with 5-hydroxytryptophan.
Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents, Second-Generation; Asthma; Cell Adhesion Molecu | 2012 |
Risperidone attenuates the increase of extracellular nitric oxide and glutamate levels in serotonin syndrome animal models.
Topics: 5-Hydroxytryptophan; Animals; Brain; Clorgyline; Disease Models, Animal; Fluoxetine; Glutamic Acid; | 2012 |
Deficits in brain serotonin synthesis in a genetic mouse model of phenylketonuria.
Topics: 5-Hydroxytryptophan; Animals; Blood-Brain Barrier; Brain; Disease Models, Animal; Female; Genotype; | 2002 |
Diazepam and chlormethiazole attenuate the development of hyperthermia in an animal model of the serotonin syndrome.
Topics: 5-Hydroxytryptophan; Animals; Body Temperature; Brain; Chlormethiazole; Clorgyline; Diazepam; Diseas | 2003 |
Tryptophan metabolism via serotonin in rats with hexachlorobenzene experimental porphyria.
Topics: 5-Hydroxytryptophan; Animals; Brain; Chromatography, High Pressure Liquid; Digestive System; Disease | 2003 |
The serotonin precursor 5-hydroxytryptophan delays neuromuscular disease in murine familial amyotrophic lateral sclerosis.
Topics: 5-Hydroxytryptophan; Aging; Alanine; Amyotrophic Lateral Sclerosis; Animals; Animals, Newborn; Body | 2003 |
Memantine, an NMDA antagonist, prevents the development of hyperthermia in an animal model for serotonin syndrome.
Topics: 5-Hydroxytryptophan; Animals; Body Temperature; Clorgyline; Disease Models, Animal; Dizocilpine Male | 2004 |
Spinal cord injury-specific depression of monosynaptic spinal reflex transmission by l-5-hydroxytryptophan results from loss of the 5-HT uptake system and not 5-HT receptor supersensitivity.
Topics: 5-Hydroxytryptophan; Analysis of Variance; Animals; Antidepressive Agents, Second-Generation; Diseas | 2006 |
Role of atypical opiates in OCD. Experimental approach through the study of 5-HT(2A/C) receptor-mediated behavior.
Topics: 5-Hydroxytryptophan; Analgesics, Opioid; Animals; Clozapine; Desipramine; Disease Models, Animal; Do | 2007 |
Anxiolytic effect of serotonin depletion in the novelty-induced hypophagia test.
Topics: 5-Hydroxytryptophan; Analysis of Variance; Animals; Anti-Anxiety Agents; Anxiety; Behavior, Animal; | 2007 |
Pregnant rats treated with a serotonin precursor have reduced fetal weight and lower plasma volume and kallikrein levels.
Topics: 5-Hydroxytryptophan; Aldosterone; Animals; Blood Pressure; Creatinine; Disease Models, Animal; Femal | 2007 |
Serotonin catabolism in the central and enteric nervous systems of rats upon induction of serotonin syndrome.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Brain; Central Nervous System; Disease Models, Anima | 2007 |
WAY-200070, a selective agonist of estrogen receptor beta as a potential novel anxiolytic/antidepressant agent.
Topics: 5-Hydroxytryptophan; Animals; Anti-Anxiety Agents; Antidepressive Agents; Anxiety; Behavior, Animal; | 2008 |
Evidence for neurotransmitter abnormalities related to seizure activity in the epileptic baboon.
Topics: 5-Hydroxytryptophan; Acetylcholine; Amphetamine; Animals; Brain; Disease Models, Animal; Dopamine; E | 1984 |
Postsynaptic serotonergic blockade following chronic antidepressive treatment with trazodone in an animal model of depression.
Topics: 5-Hydroxytryptophan; Amitriptyline; Animals; Depression; Disease Models, Animal; Humans; Male; Methy | 1984 |
Pre- and postsynaptic serotonergic manipulations in an animal model of depression.
