Page last updated: 2024-10-16

5-hydroxytryptophan and Decerebrate Posturing

5-hydroxytryptophan has been researched along with Decerebrate Posturing in 26 studies

5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.

Research Excerpts

ExcerptRelevanceReference
"Amitriptyline (AMI) was studied in rats snd mice in order to find out whether it had a central antiserotonin activity, previously demonstrated for doxepin - a compound chemically related to AMI."1.26Central antiserotonin action of amitriptyline. ( Lewandowska, A; Maj, J; Rawtów, A, 1979)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199018 (69.23)18.7374
1990's6 (23.08)18.2507
2000's1 (3.85)29.6817
2010's1 (3.85)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Meehan, CF1
Grondahl, L1
Nielsen, JB1
Hultborn, H3
Iles, JF1
Nicolopoulos-Stournaras, S1
Paroschy, KL1
Shefchyk, SJ1
Bell, JA1
Martin, WR2
Sloan, JW2
Buchwald, WF1
Wang, RY1
Aghajanian, GK1
Thut, PD1
Myslinski, NR2
Slater, IH1
Jones, GT1
Moore, RA1
Tadepalli, AS1
Mills, E1
Schanberg, SM1
Ternaux, JP1
Hery, F1
Hamon, M1
Bourgoin, S1
Glowinski, J1
Commissiong, JW1
Sedgwick, EM1
Maj, J2
Lewandowska, A1
Rawtów, A1
Miller, S1
Van Der Burg, J1
Van Der Meché, F1
Palider, W1
Baran, L1
Sastry, BS1
Sinclair, JG1
Mitchell, GS1
Sloan, HE1
Jiang, C1
Miletic, V1
Hayashi, F1
Lipski, J1
Skarsfeldt, T1
Arnt, J1
Hyttel, J1
Rawlow, A1
King, RG1
Barbeau, H1
Rossignol, S1
Tremblay, LE1
Bédard, PJ1
Nagano, N1
Ono, H1
Ozawa, M1
Fukuda, H1
Davey, NJ1
Ellaway, PH1
Crone, C1
Kiehn, O2
Mazieres, L1
Wigström, H1
Hounsgaard, J1
Jespersen, B1
Armijo, JA1
Flórez, J1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Priming With High-Frequency Trans-spinal Stimulation to Augment Locomotor Benefits in Spinal Cord Injury[NCT04807764]45 participants (Anticipated)Interventional2021-08-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

26 other studies available for 5-hydroxytryptophan and Decerebrate Posturing

ArticleYear
Fictive locomotion in the adult decerebrate and spinal mouse in vivo.
    The Journal of physiology, 2012, Jan-15, Volume: 590, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Cats; Decerebrate State; Electric Stimulation; Female; Haplorhini; Lev

2012
Fictive locomotion in the adult decerebrate rat.
    Experimental brain research, 1996, Volume: 109, Issue:3

    Topics: 5-Hydroxytryptophan; Age Factors; Animals; Decerebrate State; Dopamine Agents; Efferent Pathways; El

1996
Non-linear membrane properties of sacral sphincter motoneurones in the decerebrate cat.
    The Journal of physiology, 2000, Mar-15, Volume: 523 Pt 3

    Topics: 5-Hydroxytryptophan; Anal Canal; Animals; Cats; Cell Membrane; Decerebrate State; Electric Stimulati

2000
The effect of L-tryptophan on spinal cord C-fiber reflexes.
    The Journal of pharmacology and experimental therapeutics, 1976, Volume: 196, Issue:2

    Topics: 5-Hydroxytryptophan; Action Potentials; Animals; Carboxy-Lyases; Cats; Cyproheptadine; Decerebrate S

1976
Inhibiton of neurons in the amygdala by dorsal raphe stimulation: mediation through a direct serotonergic pathway.
    Brain research, 1977, Jan-14, Volume: 120, Issue:1

    Topics: 5-Hydroxytryptophan; Action Potentials; Amygdala; Animals; Brain Stem; Cyproheptadine; Decerebrate S

1977
The role of dopamine and serotonin in the prolongation of post-decapitation convulsions in mice.
    Life sciences, 1976, Nov-15, Volume: 19, Issue:10

    Topics: 5-Hydroxytryptophan; Animals; Benserazide; Brain; Decerebrate State; Ditiocarb; Dopamine; Fenclonine

1976
Inhibition of REM sleep by fluoxetine, a specific inhibitor of serotonin uptake.
    Neuropharmacology, 1978, Volume: 17, Issue:6

    Topics: 5-Hydroxytryptophan; Animals; Cats; Decerebrate State; Depression, Chemical; Electroencephalography;

1978
Central depression of carotid baroreceptor pressor response, arterial pressure and heart rate by 5-hydroxytryptophan: influence of supracollicular areas of the brain.
    The Journal of pharmacology and experimental therapeutics, 1977, Volume: 202, Issue:2

    Topics: 5-Hydroxytryptophan; Action Potentials; Animals; Benserazide; Blood Pressure; Brain; Carotid Arterie

1977
5-HT release from ependymal surface of the caudate nucleus in 'encéphale isolé' cats.
    Brain research, 1977, Sep-02, Volume: 132, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Cats; Caudate Nucleus; Decerebrate State; Ependyma; Female; Lysergic A

