5-hydroxytryptophan has been researched along with Depression, Endogenous in 78 studies
5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Serum cortisol levels were significantly increased following administration of 5-hydroxytryptophan (5-HTP), 200 mg orally, to patients with affective disorders." | 9.05 | Effect of 5-hydroxytryptophan on serum cortisol levels in major affective disorders. III. Effect of antidepressants and lithium carbonate. ( Goodnick, P; Lowy, M; Meltzer, HY; Perline, R; Robertson, A, 1984) |
| "Serum cortisol levels were significantly higher after administration of 5-hydroxytryptophan (5-HTP), 200 mg orally, in unmedicated patients with affective disorders than in controls." | 9.05 | Effect of 5-hydroxytryptophan on serum cortisol levels in major affective disorders. II. Relation to suicide, psychosis, and depressive symptoms. ( Lowy, M; Meltzer, HY; Perline, R; Robertson, A; Tricou, BJ, 1984) |
| "A patient suffering from endogenous depression was treated with mianserin and developed agranulocytosis." | 7.68 | [Mianserin agranulocytosis followed by oxitriptan eosinophilia]. ( García, C, 1992) |
| "A patient suffering from endogenous depression was treated with mianserin and developed agranulocytosis." | 5.28 | [Mianserin agranulocytosis followed by oxitriptan eosinophilia]. ( García, C, 1992) |
| "Serum cortisol levels were significantly increased following administration of 5-hydroxytryptophan (5-HTP), 200 mg orally, to patients with affective disorders." | 5.05 | Effect of 5-hydroxytryptophan on serum cortisol levels in major affective disorders. III. Effect of antidepressants and lithium carbonate. ( Goodnick, P; Lowy, M; Meltzer, HY; Perline, R; Robertson, A, 1984) |
| "Serum cortisol levels were significantly higher after administration of 5-hydroxytryptophan (5-HTP), 200 mg orally, in unmedicated patients with affective disorders than in controls." | 5.05 | Effect of 5-hydroxytryptophan on serum cortisol levels in major affective disorders. II. Relation to suicide, psychosis, and depressive symptoms. ( Lowy, M; Meltzer, HY; Perline, R; Robertson, A; Tricou, BJ, 1984) |
| " Following a discussion of the pharmacology of 5-HTP, the authors highlight adverse effects associated with its administration to depressed patients, neurologic subjects, and normal individuals." | 3.76 | 5-Hydroxytryptophan: a review of its antidepressant efficacy and adverse effects. ( Byerley, WF; Grosser, BI; Judd, LL; Reimherr, FW, 1987) |
| "A patient suffering from endogenous depression was treated with mianserin and developed agranulocytosis." | 3.68 | [Mianserin agranulocytosis followed by oxitriptan eosinophilia]. ( García, C, 1992) |
| "Demented patients with Parkinson's disease, particularly those with concurrent depression, had the lowest values of 5-HIAA." | 2.66 | The relationship of serotonin to depression in Parkinson's disease. ( Cote, LJ; Mayeux, R; Sano, M; Stern, Y; Williams, JB, 1988) |
| " Patients in each group received chlorimipramine (50 mg/day), combined with L-5-HTP (300 mg/day) in Group A, and with placebo in Group B." | 2.65 | Treatment of depression with L-5-hydroxytryptophan combined with chlorimipramine, a double-blind study. ( Battistini, N; Borghesi, R; De Stefano, R; Iannuccelli, M; Nardini, M, 1983) |