Topics: 5-Hydroxytryptophan; Amitriptyline; Animals; Depression; Disease Models, Animal; Drug Synergism; Flu | 1980 |
Postsynaptic action by four antidepressive drugs in an animal model of depression.
Topics: 5-Hydroxytryptophan; Amitriptyline; Animals; Antidepressive Agents; Behavior, Animal; Depression; Di | 1981 |
Pharmacological characteristics of abnormal behavior induced by harmine with special reference to tremor in mice.
Topics: 5-Hydroxytryptophan; Alkaloids; Animals; Antidepressive Agents; Behavior, Animal; Diazepam; Disease | 1981 |
Hypersensitive serotonergic receptors: a new hypothesis for one subgroup of unipolar depression derived from an animal model.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Brain; Columbidae; Depressive Disorder; Disease Mode | 1981 |
[The use of the Mongolian gerbil as a model for cerebrovascular involvement].
Topics: 5-Hydroxytryptophan; Animals; Brain Ischemia; Circle of Willis; Disease Models, Animal; Dose-Respons | 1980 |
Evidence that a serotonergic mechanism is involved in the anticonvulsant effect of fluoxetine in genetically epilepsy-prone rats.
Topics: 5-Hydroxytryptophan; Animals; Anticonvulsants; Disease Models, Animal; Drug Synergism; Epilepsy; Fem | 1994 |
Novel rat cardiac arrest model of posthypoxic myoclonus.
Topics: 5-Hydroxytryptophan; Acoustic Stimulation; Animals; Anticonvulsants; Clonazepam; Disease Models, Ani | 1994 |
5-HTP induced diarrhea as a carcinoid syndrome model in mice?
Topics: 5-Hydroxytryptophan; Animals; Benserazide; Carcinoid Tumor; Defecation; Diarrhea; Disease Models, An | 1996 |
Risperidone counteracts lethality in an animal model of the serotonin syndrome.
Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Body Temperature; Clorgyline; Disease Models, A | 2000 |
A transplantable human carcinoid as model for somatostatin receptor-mediated and amine transporter-mediated radionuclide uptake.
Topics: 3-Iodobenzylguanidine; 5-Hydroxytryptophan; Animals; Biogenic Amines; Calcium; Carcinoid Tumor; Carr | 2001 |
Potent serotonin (5-HT)(2A) receptor antagonists completely prevent the development of hyperthermia in an animal model of the 5-HT syndrome.
Topics: 5-Hydroxytryptophan; Animals; Anterior Hypothalamic Nucleus; Antidepressive Agents; Body Temperature | 2001 |
[Metabolic disorders in experimental hepatic insufficiency and parenteral feeding].
Topics: 5-Hydroxytryptophan; Amino Acids; Ammonia; Animals; Blood Coagulation; Blood Transfusion; Choline; D | 1977 |
Effect of lithium and other drugs on the amphetamine chlordiazeposice hyperactivity in mice.
Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Bipolar Disorder; Brain Chemistry; Chlordiazepoxide; Dise | 1975 |
Animal model of depression. III. Mechanism of action of tetrabenazine.
Topics: 5-Hydroxytryptophan; Animals; Brain; Brain Chemistry; Depression; Disease Models, Animal; Dopamine; | 1978 |
A new animal model for schizophrenia: cholinergic and serotonergic modulation.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Dextroamphetamine; Disease Models, Animal; Dose-Resp | 1978 |
Acute dystonia as an idiosyncratic response to neuroleptics in baboons.
Topics: 5-Hydroxytryptophan; Acute Disease; Animals; Apomorphine; Corpus Striatum; Disease Models, Animal; H | 1977 |
5-HT-mediated myoclonus in the guinea pig as a model of brainstem 5-HT and tryptamine receptor action.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Brain; Carbidopa; Disease Models, Animal; Guinea Pig | 1986 |
p,p'-DDT-induced myoclonus in the rat and its application as an animal model of 5-HT-sensitive action myoclonus.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Brain; Clonazepam; DDT; Disease Models, Animal; Elec | 1986 |
The effect of blood ingestion on brain serotonin synthesis in portacaval-shunted rats.
