5-hydroxytryptophan has been researched along with Diarrhea in 16 studies
5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.
Diarrhea: An increased liquidity or decreased consistency of FECES, such as running stool. Fecal consistency is related to the ratio of water-holding capacity of insoluble solids to total water, rather than the amount of water present. Diarrhea is not hyperdefecation or increased fecal weight.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To study differences in the visceral sensitivity of the colonic mucosa between patients with diarrhea-predominant irritable bowel syndrome (IBS-D) and those with ulcerative colitis (UC) in remission and to relate these differences with changes in the 5-hydroxytryptophan (5-HT) signaling pathway." | 7.83 | Comparison of 5-hydroxytryptophan signaling pathway characteristics in diarrhea-predominant irritable bowel syndrome and ulcerative colitis. ( Chi, HG; Huang, SG; Lv, RX; Ye, H; Yu, FY; Zhang, HY; Zheng, XB; Zou, Y, 2016) |
| "The potential role of endogenous opiates in the mediation of the diarrheal actions of prostaglandin-F2 alpha (PGF2 alpha), 5-hydroxytryptophan (5-HTP) and methacholine was investigated." | 7.66 | Naloxone reversal of drug-induced diarrhea in mice. ( Bertermann, RE; Dajani, EZ; Roge, EA; Schweingruber, FL; Woods, EM, 1979) |
| " The three diarrheal agents, administered intraperitoneally, showed dose-dependent and parallel dose-response curves with the following order of decreasing potency: PGF2 alpha, methacholine and 5-HTP." | 5.26 | Naloxone reversal of drug-induced diarrhea in mice. ( Bertermann, RE; Dajani, EZ; Roge, EA; Schweingruber, FL; Woods, EM, 1979) |
| "To study differences in the visceral sensitivity of the colonic mucosa between patients with diarrhea-predominant irritable bowel syndrome (IBS-D) and those with ulcerative colitis (UC) in remission and to relate these differences with changes in the 5-hydroxytryptophan (5-HT) signaling pathway." | 3.83 | Comparison of 5-hydroxytryptophan signaling pathway characteristics in diarrhea-predominant irritable bowel syndrome and ulcerative colitis. ( Chi, HG; Huang, SG; Lv, RX; Ye, H; Yu, FY; Zhang, HY; Zheng, XB; Zou, Y, 2016) |
| " PYY suppression of intraperitoneal 5-hydroxytryptophan induced FPO and diarrhea was blocked by the Y(2) antagonist, BIIE0246, injected intraperitoneally and mimicked by PYY(3-36), but not [Leu(31),Pro(34)]NPY." | 3.76 | Peripheral peptide YY inhibits propulsive colonic motor function through Y2 receptor in conscious mice. ( Gourcerol, G; Larauche, M; Million, M; Taché, Y; Wang, L; Wu, SV; Yuan, PQ, 2010) |
| "Our aim was to study the involvement of 5-hydroxytryptamine (5-HT)(3) and 5-HT(4) receptors in two models of gastrointestinal transit (GIT) in mice: the 5-hydroxytryptophan (5-HTP)-induced diarrhea and intestinal inflammation produced by an irritant agent, croton oil (CO)." | 3.71 | The involvement of 5-HT3 and 5-HT4 receptors in two models of gastrointestinal transit in mice. ( Alsasua, A; Goicoechea, C; Martín, MI; Pascual, D, 2002) |
| "The potential role of endogenous opiates in the mediation of the diarrheal actions of prostaglandin-F2 alpha (PGF2 alpha), 5-hydroxytryptophan (5-HTP) and methacholine was investigated." | 3.66 | Naloxone reversal of drug-induced diarrhea in mice. ( Bertermann, RE; Dajani, EZ; Roge, EA; Schweingruber, FL; Woods, EM, 1979) |
| "Six patients with myoclonus of varying cause were treated with L-5-hydroxytryptophan (L-5-HTP) and carbidopa." | 1.26 | Treatment of myoclonus with L-5-hydroxytryptophan and carbidopa: clinical, electrophysiological, and biochemical observations. ( Katzman, R; Sharpless, NS; Thal, LJ; Wolfson, L, 1980) |
| " The three diarrheal agents, administered intraperitoneally, showed dose-dependent and parallel dose-response curves with the following order of decreasing potency: PGF2 alpha, methacholine and 5-HTP." | 1.26 | Naloxone reversal of drug-induced diarrhea in mice. ( Bertermann, RE; Dajani, EZ; Roge, EA; Schweingruber, FL; Woods, EM, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (50.00) | 18.7374 |
| 1990's | 2 (12.50) | 18.2507 |
| 2000's | 4 (25.00) | 29.6817 |
| 2010's | 2 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yu, FY | 1 |
| Huang, SG | 1 |
| Zhang, HY | 1 |
| Ye, H | 1 |
| Chi, HG | 1 |
| Zou, Y | 1 |
| Lv, RX | 1 |
| Zheng, XB | 1 |
| Wang, L | 1 |
| Gourcerol, G | 1 |
| Yuan, PQ | 1 |
| Wu, SV | 1 |
| Million, M | 1 |
| Larauche, M | 1 |
| Taché, Y | 1 |
| Pascual, D | 2 |
| Girón, R | 1 |
| Alsasua, A | 2 |
| Benhamú, B | 1 |
| López-Rodríguez, ML | 1 |
| Martín, MI | 2 |
| Preshaw, RM | 1 |
| Leavitt, D | 1 |
| Hoag, G | 1 |
| Warrick, MW | 1 |
| Dinwiddie, WG | 1 |
| Lin, TM | 1 |
| Fuller, RW | 1 |
| Thal, LJ | 1 |
| Sharpless, NS | 1 |
| Wolfson, L | 1 |
| Katzman, R | 1 |
| Hedge, SS | 1 |
| Moy, TM | 1 |
| Perry, MR | 1 |
| Loeb, M | 1 |
| Eglen, RM | 1 |
| Bourin, M | 1 |
| Hascoet, M | 1 |
| Deguiral, P | 1 |
| Sanger, GJ | 1 |
| Yoshida, M | 1 |
| Yahyah, M | 1 |
| Kitazumi, K | 1 |
| Goicoechea, C | 1 |
| Dajani, EZ | 1 |
| Woods, EM | 1 |
| Roge, EA | 1 |
| Bertermann, RE | 1 |
| Schweingruber, FL | 1 |
| Opitz, K | 1 |
| Dreux, C | 1 |
| Bousquet, B | 1 |
| Halter, D | 1 |
| Grahame-Smith, DG | 1 |
| Dombro, RS | 1 |
| Van der Hoeven, T | 1 |
| Woolley, DW | 1 |
2 reviews available for 5-hydroxytryptophan and Diarrhea
| Article | Year |
|---|---|
Pharmacology of the carcinoid syndrome.