| "Chromium has a beneficial effect on eating-related atypical symptoms of depression, and may be a valuable agent in treating atypical depression and seasonal affective disorder." | 2.47 | Second-tier natural antidepressants: review and critique. ( Dalton, ED; Fava, M; Iovieno, N; Mischoulon, D, 2011) |
| " Extensive analyses of several sources of 5-HTP have shown no toxic contaminants similar to those associated with L-Trp, nor the presence of any other significant impurities." | 2.42 | Safety of 5-hydroxy-L-tryptophan. ( Bagchi, D; Bagchi, M; Das, YT; Preuss, HG, 2004) |
| " 5-HTP is well absorbed from an oral dose, with about 70 percent ending up in the bloodstream." | 2.40 | 5-Hydroxytryptophan: a clinically-effective serotonin precursor. ( Birdsall, TC, 1998) |
| "l-5-hydroxytryptophan was administered to 119 prepubertal children free of psychiatric disorder as part of a psychobiological cohort study initially designed to examine familial loading for mood disorder as the exposure of interest." | 1.32 | Gastrointestinal distress to serotonergic challenge: a risk marker for emotional disorder? ( Birmaher, B; Campo, JV; Dahl, RE; Perel, JM; Ryan, ND; Williamson, DE, 2003) |
| "A patient suffering from endogenous depression was treated with mianserin and developed agranulocytosis." | 1.28 | [Mianserin agranulocytosis followed by oxitriptan eosinophilia]. ( García, C, 1992) |
| "In the major depressives with melancholia and/or psychotic features these differences were reversed: women exhibited significantly higher cortisol and PRL responses than men." | 1.28 | Sex-linked differences in cortisol, ACTH and prolactin responses to 5-hydroxy-tryptophan in healthy controls and minor and major depressed patients. ( Blockx, P; Maes, L; Maes, M; Martin, M; Schotte, C; Vandewoude, M, 1989) |
| " However, possible toxic effects of high and long term use render its clinical use doubtful." | 1.27 | [Serotonin precursors as antidepressive agents: a review]. ( Beckmann, H; Kasper, S, 1983) |
| "In an open study 25 depressed patients were treated with L-5-hydroxytryptophan (L-5-HTP) either alone or in combination with a peripheral decarboxylase inhibitor." | 1.27 | L-5-hydroxytryptophan alone and in combination with a peripheral decarboxylase inhibitor in the treatment of depression. ( Battegay, R; Gastpar, M; Zmilacher, K, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 48 (61.54) | 18.7374 |
| 1990's | 21 (26.92) | 18.2507 |
| 2000's | 6 (7.69) | 29.6817 |
| 2010's | 3 (3.85) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Eskelund, A | 1 |
| Budac, DP | 1 |
| Sanchez, C | 1 |
| Elfving, B | 1 |
| Wegener, G | 1 |
| Iovieno, N | 1 |
| Dalton, ED | 1 |
| Fava, M | 1 |
| Mischoulon, D | 1 |
| Jangid, P | 1 |
| Malik, P | 1 |
| Singh, P | 1 |
| Sharma, M | 1 |
| Gulia, AK | 1 |
| Shaw, K | 1 |
| Turner, J | 1 |
| Del Mar, C | 1 |
| KLINE, NS | 2 |
| SACKS, W | 2 |
| SIMPSON, GM | 1 |
| COPPEN, A | 1 |
| SHAW, DM | 1 |
| MALLESON, A | 1 |
| Campo, JV | 1 |
| Dahl, RE | 3 |
| Williamson, DE | 2 |
| Birmaher, B | 3 |
| Perel, JM | 2 |
| Ryan, ND | 3 |
| Kubera, M | 2 |
| Kenis, G | 2 |
| Bosmans, E | 2 |
| Kajta, M | 1 |
| Basta-Kaim, A | 1 |
| Scharpe, S | 2 |
| Budziszewska, B | 1 |
| Maes, M | 7 |
| Das, YT | 1 |
| Bagchi, M | 1 |
| Bagchi, D | 1 |
| Preuss, HG | 1 |
| Freeman, MP | 1 |
| Helgason, C | 1 |
| Hill, RA | 1 |
| Gelenberg, AJ | 1 |