Topics: 5-Hydroxytryptophan; Amino Acids; Ammonia; Animals; Blood; Brain; Disease Models, Animal; Explorator | 1987 |
Behavioral and 5-HT antagonist effects of ritanserin: a pure and selective antagonist of LSD discrimination in rat.
Topics: 5-Hydroxytryptophan; Animals; Anti-Anxiety Agents; Anxiety; Chlordiazepoxide; Diazepam; Disease Mode | 1985 |
Turnover of central biogenic amines in two-kidney, one-clip renal hypertensive rats.
Topics: 5-Hydroxytryptophan; Animals; Biogenic Amines; Blood Pressure; Brain; Chromatography, High Pressure | 1986 |
Experimental study on central effects of carboxyethyl-gamma-aminobutyric acid (CEGABA).
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Brain; Disease Models, Animal; Electroencephalograph | 1988 |
L-5-HTP-induced myoclonic jumping behavior in guinea pigs: an update.
Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Bromocriptine; Clonazepam; Disease Models, Animal; Guinea | 1986 |
Serotonin models of myoclonus in the guinea pig and rat.
Topics: 5-Hydroxytryptophan; Animals; Autoradiography; Behavior, Animal; Deoxyglucose; Disease Models, Anima | 1986 |
Peripheral action of serotonin as a model of depression.
Topics: 5-Hydroxytryptophan; Amidines; Animals; Blood-Brain Barrier; Conditioning, Operant; Depression, Chem | 1986 |
Potentiated 5-hydroxytryptophan induced response suppression in rats following chronic reserpine.
Topics: 5-Hydroxytryptophan; Animals; Depression; Disease Models, Animal; Drug Synergism; Male; Rats; Rats, | 1987 |
Blockade of a 5-hydroxytryptophan-induced animal model of depression with a potent and selective 5-HT2 receptor antagonist (LY53857).
Topics: 5-Hydroxytryptophan; Animals; Cerebral Cortex; Conditioning, Operant; Depression; Desipramine; Disea | 1985 |
Effect of pyridoxine deficiency on aromatic L-amino acid decarboxylase in adult rat brain.
Topics: 5-Hydroxytryptophan; Animals; Aromatic-L-Amino-Acid Decarboxylases; Brain; Brain Chemistry; Disease | 1985 |
The influence of cinanserin and selected pharmacologic agents on experimental allergic encephalomyelitis (EAE).
Topics: 5-Hydroxytryptophan; Amphetamine; Anilides; Animals; Azathioprine; Body Weight; Chlorpheniramine; Ci | 1971 |
Biochemical aspects of experimentally induced parkinsonism.
Topics: 5-Hydroxytryptophan; Amines; Amino Acids; Animals; Antiparkinson Agents; Apomorphine; Basal Ganglia; | 1972 |
The relevance of intravascular coagulation to pre-eclampsia.
Topics: 5-Hydroxytryptophan; Abruptio Placentae; Animals; Blood Coagulation Factors; Desoxycorticosterone; D | 1973 |
Quasi morphine-abstinence syndrome.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Delayed-Action Preparations; Disease Models, Animal; | 1974 |
The effects of centrally acting drugs on tremor in monkeys with mesencephalic lesions.
Topics: 5-Hydroxytryptophan; Animals; Atropine; Dihydroxyphenylalanine; Disease Models, Animal; Drug Synergi | 1969 |
Drug-induced relief of experimental tremor in monkeys.
Topics: 5-Hydroxytryptophan; Animals; Basal Ganglia; Brain Stem; Dihydroxyphenylalanine; Disease Models, Ani | 1970 |