Topics: 5-Hydroxytryptophan; Bradykinin; Diarrhea; Drug Synergism; Humans; Kinins; Malignant Carcinoid Syndr | 1968 |
Progress report: the carcinoid syndrome.
Topics: 5-Hydroxytryptophan; Antineoplastic Agents; Bradykinin; Diarrhea; Heart Valve Diseases; Humans; Hydr | 1970 |
14 other studies available for 5-hydroxytryptophan and Diarrhea
| Article | Year |
|---|---|
Comparison of 5-hydroxytryptophan signaling pathway characteristics in diarrhea-predominant irritable bowel syndrome and ulcerative colitis.
Topics: 5-Hydroxytryptophan; Abdominal Pain; Adult; Colitis, Ulcerative; Colon; Defecation; Diarrhea; Female | 2016 |
Peripheral peptide YY inhibits propulsive colonic motor function through Y2 receptor in conscious mice.
Topics: 5-Hydroxytryptophan; Acute Disease; Animals; Arginine; Benzazepines; Bethanechol; Colon; Consciousne | 2010 |
New benzimidazole derivatives: selective and orally active 5-HT3 receptor antagonists.
Topics: 5-Hydroxytryptophan; Administration, Oral; Animals; Aza Compounds; Behavior, Animal; Benzimidazoles; | 2003 |
The dietary supplement 5-hydroxytryptophan and urinary 5-hydroxyindole acetic acid.
Topics: 5-Hydroxytryptophan; Antidepressive Agents, Second-Generation; Diarrhea; Female; Humans; Hydroxyindo | 2008 |
Antidiarrhoeal effects of quipazine and l-(m-trifluoromethylphenyl)piperazine in mice.
Topics: 5-Hydroxytryptophan; Animals; Antidiarrheals; Diarrhea; Mice; Piperazines; Quinolines; Quipazine | 1981 |
Treatment of myoclonus with L-5-hydroxytryptophan and carbidopa: clinical, electrophysiological, and biochemical observations.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Carbidopa; Clonazepam; Diarrhea; Drug Therapy, Combination; | 1980 |
Evidence for the involvement of 5-hydroxytryptamine 4 receptors in 5-hydroxytryptophan-induced diarrhea in mice.
Topics: 5-Hydroxytryptophan; Animals; Atropine; Benserazide; Benzimidazoles; Bridged Bicyclo Compounds; Brid | 1994 |
5-HTP induced diarrhea as a carcinoid syndrome model in mice?
Topics: 5-Hydroxytryptophan; Animals; Benserazide; Carcinoid Tumor; Defecation; Diarrhea; Disease Models, An | 1996 |
Increased defecation during stress or after 5-hydroxytryptophan: selective inhibition by the 5-HT(4) receptor antagonist, SB-207266.
Topics: 5-Hydroxytryptophan; Animals; Defecation; Diarrhea; Dose-Response Relationship, Drug; Fasting; Indol | 2000 |
The involvement of 5-HT3 and 5-HT4 receptors in two models of gastrointestinal transit in mice.
Topics: 5-Hydroxytryptophan; Animals; Antidiarrheals; Croton Oil; Dermatologic Agents; Diarrhea; Gastrointes | 2002 |
Naloxone reversal of drug-induced diarrhea in mice.
Topics: 5-Hydroxytryptophan; Animals; Antidiarrheals; Cyproheptadine; Diarrhea; Dose-Response Relationship, | 1979 |
[Anorexigenic phenylalkylamines and serotonin metabolism].
Topics: 5-Hydroxytryptophan; Animals; Appetite Depressants; Chlorphentermine; Diarrhea; Eating; Feeding and | 1967 |
[Detection and biochemical exploration of carcinoid tumors].
Topics: 5-Hydroxytryptophan; Carcinoid Tumor; Chromatography, Ion Exchange; Diarrhea; Heart Diseases; Humans | 1974 |
An easily obtainable antiserotonin which has little effect on the brain.
Topics: 5-Hydroxytryptophan; Amines; Animals; Behavior, Animal; Biological Assay; Brain; Chemistry, Pharmace | 1965 |