| Gibson, CJ | 1 |
| Wojcik, JD | 1 |
| van Praag, HM | 11 |
| de Haan, S | 1 |
| Mann, JJ | 1 |
| Meltzer, HY | 8 |
| Nardini, M | 1 |
| De Stefano, R | 1 |
| Iannuccelli, M | 1 |
| Borghesi, R | 1 |
| Battistini, N | 1 |
| Lowy, M | 4 |
| Robertson, A | 4 |
| Goodnick, P | 1 |
| Perline, R | 3 |
| Willner, P | 1 |
| Mendlewicz, J | 1 |
| Youdim, MB | 1 |
| Beckmann, H | 2 |
| Kasper, S | 1 |
| Tricou, BJ | 3 |
| Umberkoman-Wiita, B | 1 |
| Aprison, MH | 1 |
| Hingtgen, JN | 1 |
| Kent, S | 1 |
| Westenberg, HG | 1 |
| de Jong, JT | 1 |
| Thijssen, JH | 1 |
| Thompson, PA | 1 |
| Agren, H | 4 |
| Reibring, L | 4 |
| Goodnick, PJ | 1 |
| Sandoval, R | 1 |
| Arranz, B | 1 |
| Blennow, K | 1 |
| Eriksson, A | 1 |
| Månsson, JE | 1 |
| Marcusson, J | 1 |
| Nakajima, T | 1 |
| Meltzer, H | 1 |
| Bastani, B | 1 |
| Jayathilake, K | 1 |
| Kaufman, J | 2 |
| Brent, DA | 1 |
| al-Shabbout, M | 2 |
| Nelson, B | 1 |
| Stull, S | 2 |
| Rao, U | 1 |
| Waterman, GS | 1 |
| Birdsall, TC | 1 |
| Baumann, MH | 1 |
| Rothman, RB | 1 |
| Perel, J | 1 |
| Brent, D | 1 |
| Trubnick, L | 1 |
| Lin, AH | 1 |
| van Bockstaele, D | 1 |
| Hartvig, P | 3 |
| Tedroff, J | 3 |
| Bjurling, P | 3 |
| Lundqvist, H | 2 |
| Långström, B | 3 |
| Cho, WK | 1 |
| Stollerman, GH | 1 |
| García, C | 1 |
| Ulin, J | 1 |
| Hörnfeldt, K | 1 |
| Andersson, Y | 1 |
| Pöldinger, W | 2 |
| Calanchini, B | 1 |
| Schwarz, W | 1 |
| Bhushan, B | 1 |
| Seth, SD | 1 |
| Saxena, S | 1 |
| Gupta, YK | 1 |
| Karmarkar, MG | 1 |
| D'Hondt, P | 1 |
| Martin, M | 3 |
| Claes, M | 1 |
| Schotte, C | 3 |
| Vandewoude, M | 3 |
| Blockx, P | 3 |
| Asnis, GM | 2 |
| Kahn, RS | 2 |
| Brown, SL | 2 |
| Korn, M | 1 |
| Friedman, JM | 1 |
| Wetzler, S | 1 |
| Maes, L | 2 |
| Byerley, WF | 2 |
| Risch, SC | 1 |
| López-Ibor, JJ | 1 |
| Saiz-Ruiz, J | 1 |
| Pérez de los Cobos, JC | 1 |
| Kahn, R | 1 |
| Lemus, CZ | 1 |
| Koyama, T | 1 |
| Lowy, MT | 1 |
| Mayeux, R | 1 |
| Stern, Y | 1 |
| Sano, M | 1 |
| Williams, JB | 1 |
| Cote, LJ | 1 |
| Riederer, P | 1 |
| Brücke, T | 1 |
| Nolen, WA | 3 |
| Kielholz, P | 1 |
| Asberg, M | 1 |
| Eriksson, B | 1 |
| Mårtensson, B | 1 |
| Träskman-Bendz, L | 1 |
| Wägner, A | 1 |
| Metz, JT | 1 |
| Holcomb, HH | 1 |
| Conte, G | 1 |
| van de Putte, JJ | 2 |
| Dijken, WA | 2 |
| Kamp, JS | 2 |
| Blansjaar, BA | 1 |
| Kramer, HJ | 1 |
| Haffmans, J | 1 |
| Calanca, A | 1 |
| Zmilacher, K | 1 |
| Battegay, R | 1 |
| Gastpar, M | 1 |
| Judd, LL | 1 |
| Reimherr, FW | 1 |
| Grosser, BI | 1 |
| Leander, JD | 1 |
| Fuller, RW | 1 |
| Hippius, H | 1 |
| Matussek, N | 1 |
| Jacobsen, FM | 1 |
| Sack, DA | 1 |
| Wehr, TA | 1 |
| Rogers, S | 1 |
| Rosenthal, NE | 1 |
| Lieberman, JA | 1 |
| Kane, JM | 1 |
| Reife, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Rhodiola Rosea in Adults With Attention Deficit/Hyperactivity Disorder[NCT02737020] | Phase 4 | 60 participants (Anticipated) | Interventional | 2016-04-30 | Recruiting | ||
| Effects of 800mg of Rhodiola Rosea in Attention in Adults With Attention-Deficit/Hyperactivity Disorder[NCT02737033] | Phase 4 | 60 participants (Anticipated) | Interventional | 2016-04-30 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
21 reviews available for 5-hydroxytryptophan and Depression, Endogenous
| Article | Year |
|---|---|
Second-tier natural antidepressants: review and critique.
