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5-hydroxytryptophan and Cardiac Hypertrophy

5-hydroxytryptophan has been researched along with Cardiac Hypertrophy in 3 studies

5-Hydroxytryptophan: The immediate precursor in the biosynthesis of SEROTONIN from tryptophan. It is used as an antiepileptic and antidepressant.
5-hydroxytryptophan : A tryptophan derivative that is tryptophan substituted by a hydroxy group at position 5.

Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.

Research Excerpts

ExcerptRelevanceReference
" These results suggest that chronic administration of L-5-HTP provides significant protection against the development of DOCA-induced hypertension, polydipsia, polyuria, and cardiac hypertrophy in rats."5.27Chronic treatment with L-5-hydroxytryptophan prevents the development of DOCA-salt-induced hypertension in rats. ( Fregly, MJ; Lockley, OE; Sumners, C, 1987)
" These results suggest that chronic administration of L-5-HTP was effective in reducing the elevated blood pressure in the DS model."1.28Reduction in the elevated blood pressure of Dahl salt-sensitive rats treated chronically with L-5-hydroxytryptophan. ( Baron, A; Fregly, MJ; Riesselmann, A, 1991)
"Cardiac hypertrophy was associated with Dahl salt-induced hypertension."1.28Reduction in the elevated blood pressure of Dahl salt-sensitive rats treated chronically with L-5-hydroxytryptophan. ( Baron, A; Fregly, MJ; Riesselmann, A, 1991)
" These results suggest that chronic administration of L-5-HTP provides significant protection against the development of DOCA-induced hypertension, polydipsia, polyuria, and cardiac hypertrophy in rats."1.27Chronic treatment with L-5-hydroxytryptophan prevents the development of DOCA-salt-induced hypertension in rats. ( Fregly, MJ; Lockley, OE; Sumners, C, 1987)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19902 (66.67)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Baron, A1
Riesselmann, A1
Fregly, MJ2
Lockley, OE1
Sumners, C1
O'Steen, WK1
Hall, CE1
Hall, OS1

Other Studies

3 other studies available for 5-hydroxytryptophan and Cardiac Hypertrophy

ArticleYear
Reduction in the elevated blood pressure of Dahl salt-sensitive rats treated chronically with L-5-hydroxytryptophan.
    Pharmacology, 1991, Volume: 42, Issue:1

    Topics: 5-Hydroxytryptophan; Animals; Blood Pressure; Body Weight; Cardiomegaly; Desoxycorticosterone; Femal

1991
Chronic treatment with L-5-hydroxytryptophan prevents the development of DOCA-salt-induced hypertension in rats.
    Journal of hypertension, 1987, Volume: 5, Issue:5

    Topics: 5-Hydroxytryptophan; Administration, Cutaneous; Angiotensin II; Animals; Cardiomegaly; Catecholamine

1987
Hormone influenced hypertension in the male rat. Effect of hydrochlorothiazide.
    Archives of pathology, 1969, Volume: 87, Issue:6

    Topics: 5-Hydroxytryptophan; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Cardiomegaly; Ce

1969