5-hydroxytryptophan has been researched along with Cardiomegaly in 3 studies
5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
| Excerpt | Relevance | Reference |
|---|---|---|
| " These results suggest that chronic administration of L-5-HTP provides significant protection against the development of DOCA-induced hypertension, polydipsia, polyuria, and cardiac hypertrophy in rats." | 5.27 | Chronic treatment with L-5-hydroxytryptophan prevents the development of DOCA-salt-induced hypertension in rats. ( Fregly, MJ; Lockley, OE; Sumners, C, 1987) |
| " These results suggest that chronic administration of L-5-HTP was effective in reducing the elevated blood pressure in the DS model." | 1.28 | Reduction in the elevated blood pressure of Dahl salt-sensitive rats treated chronically with L-5-hydroxytryptophan. ( Baron, A; Fregly, MJ; Riesselmann, A, 1991) |
| "Cardiac hypertrophy was associated with Dahl salt-induced hypertension." | 1.28 | Reduction in the elevated blood pressure of Dahl salt-sensitive rats treated chronically with L-5-hydroxytryptophan. ( Baron, A; Fregly, MJ; Riesselmann, A, 1991) |
| " These results suggest that chronic administration of L-5-HTP provides significant protection against the development of DOCA-induced hypertension, polydipsia, polyuria, and cardiac hypertrophy in rats." | 1.27 | Chronic treatment with L-5-hydroxytryptophan prevents the development of DOCA-salt-induced hypertension in rats. ( Fregly, MJ; Lockley, OE; Sumners, C, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (66.67) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Baron, A | 1 |
| Riesselmann, A | 1 |
| Fregly, MJ | 2 |
| Lockley, OE | 1 |
| Sumners, C | 1 |
| O'Steen, WK | 1 |
| Hall, CE | 1 |
| Hall, OS | 1 |
3 other studies available for 5-hydroxytryptophan and Cardiomegaly
| Article | Year |
|---|---|
Reduction in the elevated blood pressure of Dahl salt-sensitive rats treated chronically with L-5-hydroxytryptophan.
Topics: 5-Hydroxytryptophan; Animals; Blood Pressure; Body Weight; Cardiomegaly; Desoxycorticosterone; Femal | 1991 |
Chronic treatment with L-5-hydroxytryptophan prevents the development of DOCA-salt-induced hypertension in rats.
Topics: 5-Hydroxytryptophan; Administration, Cutaneous; Angiotensin II; Animals; Cardiomegaly; Catecholamine | 1987 |
Hormone influenced hypertension in the male rat. Effect of hydrochlorothiazide.
Topics: 5-Hydroxytryptophan; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Cardiomegaly; Ce | 1969 |