5-hydroxytryptophan has been researched along with Developmental Disabilities in 5 studies
5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.
Developmental Disabilities: Disorders in which there is a delay in development based on that expected for a given age level or stage of development. These impairments or disabilities originate before age 18, may be expected to continue indefinitely, and constitute a substantial impairment. Biological and nonbiological factors are involved in these disorders. (From American Psychiatric Glossary, 6th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Treatment with 5-hydroxytryptophan (4-6 mg/kg) and carbidopa (0." | 6.70 | A novel neurodevelopmental syndrome responsive to 5-hydroxytryptophan and carbidopa. ( Abeling, N; Bergmann, C; Blau, N; Häring, M; Häusler, M; Heimann, G; Ramaekers, VT; Senderek, J; Zerres, K, 2001) |
| "Severe 6-pyruvoyl-tetrahydrobiopterin synthase deficiency is a tetrahydrobiopterin deficiency disorder that presents in infancy with developmental delay, seizures, and abnormal movements associated with hyperphenylalaninemia usually detectable by neonatal phenylketonuria screening programs." | 3.73 | 6-pyruvoyl-tetrahydropterin synthase deficiency with mild hyperphenylalaninemia. ( Blau, N; Connolly, MB; Demos, MK; Hyland, K; Lillquist, Y; Makhseed, N; Vallance, HD; Waters, PJ, 2005) |
| " Dietary restriction of phenylalanine and oral administration of amine precursors, L-dopa and 5-hydroxytryptophan had poor efficiency on epilepsy and psychomotor delay." | 3.70 | [Progressive convulsive encephalopathy: considering a abnormality of biopterin metabolism]. ( Dhondt, JL; Mikaeloff, Y; Pinton, F; Ponsot, G; Sevin, C, 1999) |
| "Treatment with 5-hydroxytryptophan (4-6 mg/kg) and carbidopa (0." | 2.70 | A novel neurodevelopmental syndrome responsive to 5-hydroxytryptophan and carbidopa. ( Abeling, N; Bergmann, C; Blau, N; Häring, M; Häusler, M; Heimann, G; Ramaekers, VT; Senderek, J; Zerres, K, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (40.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 1 (20.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dill, P | 1 |
| Wagner, M | 1 |
| Somerville, A | 1 |
| Thöny, B | 1 |
| Blau, N | 3 |
| Weber, P | 1 |
| Demos, MK | 1 |
| Waters, PJ | 1 |
| Vallance, HD | 1 |
| Lillquist, Y | 1 |
| Makhseed, N | 1 |
| Hyland, K | 2 |
| Connolly, MB | 1 |
| Maller, A | 1 |
| Milstien, S | 1 |
| Biaggioni, I | 1 |
| Butler, IJ | 1 |
| Mikaeloff, Y | 1 |
| Pinton, F | 1 |
| Sevin, C | 1 |
| Dhondt, JL | 1 |
| Ponsot, G | 1 |
| Ramaekers, VT | 1 |
| Senderek, J | 1 |
| Häusler, M | 1 |
| Häring, M | 1 |
| Abeling, N | 1 |
| Zerres, K | 1 |
| Bergmann, C | 1 |
| Heimann, G | 1 |
1 trial available for 5-hydroxytryptophan and Developmental Disabilities
| Article | Year |
|---|---|
A novel neurodevelopmental syndrome responsive to 5-hydroxytryptophan and carbidopa.
Topics: 5-Hydroxytryptophan; Abnormalities, Multiple; Carbidopa; Child; Child, Preschool; Developmental Disa | 2001 |
4 other studies available for 5-hydroxytryptophan and Developmental Disabilities
| Article | Year |
|---|---|
Child neurology: paroxysmal stiffening, upward gaze, and hypotonia: hallmarks of sepiapterin reductase deficiency.
Topics: 5-Hydroxytryptophan; Alcohol Oxidoreductases; Behavior; Benserazide; Consanguinity; Developmental Di | 2012 |
6-pyruvoyl-tetrahydropterin synthase deficiency with mild hyperphenylalaninemia.
Topics: 5-Hydroxytryptophan; Biopterins; Carbidopa; Cerebral Palsy; Child; Developmental Disabilities; Diagn | 2005 |
Aromatic L-amino acid decarboxylase deficiency: clinical features, diagnosis, and treatment of a second family.
Topics: 5-Hydroxytryptophan; Amino Acids, Cyclic; Aromatic-L-Amino-Acid Decarboxylases; Biogenic Monoamines; | 1997 |
[Progressive convulsive encephalopathy: considering a abnormality of biopterin metabolism].
Topics: 5-Hydroxytryptophan; Algeria; Anticonvulsants; Biopterins; Brain; Child, Preschool; Consanguinity; D | 1999 |