5-hydroxytryptophan has been researched along with Diabetes Mellitus, Type 1 in 5 studies
5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.
Diabetes Mellitus, Type 1: A subtype of DIABETES MELLITUS that is characterized by INSULIN deficiency. It is manifested by the sudden onset of severe HYPERGLYCEMIA, rapid progression to DIABETIC KETOACIDOSIS, and DEATH unless treated with insulin. The disease may occur at any age, but is most common in childhood or adolescence.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 1 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Demine, S | 1 |
| Schulte, ML | 1 |
| Territo, PR | 1 |
| Eizirik, DL | 1 |
| Eriksson, O | 3 |
| Selvaraju, RK | 2 |
| Johansson, L | 2 |
| Eriksson, JW | 2 |
| Sundin, A | 2 |
| Antoni, G | 2 |
| Sörensen, J | 2 |
| Eriksson, B | 2 |
| Korsgren, O | 3 |
| Espes, D | 1 |
| Jansson, E | 1 |
| Lubberink, M | 1 |
| Biglarnia, AR | 1 |
| Ahlström, H | 2 |
| Carlsson, PO | 1 |
| Selvaraju, R | 1 |
| Eich, T | 1 |
| Willny, M | 1 |
| Brismar, TB | 1 |
| Carlbom, L | 1 |
| Tufvesson, G | 1 |
| Lundgren, T | 1 |
| MacIndoe, JH | 1 |
| Turkington, RW | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Open Study to Investigate Pancreatic Islet Mass by Positron Emission Tomography Using the Tracer [11C]5-hydroxytryptophane[NCT01552811] | 20 participants (Actual) | Observational | 2012-03-31 | Completed | |||
| Evaluation of the Use of 11C-5-HTP PET to Calculate βCell Mass in Clinical Islet Transplantation (DAIT CIT-09)[NCT02689479] | 8 participants (Actual) | Interventional | 2013-05-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for 5-hydroxytryptophan and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Beta Cell Imaging-From Pre-Clinical Validation to First in Man Testing.
Topics: 5-Hydroxytryptophan; Animals; Biomarkers; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Dipe | 2020 |
1 trial available for 5-hydroxytryptophan and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Positron emission tomography ligand [11C]5-hydroxy-tryptophan can be used as a surrogate marker for the human endocrine pancreas.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Aged; Carbon Radioisotopes; Diabetes Mellitus, Type 1; Femal | 2014 |
3 other studies available for 5-hydroxytryptophan and Diabetes Mellitus, Type 1
| Article | Year |
|---|---|
Quantitative imaging of serotonergic biosynthesis and degradation in the endocrine pancreas.
Topics: 5-Hydroxytryptophan; Animals; Carbon Radioisotopes; Cell Line; Diabetes Mellitus, Type 1; Humans; Is | 2014 |
Positron Emission Tomography to Assess the Outcome of Intraportal Islet Transplantation.
Topics: 5-Hydroxytryptophan; Animals; Diabetes Mellitus, Type 1; Healthy Volunteers; Humans; Islets of Lange | 2016 |
Stimulation of human prolactin secretion by intravenous infusion of L-tryptophan.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Amino Acids; Blood Glucose; Child; Chlorpromazine; Diabetes | 1973 |