Topics: 5-Hydroxytryptophan; Antidepressive Agents; Chromium; Complementary Therapies; Depressive Disorder; | 2011 |
Second-tier natural antidepressants: review and critique.
Topics: 5-Hydroxytryptophan; Antidepressive Agents; Chromium; Complementary Therapies; Depressive Disorder; | 2011 |
Second-tier natural antidepressants: review and critique.
Topics: 5-Hydroxytryptophan; Antidepressive Agents; Chromium; Complementary Therapies; Depressive Disorder; | 2011 |
Second-tier natural antidepressants: review and critique.
Topics: 5-Hydroxytryptophan; Antidepressive Agents; Chromium; Complementary Therapies; Depressive Disorder; | 2011 |
Are tryptophan and 5-hydroxytryptophan effective treatments for depression? A meta-analysis.
Topics: 5-Hydroxytryptophan; Depressive Disorder; Humans; Randomized Controlled Trials as Topic; Treatment O | 2002 |
Safety of 5-hydroxy-L-tryptophan.
Topics: 5-Hydroxytryptophan; Adult; Animals; Antidepressive Agents; Depressive Disorder; Drug Contamination; | 2004 |
Selected integrative medicine treatments for depression: considerations for women.
Topics: 5-Hydroxytryptophan; Acupuncture Therapy; Complementary Therapies; Depressive Disorder; Exercise The | 2004 |
Neurotransmitter precursors for the treatment of depression.
Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Biogenic Amines; Catecholamines; Depressive Dis | 1982 |
In search of the mode of action of antidepressants. 5-HTP/tyrosine mixtures in depressions.
Topics: 5-Hydroxytryptophan; Adult; Antidepressive Agents; Biogenic Amines; Brain Chemistry; Depressive Diso | 1983 |
Serotonergic function in the affective disorders: the effect of antidepressants and lithium on the 5-hydroxytryptophan-induced increase in serum cortisol.
Topics: 5-Hydroxytryptophan; Antidepressive Agents; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depr | 1984 |
The validity of animal models of depression.
Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Behavior, Animal; Circadian Rhythm; Depressive Disorder; | 1984 |
Serotonin precursors in the treatment of depression.
Topics: 5-Hydroxytryptophan; Antidepressive Agents; Brain Diseases; Depressive Disorder; Humans; Serotonin; | 1982 |
Significance of serotonin precursors as antidepressants.
Topics: 5-Hydroxytryptophan; Animals; Antidepressive Agents; Depressive Disorder; Humans; Serotonin; Tryptop | 1982 |
Psychotropic treatment of chronic fatigue syndrome and related disorders.
Topics: 5-Hydroxytryptophan; Amitriptyline; Antidepressive Agents, Tricyclic; Comorbidity; Depressive Disord | 1993 |
Amine precursor amino acid therapy: from neurochemical basis to clinical aspects.
Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Depressive Disorder; Droxidopa; Histidine; Humans; Levodo | 1996 |
5-Hydroxytryptophan: a clinically-effective serotonin precursor.
Topics: 5-Hydroxytryptophan; Contraindications; Depressive Disorder; Fibromyalgia; Headache; Humans; Obesity | 1998 |
Chronic fatigue syndrome.
Topics: 5-Hydroxytryptophan; Adult; Clinical Protocols; Decision Trees; Depressive Disorder; Diagnosis, Diff | 1992 |
Nosological tunnel vision in biological psychiatry. A plea for a functional psychopathology.