1977
Modulation of the tonic stretch reflex by monoamines.
    European journal of pharmacology, 1979, Jul-15, Volume: 57, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Apomorphine; Biogenic Amines; Cats; Decerebrate State; Electromyograph

1979
Central antiserotonin action of amitriptyline.
    Pharmakopsychiatrie, Neuro-Psychopharmakologie, 1979, Volume: 12, Issue:3

    Topics: 5-Hydroxytryptophan; Amitriptyline; Animals; Behavior, Animal; Central Nervous System; Decerebrate S

1979
Locomotion in the cat: basic programmes of movement.
    Brain research, 1975, Jun-27, Volume: 91, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Cats; Clonidine; Decerebrate State; Forelimb; Gait; Hindlimb; Levodopa

1975
The effects of serotonergic and antiserotonergic drugs on the flexor reflex of spinal rat: a proposed model to evaluate the action on the central serotonin receptor.
    Journal of neural transmission, 1976, Volume: 38, Issue:2

    Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Anthracenes; Clonidine; Cyproheptadine; Decerebrate State

1976
Serotonin involvement in the blockade of bulbospinal inhibition of the spinal monosynaptic reflex.
    Brain research, 1976, Oct-22, Volume: 115, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Blood Pressure; Cats; Cyproheptadine; Decerebrate State; Dose-Response

1976
5-Hydroxytryptophan (5-HTP) augments spontaneous and evoked phrenic motoneuron discharge in spinalized rats.
    Neuroscience letters, 1992, Jul-06, Volume: 141, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Decerebrate State; Evoked Potentials; Methysergide; Motor Neurons; Phr

1992
The involvement of bulbospinal serotonergic neurons in the effect of 5-hydroxytryptophan on alpha and gamma motoneurons.
    Advances in experimental medicine and biology, 1991, Volume: 294

    Topics: 5-Hydroxytryptophan; Animals; Cats; Cinanserin; Decerebrate State; Drug Synergism; Female; Fenclonin

1991
L-5-HTP facilitates the electrically stimulated flexor reflex in pithed rats: evidence for 5-HT2-receptor mediation.
    European journal of pharmacology, 1990, Feb-06, Volume: 176, Issue:2

    Topics: 5-Hydroxytryptophan; Amphetamines; Animals; Antipsychotic Agents; Benserazide; Citalopram; Decerebra

1990
A novel in vivo test for drugs affecting central serotonergic and adrenergic systems.
    European journal of pharmacology, 1990, Dec-04, Volume: 191, Issue:3

    Topics: 5-Hydroxytryptophan; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Albuterol; Animals; Cl

1990
The effects of serotonergic drugs on the locomotor pattern and on cutaneous reflexes of the adult chronic spinal cat.
    Brain research, 1990, Apr-23, Volume: 514, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Cats; Decerebrate State; Locomotion; Methoxydimethyltryptamines; Motor

1990
Chronic administration of thyrotropin-releasing hormone enhances the sensitivity of lumbar motoneurons to 5-hydroxytryptophan in the rat.
    Pharmacology, biochemistry, and behavior, 1989, Volume: 33, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Body Weight; Decerebrate State; Electromyography; Female; Motor Neuron

1989
Relationship of CNS tryptaminergic processes and the action of LSD-like hallucinogens.
    Pharmacology, biochemistry, and behavior, 1986, Volume: 24, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Behavior, Animal; Blood Pressure; Brain Chemistry; Central Nervous Sys

1986
The spinal reflex of chronic spinal rats is supersensitive to 5-HTP but not to TRH or 5-HT agonists.
    European journal of pharmacology, 1988, May-10, Volume: 149, Issue:3

    Topics: 5-Hydroxytryptophan; Animals; Decerebrate State; Male; Methoxydimethyltryptamines; Radioimmunoassay;

1988
Control from the brainstem of synchrony of discharge between gamma motoneurones in the cat.
    Experimental brain research, 1988, Volume: 72, Issue:2

    Topics: 5-Hydroxytryptophan; Animals; Brain Stem; Cats; Decerebrate State; Hindlimb; Levodopa; Motor Neurons

1988
Maintained changes in motoneuronal excitability by short-lasting synaptic inputs in the decerebrate cat.
    The Journal of physiology, 1988, Volume: 405

    Topics: 5-Hydroxytryptophan; Animals; Cats; Decerebrate State; Electromyography; Hindlimb; Methysergide; Mot

1988
Bistability of alpha-motoneurones in the decerebrate cat and in the acute spinal cat after intravenous 5-hydroxytryptophan.
    The Journal of physiology, 1988, Volume: 405

    Topics: 5-Hydroxytryptophan; Action Potentials; Animals; Cats; Decerebrate State; Hindlimb; Membrane Potenti

1988
The influence of increased brain 5-hydroxytryptamine upon the respiratory activity of cats.
    Neuropharmacology, 1974, Volume: 13, Issue:10-11

    Topics: 5-Hydroxytryptophan; Amino Acids; Animals; Benserazide; Brain Chemistry; Carbon Dioxide; Carboxy-Lya

1974