Topics: 5-Hydroxytryptophan; Aggression; Biology; Depression; Depressive Disorder; Humans; Mental Disorders; | 1990 |
Depression and serotonin metabolism: rationale for neurotransmitter precursor treatment.
Topics: 5-Hydroxytryptophan; Antidepressive Agents, Tricyclic; Blood Platelets; Brain Chemistry; Depressive | 1985 |
Affective disorders and aggression disorders: evidence for a common biological mechanism.
Topics: 5-Hydroxytryptophan; Aggression; Blood Platelets; Carrier Proteins; Celiac Disease; Depressive Disor | 1986 |
Therapeutic effects of serotonin uptake inhibitors in depression.
Topics: 5-Hydroxytryptophan; Alanine; Citalopram; Depressive Disorder; Fluoxetine; Fluvoxamine; Humans; Imip | 1986 |
L-5-hydroxytryptophan in depression and anxiety.
Topics: 5-Hydroxytryptophan; Anxiety Disorders; Depressive Disorder; Humans; Panic; Receptors, Serotonin | 1988 |
5-Hydroxytryptophan: a review of its antidepressant efficacy and adverse effects.
Topics: 5-Hydroxytryptophan; Carbidopa; Clinical Trials as Topic; Depressive Disorder; Humans | 1987 |
Neuromuscular effects of monoamine oxidase inhibitors.
Topics: 5-Hydroxytryptophan; Adult; Animals; Clomipramine; Clorgyline; Depressive Disorder; Female; Humans; | 1986 |
16 trials available for 5-hydroxytryptophan and Depression, Endogenous
| Article | Year |
|---|---|
Comparative study of efficacy of l-5-hydroxytryptophan and fluoxetine in patients presenting with first depressive episode.
Topics: 5-Hydroxytryptophan; Adult; Antidepressive Agents, Second-Generation; Depressive Disorder; Double-Bl | 2013 |
In search of the mode of action of antidepressants: 5-HTP/tyrosine mixtures in depression.
Topics: 5-Hydroxytryptophan; Adult; Antidepressive Agents; Biogenic Amines; Bipolar Disorder; Clinical Trial | 1984 |
Treatment of depression with L-5-hydroxytryptophan combined with chlorimipramine, a double-blind study.
Topics: 5-Hydroxytryptophan; Adult; Aged; Clinical Trials as Topic; Clomipramine; Depressive Disorder; Doubl | 1983 |
Effect of 5-hydroxytryptophan on serum cortisol levels in major affective disorders. III. Effect of antidepressants and lithium carbonate.
Topics: 5-Hydroxytryptophan; Antidepressive Agents; Antidepressive Agents, Tricyclic; Bipolar Disorder; Depr | 1984 |
Antidepressant potentiation of 5-hydroxytryptophan by L-deprenil in affective illness.
Topics: 5-Hydroxytryptophan; Adult; Bipolar Disorder; Depressive Disorder; Double-Blind Method; Drug Therapy | 1980 |
Effect of 5-hydroxytryptophan on serum cortisol levels in major affective disorders. II. Relation to suicide, psychosis, and depressive symptoms.
Topics: 5-Hydroxytryptophan; Bipolar Disorder; Depressive Disorder; Humans; Hydrocortisone; Mood Disorders; | 1984 |
Effect of the placebo control condition in neuroendocrine challenge studies.
Topics: 5-Hydroxytryptophan; Antipsychotic Agents; Apomorphine; Bias; Buspirone; Data Interpretation, Statis | 1994 |
Fluoxetine, but not tricyclic antidepressants, potentiates the 5-hydroxytryptophan-mediated increase in plasma cortisol and prolactin secretion in subjects with major depression or with obsessive compulsive disorder.
Topics: 5-Hydroxytryptophan; Adult; Age Factors; Antidepressive Agents, Second-Generation; Antidepressive Ag | 1997 |
Serotonergic functioning in depressed abused children: clinical and familial correlates.
Topics: 5-Hydroxytryptophan; Child; Child Abuse; Depressive Disorder; Female; Humans; Hydrocortisone; Male; | 1998 |
A functional-dimensional approach to depression: serotonin deficiency as a target syndrome in a comparison of 5-hydroxytryptophan and fluvoxamine.
Topics: 5-Hydroxytryptophan; Adult; Aged; Aged, 80 and over; Antidepressive Agents; Brain; Depressive Disord | 1991 |
The relationship of serotonin to depression in Parkinson's disease.
Topics: 5-Hydroxytryptophan; Aged; Clinical Trials as Topic; Dementia; Depressive Disorder; Female; Humans; | 1988 |
Tranylcypromine in depression resistant to cyclic antidepressions.
Topics: 5-Hydroxytryptophan; Adult; Clinical Trials as Topic; Depressive Disorder; Double-Blind Method; Drug | 1989 |
Treatment strategy in depression. II. MAO inhibitors in depression resistant to cyclic antidepressants: two controlled crossover studies with tranylcypromine versus L-5-hydroxytryptophan and nomifensine.
Topics: 5-Hydroxytryptophan; Adult; Aged; Clinical Trials as Topic; Depressive Disorder; Dose-Response Relat | 1988 |
5-Hydroxytryptophan: a review of its antidepressant efficacy and adverse effects.
Topics: 5-Hydroxytryptophan; Carbidopa; Clinical Trials as Topic; Depressive Disorder; Humans | 1987 |
Neuroendocrine response to 5-hydroxytryptophan in seasonal affective disorder.
Topics: 5-Hydroxytryptophan; Adult; Blood Pressure; Depressive Disorder; Female; Growth Hormone; Humans; Hyd | 1987 |
L-5HTP in depression resistant to re-uptake inhibitors. An open comparative study with tranylcypromine.
Topics: 5-Hydroxytryptophan; Adult; Aged; Carbidopa; Clinical Trials as Topic; Depressive Disorder; Drug Res | 1985 |
42 other studies available for 5-hydroxytryptophan and Depression, Endogenous
| Article | Year |
|---|---|
Female Flinders Sensitive Line rats show estrous cycle-independent depression-like behavior and altered tryptophan metabolism.
Topics: 5-Hydroxytryptophan; Animals; Anxiety; Brain; Depressive Disorder; Disease Models, Animal; Estrous C | 2016 |
Relief of depression within one day using an M.A.O. inhibitor and intravenous 5-HTP.
Topics: 5-Hydroxytryptophan; Depression; Depressive Disorder; Humans; Indoles; Monoamine Oxidase Inhibitors | 1963 |
FURTHER STUDIES ON: ONE DAY TREATMENT OF DEPRESSION WITH 5-HTP.
Topics: 5-Hydroxytryptophan; Biomedical Research; Depression; Depressive Disorder; Drug Therapy; Geriatrics; | 1964 |
CHANGES IN 5-HYDROXYTRYPTOPHAN METABOLISM IN DEPRESSION.
Topics: 5-Hydroxytryptophan; Amino Acids; Depression; Depressive Disorder; Humans | 1965 |
Gastrointestinal distress to serotonergic challenge: a risk marker for emotional disorder?
Topics: 5-Hydroxytryptophan; Affective Symptoms; Anxiety Disorders; Child; Cohort Studies; Depressive Disord | 2003 |
Stimulatory effect of antidepressants on the production of IL-6.
Topics: 5-Hydroxytryptophan; Adult; Age Factors; Aging; Antidepressive Agents; Blood Cells; Cyclohexanols; D | 2004 |
Chemoprophylaxis of depressions. An attempt to compare lithium with 5-hydroxytryptophan.
Topics: 5-Hydroxytryptophan; Adult; Depressive Disorder; Female; Humans; Hydroxyindoleacetic Acid; Lithium; | 1981 |
Management of depression with serotonin precursors.
Topics: 5-Hydroxytryptophan; Depressive Disorder; Dose-Response Relationship, Drug; Humans; Hydroxyindoleace | 1981 |
Loss of antidepressant effect with long-term monoamine oxidase inhibitor treatment without loss of monoamine oxidase inhibition.
Topics: 5-Hydroxytryptophan; Brain Chemistry; Depressive Disorder; Drug Tolerance; Humans; Monoamine Oxidase | 1983 |
[Serotonin precursors as antidepressive agents: a review].
Topics: 5-Hydroxytryptophan; Climacteric; Depression; Depressive Disorder; Female; Humans; Tryptophan | 1983 |
Hormone response to 5-HTP.
Topics: 5-Hydroxytryptophan; Depressive Disorder; Growth Hormone; Humans; Hydrocortisone; Prolactin | 1983 |
Effect of 5-hydroxytryptophan on serum cortisol levels in major affective disorders. I. Enhanced response in depression and mania.
Topics: 5-Hydroxytryptophan; Administration, Oral; Adult; Bipolar Disorder; Brain Chemistry; Depressive Diso | 1984 |
Hypersensitive serotonergic receptors: a new hypothesis for one subgroup of unipolar depression derived from an animal model.
Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Brain; Columbidae; Depressive Disorder; Disease Mode | 1981 |
New treatments for depression.
Topics: 5-Hydroxytryptophan; Amino Acids; Antidepressive Agents, Tricyclic; Depressive Disorder; Humans; Nor | 1982 |
Postsynaptic serotonergic activity in depressive patients: evaluation of the neuroendocrine strategy.
Topics: 5-Hydroxytryptophan; Adult; Bipolar Disorder; Blood Glucose; Depressive Disorder; Female; Growth Hor | 1982 |
PET studies of presynaptic monoamine metabolism in depressed patients and healthy volunteers.
Topics: 5-Hydroxytryptophan; Animals; Brain; Depressive Disorder; Humans; Levodopa; Presynaptic Terminals; T | 1994 |
Serotonergic, noradrenergic, and dopaminergic measures in suicide brains.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Adult; Brain; Depressive Disorder; Dopamine; Fe | 1997 |
Neuroendocrine response to 5-hydroxy-L-tryptophan in prepubertal children at high risk of major depressive disorder.
Topics: 5-Hydroxytryptophan; Adult; Child; Depressive Disorder; Female; Genetic Markers; Human Growth Hormon | 1997 |
5-hydroxytryptophan.
Topics: 5-Hydroxytryptophan; Contraindications; Depressive Disorder; Fibromyalgia; Headache; Humans; Obesity | 1998 |
Alterations in serotonergic responsiveness during cocaine withdrawal in rats: similarities to major depression in humans.
Topics: 5-Hydroxytryptophan; 8-Hydroxy-2-(di-n-propylamino)tetralin; Amphetamines; Animals; Behavior, Animal | 1998 |
Anti-Inflammatory effects of antidepressants through suppression of the interferon-gamma/interleukin-10 production ratio.
Topics: 5-Hydroxytryptophan; Adult; Analysis of Variance; Antidepressive Agents; Cyclohexanols; Depressive D | 2001 |
PET studies with L-[11C]5-HTP and L-[11C]dopa in brains of healthy volunteers and patients with major depression.
Topics: 5-Hydroxytryptophan; Adult; Aged; Brain; Brain Chemistry; Carbon Isotopes; Depressive Disorder; Dihy | 1992 |
[Mianserin agranulocytosis followed by oxitriptan eosinophilia].
Topics: 5-Hydroxytryptophan; Agranulocytosis; Blood Cell Count; Depressive Disorder; Eosinophilia; Eosinophi | 1992 |
Positron emission tomography of [11C]5-hydroxytryptophan utilization in the brains of healthy volunteers and a patient with major depression.
Topics: 5-Hydroxytryptophan; Adult; Brain; Carbon Radioisotopes; Depressive Disorder; Female; Humans; Male; | 1991 |
Low brain uptake of L-[11C]5-hydroxytryptophan in major depression: a positron emission tomography study on patients and healthy volunteers.
Topics: 5-Hydroxytryptophan; Adult; Antidepressive Agents; Basal Ganglia; Blood-Brain Barrier; Brain; Combin | 1991 |
An adverse reaction to L-5-hydroxytryptophan.
Topics: 5-Hydroxytryptophan; Adult; Depressive Disorder; Dermatitis, Atopic; Drug Hypersensitivity; Humans; | 1991 |
L-5-hydroxytryptophan stimulated cortisol escape from dexamethasone suppression in melancholic patients.
Topics: 5-Hydroxytryptophan; Adult; Aged; Analysis of Variance; Depressive Disorder; Dexamethasone; Female; | 1991 |
The relationships between the cortisol responses to dexamethasone and to L-5-HTP, and the availability of L-tryptophan in depressed females.
Topics: 5-Hydroxytryptophan; Adult; Depressive Disorder; Dexamethasone; Female; Humans; Hydrocortisone; Hypo | 1990 |
Biological correlations of suicide and aggressivity in major depressions (with melancholia): 5-hydroxyindoleacetic acid and cortisol in cerebral spinal fluid, dexamethasone suppression test and therapeutic response to 5-hydroxytryptophan.
Topics: 5-Hydroxytryptophan; Adult; Aggression; Bipolar Disorder; Carbidopa; Depressive Disorder; Dexamethas | 1985 |
Therapeutic indications for serotonin-potentiating compounds: a hypothesis.
Topics: 5-Hydroxytryptophan; Aggression; Antidepressive Agents; Anxiety; Brain; Depressive Disorder; Desipra | 1987 |
5-Hydroxytryptophan-induced cortisol response and CSF 5-HIAA in depressed patients.
Topics: 3,4-Dihydroxyphenylacetic Acid; 5-Hydroxytryptophan; Adult; Brain; Depressive Disorder; Female; Homo | 1987 |
Sex-linked differences in cortisol, ACTH and prolactin responses to 5-hydroxy-tryptophan in healthy controls and minor and major depressed patients.
Topics: 5-Hydroxytryptophan; Adrenocorticotropic Hormone; Adult; Aged; Depressive Disorder; Female; Humans; | 1989 |
[Current biochemical hypotheses of endogenous depression].
Topics: 5-Hydroxytryptophan; Amitriptyline; Autopsy; Biogenic Amines; Bipolar Disorder; Brain; Depressive Di | 1985 |
Treatment for therapy-resistant depression.
Topics: 5-Hydroxytryptophan; Antidepressive Agents; Antipsychotic Agents; Combined Modality Therapy; Depress | 1986 |
Effect of 5-hydroxytryptophan on H-reflex recovery curves in normal subjects and patients with affective disorders.
Topics: 5-Hydroxytryptophan; Adolescent; Adult; Antidepressive Agents; Arousal; Bipolar Disorder; Brain; Dep | 1988 |
Lithium, imipramine and hydroxytryptophan in resistant depression.
Topics: 5-Hydroxytryptophan; Adult; Depressive Disorder; Drug Therapy, Combination; Humans; Imipramine; Lith | 1988 |
[Guidelines in the treatment of depression in the hospital and in family practice].
Topics: 5-Hydroxytryptophan; Antidepressive Agents; Chronobiology Phenomena; Combined Modality Therapy; Depr | 1988 |
[Hydroxytryptophan (oxitriptan) associated with classical antidepressants: an additional therapeutic possibility].
Topics: 5-Hydroxytryptophan; Antidepressive Agents; Depressive Disorder; Drug Synergism; Drug Therapy, Combi | 1988 |
L-5-hydroxytryptophan alone and in combination with a peripheral decarboxylase inhibitor in the treatment of depression.
Topics: 5-Hydroxytryptophan; Adult; Aged; Benserazide; Bipolar Disorder; Depressive Disorder; Dose-Response | 1988 |
Peripheral action of serotonin as a model of depression.
Topics: 5-Hydroxytryptophan; Amidines; Animals; Blood-Brain Barrier; Conditioning, Operant; Depression, Chem | 1986 |
Pharmacologic properties of serotonergic agents and antidepressant drugs.
Topics: 5-Hydroxytryptophan; Antidepressive Agents; Brain; Depressive Disorder; Humans; Monoamine Oxidase In | 1987 |
Remarks on the therapy of depressions with amine precursors.
Topics: 5-Hydroxytryptophan; Depressive Disorder; Drug Therapy, Combination; Humans; Lithium; Monoamine Oxid | 1986 |